Modern Aldol Reactions, 2 Volume Set PDF Download
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Author: Rainer Mahrwald
Publisher: John Wiley & Sons
ISBN: 3527307141
Category : Science
Languages : en
Pages : 759
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Book Description
At long last, the complete spectrum of the aldol reaction is presented here in this two-volume handbook. Top authors guarantee contributions of the highest quality, beginning with fundamentals and then moving on to enolates and catalytic aldol reactions, including the Mukaiyama Reaction. Further sections are devoted to enzymatic aldol reactions in synthesis as well as such related reactions as the Henry, Ene and Aldol-Tishchenko reactions. The wealth of information contained here allows a comprehensive overview of this important topic in organic chemistry, removing the need for the hitherto time-consuming research among the widely dispersed literature. With a foreword by Professor D. A. Evans.
Author: Rainer Mahrwald
Publisher: John Wiley & Sons
ISBN: 3527307141
Category : Science
Languages : en
Pages : 759
Get Book Here
Book Description
At long last, the complete spectrum of the aldol reaction is presented here in this two-volume handbook. Top authors guarantee contributions of the highest quality, beginning with fundamentals and then moving on to enolates and catalytic aldol reactions, including the Mukaiyama Reaction. Further sections are devoted to enzymatic aldol reactions in synthesis as well as such related reactions as the Henry, Ene and Aldol-Tishchenko reactions. The wealth of information contained here allows a comprehensive overview of this important topic in organic chemistry, removing the need for the hitherto time-consuming research among the widely dispersed literature. With a foreword by Professor D. A. Evans.
Author: Karlheinz Drauz
Publisher: John Wiley & Sons
ISBN: 3527325476
Category : Science
Languages : en
Pages : 2143
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Book Description
This comprehensive three-volume set is the standard reference in the field of organic synthesis, catalysis and biocatalysis. Edited by a highly experienced and highly knowledgeable team with a tremendous amount of experience in this field and its applications, this edition retains the successful concept of past editions, while the contents are very much focused on new developments in the field. All the techniques described are directly transferable from the lab to the industrial scale, making for a very application-oriented approach. A must for all chemists and biotechnologists.
Author: Jacek Wojaczynski
Publisher: John Wiley & Sons
ISBN: 3527834192
Category : Science
Languages : en
Pages : 692
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Book Description
Chiral Building Blocks in Asymmetric Synthesis A comprehensive introduction to the important classes of chiral building blocks Chirality — the asymmetric quality found in certain chemical compounds — plays an essential role in our world: chiral compounds can be found in biology, pharmaceutical compounds, agrochemicals, and fragrances. The stereoselective preparation of these complex molecular constructions constitutes a challenge. To this end, modern asymmetric synthesis utilizes a variety of valuable and efficient reagents employed as chiral auxiliaries, metal complexes and organocatalysts in stereoselective catalysis, and enantiopure reactants termed as chiral building blocks. In Chiral Building Blocks in Asymmetric Synthesis, the achievements in the fields of preparation of and applications of chiral blocks are presented. In doing so, the book comprehensively discusses the important classes of these reactants as the key for the asymmetric synthesis of chiral molecules. As such, it is an indispensable resource about synthetic methods, as well as possible modifications and transformations of important classes of chiral compounds. It also highlights the importance of their use as reactants and auxiliaries in the preparation of more sophisticated molecules or supramolecular systems. In Chiral Building Blocks in Asymmetric Synthesis readers will also find: Organization according to the most important compound classes — e.g. amino acids, BINOL and its derivatives, terpenes, and others — with an emphasis on synthesis and application A focus on the use of chiral building blocks for the preparation of bioactive compounds and supramolecular assemblies Chiral Building Blocks in Asymmetric Synthesis is a useful reference for organic chemists, catalytic chemists, chemists in industry, medicinal chemists, pharmaceutical chemists, and the libraries that support them.
Author: Chao-Jun Li
Publisher: John Wiley & Sons
ISBN: 3527342818
Category : Science
Languages : en
Pages : 848
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Book Description
Dieses Fachbuch untersucht systematisch die Leistungsfähigkeit der Silberkatalyse, behandelt neu entwickelte organische Reaktionen und den Reaktionsmechanismus. Der Schwerpunkt liegt auf den Eigenschaften und dem Vergleich der Vorteile diese Katalyse in der organischen Synthese.
Author: Michael B. Smith
Publisher: John Wiley & Sons
ISBN: 1119371791
Category : Science
Languages : en
Pages : 4728
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Book Description
The completely revised and updated, definitive resource for students and professionals in organic chemistry The revised and updated 8th edition of March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure explains the theories of organic chemistry with examples and reactions. This book is the most comprehensive resource about organic chemistry available. Readers are guided on the planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions The opening chapters of March's Advanced Organic Chemistry, 8th Edition deal with the structure of organic compounds and discuss important organic chemistry bonds, fundamental principles of conformation, and stereochemistry of organic molecules, and reactive intermediates in organic chemistry. Further coverage concerns general principles of mechanism in organic chemistry, including acids and bases, photochemistry, sonochemistry and microwave irradiation. The relationship between structure and reactivity is also covered. The final chapters cover the nature and scope of organic reactions and their mechanisms. This edition: Provides revised examples and citations that reflect advances in areas of organic chemistry published between 2011 and 2017 Includes appendices on the literature of organic chemistry and the classification of reactions according to the compounds prepared Instructs the reader on preparing and conducting multi-step synthetic reactions, and provides complete descriptions of each reaction The 8th edition of March's Advanced Organic Chemistry proves once again that it is a must-have desktop reference and textbook for every student and professional working in organic chemistry or related fields. Winner of the Textbook & Acadmic Authors Association 2021 McGuffey Longevity Award.
Author: Jacob Zabicky
Publisher: John Wiley & Sons
ISBN: 9780470743416
Category : Science
Languages : en
Pages : 1250
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Book Description
Metal Enolates form a class of compounds that have recently received much study because of their part in the important C-C-bond forming aldol reaction. Focusing on this important class of compounds in organic synthesis, The Chemistry of Metal Enolates features contributions on all aspects of Metal Enolate chemistry from the world?s leading experts. Delivering the exceptional quality that?s expected from the Patai Series, this text is essential reading for organic chemists.
Author: Edwin Vedejs
Publisher: John Wiley & Sons
ISBN: 3527336184
Category : Science
Languages : en
Pages : 1476
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Book Description
This three-volume set represents the first comprehensive coverage of the rapidly expanding field of Lewis base catalysis that has attracted enormous attention in recent years. Lewis base catalysis is a conceptually novel paradigm that encompasses an extremely wide variety of preparatively useful transformations and is particularly effective for enantioselectively constructing new stereogenic centers. As electron-pair donors, Lewis bases can influence the rate and stereochemical course of myriad synthetic organic reactions. The book presents the conceptual/mechanistic principles that underlie Lewis base catalysis, and then builds upon that foundation with a thorough presentation of many different reaction types. And last but not least, the editors, Prof. Edwin Vedejs and Prof. Scott E. Denmark, are without doubt the leaders in this emerging field and have compiled high quality contributions from an impressive collection of international experts.
Author: Gerald Dyker
Publisher: Wiley-VCH
ISBN:
Category : Science
Languages : en
Pages : 352
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Book Description
Here, the whole range of the functionalization of CH-bonds is presented for the first time in one handbook, with the focus throughout on topicality and practicability. Topics span modern catalysts for Friedel-Crafts type reactions to transition metal catalysts for the oxofunctionalization, via new methods for radicalic halogenation to domino processes by catalytic ortho metalation. Renowned for his research as well as for his excellent articles and reviews, Gerald Dyker provides in these two volumes reliable and typical experimental procedures, thus lending the book great practical value.
Author: Norbert Krause
Publisher: Wiley-VCH
ISBN:
Category : Science
Languages : en
Pages : 616
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Book Description
In this two-volume handbook, the editors Norbert Krause and A. Stephen K. Hashmi present all the important aspects and facts related to this hot topic. The treatment covers the whole range from the synthesis and classification via reactions right up to possible applications in the synthesis of natural products and drugs. With their excellent contributions an international team of outstanding authors highlight the multifarious uses and classes of allenes, making this an indispensable work for every organic chemist. From the Table of Contents: SYNTHESIS OF ALLENES Synthesis of Allenes by Isomerization Reactions Metal-Mediated Synthesis of Allenes Transition-Metal-Catalyzed Synthesis of Allenes Enantioselective Synthesis of Allenes SPECIAL CLASSES OF ALLENES Allenic Hydrocarbons - Preparation and Use in Organic Synthesis Cyclic Allenes Acceptor-Substituted Allenes Donor-Substituted Allenes Synthesis and Reactions of Allenylmetal Reagents REACTIONS OF ALLENES Ionic Additions to Allenes Fundamentals and Application of Free Radical Addition to Allenes Cycloadditions of Allenes Cyclizations of Allenes Transitions-Metal-Catalyzed Cross Couplings of Allenes Transitions-Metal-Catalyzed Cycloisomerizations of Allenes Transition-Metal-Catalyzed Addition/Cycloadditions of Allenes Oxidation of Allenes APPLICATIONS Allenic Natural Products and Phamaceuticals Allenes in Natural Product Synthesis Enyne-Allenes
Author: Alexandre Alexakis
Publisher: John Wiley & Sons
ISBN: 3527664599
Category : Science
Languages : en
Pages : 467
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Book Description
This book reflects the increasing interest among the chemical synthetic community in the area of asymmetric copper-catalyzed reactions, and introduces readers to the latest, most significant developments in the field. The contents are organized according to reaction type and cover mechanistic and spectroscopic aspects as well as applications in the synthesis of natural products. A whole chapter is devoted to understanding how primary organometallics interact with copper to provide selective catalysts for allylic substitution and conjugate addition, both of which are treated in separate chapters. Another is devoted to the variety of substrates and experimental protocols, while an entire chapter covers the use on non-carbon nucleophiles. Other chapters deal with less-known reactions, such as carbometallation or the additions to imines and related systems, while the more established reactions cyclopropanation and aziridination as well as the use of copper (II) Lewis acids are warranted their own special chapters. Two further chapters concern the processes involved, as determined by mechanistic studies. Finally, a whole chapter is devoted to the synthetic applications. This is essential reading for researchers at academic institutions and professionals at pharmaceutical or agrochemical companies.
