Author: Kamil Uludag
Publisher: Springer
ISBN: 1489975918
Category : Medical
Languages : en
Pages : 926
Book Description
This volume explores the revolutionary fMRI field from basic principles to state-of-the-art research. It covers a broad spectrum of topics, including the history of fMRI's development using endogenous MR blood contrast, neurovascular coupling, pulse sequences for fMRI, quantitative fMRI; fMRI of the visual system, auditory cortex, and sensorimotor system; genetic imaging using fMRI, multimodal neuroimaging, brain bioenergetics and function and molecular-level fMRI. Comprehensive and intuitively structured, this book engages the reader with a first-person account of the development and history of the fMRI field by the authors. The subsequent sections examine the physiological basis of fMRI, the basic principles of fMRI and its applications and the latest advances of the technology, ending with a discussion of fMRI’s future. fMRI: From Nuclear Spins to Brain Function, co-edited by leading and renowned fMRI researchers Kamil Ugurbil, Kamil Uludag and Lawrence Berliner, is an ideal resource for clinicians and researchers in the fields of neuroscience, psychology and MRI physics.
fMRI: From Nuclear Spins to Brain Functions
Author: Kamil Uludag
Publisher: Springer
ISBN: 1489975918
Category : Medical
Languages : en
Pages : 926
Book Description
This volume explores the revolutionary fMRI field from basic principles to state-of-the-art research. It covers a broad spectrum of topics, including the history of fMRI's development using endogenous MR blood contrast, neurovascular coupling, pulse sequences for fMRI, quantitative fMRI; fMRI of the visual system, auditory cortex, and sensorimotor system; genetic imaging using fMRI, multimodal neuroimaging, brain bioenergetics and function and molecular-level fMRI. Comprehensive and intuitively structured, this book engages the reader with a first-person account of the development and history of the fMRI field by the authors. The subsequent sections examine the physiological basis of fMRI, the basic principles of fMRI and its applications and the latest advances of the technology, ending with a discussion of fMRI’s future. fMRI: From Nuclear Spins to Brain Function, co-edited by leading and renowned fMRI researchers Kamil Ugurbil, Kamil Uludag and Lawrence Berliner, is an ideal resource for clinicians and researchers in the fields of neuroscience, psychology and MRI physics.
Publisher: Springer
ISBN: 1489975918
Category : Medical
Languages : en
Pages : 926
Book Description
This volume explores the revolutionary fMRI field from basic principles to state-of-the-art research. It covers a broad spectrum of topics, including the history of fMRI's development using endogenous MR blood contrast, neurovascular coupling, pulse sequences for fMRI, quantitative fMRI; fMRI of the visual system, auditory cortex, and sensorimotor system; genetic imaging using fMRI, multimodal neuroimaging, brain bioenergetics and function and molecular-level fMRI. Comprehensive and intuitively structured, this book engages the reader with a first-person account of the development and history of the fMRI field by the authors. The subsequent sections examine the physiological basis of fMRI, the basic principles of fMRI and its applications and the latest advances of the technology, ending with a discussion of fMRI’s future. fMRI: From Nuclear Spins to Brain Function, co-edited by leading and renowned fMRI researchers Kamil Ugurbil, Kamil Uludag and Lawrence Berliner, is an ideal resource for clinicians and researchers in the fields of neuroscience, psychology and MRI physics.
Functional MRI
Author: Scott H. Faro
Publisher: Springer Science & Business Media
ISBN: 0387346651
Category : Medical
Languages : en
Pages : 543
Book Description
Functional magnetic resonance imaging (fMRI) measures quick, tiny metabolic changes that take place in the brain, providing the most sensitive method currently available for identifying, investigating, and monitoring brain tumors, stroke, and chronic disorders of the nervous system like multiple sclerosis, and brain abnormalities related to dementia or seizures. This overview explores experimental research design, outlines challenges and limitations of fMRI, provides a detailed neuroanatomic atlas, and describes clinical applications of fMRI in cognitive, sensory, motor, and pharmacological cases, translating research into clinical application.
Publisher: Springer Science & Business Media
ISBN: 0387346651
Category : Medical
Languages : en
Pages : 543
Book Description
Functional magnetic resonance imaging (fMRI) measures quick, tiny metabolic changes that take place in the brain, providing the most sensitive method currently available for identifying, investigating, and monitoring brain tumors, stroke, and chronic disorders of the nervous system like multiple sclerosis, and brain abnormalities related to dementia or seizures. This overview explores experimental research design, outlines challenges and limitations of fMRI, provides a detailed neuroanatomic atlas, and describes clinical applications of fMRI in cognitive, sensory, motor, and pharmacological cases, translating research into clinical application.
Handbook of MRI Pulse Sequences
Author: Matt A. Bernstein
Publisher: Elsevier
ISBN: 0080533124
Category : Mathematics
Languages : en
Pages : 1041
Book Description
Magnetic Resonance Imaging (MRI) is among the most important medical imaging techniques available today. There is an installed base of approximately 15,000 MRI scanners worldwide. Each of these scanners is capable of running many different "pulse sequences", which are governed by physics and engineering principles, and implemented by software programs that control the MRI hardware. To utilize an MRI scanner to the fullest extent, a conceptual understanding of its pulse sequences is crucial. Handbook of MRI Pulse Sequences offers a complete guide that can help the scientists, engineers, clinicians, and technologists in the field of MRI understand and better employ their scanner. - Explains pulse sequences, their components, and the associated image reconstruction methods commonly used in MRI - Provides self-contained sections for individual techniques - Can be used as a quick reference guide or as a resource for deeper study - Includes both non-mathematical and mathematical descriptions - Contains numerous figures, tables, references, and worked example problems
Publisher: Elsevier
ISBN: 0080533124
Category : Mathematics
Languages : en
Pages : 1041
Book Description
Magnetic Resonance Imaging (MRI) is among the most important medical imaging techniques available today. There is an installed base of approximately 15,000 MRI scanners worldwide. Each of these scanners is capable of running many different "pulse sequences", which are governed by physics and engineering principles, and implemented by software programs that control the MRI hardware. To utilize an MRI scanner to the fullest extent, a conceptual understanding of its pulse sequences is crucial. Handbook of MRI Pulse Sequences offers a complete guide that can help the scientists, engineers, clinicians, and technologists in the field of MRI understand and better employ their scanner. - Explains pulse sequences, their components, and the associated image reconstruction methods commonly used in MRI - Provides self-contained sections for individual techniques - Can be used as a quick reference guide or as a resource for deeper study - Includes both non-mathematical and mathematical descriptions - Contains numerous figures, tables, references, and worked example problems
Vital Models
Author:
Publisher: Academic Press
ISBN: 0128125586
Category : Medical
Languages : en
Pages : 248
Book Description
The use of models has been important to the historical and contemporary study of the human brain, yet very little study by social scientists has been dedicated to how the brain sciences develop and use models to better understand what brains are and how they work, including the complex entanglements between brains, bodies and their environments. Vital Models: The Making and Use of Models in the Brain Sciences explores the history and use of brain models from clinical psychiatry to psychopharmacology and cybernetics, as well as developments in digital brain modeling, simulation, imaging and connectomics. This timely volume helps both scientists and students better understand the variety, strengths, weaknesses and applicability of models in neuroscience. - Presents a timely update on the topic of brain research and modeling techniques - Contains sections from true authorities in the field
Publisher: Academic Press
ISBN: 0128125586
Category : Medical
Languages : en
Pages : 248
Book Description
The use of models has been important to the historical and contemporary study of the human brain, yet very little study by social scientists has been dedicated to how the brain sciences develop and use models to better understand what brains are and how they work, including the complex entanglements between brains, bodies and their environments. Vital Models: The Making and Use of Models in the Brain Sciences explores the history and use of brain models from clinical psychiatry to psychopharmacology and cybernetics, as well as developments in digital brain modeling, simulation, imaging and connectomics. This timely volume helps both scientists and students better understand the variety, strengths, weaknesses and applicability of models in neuroscience. - Presents a timely update on the topic of brain research and modeling techniques - Contains sections from true authorities in the field
Magnetic Resonance Imaging
Author: Robert W. Brown
Publisher: John Wiley & Sons
ISBN: 0471720852
Category : Medical
Languages : en
Pages : 976
Book Description
New edition explores contemporary MRI principles and practices Thoroughly revised, updated and expanded, the second edition of Magnetic Resonance Imaging: Physical Principles and Sequence Design remains the preeminent text in its field. Using consistent nomenclature and mathematical notations throughout all the chapters, this new edition carefully explains the physical principles of magnetic resonance imaging design and implementation. In addition, detailed figures and MR images enable readers to better grasp core concepts, methods, and applications. Magnetic Resonance Imaging, Second Edition begins with an introduction to fundamental principles, with coverage of magnetization, relaxation, quantum mechanics, signal detection and acquisition, Fourier imaging, image reconstruction, contrast, signal, and noise. The second part of the text explores MRI methods and applications, including fast imaging, water-fat separation, steady state gradient echo imaging, echo planar imaging, diffusion-weighted imaging, and induced magnetism. Lastly, the text discusses important hardware issues and parallel imaging. Readers familiar with the first edition will find much new material, including: New chapter dedicated to parallel imaging New sections examining off-resonance excitation principles, contrast optimization in fast steady-state incoherent imaging, and efficient lower-dimension analogues for discrete Fourier transforms in echo planar imaging applications Enhanced sections pertaining to Fourier transforms, filter effects on image resolution, and Bloch equation solutions when both rf pulse and slice select gradient fields are present Valuable improvements throughout with respect to equations, formulas, and text New and updated problems to test further the readers' grasp of core concepts Three appendices at the end of the text offer review material for basic electromagnetism and statistics as well as a list of acquisition parameters for the images in the book. Acclaimed by both students and instructors, the second edition of Magnetic Resonance Imaging offers the most comprehensive and approachable introduction to the physics and the applications of magnetic resonance imaging.
Publisher: John Wiley & Sons
ISBN: 0471720852
Category : Medical
Languages : en
Pages : 976
Book Description
New edition explores contemporary MRI principles and practices Thoroughly revised, updated and expanded, the second edition of Magnetic Resonance Imaging: Physical Principles and Sequence Design remains the preeminent text in its field. Using consistent nomenclature and mathematical notations throughout all the chapters, this new edition carefully explains the physical principles of magnetic resonance imaging design and implementation. In addition, detailed figures and MR images enable readers to better grasp core concepts, methods, and applications. Magnetic Resonance Imaging, Second Edition begins with an introduction to fundamental principles, with coverage of magnetization, relaxation, quantum mechanics, signal detection and acquisition, Fourier imaging, image reconstruction, contrast, signal, and noise. The second part of the text explores MRI methods and applications, including fast imaging, water-fat separation, steady state gradient echo imaging, echo planar imaging, diffusion-weighted imaging, and induced magnetism. Lastly, the text discusses important hardware issues and parallel imaging. Readers familiar with the first edition will find much new material, including: New chapter dedicated to parallel imaging New sections examining off-resonance excitation principles, contrast optimization in fast steady-state incoherent imaging, and efficient lower-dimension analogues for discrete Fourier transforms in echo planar imaging applications Enhanced sections pertaining to Fourier transforms, filter effects on image resolution, and Bloch equation solutions when both rf pulse and slice select gradient fields are present Valuable improvements throughout with respect to equations, formulas, and text New and updated problems to test further the readers' grasp of core concepts Three appendices at the end of the text offer review material for basic electromagnetism and statistics as well as a list of acquisition parameters for the images in the book. Acclaimed by both students and instructors, the second edition of Magnetic Resonance Imaging offers the most comprehensive and approachable introduction to the physics and the applications of magnetic resonance imaging.
The Claustrum
Author: John R. Smythies
Publisher: Academic Press
ISBN: 012404722X
Category : Medical
Languages : en
Pages : 408
Book Description
The present day is witnessing an explosion of our understanding of how the brain works at all levels, in which complexity is piled on complexity, and mechanisms of astonishing elegance are being continually discovered. This process is most developed in the major areas of the brain, such as the cortex, thalamus, and striatum. The Claustrum instead focuses on a small, remote, and, until recently, relatively unknown area of the brain. In recent years, researchers have come to believe that the claustrum is concerned with consciousness, a bold hypothesis supported by the claustrum's two-way connections with nearly every other region of the brain and its seeming involvement with multisensory integrations—the hallmark of consciousness. The claustrum, previously in a humble position at the back of the stage, might in fact be the conductor of the brain's orchestra. The Claustrum brings together leading experts on the claustrum from the varied disciplines of neuroscience, providing a state-of-the-art presentation of what is currently known about the claustrum, promising lines of current research (including epigenetics), and projections of new lines of investigation on the horizon. - Develops a unifying hypothesis about the claustrum's role in consciousness, as well as the integration of sensory information and other higher brain functions - Discusses the involvement of the claustrum with autism, schizophrenia, epilepsy, Alzheimer's disease, and Parkinson's disease - Coverage of all aspects of the claustrum, from its evolution and development to promising new lines of research, including epigenetics, provides a platform and point of reference for future investigative efforts
Publisher: Academic Press
ISBN: 012404722X
Category : Medical
Languages : en
Pages : 408
Book Description
The present day is witnessing an explosion of our understanding of how the brain works at all levels, in which complexity is piled on complexity, and mechanisms of astonishing elegance are being continually discovered. This process is most developed in the major areas of the brain, such as the cortex, thalamus, and striatum. The Claustrum instead focuses on a small, remote, and, until recently, relatively unknown area of the brain. In recent years, researchers have come to believe that the claustrum is concerned with consciousness, a bold hypothesis supported by the claustrum's two-way connections with nearly every other region of the brain and its seeming involvement with multisensory integrations—the hallmark of consciousness. The claustrum, previously in a humble position at the back of the stage, might in fact be the conductor of the brain's orchestra. The Claustrum brings together leading experts on the claustrum from the varied disciplines of neuroscience, providing a state-of-the-art presentation of what is currently known about the claustrum, promising lines of current research (including epigenetics), and projections of new lines of investigation on the horizon. - Develops a unifying hypothesis about the claustrum's role in consciousness, as well as the integration of sensory information and other higher brain functions - Discusses the involvement of the claustrum with autism, schizophrenia, epilepsy, Alzheimer's disease, and Parkinson's disease - Coverage of all aspects of the claustrum, from its evolution and development to promising new lines of research, including epigenetics, provides a platform and point of reference for future investigative efforts
MR Spectroscopy of Pediatric Brain Disorders
Author: Stefan Blüml
Publisher: Springer Science & Business Media
ISBN: 1441958649
Category : Medical
Languages : en
Pages : 405
Book Description
Magnetic resonance spectroscopy (MRS) is a modality available on most clinical MR scanners and readily integrated with standard MR imaging (MRI). For the brain in particular, MRS has been a powerful research tool providing additional clinically relevant information for several disease families such as brain tumors, metabolic disorders, and systemic diseases. The most widely-available MRS method, proton (1H; hydrogen) spectroscopy, is FDA approved for general use in the US and can be ordered by clinicians for patient studies if indicated. There are several books available that describe applications of MRS in adults. However, to the best of our knowledge there is currently no book available that focuses exclusively on applications in pediatrics. MR spectroscopy in the pediatric population is different from adults for two main reasons. Particularly in the newborn phase the brain undergoes biochemical maturation with dramatic changes of the "normal" biochemical fingerprint. Secondly, brain diseases in the pediatric population are different from adult disorders. For example, brain tumors, which are mostly gliomas in the adults, often originate from different cell types and are also more diverse even within the same type and grade of tumor. This diversity of diseases and its implications for MR spectroscopy has not been addressed sufficiently in the literature, we believe. The target audience for "MR Spectroscopy of Pediatric Brain Disorders" are thus both clinicians and researchers involved with pediatric brain disorders. This includes radiologists, neurologists, neurooncologists, neurosurgeons, and more broadly the neuroscience and neurobiology community. This book will provide the necessary background information to understand the basics of MR spectroscopy. This will be followed by a detailed discussion of the normal biochemical maturation which will highlight the metabolic differences between the pediatric and adult brain. Thereafter, in SECTION I individual chapters will address various pediatric brain disease families. Of particular importance for pediatrics are case studies. For that reason, SECTION II will contain a large number of case studies. This will be particularly important for clinicians who may want to see examples of MRS for various conditions. A standardized format will be used for case reports that allow the reader to quickly understand the history of each case presented and the significance of the findings. The case reports will also include information from other imaging modalities to point out any added value of MRS in addition to conventional studies and clinical information. This section is necessary because the format of providing more complete information about individual patients is not practical for the chapters in SECTION I.
Publisher: Springer Science & Business Media
ISBN: 1441958649
Category : Medical
Languages : en
Pages : 405
Book Description
Magnetic resonance spectroscopy (MRS) is a modality available on most clinical MR scanners and readily integrated with standard MR imaging (MRI). For the brain in particular, MRS has been a powerful research tool providing additional clinically relevant information for several disease families such as brain tumors, metabolic disorders, and systemic diseases. The most widely-available MRS method, proton (1H; hydrogen) spectroscopy, is FDA approved for general use in the US and can be ordered by clinicians for patient studies if indicated. There are several books available that describe applications of MRS in adults. However, to the best of our knowledge there is currently no book available that focuses exclusively on applications in pediatrics. MR spectroscopy in the pediatric population is different from adults for two main reasons. Particularly in the newborn phase the brain undergoes biochemical maturation with dramatic changes of the "normal" biochemical fingerprint. Secondly, brain diseases in the pediatric population are different from adult disorders. For example, brain tumors, which are mostly gliomas in the adults, often originate from different cell types and are also more diverse even within the same type and grade of tumor. This diversity of diseases and its implications for MR spectroscopy has not been addressed sufficiently in the literature, we believe. The target audience for "MR Spectroscopy of Pediatric Brain Disorders" are thus both clinicians and researchers involved with pediatric brain disorders. This includes radiologists, neurologists, neurooncologists, neurosurgeons, and more broadly the neuroscience and neurobiology community. This book will provide the necessary background information to understand the basics of MR spectroscopy. This will be followed by a detailed discussion of the normal biochemical maturation which will highlight the metabolic differences between the pediatric and adult brain. Thereafter, in SECTION I individual chapters will address various pediatric brain disease families. Of particular importance for pediatrics are case studies. For that reason, SECTION II will contain a large number of case studies. This will be particularly important for clinicians who may want to see examples of MRS for various conditions. A standardized format will be used for case reports that allow the reader to quickly understand the history of each case presented and the significance of the findings. The case reports will also include information from other imaging modalities to point out any added value of MRS in addition to conventional studies and clinical information. This section is necessary because the format of providing more complete information about individual patients is not practical for the chapters in SECTION I.
Statistical Parametric Mapping: The Analysis of Functional Brain Images
Author: William D. Penny
Publisher: Elsevier
ISBN: 0080466508
Category : Psychology
Languages : en
Pages : 689
Book Description
In an age where the amount of data collected from brain imaging is increasing constantly, it is of critical importance to analyse those data within an accepted framework to ensure proper integration and comparison of the information collected. This book describes the ideas and procedures that underlie the analysis of signals produced by the brain. The aim is to understand how the brain works, in terms of its functional architecture and dynamics. This book provides the background and methodology for the analysis of all types of brain imaging data, from functional magnetic resonance imaging to magnetoencephalography. Critically, Statistical Parametric Mapping provides a widely accepted conceptual framework which allows treatment of all these different modalities. This rests on an understanding of the brain's functional anatomy and the way that measured signals are caused experimentally. The book takes the reader from the basic concepts underlying the analysis of neuroimaging data to cutting edge approaches that would be difficult to find in any other source. Critically, the material is presented in an incremental way so that the reader can understand the precedents for each new development. This book will be particularly useful to neuroscientists engaged in any form of brain mapping; who have to contend with the real-world problems of data analysis and understanding the techniques they are using. It is primarily a scientific treatment and a didactic introduction to the analysis of brain imaging data. It can be used as both a textbook for students and scientists starting to use the techniques, as well as a reference for practicing neuroscientists. The book also serves as a companion to the software packages that have been developed for brain imaging data analysis. - An essential reference and companion for users of the SPM software - Provides a complete description of the concepts and procedures entailed by the analysis of brain images - Offers full didactic treatment of the basic mathematics behind the analysis of brain imaging data - Stands as a compendium of all the advances in neuroimaging data analysis over the past decade - Adopts an easy to understand and incremental approach that takes the reader from basic statistics to state of the art approaches such as Variational Bayes - Structured treatment of data analysis issues that links different modalities and models - Includes a series of appendices and tutorial-style chapters that makes even the most sophisticated approaches accessible
Publisher: Elsevier
ISBN: 0080466508
Category : Psychology
Languages : en
Pages : 689
Book Description
In an age where the amount of data collected from brain imaging is increasing constantly, it is of critical importance to analyse those data within an accepted framework to ensure proper integration and comparison of the information collected. This book describes the ideas and procedures that underlie the analysis of signals produced by the brain. The aim is to understand how the brain works, in terms of its functional architecture and dynamics. This book provides the background and methodology for the analysis of all types of brain imaging data, from functional magnetic resonance imaging to magnetoencephalography. Critically, Statistical Parametric Mapping provides a widely accepted conceptual framework which allows treatment of all these different modalities. This rests on an understanding of the brain's functional anatomy and the way that measured signals are caused experimentally. The book takes the reader from the basic concepts underlying the analysis of neuroimaging data to cutting edge approaches that would be difficult to find in any other source. Critically, the material is presented in an incremental way so that the reader can understand the precedents for each new development. This book will be particularly useful to neuroscientists engaged in any form of brain mapping; who have to contend with the real-world problems of data analysis and understanding the techniques they are using. It is primarily a scientific treatment and a didactic introduction to the analysis of brain imaging data. It can be used as both a textbook for students and scientists starting to use the techniques, as well as a reference for practicing neuroscientists. The book also serves as a companion to the software packages that have been developed for brain imaging data analysis. - An essential reference and companion for users of the SPM software - Provides a complete description of the concepts and procedures entailed by the analysis of brain images - Offers full didactic treatment of the basic mathematics behind the analysis of brain imaging data - Stands as a compendium of all the advances in neuroimaging data analysis over the past decade - Adopts an easy to understand and incremental approach that takes the reader from basic statistics to state of the art approaches such as Variational Bayes - Structured treatment of data analysis issues that links different modalities and models - Includes a series of appendices and tutorial-style chapters that makes even the most sophisticated approaches accessible
Introduction to Functional Magnetic Resonance Imaging
Author: Richard B. Buxton
Publisher: Cambridge University Press
ISBN: 1139481304
Category : Medical
Languages : en
Pages : 479
Book Description
Functional Magnetic Resonance Imaging (fMRI) has become a standard tool for mapping the working brain's activation patterns, both in health and in disease. It is an interdisciplinary field and crosses the borders of neuroscience, psychology, psychiatry, radiology, mathematics, physics and engineering. Developments in techniques, procedures and our understanding of this field are expanding rapidly. In this second edition of Introduction to Functional Magnetic Resonance Imaging, Richard Buxton – a leading authority on fMRI – provides an invaluable guide to how fMRI works, from introducing the basic ideas and principles to the underlying physics and physiology. He covers the relationship between fMRI and other imaging techniques and includes a guide to the statistical analysis of fMRI data. This book will be useful both to the experienced radiographer, and the clinician or researcher with no previous knowledge of the technology.
Publisher: Cambridge University Press
ISBN: 1139481304
Category : Medical
Languages : en
Pages : 479
Book Description
Functional Magnetic Resonance Imaging (fMRI) has become a standard tool for mapping the working brain's activation patterns, both in health and in disease. It is an interdisciplinary field and crosses the borders of neuroscience, psychology, psychiatry, radiology, mathematics, physics and engineering. Developments in techniques, procedures and our understanding of this field are expanding rapidly. In this second edition of Introduction to Functional Magnetic Resonance Imaging, Richard Buxton – a leading authority on fMRI – provides an invaluable guide to how fMRI works, from introducing the basic ideas and principles to the underlying physics and physiology. He covers the relationship between fMRI and other imaging techniques and includes a guide to the statistical analysis of fMRI data. This book will be useful both to the experienced radiographer, and the clinician or researcher with no previous knowledge of the technology.
Microstructural Parcellation of the Human Cerebral Cortex
Author: Stefan Geyer
Publisher: Springer Science & Business Media
ISBN: 3642378242
Category : Medical
Languages : en
Pages : 260
Book Description
Unraveling the functional properties of structural elements in the brain is one of the fundamental goals of neuroscientific research. In the cerebral cortex this is no mean feat, since cortical areas are defined microstructurally in post-mortem brains but functionally in living brains with electrophysiological or neuroimaging techniques – and cortical areas vary in their topographical properties across individual brains. Being able to map both microstructure and function in the same brains noninvasively in vivo would represent a huge leap forward. In recent years, high-field magnetic resonance imaging (MRI) technologies with spatial resolution below 0.5 mm have set the stage for this by detecting structural differences within the human cerebral cortex, beyond the Stria of Gennari. This provides the basis for an in vivo microanatomical brain map, with the enormous potential to make direct correlations between microstructure and function in living human brains. This book starts with Brodmann’s post-mortem map published in the early 20th century, moves on to the almost forgotten microstructural maps of von Economo and Koskinas and the Vogt-Vogt school, sheds some light on more recent approaches that aim at mapping cortical areas noninvasively in living human brains, and culminates with the concept of “in vivo Brodmann mapping” using high-field MRI, which was introduced in the early 21st century.
Publisher: Springer Science & Business Media
ISBN: 3642378242
Category : Medical
Languages : en
Pages : 260
Book Description
Unraveling the functional properties of structural elements in the brain is one of the fundamental goals of neuroscientific research. In the cerebral cortex this is no mean feat, since cortical areas are defined microstructurally in post-mortem brains but functionally in living brains with electrophysiological or neuroimaging techniques – and cortical areas vary in their topographical properties across individual brains. Being able to map both microstructure and function in the same brains noninvasively in vivo would represent a huge leap forward. In recent years, high-field magnetic resonance imaging (MRI) technologies with spatial resolution below 0.5 mm have set the stage for this by detecting structural differences within the human cerebral cortex, beyond the Stria of Gennari. This provides the basis for an in vivo microanatomical brain map, with the enormous potential to make direct correlations between microstructure and function in living human brains. This book starts with Brodmann’s post-mortem map published in the early 20th century, moves on to the almost forgotten microstructural maps of von Economo and Koskinas and the Vogt-Vogt school, sheds some light on more recent approaches that aim at mapping cortical areas noninvasively in living human brains, and culminates with the concept of “in vivo Brodmann mapping” using high-field MRI, which was introduced in the early 21st century.