Modeling of Electrophysiology and Tension Development in the Human Heart PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Modeling of Electrophysiology and Tension Development in the Human Heart PDF full book. Access full book title Modeling of Electrophysiology and Tension Development in the Human Heart by Gunnar Seemann. Download full books in PDF and EPUB format.
Author: Gunnar Seemann
Publisher:
ISBN: 9783937300665
Category :
Languages : en
Pages : 233
Get Book Here
Book Description
Author: Gunnar Seemann
Publisher:
ISBN: 9783937300665
Category :
Languages : en
Pages : 233
Get Book Here
Book Description
Author:
Publisher:
ISBN:
Category :
Languages : de
Pages : 0
Get Book Here
Book Description
Comprehension of the beating of the human heart is important for cardiac research and will improve many clinical applications. Simulations based on models describing cardiac electro-mechanics can acquire insights into this behavior. This work focuses on the mathematical reconstruction of electrophysiology, excitation conduction, and tension development in the human heart on the cellular and the tissue level. The tissue models represent accurate anatomical shapes of the atria and the ventricles and incorporate electrophysiological heterogeneity and anisotropic conduction. The simulations comprehend the physiological behavior of the ventricles and of the atrium including the sinoatrial node as well as pathological cases like ventricular and atrial fibrillation and genetic defects in ionic channels.
Author: Frank B. Sachse
Publisher: Springer
ISBN: 3540259260
Category : Medical
Languages : en
Pages : 364
Get Book Here
Book Description
This book is devoted to computer-based modeling in cardiology, by taking an educational point of view, and by summarizing knowledge from several, commonly considered delimited areas of cardiac research in a consistent way. First, the foundations and numerical techniques from mathematics are provided, with a particular focus on the finite element and finite differences methods. Then, the theory of electric fields and continuum mechanics is introduced with respect to numerical calculations in anisotropic biological media. In addition to the presentation of digital image processing techniques, the following chapters deal with particular aspects of cardiac modeling: cardiac anatomy, cardiac electro physiology, cardiac mechanics, modeling of cardiac electro mechanics. This book was written for researchers in modeling and cardiology, for clinical cardiologists, and for advanced students.
Author: Loewe, Axel
Publisher: KIT Scientific Publishing
ISBN: 3731505282
Category : Technology (General)
Languages : en
Pages : 342
Get Book Here
Book Description
Half of the patients suffering from atrial fibrillation (AF) cannot be treated adequately, today. This book presents multi-scale computational methods to advance our understanding of patho-mechanisms, to improve the diagnosis of patients harboring an arrhythmogenic substrate, and to tailor therapy. The modeling pipeline ranges from ion channels on the subcellular level up to the ECG on the body surface. The tailored therapeutic approaches carry the potential to reduce the burden of AF.
Author: Daniel C. Sigg
Publisher: Springer Science & Business Media
ISBN: 1441966587
Category : Medical
Languages : en
Pages : 490
Get Book Here
Book Description
Cardiovascular disease is the major cause of mortality and morbidity in the Western Hemisphere. While significant progress has been made in treating a major sub-category of cardiac disease, arrhythmias, significant unmet needs remain. In particular, every day, thousands of patients die because of arrhythmias in the US alone, and atrial fibrillation is the most common arrhythmia affecting millions of patients in the US alone at a given time. Therefore, there is a public need to continue to develop new and better therapies for arrhythmias. Accordingly, an ever increasing number of biomedical, pharmaceutical, and medical personnel is interested in studying various aspects of arrhythmias at a basic, translational, and applied level, both in industry (ie Biotech, Pharmaceutical and device), and in academia. Not only has our overall understanding of molecular bases of disease dramatically increased, but so has the number of available and emerging molecular, pharmacological or device treatment based therapies. This practical, state-of-the art handbook will summarize and review key research methods and protocols, their advantages and pitfalls, with a focus on practical implementation, and collaborative cross-functional research. The volume will include visual and easy-to-use graphics, bulleted summaries, boxed summary paragraphs, links to reference websites, equipment manufacturers where appropriate, photographs of typical experimental setups and so forth, to keep this book very focused on practical methods and implementation, and yet, provide enough theory that the principles are clearly understood and can be easily applied.
Author: Mathias Wilhelms
Publisher: KIT Scientific Publishing
ISBN: 3731500450
Category : Technology & Engineering
Languages : en
Pages : 206
Get Book Here
Book Description
Multiscale modeling of cardiac electrophysiology helps to better understand the underlying mechanisms of atrial fibrillation, acute cardiac ischemia and pharmacological treatment. For this purpose, measurement data reflecting these conditions have to be integrated into models of cardiac electrophysiology. Several methods for this model adaptation are introduced in this thesis. The resulting effects are investigated in multiscale simulations ranging from the ion channel up to the body surface.AbstractEnglisch = Multiscale modeling of cardiac electrophysiology helps to better understand the underlying mechanisms of atrial fibrillation, acute cardiac ischemia and pharmacological treatment. For this purpose, measurement data reflecting these conditions have to be integrated into models of cardiac electrophysiology. Several methods for this model adaptation are introduced in this thesis. The resulting effects are investigated in multiscale simulations ranging from the ion channel up to the body surface.
Author: David Urs Josef Keller
Publisher: KIT Scientific Publishing
ISBN: 3866447140
Category : Technology & Engineering
Languages : en
Pages : 278
Get Book Here
Book Description
This work is focused on different aspects within the loop of multiscale modeling: On the cellular level, effects of adrenergic regulation and the Long-QT syndrome have been investigated.On the organ level, a model for the excitation conduction system was developed and the role of electrophysiological heterogeneities was analyzed.On the torso level a dynamic model of a deforming heart was created and the effects of tissue conductivities on the solution of the forward problem were evaluated
Author: Alejandro F. Frangi
Publisher: Springer Science & Business Media
ISBN: 3540261613
Category : Computers
Languages : en
Pages : 503
Get Book Here
Book Description
This book constitutes the refereed proceedings of the Third International Workshop on Functional Imaging and Modeling of the Heart, FIMH 2005, held in Barcelona, Spain in June 2005. The 47 revised full papers presented were carefully reviewed and selected from numerous submissions. The papers are organized in topical sections on modeling of the heart: anatomy extraction and description; electro-physiology and electro- and magnetography; modeling of the cardiac mechanisms and functions; and cardiac motion estimation.
Author: Boris Ja. Kogan
Publisher: Springer Science & Business Media
ISBN: 0387766863
Category : Computers
Languages : en
Pages : 236
Get Book Here
Book Description
Introduction to Computational Cardiology provides a comprehensive, in-depth treatment of the fundamental concepts and research challenges involved in the mathematical modeling and computer simulation of dynamical processes in the heart, under normal and pathological conditions. About this textbook: - Presents descriptions of models used in both biology and medicine for discovering the mechanisms of heart function and dysfunction on several physiological scales across different species. - Provides several examples throughout the textbook and exercises at the end which facilitate understanding of basic concepts and introduces, for implementation, treated problems to parallel supercomputers. Introduction to Computational Cardiology serves as a secondary textbook or reference book for advanced-level students in computer science, electrical engineering, biomedical engineering, and cardiac electrophysiology. It is also suitable for researchers employing mathematical modeling and computer simulations of biomedical problems.
Author: Oussama Jarrousse
Publisher: KIT Scientific Publishing
ISBN: 3866447426
Category : Technology & Engineering
Languages : en
Pages : 244
Get Book Here
Book Description
Mass-spring systems are considered the simplest and most intuitive of all deformable models. They are computationally efficient, and can handle large deformations with ease. But they suffer several intrinsic limitations. In this book a modified mass-spring system for physically based deformation modeling that addresses the limitations and solves them elegantly is presented. Several implementations in modeling breast mechanics, heart mechanics and for elastic images registration are presented.
