Learning from Nature How to Design New Implantable Biomaterials: From Biomineralization Fundamentals to Biomimetic Materials and Processing Routes PDF Download
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Author: Rui L. Reis
Publisher: Springer Science & Business Media
ISBN: 140202648X
Category : Technology & Engineering
Languages : en
Pages : 240
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Book Description
The development of materials for any replacement or regeneration application should be based on the thorough understanding of the structure to be substituted. This is true in many fields, but particularly exigent in substitution and regeneration medicine. The demands upon the material properties largely depend on the site of application and the function it has to restore. Ideally, a replacement material should mimic the living tissue from a mechanical, chemical, biological and functional point of view. Of course this is much easier to write down than to implement in clinical practice. Mineralized tissues such as bones, tooth and shells have attracted, in the last few years, considerable interest as natural anisotropic composite structures with adequate mechanical properties. In fact, Nature is and will continue to be the best materials scientist ever. Who better than nature can design complex structures and control the intricate phenomena (processing routes) that lead to the final shape and structure (from the macro to the nano level) of living creatures? Who can combine biological and physico-chemical mechanisms in such a way that can build ideal structure-properties relationships? Who, else than Nature, can really design smart structural components that respond in-situ to exterior stimulus, being able of adapting constantly their microstructure and correspondent properties? In the described philosophy line, mineralized tissues and biomineralization processes are ideal examples to learn-from for the materials scientist of the future.
Author: Rui L. Reis
Publisher: Springer Science & Business Media
ISBN: 140202648X
Category : Technology & Engineering
Languages : en
Pages : 240
Get Book
Book Description
The development of materials for any replacement or regeneration application should be based on the thorough understanding of the structure to be substituted. This is true in many fields, but particularly exigent in substitution and regeneration medicine. The demands upon the material properties largely depend on the site of application and the function it has to restore. Ideally, a replacement material should mimic the living tissue from a mechanical, chemical, biological and functional point of view. Of course this is much easier to write down than to implement in clinical practice. Mineralized tissues such as bones, tooth and shells have attracted, in the last few years, considerable interest as natural anisotropic composite structures with adequate mechanical properties. In fact, Nature is and will continue to be the best materials scientist ever. Who better than nature can design complex structures and control the intricate phenomena (processing routes) that lead to the final shape and structure (from the macro to the nano level) of living creatures? Who can combine biological and physico-chemical mechanisms in such a way that can build ideal structure-properties relationships? Who, else than Nature, can really design smart structural components that respond in-situ to exterior stimulus, being able of adapting constantly their microstructure and correspondent properties? In the described philosophy line, mineralized tissues and biomineralization processes are ideal examples to learn-from for the materials scientist of the future.
Author: Jean-Francois Le Gall
Publisher: Springer Science & Business Media
ISBN: 9783764361266
Category : Mathematics
Languages : en
Pages : 438
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Book Description
This book introduces several remarkable new probabilistic objects that combine spatial motion with a continuous branching phenomenon and are closely related to certain semilinear partial differential equations (PDE). The Brownian snake approach is used to give a powerful representation of superprocesses and also to investigate connections between superprocesses and PDEs. These are notable because almost every important probabilistic question corresponds to a significant analytic problem.
Author: Ilaria Mazzoleni
Publisher: CRC Press
ISBN: 1040077617
Category : Science
Languages : en
Pages : 266
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Book Description
This full-color volume proposes an innovative methodology that uses the functional aspects of nature to inspire improvements in building design and form, encouraging designers to apply biomimetic principles to architectural processes. The book focuses on the analysis of various animal skins, translating the principles of communication, thermoregulation, water balance, and protection into the built environment. Illustrating how biomimetic principles can create a more sustainable way of building, this is the first time the author's new methodology-as well as the 12 case studies-has been published.
Author: Rui L. Reis
Publisher: Elsevier
ISBN: 1845694813
Category : Technology & Engineering
Languages : en
Pages : 832
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Book Description
Polymers from natural sources are particularly useful as biomaterials and in regenerative medicine, given their similarity to the extracellular matrix and other polymers in the human body. This important book reviews the wealth of research on both tried and promising new natural-based biomedical polymers, together with their applications as implantable biomaterials, controlled-release carriers or scaffolds for tissue engineering. The first part of the book reviews the sources, processing and properties of natural-based polymers for biomedical applications. Part two describes how the surfaces of polymer-based biomaterials can be modified to improve their functionality. The third part of the book discusses the use of natural-based polymers for biodegradable scaffolds and hydrogels in tissue engineering. Building on this foundation, Part four looks at the particular use of natural-gelling polymers for encapsulation, tissue engineering and regenerative medicine. The penultimate group of chapters reviews the use of natural-based polymers as delivery systems for drugs, hormones, enzymes and growth factors. The final part of the book summarises research on the key issue of biocompatibility. Natural-based polymers for biomedical applications is a standard reference for biomedical engineers, those studying and researching in this important area, and the medical community. Examines the sources, processing and properties of natural based polymers for biomedical applications Explains how the surfaces of polymer based biomaterials can be modified to improve their functionality Discusses the use of natural based polymers for hydrogels in tissue engineering, and in particular natural gelling polymers for encapsulation and regenerative medicine
Author: Conrado Aparicio
Publisher: Woodhead Publishing
ISBN: 1782423567
Category : Technology & Engineering
Languages : en
Pages : 482
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Book Description
Biomineralization is a natural process by which living organisms form minerals in association with organic biostructures to form hybrid biological materials such as bone, enamel, dentine and nacre among others. Scientists have researched the fundamentals of these processes and the unique structures and properties of the resulting mineralized tissues. Inspired by them, new biomaterials for tissue engineering and regenerative medicine have been developed in recent years. Biomineralization and biomaterials: fundamentals and applications looks at the characteristics of these essential processes and natural materials and describes strategies and technologies to biomimetically design and produce biomaterials with improved biological performance. Provides a thorough overview of the biomineralization process Presents the most recent information on the natural process by which crystals in tissues form into inorganic structures such as bone, teeth, and other natural mineralized tissues Investigates methods for improving mineralization Explores new techniques that will help improve the biomimetic process
Author: Kantesh Balani
Publisher: John Wiley & Sons
ISBN: 1118950631
Category : Technology & Engineering
Languages : en
Pages : 397
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Book Description
Ideal as a graduate textbook, this title is aimed at helping design effective biomaterials, taking into account the complex interactions that occur at the interface when a synthetic material is inserted into a living system. Surface reactivity, biochemistry, substrates, cleaning, preparation, and coatings are presented, with numerous case studies and applications throughout. Highlights include: Starts with concepts and works up to real-life applications such as implantable devices, medical devices, prosthetics, and drug delivery technology Addresses surface reactivity, requirements for surface coating, cleaning and preparation techniques, and characterization Discusses the biological response to coatings Addresses biomaterial-tissue interaction Incorporates nanomechanical properties and processing strategies
Author: Alexander E.S. Van Driessche
Publisher: Springer
ISBN: 3319456695
Category : Science
Languages : en
Pages : 380
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Book Description
In the last decade, numerous studies have demonstrated the existence of alternative pathways to nucleation and crystallisation that oppose the classical view. Such proposed scenarios include multistage reactions proceeding via various precursor species and/or intermediate phases. The aim of this book is to review and discuss these recent advances in our understanding of the early stages of mineralisation through a series of contributions that address both experimental and theoretical studies about the formation and nature of initial precursor species (e.g., prenucleation clusters, dense liquid phases, amorphous nanoparticles, etc.) as well as their transformations leading to the stable mineral phase. Several chapters are devoted to cutting-edge analytical techniques used for investigating the above processes in situ, in real time and at conditions relevant to both natural and industrial processes. At the end of the book, the editors summarize the key questions that still need to be addressed in order to establish a complete picture of the nucleation and growth processes involved during the formation of minerals
Author: Sabu Thomas
Publisher: Woodhead Publishing
ISBN: 0081022042
Category : Technology & Engineering
Languages : en
Pages : 498
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Book Description
Fundamental Biomaterials: Ceramics provides current information on ceramics and their conversion from base materials to medical devices. Initial chapters review biomedical applications and types of ceramics, with subsequent sections focusing on the properties of ceramics, and on corrosion, degradation and wear of ceramic biomaterials. The book is ideal for researchers and professionals in the development stages of design, but is also helpful to medical researchers who need to understand and communicate the requirements of a biomaterial for a specific application. This title is the second in a three volume set, with each reviewing the most important and commonly used classes of biomaterials and providing comprehensive information on material properties, behavior, biocompatibility and applications. In addition, with the recent introduction of a number of interdisciplinary bio-related undergraduate and graduate programs, this book will be an appropriate reference volume for large number of students at undergraduate and post graduate levels Provides current information on findings and developments of ceramics and their conversion from base materials to medical devices Includes analyses of the types of ceramics and a discussion of a range of biomedical applications and essential properties, including information on corrosion, degradation and wear, and lifetime prediction of ceramic biomaterials Explores both theoretical and practical aspects of ceramics in biomaterials
Author: Joao F. Mano
Publisher: John Wiley & Sons
ISBN: 3527652299
Category : Science
Languages : en
Pages : 872
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Book Description
Biomimetics, in general terms, aims at understanding biological principles and applying them for the development of man-made tools and technologies. This approach is particularly important for the purposeful design of passive as well as functional biomaterials that mimic physicochemical, mechanical and biological properties of natural materials, making them suitable, for example, for biomedical devices or as scaffolds for tissue regeneration. The book comprehensively covers biomimetic approaches to the development of biomaterials, including: an overview of naturally occurring or nature inspired biomaterials; an in-depth treatment of the surface aspects pivotal for the functionality; synthesis and self-assembly methods to prepare devices to be used in mineralized tissues such as bone and teeth; and preparation of biomaterials for the controlled/ sustained release of bioactive agents. The last part reviews the applications of bioinspired materials and principles of design in regenerative medicine such as in-situ grown bone or cartilage as well as the biomimetic techniques for soft tissue engineering. The comprehensive scope of this book makes it a must-have addition to the bookshelf of everyone in the fields of Materials Science/Engineering, Nanotechnologies / Nanosciences, Medical Sciences, Biochemistry, Polymer Chemistry, and Biomedical Engineering.
Author: Besim Ben-Nissan
Publisher: Springer Science & Business
ISBN: 3642539807
Category : Technology & Engineering
Languages : en
Pages : 559
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Book Description
Advances in Calcium Phosphate Biomaterials presents a comprehensive, state-of-the-art review of the latest advances in developing calcium phosphate biomaterials and their applications in medicine. It covers the fundamental structures, synthesis methods, characterization methods, and the physical and chemical properties of calcium phosphate biomaterials, as well as the synthesis and properties of calcium phosphate-based biomaterials in regenerative medicine and their clinical applications. The book brings together these new concepts, mechanisms and methods in contributions by both young and “veteran” academics, clinicians, and researchers to forward the knowledge and expertise on calcium phosphate and related materials. Accordingly, the book not only covers the fundamentals but also open new avenues for meeting future challenges in research and clinical applications. Besim Ben-Nissan is a Professor of Chemistry and Forensic Science at the University of Technology, Sydney, Australia
