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Author: Mark Dennis
Publisher: Elsevier Health Sciences
ISBN: 0729585611
Category : Medical
Languages : en
Pages : 792
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Book Description
2016 BMA Medical Book Awards Highly Commended in the Medicine Category! What causes that condition? What does it mean? Organised by body system, Mechanisms of Clinical Signs, 2nd Edition explains the underlying mechanism and value of the clinical signs you are expected to know, and the conditions they indicate. Each chapter contains descriptions of clinical signs, a list of the conditions they are associated with (what conditions the signs indicate), an explanation of the mechanism and the ‘value’ of those signs (how reliable they are as an indication of a condition). There is a uniform set of subheadings for each sign: Description Condition/s associated with Mechanism/s Sign value The explanations for the mechanisms underlying each sign are brief but accurate and informative, and provide sufficient information for the reader to understand the mechanism: Signs are ordered alphabetically within each chapter outlining a specific body system. Extensive reference lists of up-to-date literature strengthen the authority of the content. Video and audio content presents real life evaluation scenarios of clinical signs. Clinical Pearls highlight the main signs which students and trainees should look out for to help them identify conditions with which the patients present. A Student Consult eBook is available with the purchase of a print book, and provides access to a total of 200 multiple choice questions covering the 7 body systems, to test students and trainees’ knowledge of the content. The eBook contains links to audio and video examples of particular signs which have to be heard or observed over a period of time in order to be identified correctly, e.g. Agonal respiration in Chapter 2 Respiratory Signs. New images are added to depict clinical signs where no images were present in the previous edition.
Author: Mark Dennis
Publisher: Elsevier Health Sciences
ISBN: 0729585611
Category : Medical
Languages : en
Pages : 792
Get Book
Book Description
2016 BMA Medical Book Awards Highly Commended in the Medicine Category! What causes that condition? What does it mean? Organised by body system, Mechanisms of Clinical Signs, 2nd Edition explains the underlying mechanism and value of the clinical signs you are expected to know, and the conditions they indicate. Each chapter contains descriptions of clinical signs, a list of the conditions they are associated with (what conditions the signs indicate), an explanation of the mechanism and the ‘value’ of those signs (how reliable they are as an indication of a condition). There is a uniform set of subheadings for each sign: Description Condition/s associated with Mechanism/s Sign value The explanations for the mechanisms underlying each sign are brief but accurate and informative, and provide sufficient information for the reader to understand the mechanism: Signs are ordered alphabetically within each chapter outlining a specific body system. Extensive reference lists of up-to-date literature strengthen the authority of the content. Video and audio content presents real life evaluation scenarios of clinical signs. Clinical Pearls highlight the main signs which students and trainees should look out for to help them identify conditions with which the patients present. A Student Consult eBook is available with the purchase of a print book, and provides access to a total of 200 multiple choice questions covering the 7 body systems, to test students and trainees’ knowledge of the content. The eBook contains links to audio and video examples of particular signs which have to be heard or observed over a period of time in order to be identified correctly, e.g. Agonal respiration in Chapter 2 Respiratory Signs. New images are added to depict clinical signs where no images were present in the previous edition.
Author: Julian A. Smith
Publisher: Elsevier Health Sciences
ISBN: 0729585026
Category : Medical
Languages : en
Pages : 556
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Book Description
Is surgery required? Is the patient effectively communicating symptoms to make the correct clinical diagnosis? Clinical Problems in Surgery, 3rd Edition supports medical students in applying clinical reasoning to problems they encounter in a clinical setup. Individual chapters are dedicated to specific regions of the body where surgeons encounter most of the problems. The content structure follows the logical step-by-step process of introducing a clinical problem; seeking history and conducting physical examination; diagnosing the patient and devising a treatment plan based on this informed diagnosis. Each chapter discusses the clinical presentations with which surgeons are most commonly faced Each chapter is dedicated to a range of such problems within a particular region of the body Incorporation of the latest RACS guidelines on surgery A new Chapter 14, titled Ophthalmological Problems, expands the latest advancements in surgical treatments of such problems Many line drawings from the previous edition have been replaced with clinical photos to emphasise real-life clinical scenarios which surgeons encounter on a daily basis
Author: Jerome Badaut
Publisher: Academic Press
ISBN: 0128031972
Category : Medical
Languages : en
Pages : 554
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Book Description
Brain Edema: From Molecular Mechanisms to Clinical Practice brings together the most widely recognized experts in experimental and clinical brain edema research to review the current knowledge gathered on the molecular and cellular pathophysiology and clinical management of brain edema. This timely book also discusses future directions of research and treatment. Brain edema is an integral and acutely life-threatening part of the pathophysiology of multiple cerebral and non-cerebral disorders, including traumatic brain injury, cerebral ischemia, brain tumors, cardiac arrest, altitude sickness and liver failure. Affecting millions worldwide, research over the past few years has shown that a plethora of complex molecular and cellular mechanisms contribute to this pathological accumulation of water in the brain parenchyma. In parallel, the development of new neuroimaging tools has provided a new way to examine how edema develops longitudinally and in real time, both in pre-clinical models and in patients. Despite intense research over the past few decades, therapeutic options are still limited and sometimes not effective. Presents a comprehensive understanding of the molecular mechanisms involved in edema formation and resolution Discusses the specific role of edema development in several pathologies, including traumatic brain injury, stroke, brain tumors, cardiac arrest, and liver failure Proposes a new classification of edema based on molecular processes Discusses clinical management of new clinical trials coming from pre-clinical studies Addresses the possible link between edema formation, other molecular and cellular processes, including inflammation and neuroinflammation
Author: Paul Watson
Publisher: Elsevier Health Sciences
ISBN: 0729584992
Category : Medical
Languages : en
Pages : 700
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Book Description
Be punctual, hard-working and honest, but most importantly – be excellent. Written by residents, for interns and residents, the Junior Doctor Survival Guide is a thorough, focused summary of everything you need to know to get through your internship and residency (relatively) intact. It provides advice on seeking help from your senior clinicians, ensuring ethical practice and decision making, conducting an efficient ward round and carrying out emergency assessments and includes a concise overview of the salient features of specialist medical and surgical care in both in- and outpatient settings. Covering both clinical and professional contexts, this guide will support you to build your confidence in applying the principles you learned in medical school to the real world. Scenario boxes – how difficult conversations should be approached Common medications – quick reference tables of common medications and dosages Clinical abbreviations and acronyms – a comprehensive list of common abbreviations and acronyms used throughout clinical settings. Full eBook on ExpertConsult
Author: Arpad Szallasi
Publisher: Academic Press
ISBN: 0124200796
Category : Medical
Languages : en
Pages : 530
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Book Description
TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use is authored by experts across academia and industry, providing readers with a complete picture of the therapeutic potential and challenges associated with using TRP channels as drug targets. This book offers a unique clinical approach by covering compounds that target TRP channels in pre-clinical and clinical phases, also offering a discussion of TRP channels as biomarkers. An entire section is devoted to the novel and innovative uses of these channels across a variety of diseases, offering strategies that can be used to overcome the adverse effects of first generation TRPV1 antagonists. Intended for all researchers and clinicians working toward the development of successful drugs targeting TRP channels, this book is an essential resource chocked full of the latest clinical data and findings. Contains comprehensive coverage of TRP channels as therapeutic targets, from emerging clinical indications to completed clinical trials Discusses TRP channels as validated targets, ranging from obesity and diabetes through cancer and respiratory disorders, kidney diseases, hypertension, neurodegenerative disorders, and more Provides critical analysis of the complications and side effects that have surfaced during clinical trials, offering evidence-based suggestions for overcoming them
Author: Edgar Garcia-Rill
Publisher: Academic Press
ISBN: 0128016329
Category : Medical
Languages : en
Pages : 330
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Book Description
Waking and the Reticular Activating System in Health and Disease provides a comprehensive overview on the “activating properties of the RAS. In health, the RAS provides the basis against which we assess the external world, and in disease it distorts that world and shatters our self-image. This book describes the physiology of each process, how it is disturbed in each disorder, and what the most appropriate treatment should be. Dr. Garcia-Rill, along with contributions from leading specialists, discusses the understanding of the RAS as a system not only modulating waking, but also in charge of survival mechanisms such as fight vs flight responses and reflexes. The full spectrum of these functions helps explain the complexity of symptoms evident in such disorders as disparate as schizophrenia and Parkinson’s disease. The book reviews the mechanisms that control waking and arousal, and especially how those mechanisms malfunction in certain neurological and psychiatric disorders. First comprehensive overview on the RAS and its role in schizophrenia, major depression, autism, Parkinson’s, Alzheimer’s, and other neurologic and mental diseases Offers a new way of thinking about brain function and the role of the RAS in our waking lives Written by a leading translational neuroscience researcher with contributions by specialists in the field
Author: John Mitrofanis
Publisher: Morgan & Claypool Publishers
ISBN: 1643277200
Category : Science
Languages : en
Pages : 172
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Book Description
Parkinson's disease is a neurological disorder with cardinal motor signs of resting tremor, bradykinesia and lead-pipe rigidity. In addition, many patients display non-motor symptoms, including a diminished sensation of smell, gastrointestinal problems, various disorders of sleep and some cognitive impairment. These clinical features - particularly the motor signs - manifest after a progressive death of many dopaminergic neurones in the brain. Although currently available, conventional therapies can reduce the signs of the disease, the progression of this neuronal death has proved difficult to slow or stop, and the condition is relentlessly progressive. Hence, there is a real need to develop a treatment that is neuroprotective, one that slows the pathology of the disease effectively. At present, there are several neuroprotective therapies in the experimental pipeline, but these are for the patients of tomorrow. This book focuses on two therapies that are readily available for the patients of today. They involve the use of exercise and light (i.e. photobiomodulation, the use of red to infrared light therapy (λ=600-1070nm) on body tissues). The two therapies are tied together in several ways. First, in animal models of Parkinson's disease, they each have been shown to offer the key feature of neuroprotection, stimulating a series of built-in protective mechanisms within the neurones, that helps their survival, to self-protect and/or self-repair. There are also some promising indications of neuroprotection and many beneficial outcomes in parkinsonian patients. Further, both exercise and light therapies are similar in that they are non-invasive and safe to use, with no known adverse side-effects, making their combination with the conventional therapies, such as dopamine replacement drug therapy and deep brain stimulation, all the more feasible. Given the heterogeneity of Parkinson's disease in humans, tackling the condition from a range of different angles - with a number of different therapies - would only serve to enhance the positive outcomes. This book considers the use of exercise and light therapies, proposing that they have the potential to make a powerful "dynamic duo", offering a most effective neuroprotective treatment option to patients.
Author: Adrian Dalca
Publisher: Academic Press
ISBN: 9780128139684
Category : Technology & Engineering
Languages : en
Pages : 0
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Book Description
Imaging Genetics presents the latest research in imaging genetics methodology for discovering new associations between imaging and genetic variables, providing an overview of the state-of the-art in the field. Edited and written by leading researchers, this book is a beneficial reference for students and researchers, both new and experienced, in this growing area. The field of imaging genetics studies the relationships between DNA variation and measurements derived from anatomical or functional imaging data, often in the context of a disorder. While traditional genetic analyses rely on classical phenotypes like clinical symptoms, imaging genetics can offer richer insights into underlying, complex biological mechanisms.
Author: Gregory Hickok
Publisher: Academic Press
ISBN: 0124078621
Category : Psychology
Languages : en
Pages : 1188
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Book Description
Neurobiology of Language explores the study of language, a field that has seen tremendous progress in the last two decades. Key to this progress is the accelerating trend toward integration of neurobiological approaches with the more established understanding of language within cognitive psychology, computer science, and linguistics. This volume serves as the definitive reference on the neurobiology of language, bringing these various advances together into a single volume of 100 concise entries. The organization includes sections on the field's major subfields, with each section covering both empirical data and theoretical perspectives. "Foundational" neurobiological coverage is also provided, including neuroanatomy, neurophysiology, genetics, linguistic, and psycholinguistic data, and models. Foundational reference for the current state of the field of the neurobiology of language Enables brain and language researchers and students to remain up-to-date in this fast-moving field that crosses many disciplinary and subdisciplinary boundaries Provides an accessible entry point for other scientists interested in the area, but not actively working in it – e.g., speech therapists, neurologists, and cognitive psychologists Chapters authored by world leaders in the field – the broadest, most expert coverage available
Author: Mitesh Kumar Dwivedi
Publisher: Academic Press
ISBN: 0128237341
Category : Health & Fitness
Languages : en
Pages : 531
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Book Description
Probiotics in The Prevention and Management of Human Diseases: A Scientific Perspective addresses the use of probiotics and their mechanistic aspects in diverse human diseases. In particular, the mechanistic aspects of how these probiotics are involved in mitigating disease symptoms (novel approaches and immune-mechanisms induced by Probiotics), clinical trials of certain probiotics, and animal model studies will be presented through this book. In addition, the book covers the role of probiotics in prevention and management aspects of crucial human diseases, including multidrug resistant infections, hospital acquired infections, allergic conditions, autoimmune diseases, metabolic disorders, gastrointestinal diseases, neurological disorders, and cancers. Finally, the book addresses the use of probiotics as vaccine adjuvants and as a solution for nutritional health problems and describes the challenges of using probiotics in management of human disease conditions as well as their biosafety concerns. Intended for nutrition researchers, microbiologists, physiologists, and researchers in related disciplines as well as students studying these topics require a resource that addresses the specific role of probiotics in the prevention and management of human disease. Contains information on the use of probiotics in significant human diseases, including antibiotic resistant microbial infections Presents novel applications of probiotics, including their use in vaccine adjuvants and concept of pharmabiotics Includes case studies and human clinical trials for probiotics in diverse disease conditions and explores the role of probiotics in mitigation of the symptoms of disease
