Legalising Mitochondrial Donation PDF Download
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Author: Rebecca Dimond
Publisher: Springer
ISBN: 3319746456
Category : Social Science
Languages : en
Pages : 149
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Book Description
In 2015 the UK became the first country in the world to legalise mitochondrial donation, a controversial germ line reproductive technology to prevent the transmission of mitochondrial disease. Dimond and Stephens track the intense period of scientific and ethical review, public consultation and parliamentary debates preceeding the decision. They draw on stakeholder accounts and public documents to explore how patients, professionals, institutions and publics mobilised within ‘for’ and ‘against’ clusters, engaging in extensive promissory, emotional, bureaucratic, ethical, embodied and clinical labour to justify competing visions of an ethical future. They describe how this decision is the latest iteration of a UK sociotechnical imaginary in which the further liberalization of human embryo research and use is rendered legitimate and ethical through modes of consultation and permissive but strictly regulated licensing. Overall, this book presents a timely, multi-dimensional, and sociological account of a globally significant landmark in the history of human genetics, and will be relevant to those with an interest in genetics, Science, Technology and Society, the sociology of medicine, reproductive technology, and public policy debate.
Author: Rebecca Dimond
Publisher: Springer
ISBN: 3319746456
Category : Social Science
Languages : en
Pages : 149
Get Book Here
Book Description
In 2015 the UK became the first country in the world to legalise mitochondrial donation, a controversial germ line reproductive technology to prevent the transmission of mitochondrial disease. Dimond and Stephens track the intense period of scientific and ethical review, public consultation and parliamentary debates preceeding the decision. They draw on stakeholder accounts and public documents to explore how patients, professionals, institutions and publics mobilised within ‘for’ and ‘against’ clusters, engaging in extensive promissory, emotional, bureaucratic, ethical, embodied and clinical labour to justify competing visions of an ethical future. They describe how this decision is the latest iteration of a UK sociotechnical imaginary in which the further liberalization of human embryo research and use is rendered legitimate and ethical through modes of consultation and permissive but strictly regulated licensing. Overall, this book presents a timely, multi-dimensional, and sociological account of a globally significant landmark in the history of human genetics, and will be relevant to those with an interest in genetics, Science, Technology and Society, the sociology of medicine, reproductive technology, and public policy debate.
![Mitochondrial Donation Law Reform (Maeve's Law) Bill 2021 [Provisions] PDF](https://books.google.com/books/content/images/frontcover/msOnzgEACAAJ?fife=w80-h100)
Author: Australia. Parliament. Senate. Community Affairs Legislation Committee
Publisher:
ISBN: 9781760932732
Category :
Languages : en
Pages : 48
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Book Description
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309388708
Category : Medical
Languages : en
Pages : 201
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Book Description
Mitochondrial replacement techniques (MRTs) are designed to prevent the transmission of mitochondrial DNA (mtDNA) diseases from mother to child. While MRTs, if effective, could satisfy a desire of women seeking to have a genetically related child without the risk of passing on mtDNA disease, the technique raises significant ethical and social issues. It would create offspring who have genetic material from two women, something never sanctioned in humans, and would create mitochondrial changes that could be heritable (in female offspring), and therefore passed on in perpetuity. The manipulation would be performed on eggs or embryos, would affect every cell of the resulting individual, and once carried out this genetic manipulation is not reversible. Mitochondrial Replacement Techniques considers the implications of manipulating mitochondrial content both in children born to women as a result of participating in these studies and in descendants of any female offspring. This study examines the ethical and social issues related to MRTs, outlines principles that would provide a framework and foundation for oversight of MRTs, and develops recommendations to inform the Food and Drug Administration's consideration of investigational new drug applications.
Author: Dr. Hakim. K. Saboowala
Publisher: Dr.Hakim Saboowala
ISBN:
Category : Medical
Languages : en
Pages : 46
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Book Description
What you need to know about an Evolutionary Technique of “Mitochondrial Replacement Therapy(MRT)” a.k.a. “Mitochondrial Donation technique”: A Concise Review. Mitochondrial Replacement Therapy also referred to as “Mitochondrial Donation technique” pertains to the category of techniques in which the embryo possessing the nuclear DNA of the parents is subjected to the IVF procedure to have mitochondrial DNA of the donor female. In this era of advanced scientific technologies, MRT aims to treat the infecundity of the diseased females and provide them a suitable chance to have biologically related healthy offspring Mitochondrial replacement therapy (MRT) is a new form of reproductive in vitro fertilization (IVF) which works on the principle of replacing a women's abnormal mitochondrial DNA (mt-DNA) with the donor's healthy one. MRT include different techniques like: § Spindles transfer (ST), § Pronuclear transfer (PNT) or § Polar body transfer (PBT). Transmission of defective mitochondrial DNA to the next generation can also be prevented by using these approaches. The development of healthy baby free from genetic disorders and to terminate the lethal mitochondrial disorders are the chief motive of this technique. However, moral, social, and cultural objections have restricted its exploration. Therefore, it is attempted in this E-Booklet to summarize: · The various methods involved in MRT, · The global status, and · The exaggerated censure over the years which depicts a strong emphasis for social acceptance and clinical application in the world of medical science along with few relevant Illustrations for better understanding the subject at Molecular Level. …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London)
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Venki Ramakrishnan
Publisher: Basic Books
ISBN: 046509337X
Category : Biography & Autobiography
Languages : en
Pages : 290
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Book Description
A Nobel Prize-winning biologist tells the riveting story of his race to discover the inner workings of biology's most important molecule "Ramakrishnan's writing is so honest, lucid and engaging that I could not put this book down until I had read to the very end." -- Siddhartha Mukherjee, author of The Emperor of All Maladies and The Gene Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome -- an enormous molecular machine made up of a million atoms -- that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.
Author:
Publisher: Oxford University Press
ISBN: 0197616194
Category :
Languages : en
Pages : 305
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Book Description
A cutting-edge analysis of the global issues surrounding modern reproductive technologies Advances in assisted reproductive technologies have sparked global policy debates since the birth of the first so-called "test tube baby" in 1978. Today, mitochondrial replacement therapies represent the most recent advancement in assisted reproductive technologies, allowing some women with mitochondrial diseases to birth babies without those diseases. In the past decade, mitochondrial replacement therapies have captured public sentiment, reigniting debates around social views of reproductive rights and the appropriate legal and political response. Reproduction Reborn guides readers through the history and science of mitochondrial replacement therapies and the various attempts to control them. Leading experts from medicine, genetics, ethics, law, and policy explore the influence of public debate on the evolving shape of these technologies and their subsequent regulation. They highlight case studies from both developed and developing countries across the globe, including recent legislation in Australia and China. They further identify the ethical, legal, and societal norms that need to be addressed by policymakers and communities as more and more people seek to gain access to these treatments. Given the importance of reproduction in family life and cultural identity, clinicians and policymakers must understand how regulatory regimes around mitochondrial replacement therapies have evolved to illuminate the processes and challenges of governing reproduction in a fast-moving world. Informative and global in scope, Reproduction Reborn explores how advancements in assisted reproductive technologies challenge core values surrounding the rights and responsibilities of modern-day family units.
Author: Great Britain. Department of Health
Publisher:
ISBN:
Category : Mitochondrial pathology
Languages : en
Pages : 47
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Book Description
Author: Australia. Parliament. Senate. Community Affairs References Committee
Publisher:
ISBN:
Category : Mitochondrial DNA
Languages : en
Pages : 10
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Book Description
"The Senate referred the following matter to the Senate Community Affairs References Committee for inquiry and report: the science of mitochondrial donation and its ability to prevent transmission of mitochondrial disease; the safety and efficacy of these techniques, as well as ethical considerations; the status of these techniques elsewhere in the world and their relevance to Australian families; the current impact of mitochondrial disease on Australian families and the healthcare sector; consideration of changes to legal and ethical frameworks that would be required if mitochondrial donation was to be introduced in Australia; the value and impact of introducing mitochondrial donation in Australia; and other related matters" --Publisher's website.
Author: Harry Willekens
Publisher: Göttingen University Press
ISBN: 3863954254
Category : Law in general. Comparative and uniform law. Jurisprudence
Languages : en
Pages : 182
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Book Description
Who is a child’s legal mother? Must a child have exactly one mother, can it have two or three, or can it have two fathers, but no mother? Or has the concept of motherhood become obsolete and should we just talk of parenthood in a gender neutral way? Questions such as these would have appeared esoteric only a few decades ago, but as a result of new social developments (such as frequent family reconstitutions, gay and lesbian emancipation or surrogacy) and of technological innovations (such as egg and embryo donations) they have become issues in a vehement debate. The interdisciplinary contributions to this book focus on the legal definition of motherhood, on the way in which legal conceptions structure the social discourse on motherhood (and vice versa), and on the influence of legal rules on power relations between mothers, fathers, children and the state. Among the issues addressed are - the challenges to our understanding of the legal regulation of motherhood by developments in reproductive medicine; - the challenges to our understanding of the legal regulation of motherhood by parental constellations deviating from the mother-father-model (single motherhood by choice, same-gender parenthood, multiple parenthood); - the exercise of parental rights in case of parental separation and the impact of legal rules on the bargaining positions of mothers and fathers.
