Methods and Strategies for C–N Bond Formation Reactions PDF Download
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Author: Zahra Taherinia
Publisher: Royal Society of Chemistry
ISBN: 1837671796
Category : Science
Languages : en
Pages : 334
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Book Description
Author: Zahra Taherinia
Publisher: Royal Society of Chemistry
ISBN: 1837671796
Category : Science
Languages : en
Pages : 334
Get Book Here
Book Description
Author: Robert L. Augustine
Publisher: CRC Press
ISBN: 9780824767877
Category : Science
Languages : en
Pages : 480
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Book Description
Author: Zahra Taherinia
Publisher: Royal Society of Chemistry
ISBN: 1837672636
Category : Science
Languages : en
Pages : 388
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Book Description
Organic compounds containing amino groups are one of the most important classes of chemicals in both academia and industry. This class of materials is a very important structural motif in organic synthesis due to its widespread applications in natural products, agrochemicals, pharmaceuticals, and advanced materials. This book is a concise overview of modern approaches to N-alkylation and N-arylation of primary, secondary and tertiary amines using alkylating and arylating reagents with amino sources found in both basic and applied chemical research. The work also discusses key examples of amine synthesis from a sustainable perspective, using deep eutectic solvents and the application of amines in different areas. It is an ideal reference for advanced and postgraduate students as well as academic and industrial chemists working in organic, natural product, catalytic, medicinal, and polymer chemistry.
Author: Matthew L. Crawley
Publisher: John Wiley & Sons
ISBN: 1118309839
Category : Science
Languages : en
Pages : 386
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Book Description
This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs. The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discovery and development – it is a guide, a historical prospective, a practical compendium, and a source of future direction for the field.
Author: Pietro Tundo
Publisher: Springer
ISBN: 3319300733
Category : Science
Languages : en
Pages : 614
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Book Description
Since the industrial revolution, chlorine remains an iconic molecule even though its production by the electrolysis of sodium chloride is extremely energy intensive. The rationale behind this book is to present useful and industrially relevant examples for alternatives to chlorine in synthesis. This multi-authored volume presents numerous contributions from an international spectrum of authors that demonstrate how to facilitate the development of industrially relevant and implementable breakthrough technologies. This volume will interest individuals working in organic synthesis in industry and academia who are working in Green Chemistry and Sustainable Technologies.
Author: Norio Miyaura
Publisher: Springer
ISBN: 354045313X
Category : Science
Languages : en
Pages : 253
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Book Description
In 1972, a very powerful catalytic cycle for carbon-carbon bond formation was 2 first discovered by the coupling reaction of Grignard reagents at the sp -carbon. Over the past 30 years, the protocol has been substantially improved and expanded to other coupling reactions of Li,B,N,O,Al,Si,P,S,Cu,Mn,Zn,In,Sn, and Hg compounds. These reactions provided an indispensable and simple methodology for preparative organic chemists. Due to the simplicity and rel- bility in the carbon-carbon, carbon-heteroatom, and carbon-metalloid bo- formations,as well as high efficiency of the catalytic process,the reactions have been widely employed by organic chemists in various fields. Application of the protocol ranges from various syntheses of complex natural products to the preparation of biologically relevant molecules including drugs, and of sup- molecules, and to functional materials. The reactions on solid surfaces allow robot synthesis and combinatorial synthesis. Now, many organic chemists do not hesitate to use transition metal complexes for the transformation of org- ic molecules. Indeed, innumerable organic syntheses have been realized by the catalyzed reactions of transition metal complexes that are not achievable by t- ditional synthetic methods. Among these, the metal-catalyzed cross-coupling reactions have undoubtedly contributed greatly to the development of such a new area of “metal-catalyzed organic syntheses”. An excellent monograph for the cross-coupling reactions and other met- catalyzed C-C bond-forming reactions recently appeared in Metal-catalyzed Cross-coupling Reactions (Wiley-VCH,1998).
Author: Joffrey Vrijdag
Publisher:
ISBN: 9781536176957
Category : Science
Languages : en
Pages : 268
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Book Description
"Cross-Coupling Reactions: An Overview opens with an overview of the fundamentals and applications of the young and fast developing area of transition metal catalyzed/mediated oxidative (dehydrogenative) C-H/C-H coupling reactions between two (hetero)arenes. Continuing, the authors highlight the recent advances regarding the ligand supported transition metal-catalyzed domino (cascade) or one-pot syntheses of various heterocycles involving cross-coupling reactions. The recent advances in Cu catalyzed tandem reactions for heterocycle synthesis are also addressed. Cu metal chemistry has garnered attention as a potential alternative to precious transition metals, being cheaper, more sustainable and more easily available. A comprehensive account of research on green chemical routes is provided, involving various palladium metal-based catalysts utilized in facilitating cross-coupling reaction in aqueous media. Reported decarboxylative cross-coupling reactions are discussed along with suitable examples, focusing on their mechanism of action"--
Author: Gwilherm Evano
Publisher: John Wiley & Sons
ISBN: 1118060458
Category : Science
Languages : en
Pages : 851
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Book Description
Providing comprehensive insight into the use of copper in cross-coupling reactions, Copper-Mediated Cross-Coupling Reactions provides a complete up-to-date collection of the available reactions and catalytic systems for the formation of carbon-heteroatom and carbon-carbon bonds. This essential reference covers a broad scope of copper-mediated reactions, their variations, key advances, improvements, and an array of academic and industrial applications that have revolutionized the field of organic synthesis. The text also discusses the mechanism of these transformations, the use of copper as cost-efficient alternative to palladium, as well as recently developed methods for conducting copper-mediated reactions with supported catalysts.
Author: Andrei Hent
Publisher: Academic Press
ISBN: 0128128704
Category : Science
Languages : en
Pages : 886
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Book Description
Strategies and Solutions to Advanced Organic Reaction Mechanisms: A New Perspective on McKillop's Problems builds upon Alexander (Sandy) McKillop's popular text, Solutions to McKillop's Advanced Problems in Organic Reaction Mechanisms, providing a unified methodological approach to dealing with problems of organic reaction mechanism. This unique book outlines the logic, experimental insight and problem-solving strategy approaches available when dealing with problems of organic reaction mechanism. These valuable methods emphasize a structured and widely applicable approach relevant for both students and experts in the field. By using the methods described, advanced students and researchers alike will be able to tackle problems in organic reaction mechanism, from the simple and straight forward to the advanced. - Provides strategic methods for solving advanced mechanistic problems and applies those techniques to the 300 original problems in the first publication - Replaces reliance on memorization with the understanding brought by pattern recognition to new problems - Supplements worked examples with synthesis strategy, green metrics analysis and novel research, where available, to help advanced students and researchers in choosing their next research project
Author: Stéphane Caron
Publisher: John Wiley & Sons
ISBN: 1119448859
Category : Science
Languages : de
Pages : 850
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Book Description
This book is a hands-on guide for the organic chemist. Focusing on the most reliable and useful reactions, the chapter authors provide the information necessary for a chemist to strategically plan a synthesis, as well as repeat the procedures in the laboratory. Consolidates all the key advances/concepts in one book, covering the most important reactions in organic chemistry, including substitutions, additions, eliminations, rearrangements, oxidations, reductions Highlights the most important reactions, addressing basic principles, advantages/disadvantages of the methodology, mechanism, and techniques for achieving laboratory success Features new content on recent advances in CH activation, photoredox and electrochemistry, continuous chemistry, and application of biocatalysis in synthesis Revamps chapters to include new and additional examples of chemistry that have been demonstrated at a practical scale
