Molecular Biology of the Skin PDF Download
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Author: Michael Darmon
Publisher: Academic Press
ISBN: 0323139302
Category : Science
Languages : en
Pages : 306
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Book Description
Molecular Biology of the Skin: The Keratinocyte comprehensively reviews the major aspects of keratinocyte and epidermal differentiation, physiology, and pathology, primarily focusing on the molecular aspects. This exciting new resource discusses keratin genes, retinoic acid, and the use of transgenic animals in the study of dermatological pathology. The volume also highlights areas of genetic disease, new animal models to help in understanding dermatological disorders, and gene therapy using skin as a target. W.W. Franke, a pioneer in the study of the molecular biology of keratins, has written the foreword for the book.Molecular Biology of the Skin: The Keratinocyte is intended for use by dermatologists and basic researchers in cell and developmental biology. It will also be valuable for surgeons and other clinicians as well as researchers in gene therapy, virology, and pharmacology.* * Reviews keratinocyte (and epidermal) differentiation. physiology, and pathology, focusing on the molecular aspects* -Discusses keratin genes, retinoic acid, and the use of transgenic animals in the study of dermatalogical pathology* -Highlights genetic disease, new animal models, and gene therapy
Author: Michael Darmon
Publisher: Academic Press
ISBN: 0323139302
Category : Science
Languages : en
Pages : 306
Get Book Here
Book Description
Molecular Biology of the Skin: The Keratinocyte comprehensively reviews the major aspects of keratinocyte and epidermal differentiation, physiology, and pathology, primarily focusing on the molecular aspects. This exciting new resource discusses keratin genes, retinoic acid, and the use of transgenic animals in the study of dermatological pathology. The volume also highlights areas of genetic disease, new animal models to help in understanding dermatological disorders, and gene therapy using skin as a target. W.W. Franke, a pioneer in the study of the molecular biology of keratins, has written the foreword for the book.Molecular Biology of the Skin: The Keratinocyte is intended for use by dermatologists and basic researchers in cell and developmental biology. It will also be valuable for surgeons and other clinicians as well as researchers in gene therapy, virology, and pharmacology.* * Reviews keratinocyte (and epidermal) differentiation. physiology, and pathology, focusing on the molecular aspects* -Discusses keratin genes, retinoic acid, and the use of transgenic animals in the study of dermatalogical pathology* -Highlights genetic disease, new animal models, and gene therapy
Author: Georges Limbert
Publisher: Springer
ISBN: 303013279X
Category : Technology & Engineering
Languages : en
Pages : 303
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Book Description
This book presents state-of-the-art experimental and modelling techniques for skin biophysics that are currently used in academic and industrial research. It also identifies current and future challenges, as well as a growing number of opportunities in this exciting research field. The book covers the basics of skin physiology, biology, microstructural and material properties, and progressively introduces the reader to established experimental characterisation protocols and modelling approaches. Advanced topics in modelling theories and numerical implementation are also presented. The book focusses especially on: 1. Basic physiology, molecular biology, microstructural and material properties of the skin. 2. Experimental characterisation techniques for the skin (including imaging): in vivo and in vitro techniques and combination of those with in silico approaches. 3. State-of-the-art constitutive models of the skin: elastic, anelastic and mechanobiological formulations (e.g. growth, ageing, healing). 4. Applications: mechanics, damage, biological growth, healing, ageing and skin tribology. This book is addressed to postgraduate students in biomedical/mechanical/civil engineering, (bio)physics and applied mathematics, postdoctoral researchers, as well as scientists and engineers working in academia and industry engaged in skin research, particularly, if at the cross-roads of physical experiments, imaging and modelling. The book is also be of interest to clinicians/biologists who wish to learn about the possibilities offered by modern engineering techniques for skin science research and, by so doing, provide them with an incentive to broaden their outlook, engage more widely with the non-clinical research communities and, ultimately, help cross-fertilising new ideas that will lead to better treatment plans and engineering solutions.
Author: Natalia V. Botchkareva
Publisher: Humana
ISBN: 9781071606476
Category : Science
Languages : en
Pages : 0
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Book Description
This volume delivers the most important laboratory techniques that underlie dermatological investigation, including in situ, in vitro, ex vivo, and in vivo models of skin, its appendages (hair follicles, sebaceous and sweat glands), and immune cells. Also included are unique techniques that unravel epigenetic mechanisms in skin and hair follicle cells, such as gene organization in the nucleus and gene expression regulation by the non-coding transcriptome, which are important recent developments in investigative dermatology. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Molecular Dermatology: Methods and Protocols serves as an essential resource for researchers working in the areas of fundamental as well as applied dermatological science.
Author: Dr. R. K. Freinkel
Publisher: CRC Press
ISBN: 9781850700067
Category : Medical
Languages : en
Pages : 438
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Book Description
An authoritative, extensively illustrated clinician's textbook, The Biology of the Skin is written expressly for practitioners and residents in dermatology, plastic surgery, and otolaryngology. Essentially an expansion of the editors' and contributing authors' popular "Structure and Function" course given annually at the meetings of the American Academy of Dermatology, the book teaches skin biology in the context of practical clinical settings. This book covers the basic biology of the skin, how the skin functions, effects of the environment, the molecules that direct cutaneous function, genetic influences, and methods in cutaneous research. The Biology of the Skin provides a selective review of all biologic processes involving the skin and will foster an appreciation of how the skin works based on our knowledge of the basic science of skin structure and function in the 21st century.
Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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Book Description
Author: Pierre G. Agache
Publisher: Springer Science & Business Media
ISBN: 9783540017714
Category : Juvenile Nonfiction
Languages : en
Pages : 814
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Book Description
Measuring the Skin presents all techniques devoted to non-invasive normal or diseased skin measurement. As opposed other books, this text embraces old and new validated techniques for all skin suborgans and functions. The book is ideal as a small encyclopedia since it provides the answer to any question concerning skin measurement. Each technique is discussed to help select the most appropriate one for each special case. Another novel feature is that the book bases the skin investigation on the physiology and anatomy. Each chapter is preceded by a compendium of current knowledge on the structure or function dealt with. The book may also be used as a research tool. It contains a novel, and presently unique list of more than 400 physical and biological skin constants, which are all referenced.
Author: Centre international de recherche sur le cancer
Publisher: International Agency for Research on Cancer
ISBN: 9789283224402
Category : Medical
Languages : en
Pages : 0
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Book Description
The WHO Classification of Skin Tumours is the 11th volume in the 4th edition of the WHO series on the classification of human tumours. The series (also known as the Blue Books) has long been regarded by pathologists as the gold standard for the diagnosis of tumours, and it is an indispensable guide for the design of evaluations, clinical trials, and studies involving cancer. These authoritative and concise reference books provide an international standard for anyone involved in cancer research or the care of cancer patients. Diagnostic criteria, pathological features, and genetic and other associated molecular alterations are described in a disease-oriented manner. This volume updates the existing ICD-O codes and provides new codes for use in epidemiology and cancer registration. It also provides information on clinical features, pathology, genetics, prognosis, and protective factors for each of the tumour types covered. The editors expect that this volume will be of particular interest to pathologists, oncologists, and dermatologists who manage or research skin tumours. Sections are included on all recognized neoplasms (and their variants) of the skin and its adnexae. Since the previous edition, there have been particularly substantial changes to the classification of melanoma, based on the latest information from genetic and molecular studies.
Author: R.A.F. Clark
Publisher: Springer Science & Business Media
ISBN: 148990185X
Category : Science
Languages : en
Pages : 624
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Book Description
'Provides comprehensive detail on the various aspects of particular molecules involved in the phases of injury and repair and the cellular movements and processes....This is an excellent reference book for libraries serving biology and health science clientele and for workers in this field of research.' -American Scientist, from a review of the First Edition All chapters of this second edition have been completely revised and expanded-especially the chapters on growth factors and extracellular matrix molecules. New chapters discuss provisional matrix proteins, extracellular matrix receptors, and scarring versus nonscarring wound healing.
Author: Mohammad Albanna
Publisher: Academic Press
ISBN: 012801797X
Category : Technology & Engineering
Languages : en
Pages : 468
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Book Description
The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. From burn victims to surgical scars and plastic surgery, the therapies resulting from skin tissue engineering and regenerative medicine are important to a broad spectrum of patients. Skin Tissue Engineering and Regenerative Medicine provides a translational link for biomedical researchers across fields to understand the inter-disciplinary approaches which expanded available therapies for patients and additional research collaboration. This work expands on the primary literature on the state of the art of cell therapies and biomaterials to review the most widely used surgical therapies for the specific clinical scenarios. - Explores cellular and molecular processes of wound healing, scar formation, and dermal repair - Includes examples of animal models for wound healing and translation to the clinical world - Presents the current state of, and clinical opportunities for, extracellular matrices, natural biomaterials, synthetic biomaterials, biologic skin substitutes, and adult and fetal stem and skin cells for skin regenerative therapies and wound management - Discusses new innovative approaches for wound healing including skin bioprinting and directed cellular therapies
Author: Nina G. Jablonski
Publisher: Univ of California Press
ISBN: 0520283864
Category : Science
Languages : en
Pages : 280
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Book Description
This book investigates the social history of skin color from prehistory to the present, showing how our body's most visible trait influences our social interactions in profound and complex ways. The author begins with the biology and evolution of skin pigmentation, explaining how skin color changed as humans moved around the globe. She explores the relationship between melanin pigment and sunlight, and examines the consequences of rapid migrations, vacations, and other lifestyle choices that can create mismatches between our skin color and our environment. Richly illustrated, this book explains why skin color has come to be a biological trait with great social meaning-- a product of evolution perceived by culture. It considers how we form impressions of others, how we create and use stereotypes, how negative stereotypes about dark skin developed and have played out through history. Offering examples of how attitudes about skin color differ in the U.S., Brazil, India, and South Africa, the author suggests that a knowledge of the evolution and social importance of skin color can help eliminate color-based discrimination and racism.
