Molecular and Functional Insights Into the Pulmonary Vasculature PDF Download
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Author: Kaushik Parthasarathi
Publisher: Springer
ISBN: 3319684833
Category : Medical
Languages : en
Pages : 90
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Book Description
This book provides a comprehensive review of the structure, function and pathophysiology of the pulmonary vasculature. Emerging evidence reveals the multifaceted roles played by the pulmonary vasculature. To reflect those roles, the individual chapters address topics ranging from pulmonary blood vessel development to vascular endothelial apoptosis, and delve deeply into our current understanding of various aspects of the pulmonary vasculature.
Author: Kaushik Parthasarathi
Publisher: Springer
ISBN: 3319684833
Category : Medical
Languages : en
Pages : 90
Get Book Here
Book Description
This book provides a comprehensive review of the structure, function and pathophysiology of the pulmonary vasculature. Emerging evidence reveals the multifaceted roles played by the pulmonary vasculature. To reflect those roles, the individual chapters address topics ranging from pulmonary blood vessel development to vascular endothelial apoptosis, and delve deeply into our current understanding of various aspects of the pulmonary vasculature.
Author: Toshio Nakanishi
Publisher: Springer Nature
ISBN: 9811511853
Category : Medical
Languages : en
Pages : 374
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Book Description
This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.
Author: Alan H. Jobe
Publisher: Cambridge University Press
ISBN: 1316665178
Category : Medical
Languages : en
Pages :
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Book Description
Lung disease affects more than 600 million people worldwide. While some of these lung diseases have an obvious developmental component, there is growing appreciation that processes and pathways critical for normal lung development are also important for postnatal tissue homeostasis and are dysregulated in lung disease. This book provides an authoritative review of fetal and neonatal lung development and is designed to provide a diverse group of scientists, spanning the basic to clinical research spectrum, with the latest developments on the cellular and molecular mechanisms of normal lung development and injury-repair processes, and how they are dysregulated in disease. The book covers genetics, omics, and systems biology as well as new imaging techniques that are transforming studies of lung development. The reader will learn where the field of lung development has been, where it is presently, and where it is going in order to improve outcomes for patients with common and rare lung diseases.
Author: Hans-Ulrich Kauczor
Publisher: Springer
ISBN: 3319426176
Category : Medical
Languages : en
Pages : 519
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Book Description
This book provides a comprehensive overview of how to use MRI for the imaging of lung disease. Special emphasis is placed on routine applications and the clinical impact of MRI in each setting. In addition, current technological developments are reviewed and information presented on dedicated applications of MRI in preclinical and translational research, clinical trials, and specialized institutions. During the past two decades, significant advances in the technology have enabled MRI to enter and mature in the clinical arena of chest imaging. Standard protocols are now readily available on MR scanners, and MRI is recommended as the first- or second-line imaging modality for a variety of lung diseases, not limited to cystic fibrosis, pulmonary hypertension, and lung cancer. The benefits and added value of MRI originate from its ability to both visualize lung structure and provide information on different aspects of lung function, such as perfusion, respiratory motion, ventilation, and gas exchange. On this basis, novel quantitative surrogates for lung function and therapy control (imaging biomarkers) are generated. The second edition of MRI of the Lung has been fully updated to take account of recent advances. It is written by an internationally balanced team of renowned authors representing all major groups in the field.
Author: Robert P. Baughman
Publisher: Springer Science & Business Media
ISBN: 1603270744
Category : Medical
Languages : en
Pages : 255
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Book Description
Interstitial lung disease (ILD) is a broad category of lung diseases that includes more than 150 disorders characterized by scarring or fibrosis of the lungs. In Pulmonary Arterial Hypertension and Interstitial Lung Disease: A Clinical Guide, renowned experts provide a state-of-the-art overview of the problems seen by physicians in the clinical management of ILDs. Divided into two sections, the first part provides and update on general issues and introduces both interstitial lung disease and associated pulmonary hypertension. A detailed analysis of the pathology of the various interstitial lung diseases is also provided. The second part addresses specific categories of disease. Bronchiolitis, hypersensitivity pneumonitis, and other conditions are covered, and the use of inspiratory and expiratory high resolution CT scan is discussed as well. This important new text is an invaluable resource for the practicing physician who must be aware of the broad and troubling manifestations of interstitial lung disease.
Author: Sean P. Gaine
Publisher: Springer
ISBN: 1447123980
Category : Medical
Languages : en
Pages : 326
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Book Description
The heart and lung are intricately linked. When the heart is affected by disease, the lungs will often show some related pathological or clinical conditions and vice versa. Pulmonary heart disease is by definition a condition when the lungs cause the heart to fail. The left ventricle in combination with the other structures in the “left heart” pumps blood throughout the body. The right ventricle (and structures of the “right heart”) pumps blood to the lungs where it is oxygenated and returned to the left heart for distribution. In normal circumstances, the right heart pumps blood into the lungs without any resistance. The lungs usually have minimal pressure and the right heart easily pumps blood through. However when there is lung disease present, like emphysema, chronic obstructive lung disease (COPD) or pulmonary hypertension- the small blood vessels become very stiff and rigid. The right ventricle is no longer able to push blood into the lungs and eventually fails. This is known as pulmonary heart disease. Pulmonary heart disease is also known as right heart failure or cor pulmonale. The chief cause of right heart failure is the increase in blood pressure in the lungs (pulmonary artery).
Author: Jason X. -J. Yuan
Publisher: Springer Science & Business Media
ISBN: 0387874291
Category : Medical
Languages : en
Pages : 1640
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Book Description
Textbook of Pulmonary Vascular Diseases combines basic scientific knowledge on the pulmonary circulatory system at levels of the molecule, cell, tissue, and organ with clinical diagnosis and treatment of pulmonary vascular diseases. State-of-the-art techniques and their potential applications in research, diagnosis, and treatment of pulmonary vascular diseases are also covered.
Author: John N. Maina
Publisher: Springer Nature
ISBN: 3031351800
Category : Science
Languages : en
Pages : 391
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Book Description
Birds have and continue to fascinate scientists and the general public. While the avian respiratory system has unremittingly been investigated for nearly five centuries, important aspects on its biology remain cryptic and controversial. In this book, resolving some of the contentious issues, developmental-, structural- and functional aspects of the avian lung-air sac system are particularized: it endeavors to answer following fundamental questions on the biology of birds: how, when and why did birds become what they are? Flight is a unique form of locomotion. It considerably shaped the form and the essence of birds as animals. An exceptionally efficient respiratory system capacitated birds to procure the exceptionally large quantities of oxygen needed for powered (active) flight. Among the extant air-breathing vertebrates, comprising ~11,000 species, birds are the most species-rich-, numerically abundant- and extensively distributed animal taxon. After realizing volancy, they easily overcame geographical obstacles and extensively dispersed into various ecological niches where they underwent remarkable adaptive radiation. While the external morphology of birds is inconceivably uniform for such a considerably speciose taxon, contingent on among other attributes, lifestyle, habitat and phylogenetic level of development have foremost determined the novelties that are displayed by diverse species of birds. Here, critical synthesizes of the most recent findings with the historical ones, evolution and behavior and development, structure and function of the exceptionally elaborate respiratory system of birds are detailed. The prominence of modern birds as a taxon in the Animal Kingdom is underscored. The book should appeal to researchers who are interested in evolutionary processes and how adaptive specializations correlate with biological physiognomies and exigencies, comparative biologists who focus on how various animals have solved respiratory pressures, people who study respiration in birds and other animals and ornithologists who love and enjoy birds for what they are – profoundly interesting animals.
Author: N. Radhakrishnan
Publisher: Academic Press
ISBN: 0323884342
Category : Science
Languages : en
Pages : 520
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Book Description
Genesis, Pathophysiology Management of Venous Diseases is the must-have resource on venous disease. The book bridges the gap between basic science and clinical medicine, covering the history of venous surgery, the lymphatic system and anatomy, pathophysiology of various venous disease, etiology, clinical manifestations and diagnosis, management, and medical and surgical treatment options. It also places attention on genetic studies and pharmacological analysis of various anticoagulants which are widely used in treating venous diseases and deep vein thrombosis and highlights the importance of microscopic venous valves and their pathology in both normal and disease condition. The breadth of topics covered makes this reference suitable for a range of professionals in phlebolymphology and cardiology, including medical students, practicing clinicians, surgeons, researchers, radiologists, bioengineers, and more. - Provides complete, up-to-date developments in the field of phlebolymphology, including the history of venous surgery, lymphatic system and anatomy, pathophysiology of various venous disease, and more - Includes new etiological and pathophysiological concepts and the latest outlooks and trends in the management of CVD - Written in an easy-to-read manner, the book includes tables, figures, clinical photographs and medical illustrations to aid understanding
Author: Hugh D. Allen
Publisher: Lippincott Williams & Wilkins
ISBN: 1451171277
Category : Medical
Languages : en
Pages : 1757
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Book Description
This 8th Edition of Moss and Adams' Heart Disease in Infants, Children, and Adolescents: Including the Fetus and Young Adult, provides updated and useful information from leading experts in pediatric cardiology. Added chapters and a companion web site that includes the full text with bonus question and answer sections make this Moss and Adams’ edition a valuable resource for those who care for infants, children, adolescents, young adults, and fetuses with heart disease. Features: · Access to online questions similar to those on the pediatric cardiology board examination to prepare you for certification or recertification · Leading international experts provide state-of-the-art diagnostic and interventional techniques to keep you abreast of the latest advances in treatment of young patients · Chapters on quality of life, quality and safety, pharmacology, and research design add to this well-respected text
