IARC Monographs on the Evaluation of Carcinogenic Risks to Humans PDF Download
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Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher:
ISBN:
Category : Carcinogens
Languages : en
Pages : 452
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Book Description
Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher:
ISBN:
Category : Carcinogens
Languages : en
Pages : 452
Get Book Here
Book Description
Author: International Program on Chemical Safety
Publisher:
ISBN: 9789283211839
Category : Medical
Languages : en
Pages : 584
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Book Description
This volume contains the papers presented at a meeting held in December 1985 to review the conduct and use of long- and short- term assays for the detection of chemical carcinogens. The meeting was attended by about 60 experts in the fields of carcinogenesis, mutagenesis, and cell biology. The series of reports on long-term carcinogenicity assays pay particular attention to three topics: the role of pharmacokinetic data, early preneoplastic lesions in carcinogenesis, and the possibility for discerning the relative contribution of carcinogens to various stages of carcinogenesis. The reports on short-term assays summarize, among other points, the principle and scientific basis of each assay and its relevance to carcinogen detection and to the multistage process of carcinogenesis.
Author: Charles Ralph Buncher
Publisher: CRC Press
ISBN: 9780824790738
Category : Mathematics
Languages : en
Pages : 606
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Book Description
This rewritten and updated second edition provides comprehensive information on the wide-ranging applications of statistics in the pharmacological field. Focusing on practical aspects, it sets out to bridge the gap between industry and academia.;Reflecting the changes that have taken place since publication of the first edition, this volume covers new topics such as: cancer clinical trials, clinical trials of AIDS patients and animal tumorigenicity studies; the development of antiepileptic drugs; the role of epidemiology in postmarketing trials and adverse drug experience; computer-assisted new drug application (CANDA) submissions; contract research organizations; interim analysis in clinical trials; and room-temperature tests for the stability of drugs.;This work is intended as: a reference for statisticians, biostatisticians, pharmacologists, administrators, managers, and scientists in the pharmaceutical industry; and a text for graduate students taking courses in applied statistics or pharmaceutical statistics.
Author: A. Wallace Hayes
Publisher: CRC Press
ISBN: 9780849337789
Category : Medical
Languages : en
Pages : 2304
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Book Description
Founded on the paradox that all things are poisons and the difference between poison and remedy is quantity, the determination of safe dosage forms the base and focus of modern toxicology. In order to make a sound determination there must be a working knowledge of the biologic mechanisms involved and of the methods employed to define these mechanisms. While the vastness of the field and the rapid accumulation of data may preclude the possibility of absorbing and retaining more than a fraction of the available information, a solid understanding of the underlying principles is essential. Extensively revised and updated with four new chapters and an expanded glossary, this fifth edition of the classic text, Principles and Methods of Toxicology provides comprehensive coverage in a manageable and accessible format. New topics include 'toxicopanomics', plant and animal poisons, information resources, and non-animal testing alternatives. Emphasizing the cornerstones of toxicology-people differ, dose matters, and things change, the book begins with a review of the history of toxicology and followed by an explanation of basic toxicological principles, agents that cause toxicity, target organ toxicity, and toxicological testing methods including many of the test protocols required to meet regulatory needs worldwide. The book examines each method or procedure from the standpoint of technique and interpretation of data and discusses problems and pitfalls that may be associated with each. The addition of several new authors allow for a broader and more diverse treatment of the ever-changing and expanding field of toxicology. Maintaining the high-quality information and organizational framework that made the previous editions so successful, Principles and Methods of Toxicology, Fifth Edition continues to be a valuable resource for the advanced practitioner as well as the new disciple of toxicology.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309053919
Category : Nature
Languages : en
Pages : 434
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Book Description
Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.
Author: Universities Associated for Research and Education in Pathology
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 292
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Book Description
Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 836
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Book Description
Author: United States-Japan Cooperative Medical Science Program
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 304
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Book Description
Author: David B. Clayson
Publisher: CRC Press
ISBN: 1000697363
Category : Medical
Languages : en
Pages : 314
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Book Description
First Published in 1986, this two-volume set explores the methods of toxicological risk assessment. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for toxicologists and other practitioners in their respective fields.
Author: Richard G. Cornell
Publisher: CRC Press
ISBN: 1000146480
Category : Mathematics
Languages : en
Pages : 498
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Book Description
This book focuses on public health and epidemiologic aspects of cancer, and explores the sources of information concerning the frequency of occurrence of human cancer. It describes statistical methods useful in studying problems arising in the field of cancer and its concurrent development.
