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Author: Giuseppe Prota
Publisher: Academic Press
ISBN: 0323139396
Category : Science
Languages : en
Pages : 305
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Book Description
This volume covers all aspects of melanin pigmentation, providing a concise, comprehensive picture of new knowledge gained at the frontiers of research. It draws heavily on the author's 30-year activity in the field and his continuing work with specialists of widely diverse disciplines. The core of the volume deals with the structure, physicochemical properties, and biosynthesis of the major classes of melanin pigments, including neuromelanins. Further discussions include the biology of the various types of pigment-producing cells, the structure and mode of action of tyrosinase, and the chemistry of urinary melanogens and their biomedical applications as metabolic markers of melanocyte activity, especially for the follow-up of malignant melanoma. Finally, the volume considers progress in the photobiology and photochemistry of melanins, with special emphasis on the controversial role of these pigments in skin photoprotection. Melanins and Melanogenesis is ideally suited as a basic guide for newcomers, and a handy source of specific information for practitioners in academic, medical, and industrial settings.
Author: Giuseppe Prota
Publisher: Academic Press
ISBN: 0323139396
Category : Science
Languages : en
Pages : 305
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Book Description
This volume covers all aspects of melanin pigmentation, providing a concise, comprehensive picture of new knowledge gained at the frontiers of research. It draws heavily on the author's 30-year activity in the field and his continuing work with specialists of widely diverse disciplines. The core of the volume deals with the structure, physicochemical properties, and biosynthesis of the major classes of melanin pigments, including neuromelanins. Further discussions include the biology of the various types of pigment-producing cells, the structure and mode of action of tyrosinase, and the chemistry of urinary melanogens and their biomedical applications as metabolic markers of melanocyte activity, especially for the follow-up of malignant melanoma. Finally, the volume considers progress in the photobiology and photochemistry of melanins, with special emphasis on the controversial role of these pigments in skin photoprotection. Melanins and Melanogenesis is ideally suited as a basic guide for newcomers, and a handy source of specific information for practitioners in academic, medical, and industrial settings.
Author: Jan Borovansky
Publisher: John Wiley & Sons
ISBN: 3527644555
Category : Science
Languages : en
Pages : 395
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Book Description
The surface pigmentation of vertebrates is controlled by specialized cells able to synthesize a variety of pigments collectively known as melanins. Recent research has shown that melanins are produced not only in the skin but also in many other sites such as the eye, inner ear, muscles, etc., - where they are engaged in some unanticipated roles. The details of the synthetic pathway, the complexities of its regulation and biological significance that have been unravelled in recent research comprise a fascinating story and are of key importance in understanding the nature of diseases, including malignant melanoma one of the most rapidly spreading cancers.
Author: Jan Borovansky
Publisher: John Wiley & Sons
ISBN: 3527328920
Category : Science
Languages : en
Pages : 395
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Book Description
The surface pigmentation of vertebrates is controlled by specialized cells able to synthesize a variety of pigments collectively known as melanins. Recent research has shown that melanins are produced not only in the skin but also in many other sites such as the eye, inner ear, muscles, etc., - where they are engaged in some unanticipated roles. The details of the synthetic pathway, the complexities of its regulation and biological significance that have been unravelled in recent research comprise a fascinating story and are of key importance in understanding the nature of diseases, including malignant melanoma one of the most rapidly spreading cancers.
Author: Ryo Kishida
Publisher: Springer Nature
ISBN: 981161315X
Category : Science
Languages : en
Pages : 91
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Book Description
This book discusses recent advances in theoretical–computational studies on the biosynthesis of melanin pigment (melanogenesis). These advances are being driven by the development of high-performance computers, new experimental findings, and extensive work on medical applications involving the control of pigmentation and the treatment of challenging dermatological diseases. Understanding the elementary processes involved in chemical reactions at the atomic scale is important in biochemical reaction design for effective control of the pigmentary system. Accordingly, the book focuses on the elementary steps involved in melanogenesis, which crucially affect the composition of the resulting melanin pigment by means of competitive reactions. The book also addresses reactions analogous to melanogenesis, with a focus on o-quinone reactions, which are especially important for understanding melanogenesis-associated cytotoxicity.
Author: Somesh Gupta
Publisher: John Wiley & Sons
ISBN: 1118937414
Category : Medical
Languages : en
Pages : 533
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Book Description
Practical guidance based on expert experience and evidence for developing management strategies for vitiligo This complete guide to vitiligo provides a full appraisal of strategy for the treatment of this autoimmune disease that affects 1-2% of the world’s population. It addresses all aspects of vitiligo, covering the science, medical and surgical therapies, and the psychological evaluations and approaches based on the proper understanding of the causes and classification of a particular case. Management of vitiligo is challenging and requires a multipronged approach. Vitiligo: Medical and Surgical Management is a comprehensive, timely, state-of-the-art resource that will help those involved with affected patients better understand and treat this disease, which takes its toll on the mental wellness of those afflicted by it. It takes an evidenced-based approach to the disease’s treatment; provides an overview of the surgical management; covers tissue and cellular grafting; and more. Thoroughly guides those involved in the clinical aspects of vitiligo Aids diagnosis and classification of severity Balances evidence and experience Compiled by world-leading expert editors Comprehensive in nature, Vitiligo: Medical and Surgical Management contains a strong practical element, and is a welcome go-to source for practicing dermatologists and those training to become a dermatologist.
Author: James J. Nordlund
Publisher: John Wiley & Sons
ISBN: 140515733X
Category : Medical
Languages : en
Pages : 1248
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Book Description
The most comprehensive and integrated book on pigmentation The Pigmentary System, Second Edition, gathers into one convenient, all-inclusive volume a wealth of information about the science of pigmentation and all the common and rare clinical disorders that affect skin color. The two parts, physiology (science) and pathophysiology (clinical disorders), are complementary and annotated so that those reading one part can easily refer to relevant sections in the other. For the clinician interested in common or rare pigment disorders or the principles of teaching about such disorders, this book provides an immediate and complete resource on the biologic bases for these disorders. For the scientist studying the biology of melanocyte function, the book provides a list of disorders that are related to basic biological functions of melanocytes. New features of this Second Edition include: Completely new section on the basic science of pigmentation – explaining the integration of melanocyte functions with other epidermal cells and with various organ systems like the immune system New chapters on pigmentary disorders related to intestinal diseases, the malignant melanocyte, benign proliferations of melanocytes (nevi) and phototherapy with narrow band UV All clinical chapters include the latest genetic findings and advances in therapy More than 400 color images of virtually all clinical disorders The book is ideal for all dermatologists and especially those interested in disorders of pigmentation. It is of particular use for pediatric dermatologists and medical geneticists caring for patients with congenital and genetic pigmentary disorders. This authoritative volume will fill the gap for dermatology training programs that do not have local experts on pigmentation. Basic and cosmetic scientists studying pigmentation and melanocytes will find the science and clinical correlations very useful in showing human significance and relevance to the results of their studies.
Author: Guillermo Gosset
Publisher: Springer Nature
ISBN: 3031277996
Category : Science
Languages : en
Pages : 150
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Book Description
This book provides an up-to-date overview of the biological functions of melanins, their biotechnological production, and their industrial applications. The melanins form a group of polymeric pigments found in most organisms. These natural products are generated by the oxidation of phenolic and indolic molecules yielding melanins, which include eumelanin, pheomelanin, pyomelanin, and the allomelanins. These pigments have diverse biological functions, including photoprotection, thermoregulation, antioxidation, virulence, and metal ion sequestration. Melanins have physicochemical properties that have proven useful in the optical, electronic, material, agriculture, cosmetic, pharmaceutical, and medical industries. The chapters in this book provide an in-depth analysis of the current issues and challenges in this field. Topics covered include the properties, biogenesis, and evolution of melanosomes. The book also addresses the synthesis and industrial production of melanins by microorganisms. The metabolic pathways for the synthesis of several types of polymeric pigments in microorganisms and their role in pathogenesis are reviewed. The large-scale production and purification of melanins to provide this product for industrial applications is a formidable challenge. Two chapters present and discuss the state-of-the-art used for the generation of microbial melanin-production strains and the processes for the biotechnological synthesis and purification of these pigments. Melanins are polymers that can interact with metals, a chapter reviews this capacity in the context of technological applications, including electrochemical energy storage and metal recovery. These polymers are materials having favorable characteristics for photonic applications, including UV blocking and broadband absorption. The current advances in the application of these pigments in optically active materials are presented and discussed.
Author: A. S. Breathnach
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 20
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Book Description
Author: R. A. Nicolaus
Publisher:
ISBN:
Category : Melanin
Languages : en
Pages : 328
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Book Description
Author: Om V. Singh
Publisher: John Wiley & Sons
ISBN: 1119166179
Category : Science
Languages : en
Pages : 321
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Book Description
Recent technological advances have provided unique opportunities for the exploration of alternatives to the industrial use of chemically produced synthetic colors. The most promising developments in this area have been in bio-pigmentation derived from microorganisms. This groundbreaking book reviews the current state of the science of bio-pigmentation, providing important insights into the molecular mechanisms of microbial biosynthesis of industrial pigments. Featuring contributions by leading researchers from both industry and academe, it explores the latest advances in the use of bio-pigments as safe, sustainable alternatives to chemically synthesized pigments, and provides extensive coverage the most promising sources of bio-pigments within the food, feed, and pharmaceutical industries. • Proposes microbial uniqueness of coloration in variety of food, feed and pharmaceuticals • Covers the basic science behind bio-pigmentation as well as the latest advances in the field • Describes detection strategies for screening and identifying color producing microorganisms under varying environmental conditions • Provides an exhaustive review of the literature on color producing extremophiles and offers fascinating insights into color production as a stress response in extremophiles • Explores microbial molecular mechanisms of color production, with special coverage of color production as secondary metabolites under environmental stress Bio-pigmentation and Biotechnological Implementations is required reading for professionals and post-doctoral students of microbiology, applied microbiology, food microbiology, food science, and food biochemistry. It is a valuable working resource for scientists working in color-dependent food, feed, and pharmaceuticals.