Magnetic Resonance Spectroscopy of GABA and Glutamate in Mental Health

Magnetic Resonance Spectroscopy of GABA and Glutamate in Mental Health PDF Author: Maria Concepcion Garcia Otaduy
Publisher: Frontiers Media SA
ISBN: 2889745465
Category : Science
Languages : en
Pages : 186

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Book Description

Magnetic Resonance Spectroscopy of GABA and Glutamate in Mental Health

Magnetic Resonance Spectroscopy of GABA and Glutamate in Mental Health PDF Author: Maria Concepcion Garcia Otaduy
Publisher: Frontiers Media SA
ISBN: 2889745465
Category : Science
Languages : en
Pages : 186

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Book Description


The Neurobiological Basis of Suicide

The Neurobiological Basis of Suicide PDF Author: Yogesh Dwivedi
Publisher: CRC Press
ISBN: 143983881X
Category : Medical
Languages : en
Pages : 485

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Book Description
With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

Rapid Acting Antidepressants

Rapid Acting Antidepressants PDF Author:
Publisher: Academic Press
ISBN: 0128201908
Category : Medical
Languages : en
Pages : 404

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Book Description
The Advances in Pharmacology series presents a variety of chapters from the best authors in the field. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series

Drug Discovery for Psychiatric Disorders

Drug Discovery for Psychiatric Disorders PDF Author: Zoran Rankovic
Publisher: Royal Society of Chemistry
ISBN: 1849734941
Category : Science
Languages : en
Pages : 615

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Book Description
The discovery and development of effective medicines for the treatment of psychiatric disorders such as schizophrenia and depression has been heralded as one of the great medical achievements of the past century. Indeed, the profound impact of these medicines on our understanding of the pathophysiology underlying these diseases, the treatment of psychiatric patients and even our social perception of mental illnesses cannot be underestimated. However, there is still an urgent medical need for even more effective, safe and well-tolerated treatments. For example, currently available treatments for schizophrenia address mainly the positive symptoms and largely neglect the negative symptoms and cognitive disfunction which greatly impact overall morbidity. Similarly, whilst the current first line antidepressants show significantly improved side effect profiles compared to the first generation therapies, there still up to 40% of patients who are treatment resistant, and even in the patient population which responds well, the onset of action is slow at typically 2-3 weeks. The aim of this book is to provide the first point of call for those involved or just interested in this rapidly expanding and increasingly fragmented field of research and drug discovery. The editors will combine their wide ranging experience and extensive network of contacts with leading scientists and opinion leaders in this field to provide an authoritative reference text covering the evolution, major advances, challenges and future directions in drug discovery and medicinal chemistry for major psychiatric disorders, such as schizophrenia, depression, anxiety, ADHD, bipolar disorder, addiction and autism.

Magnetic Resonance Spectroscopy

Magnetic Resonance Spectroscopy PDF Author: Charlotte Stagg
Publisher: Academic Press
ISBN: 0124016979
Category : Medical
Languages : en
Pages : 376

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Book Description
Magnetic Resonance Spectroscopy: Tools for Neuroscience Research and Emerging Clinical Applications is the first comprehensive book for non-physicists that addresses the emerging and exciting technique of magnetic resonance spectroscopy. Divided into three sections, this book provides coverage of the key areas of concern for researchers. The first, on how MRS is acquired, provides a comprehensive overview of the techniques, analysis, and pitfalls encountered in MRS; the second, on what can be seen by MRS, provides essential background physiology and biochemistry on the major metabolites studied; the final sections, on why MRS is used, constitutes a detailed guide to the major clinical and scientific uses of MRS, the current state of teh art, and recent innovations. Magnetic Resonance Spectroscopy will become the essential guide for people new to the technique and give those more familiar with MRS a new perspective. - Chapters written by world-leading experts in the field - Fully illustrated - Covers both proton and non-proton MRS - Includes the background to novel MRS imaging approaches

Fiber Pathways of the Brain

Fiber Pathways of the Brain PDF Author: Jeremy D. Schmahmann
Publisher: OUP USA
ISBN: 0195388267
Category : Medical
Languages : en
Pages : 674

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Book Description
The text is enriched throughout by close attention to functional aspects of the anatomical observations."--Jacket.

Magnetic Resonance Spectroscopy Diagnosis of Neurological Diseases

Magnetic Resonance Spectroscopy Diagnosis of Neurological Diseases PDF Author: Else Rubaek Danielsen
Publisher: CRC Press
ISBN: 1482270102
Category : Medical
Languages : en
Pages : 342

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Book Description
Demonstrates how MRS offers a useful tool for the noninvasive biochemical analysis of the brain. The book covers over 70 clinical cases and more than 100 spectra that enhance skills at interpreting MRS, including minimizing errors, highlighting artifacts, and expanding the clinical usefulness of this diagnostic modality.

Neurodevelopment and Schizophrenia

Neurodevelopment and Schizophrenia PDF Author: Matcheri S. Keshavan
Publisher: Cambridge University Press
ISBN: 9780521823319
Category : Medical
Languages : en
Pages : 576

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Book Description
This book was originally published in 2004 and concerns developmental neurobiology. In the decade preceding publication, developmental neurobiology made important strides towards elucidating the pathophysiology of psychiatric disorders. Nowhere has this link between basic science and clinical insights become clearer than in the field of schizophrenia research. Each contributor to this volume provides a fresh overview of the relevant research, including directions for further investigation. The book begins with a section on advances in developmental neurobiology. This is followed by sections on etiological and pathophysiological developments, and models that integrate this knowledge. The final section addresses the clinical insights that emerge from the developmental models. This book will be valuable to researchers in psychiatry and neurobiology, students in psychology, and all mental health practitioners.

Electroconvulsive and Neuromodulation Therapies

Electroconvulsive and Neuromodulation Therapies PDF Author: Conrad M. Swartz
Publisher: Cambridge University Press
ISBN: 1139478869
Category : Medical
Languages : en
Pages : 619

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Book Description
Electroconvulsive therapy (ECT) is a psychiatric treatment involving the induction of a seizure through the transmission of electricity in the brain. Because of exploitation movies and greatly heightened drug company promotional activities ECT was used less frequently in the 1980s and 1990s. Eventually these movies were understood as unrealistic. Now these drugs are increasingly recognized as dangers to body health. Because of recent refinements and a far better scientific understanding of the clinical procedures and mechanisms underpinning ECT, this treatment modality has seen a resurgence in use and widespread appreciation of its safety. This book is the new definitive reference on electroconvulsive and neuromodulation therapies. It comprehensively covers the scientific basis and clinical practice of ECT as well as comparisons between ECT and medication therapies including the new generation of antipsychotic drugs. It also provides readers with administrative perspectives and specific details for the management of this modality in clinical practice. The new forms of nonconvulsive electrical and magnetic brain stimulation therapy are also covered in detail, in a separate section. The chapter authors are leading scholars and clinicians.

Obsessive-compulsive Disorder

Obsessive-compulsive Disorder PDF Author: Christopher Pittenger
Publisher: Oxford University Press
ISBN: 0190228164
Category : Medical
Languages : en
Pages : 777

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Book Description
Obsessive-compulsive disorder (OCD) affects one person in 40 and can cause great suffering. This volume provides the first comprehensive summary of our understanding of this enigmatic condition, summarizing current work ranging from genetics and neurobiology through cognitive psychology, treatment, personal experiences, and societal implications.