Methods for Computational Population Dynamics

Methods for Computational Population Dynamics PDF Author: Bruce P. Ayati
Publisher:
ISBN:
Category : Boundary value problems
Languages : en
Pages : 126

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Book Description

Methods for Computational Population Dynamics

Methods for Computational Population Dynamics PDF Author: Bruce P. Ayati
Publisher:
ISBN:
Category : Boundary value problems
Languages : en
Pages : 126

Get Book Here

Book Description


Computational And Mathematical Population Dynamics

Computational And Mathematical Population Dynamics PDF Author: Necibe Tuncer
Publisher: World Scientific
ISBN: 9811263043
Category : Mathematics
Languages : en
Pages : 470

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Book Description
This book is a collection of works that represent the recent advancements in computational and mathematical methods applied to population dynamics. It concentrates on both development of new tools as well as on innovative use of existing tools to obtain new understanding of biological systems. The volume introduces new state-of-the-art techniques for defining and solving numerically control problems in mathematical biology in which the control appears linearly. Such problems produce simpler optimal controls that can be implemented in practice. The book further develops tools for fitting multi-scale models to multi-scale data and studying the practical identifiability of the parameters from multi-scale data. Novel model of Zika with Wolbahia infection in mosquitoes suggests that the most suitable control strategy to control Zika in the absence of Wolbahia is killing mosquitoes but the most suitable strategy when mosquitoes are Wolbahia infected is the treatment of humans.A completely novel methodology of developing discrete-continuous hybrid models of multi-species interactions is also introduced together with avantgarde techniques for discrete-continuous hybrid models analysis. A mathematical model leads to new observations of the within-host virus dynamics and its interplay with the immune responses. In particular, it is observed that the parameters promoting CTL responses need to be boosted over parameters promoting antibody production to obtain a biologically relevant steady state. A novel stochastic model of COVID-19 investigates quarantine and lock down as important strategies for control and elimination of COVID-19.

Microsimulation and Population Dynamics

Microsimulation and Population Dynamics PDF Author: Alain Bélanger
Publisher: Springer
ISBN: 3319446630
Category : Social Science
Languages : en
Pages : 206

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Book Description
This book is a practical, step-by-step introduction to microsimulation in demography. It shows how to use Modgen, a powerful and free microsimulation platform built by Statistics Canada. The authors' hands-on explanation of model development will help readers make their own. The book teaches how to create and run a simple cohort model with a single fixed-rate event, and builds upon this concept. It introduces how to develop both a single state life table as well as a multiple increment-decrement life table using the tools provided by Modgen. The authors illustrate how to easily upgrade an existing model by adding new modules and new dimensions as determinants of a risk already modeled. The integration of a fertility module and a base population allows the user to bring new actors into the simulation and transform a cohort-based model into a population-based one. The final addition of an international migration module allows the user to accomplish fully open, multi-regional projections. This accessible introduction will be of interest to researchers and students in population studies and other social sciences. It will also appeal to anyone interested in the computational modeling of population dynamics.

Data-driven Modelling of Structured Populations

Data-driven Modelling of Structured Populations PDF Author: Stephen P. Ellner
Publisher: Springer
ISBN: 3319288938
Category : Mathematics
Languages : en
Pages : 339

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Book Description
This book is a “How To” guide for modeling population dynamics using Integral Projection Models (IPM) starting from observational data. It is written by a leading research team in this area and includes code in the R language (in the text and online) to carry out all computations. The intended audience are ecologists, evolutionary biologists, and mathematical biologists interested in developing data-driven models for animal and plant populations. IPMs may seem hard as they involve integrals. The aim of this book is to demystify IPMs, so they become the model of choice for populations structured by size or other continuously varying traits. The book uses real examples of increasing complexity to show how the life-cycle of the study organism naturally leads to the appropriate statistical analysis, which leads directly to the IPM itself. A wide range of model types and analyses are presented, including model construction, computational methods, and the underlying theory, with the more technical material in Boxes and Appendices. Self-contained R code which replicates all of the figures and calculations within the text is available to readers on GitHub. Stephen P. Ellner is Horace White Professor of Ecology and Evolutionary Biology at Cornell University, USA; Dylan Z. Childs is Lecturer and NERC Postdoctoral Fellow in the Department of Animal and Plant Sciences at The University of Sheffield, UK; Mark Rees is Professor in the Department of Animal and Plant Sciences at The University of Sheffield, UK.

Mathematical Modeling and Computational Methods for Structured Populations

Mathematical Modeling and Computational Methods for Structured Populations PDF Author: Mingtao Xia
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

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Book Description
Structured population models are fundamental in the fields of biology, ecology, and social sciences, as they provide both theoretical insights and practical applications. Different structured population models range from modeling cellular population proliferation and population dynamics to simulating disease spread on social networks. However, there has been little work on modeling populations across different scales that could link individual behavior to population dynamics. Additionally, for existing mathematical models on structured populations, several computational challenges arise as how to develop efficient numerical solvers to simulate those models and to control the dynamics of those models. Overall, my dissertation covers three related topics: modeling structured populations, developing efficient numerical solvers to simulate these models, and developing control algorithms to control population dynamics. Specifically, my dissertation focuses on modeling and devising algorithms for two types of structured populations: i) age, size, or added size-structured cell population for describing cellular proliferation and ii) the structured infected-time- or number-of-contact-based human population for describing disease spread. Regarding the structured cellular population, we derive mathematical models at both the macroscopic population dynamics level and microscopic individual behavior level, leading to structured partial differential equation (PDE) models for cellular proliferation with different structure variables such as cellular age, size, or added size. Next, we develop an efficient adaptive spectral method for numerically solving spatiotemporal PDEs, which was inspired by simulating the blowup behavior in the unbounded-domain PDE model for cellular populations. In addition to the structured population models, the adaptive spectral method proves efficient and accurate in solving a wide range of spatiotemporal PDEs in unbounded domains such as the Schr dinger equations in quantum mechanics. Regarding the structured human population, we introduce an infected-time-structured PDE model and a number-of-contact-structured ODE model for simulating disease spread, e.g., COVID-19, in the population. Then, for the number-of-contact-structured ODE model, we develop classic Pontryagin-maximum-principle-based and reinforcement-learning-based optimal control algorithms. These two algorithms can effectively mitigate the spread of disease by appropriately allocating limited test kits or vaccination resources.

Population Dynamics in Variable Environments

Population Dynamics in Variable Environments PDF Author: Shripad Tuljapurkar
Publisher: Springer Science & Business Media
ISBN: 3642516521
Category : Mathematics
Languages : en
Pages : 148

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Book Description
Demography relates observable facts about individuals to the dynamics of populations. If the dynamics are linear and do not change over time, the classical theory of Lotka (1907) and Leslie (1945) is the central tool of demography. This book addresses the situation when the assumption of constancy is dropped. In many practical situations, a population will display unpredictable variation over time in its vital rates, which must then be described in statistical terms. Most of this book is concerned with the theory of populations which are subject to random temporal changes in their vital rates, although other kinds of variation (e. g. , cyclical) are also dealt with. The central questions are: how does temporal variation work its way into a population's future, and how does it affect our interpretation of a population's past. The results here are directed at demographers of humans and at popula tion biologists. The uneven mathematical level is dictated by the material, but the book should be accessible to readers interested in population the ory. (Readers looking for background or prerequisites will find much of it in Hal Caswell's Matrix population models: construction, analysis, and in terpretation (Sinauer 1989) ). This book is in essence a progress report and is deliberately brief; I hope that it is not mystifying. I have not attempted to be complete about either the history or the subject, although most sig nificant results and methods are presented.

The Basic Approach to Age-Structured Population Dynamics

The Basic Approach to Age-Structured Population Dynamics PDF Author: Mimmo Iannelli
Publisher: Springer
ISBN: 9402411461
Category : Mathematics
Languages : en
Pages : 357

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Book Description
This book provides an introduction to age-structured population modeling which emphasizes the connection between mathematical theory and underlying biological assumptions. Through the rigorous development of the linear theory and the nonlinear theory alongside numerics, the authors explore classical equations that describe the dynamics of certain ecological systems. Modeling aspects are discussed to show how relevant problems in the fields of demography, ecology and epidemiology can be formulated and treated within the theory. In particular, the book presents extensions of age-structured modeling to the spread of diseases and epidemics while also addressing the issue of regularity of solutions, the asymptotic behavior of solutions, and numerical approximation. With sections on transmission models, non-autonomous models and global dynamics, this book fills a gap in the literature on theoretical population dynamics. The Basic Approach to Age-Structured Population Dynamics will appeal to graduate students and researchers in mathematical biology, epidemiology and demography who are interested in the systematic presentation of relevant models and mathematical methods.

Computational Methods in Systems Biology

Computational Methods in Systems Biology PDF Author: David Gilbert
Publisher: Springer
ISBN: 3642336361
Category : Computers
Languages : en
Pages : 404

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Book Description
This book constitutes the thoroughly refereed conference proceedings of the 10th International Conference on Computational Methods in Systems Biology, CMSB 2012, held in London, UK, during October 3-5, 2012. The 17 revised full papers and 8 flash posters presented together with the summaries of 3 invited papers were carefully reviewed and selected from 62 submissions. The papers cover the analysis of biological systems, networks, and data ranging from intercellular to multiscale. Topics included high-performance computing, and for the first time papers on synthetic biology.

Statistical Ecology

Statistical Ecology PDF Author: John A. Ludwig
Publisher: John Wiley & Sons
ISBN: 9780471832355
Category : Mathematics
Languages : en
Pages : 362

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Book Description
Ecological community data. Spatial pattern analysis. Species-abundance relations. Species affinity. Community classification. Community ordination. Community interpretation.

Stability in Model Populations (MPB-31)

Stability in Model Populations (MPB-31) PDF Author: Laurence D. Mueller
Publisher: Princeton University Press
ISBN: 0691209944
Category : Science
Languages : en
Pages : 334

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Book Description
Throughout the twentieth century, biologists investigated the mechanisms that stabilize biological populations, populations which--if unchecked by such agencies as competition and predation--should grow geometrically. How is order in nature maintained in the face of the seemingly disorderly struggle for existence? In this book, Laurence Mueller and Amitabh Joshi examine current theories of population stability and show how recent laboratory research on model populations--particularly blowflies, Tribolium, and Drosophila--contributes to our understanding of population dynamics and the evolution of stability. The authors review the general theory of population stability and critically analyze techniques for inferring whether a given population is in balance or not. They then show how rigorous empirical research can reveal both the proximal causes of stability (how populations are regulated and maintained at an equilibrium, including the relative roles of biotic and abiotic factors) and its ultimate, mostly evolutionary causes. In the process, they describe experimental studies on model systems that address the effects of age-structure, inbreeding, resource levels, and population structure on the stability and persistence of populations. The discussion incorporates the authors' own findings on the evolution of population stability in Drosophila. They go on to relate laboratory work to studies of animals in the wild and to develop a general framework for relating the life history and ecology of a species to its population dynamics. This accessible, finely written illustration of how carefully designed experiments can improve theory will have tremendous value for all ecologists and evolutionary biologists.