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Author: Joseph G. Gall
Publisher: CSHL Press
ISBN: 9780879696023
Category : Cells
Languages : en
Pages : 776
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Book Description
Annotation Contains 42 seminal papers illustrating advances in cell biology, along with brief commentaries that place the papers in historical and intellectual context. All papers are studies of eukaryotes, and are grouped according to themes of genome organization and replication, transcription, nuclear envelope and nuclear import, mitosis and cell cycle control, cell membrane and extracellular matrix, protein synthesis and membrane traffic, and cytoskeleton. Lacks a subject index. Gall teaches embryology at the Carnegie Institution. McIntosh teaches cell biology at the University of Colorado. Annotation c. Book News, Inc., Portland, OR (booknews.com).
Author: Joseph G. Gall
Publisher: CSHL Press
ISBN: 9780879696023
Category : Cells
Languages : en
Pages : 776
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Book Description
Annotation Contains 42 seminal papers illustrating advances in cell biology, along with brief commentaries that place the papers in historical and intellectual context. All papers are studies of eukaryotes, and are grouped according to themes of genome organization and replication, transcription, nuclear envelope and nuclear import, mitosis and cell cycle control, cell membrane and extracellular matrix, protein synthesis and membrane traffic, and cytoskeleton. Lacks a subject index. Gall teaches embryology at the Carnegie Institution. McIntosh teaches cell biology at the University of Colorado. Annotation c. Book News, Inc., Portland, OR (booknews.com).
Author: Patrick Linder
Publisher: CSHL Press
ISBN: 0879696435
Category : Science
Languages : en
Pages : 311
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Book Description
The yeasts have been important experimental organisms for more than 50 years. This volume contains over 100 selected papers, in sections with introductions that describe the process of discovery and the context and significance of the research. The selections include early classics as well as recent advances in areas such as signal transduction, membrane trafficking, protein turnover, and genomics. This book is designed as a guide for a literature-based course.
Author: Kenneth R. Miller
Publisher: Jai Press
ISBN: 9780892328864
Category : Science
Languages : en
Pages : 307
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Book Description
As a discipline, cell biology has classically been defined by the boundaries which define the limits of its interests. These boundaries may apply to location -cell biologists study material within the cell - or they may apply to size - cell biologists study material above the level of the macromolecule. For many years, the limits of technique enforced these boundaries as surely as any custom of the discipline. Our inability to investigate structures which could not be observed or molecules which could not be detected assured that cell biology would not cross the boundaries which linked the cell to other levels of organization. As the twentieth century nears its close, however, the development of an enormous range of tools and techniques, some physical, some chemical, some biological, has changed this situation forever. Cell biology today crosses the boundary, links the molecule with the organelle, associates the cellular response with the larger organism. For some, these advances have produced a sense of consternation as it becomes increasingly difficult to define the exact distinction between a cell biologist, a biophysicist, and a molecular biologist. But for many others, the same crisis of identity is perceived as a great opportunity, an opportunity to make connections at a range of levels which integrate our knowledge of living systems in a way that the pioneers of our field could hardly have imagined. I hold to this latter view, and I suspect that nearly all of the contributors to this volume do as well. Each of the articles within this volume cross boundaries in their efforts to deal with the complexities of the living cell. As examples, the work of Carl Cohen illustrates the emergence of a new understanding of the interface between cell membrane and cytoskeleton. Robert Murphy's studies follow the movement of material into the cell and through a maze of cellular compartments, and the studies of Vivianne Nachmias and Ken-ichi Yoshida illustrate the influences exerted by a range of proteins on shape changes in platelets. Each of the studies in this volume has, in a certain sense, crossed the traditional limits of study and made an important contribution to developing a complete and dynamic picture of biology at the level of the cell. In its own way, each article points towards the ultimate goal of cell biology: an understanding in which all of the boundaries which separate organism from cell and cell from molecule will have been breached. That goal is not yet in sight, but the journey is only beginning.
Author: Harvey Lodish
Publisher: W.H. Freeman
ISBN: 9780716730538
Category :
Languages : en
Pages : 1344
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Book Description
With its acclaimed author team, cutting-edge content, emphasis on medical relevance, and coverage based on landmark experiments, "Molecular Cell Biology" has justly earned an impeccable reputation as an authoritative and exciting text. The new Sixth Edition features two new coauthors, expanded coverage of immunology and development, and new media tools for students and instructors.
Author: Michael Fry
Publisher: Academic Press
ISBN: 012802108X
Category : Science
Languages : en
Pages : 570
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Book Description
Landmark Experiments in Molecular Biology critically considers breakthrough experiments that have constituted major turning points in the birth and evolution of molecular biology. These experiments laid the foundations to molecular biology by uncovering the major players in the machinery of inheritance and biological information handling such as DNA, RNA, ribosomes, and proteins. Landmark Experiments in Molecular Biology combines an historical survey of the development of ideas, theories, and profiles of leading scientists with detailed scientific and technical analysis. Includes detailed analysis of classically designed and executed experiments Incorporates technical and scientific analysis along with historical background for a robust understanding of molecular biology discoveries Provides critical analysis of the history of molecular biology to inform the future of scientific discovery Examines the machinery of inheritance and biological information handling
Author: Robert D. Burgoyne
Publisher: Ashgate Publishing
ISBN: 9781855781016
Category : Cell interaction
Languages : en
Pages : 267
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Book Description
The intracellular signalling pathways that control cell function have been and still are, one of the most intensively studied aspects of biology. The aim of this work is to provide full reproductions of a set of key papers which have been chosen as landmark papers in the various aspects of intracellular signalling. The papers are accompanied by commentaries that describe why they are significant, how the work came about and summarize the advances that have been made up to the present time as a consequence of the original paper. The commentaries should also serve as reviews of aspects of cell regulation and may be read on their own.
Author: Reuben D. Johnson
Publisher: Landmark Papers in
ISBN: 0199674027
Category : Medical
Languages : en
Pages : 417
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Book Description
This book provides a detailed summary of the most important trials and studies in neurosurgery, allowing the reader to rapidly extract the key results of all major trials.
Author: Athena Aktipis
Publisher: Princeton University Press
ISBN: 0691163847
Category : Medical
Languages : en
Pages : 256
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Book Description
A fundamental and groundbreaking reassessment of how we view and manage cancer When we think of the forces driving cancer, we don’t necessarily think of evolution. But evolution and cancer are closely linked because the historical processes that created life also created cancer. The Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer’s evolutionary origins, researchers can come up with more effective, revolutionary treatments. Athena Aktipis goes back billions of years to explore when unicellular forms became multicellular organisms. Within these bodies of cooperating cells, cheating ones arose, overusing resources and replicating out of control, giving rise to cancer. Aktipis illustrates how evolution has paved the way for cancer’s ubiquity, and why it will exist as long as multicellular life does. Even so, she argues, this doesn’t mean we should give up on treating cancer—in fact, evolutionary approaches offer new and promising options for the disease’s prevention and treatments that aim at long-term management rather than simple eradication. Looking across species—from sponges and cacti to dogs and elephants—we are discovering new mechanisms of tumor suppression and the many ways that multicellular life-forms have evolved to keep cancer under control. By accepting that cancer is a part of our biological past, present, and future—and that we cannot win a war against evolution—treatments can become smarter, more strategic, and more humane. Unifying the latest research from biology, ecology, medicine, and social science, The Cheating Cell challenges us to rethink cancer’s fundamental nature and our relationship to it.
Author: Harvey F. Lodish
Publisher: Scientific American Library
ISBN:
Category : Cells
Languages : en
Pages : 1192
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Book Description
With its acclaimed author team, cutting-edge content, emphasis on medical relevance, and coverage based on landmark experiments, "Molecular Cell Biology" has justly earned an impeccable reputation as an authoritative and exciting text. The new Sixth Edition features two new coauthors, expanded coverage of immunology and development, and new media tools for students and instructors.
Author: Elizabeth Ryznar
Publisher: Oxford University Press
ISBN: 019253887X
Category : Medical
Languages : en
Pages : 449
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Book Description
Advances in the practice of psychiatry have occurred in "fits and starts" over the last several decades. These advances are evident to anyone long affiliated with the field and are best appreciated through direct experience of living through the times. These advances can also be gleaned from historical overviews in textbooks or the recollections of one's teachers and mentors. Returning to the original papers that have ushered in these changes is rarely done for various, mostly practical, reasons. Filtering through thousands of articles in psychiatry may prove daunting, access to the manuscripts may be limited (especially for papers not available electronically), and understanding their impact requires a broader context. Moreover, with so much active research currently occurring in various branches of psychiatry, current practitioners or trainees may find their attention focused on the present, and this is reinforced by electronic search algorithms, which return articles in reverse chronological order. Not surprisingly, citations for articles in virtually all fields decline precipitously for articles over five years old. As scholars and professionals, we are losing touch with our academic heritage. Yet navigating the future of psychiatry requires a firm understanding of its past. This resource serves as a guide for anyone seeking to understand the evolution of psychiatry as a scientific discipline. It does so by summarizing over 100 landmark papers in psychiatry and placing their scientific contributions within a historical context. An introductory section sets the stage for the major theoretical constructs within the field, with chapters devoted to ontology and nosology. Subsequent sections examine major facets of the theory and practice of psychiatry, such as pathogenesis of psychiatric illness, pharmacotherapy, psychotherapy, and somatic treatments. These sections are divided logically into chapters addressing important contributions to the understanding and treatment of specific disorders. A final section explores ethical considerations within each field. This framework echoes the complexity of psychiatry, which cannot be reduced to a single set of diagnoses or subspecialty categories. Highlighting the research trajectory of psychiatry, this resource will appeal to academics, trainees, and practitioners who desire a comprehensive, easy-to-read, up-to-date collection of psychiatry's pivotal moments. By understanding the challenges, inspirations, and insights from the past, readers will be better poised to address new and ongoing challenges within the field.
