Interstitial Hyperthermia: Physics, Biology and Clinical Aspects

Interstitial Hyperthermia: Physics, Biology and Clinical Aspects PDF Author: M. Urano
Publisher: CRC Press
ISBN: 1466564822
Category : Medical
Languages : en
Pages : 362

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Book Description
In the last decade the use of interstitial microwave antennas to deliver localized and controlled power to deep-seated tumours has been explored in institutes around the world. Simultaneously the field of brachytherapy also progressed as clinicans began to develop new implantation approaches for a variety of tumour sites, thereby promoting the insertion of catheters which could serve as conduits for the insterstitial microwave applicators. Although the challenges presented by deep-seated tumours have not been solved, the developments in the field of brachytherapy and the implantation of interstitial applicators for hyperthermia are such that a volume dedicated to this approach is warranted. This third volume in the series "Hyperthermia and Oncology" provides insight in and updated information on various aspects of interstitial hyperthermia. It aims to serve as a guide for clinicians who are either already working in the field or who wish to implement this treatment. It also provides basic aspects to physicists and biologists who are interested in the field of hyperthermic treatment.

Interstitial Hyperthermia: Physics, Biology and Clinical Aspects

Interstitial Hyperthermia: Physics, Biology and Clinical Aspects PDF Author: M. Urano
Publisher: CRC Press
ISBN: 1466564822
Category : Medical
Languages : en
Pages : 362

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Book Description
In the last decade the use of interstitial microwave antennas to deliver localized and controlled power to deep-seated tumours has been explored in institutes around the world. Simultaneously the field of brachytherapy also progressed as clinicans began to develop new implantation approaches for a variety of tumour sites, thereby promoting the insertion of catheters which could serve as conduits for the insterstitial microwave applicators. Although the challenges presented by deep-seated tumours have not been solved, the developments in the field of brachytherapy and the implantation of interstitial applicators for hyperthermia are such that a volume dedicated to this approach is warranted. This third volume in the series "Hyperthermia and Oncology" provides insight in and updated information on various aspects of interstitial hyperthermia. It aims to serve as a guide for clinicians who are either already working in the field or who wish to implement this treatment. It also provides basic aspects to physicists and biologists who are interested in the field of hyperthermic treatment.

Biological, Physical and Clinical Aspects of Hyperthermia

Biological, Physical and Clinical Aspects of Hyperthermia PDF Author: Bhudatt R. Paliwal
Publisher: American Institute of Physics
ISBN:
Category : Medical
Languages : en
Pages : 506

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Book Description
While the establishment of hyperthermia as a routine therapy awaits the results of ongoing controlled clinical trials, the advancement in biological sciences, physics and engineering, clinical physics and dosimetry, as well as clinical implementation continues to make advances. A first attempt to document these advances was made by Dr. Gilbert H. Nussbaum in the Medical Physics Monograph No. 8 of the American Association of Physicists in Medicine, published by the American Institute of Physics in 1982. This monograph is an extension of the above work. The material is divided into six catagories: Hyperthermia Biology, Physics and Engineering, Clinical Physics, Dosimetry and Modeling, Analysis of Clinical Results, and Quality Assurance. There are numerous methods of inducing hyperthermia and there are also equally numerous clinical strategies as expected in an experimental modality. A conscious effort has been made to document the basic information and thus provide an objective learning tool. The material contained herein will be of interest to biologists, physicists, engineers, and physicians who are actively involved in the field of hyperthermia, as well as to those who are anxious to learn about this new field. Some sections provide extremely practical information needed in the routine delivery of treatments and, therefore, will be of benefit to nurses and technologists. We also believe that this material provides insight and guidance for future research.

An Introduction to the Practical Aspects of Clinical Hyperthermia

An Introduction to the Practical Aspects of Clinical Hyperthermia PDF Author: Stanley B. Field
Publisher: Taylor & Francis Group
ISBN:
Category : Medical
Languages : en
Pages : 600

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Book Description
Hyperthermia combined with either radiation or chemotherapy is rapidly becoming a clinical reality in many institutions as a form of treatment of malignant disease. This is an introduction to the subject aimed at the total audience, but particularly clinicians.

Whole Body Hyperthermia: Biological and Clinical Aspects

Whole Body Hyperthermia: Biological and Clinical Aspects PDF Author: Michel Gautherie
Publisher: Springer Science & Business Media
ISBN: 3642845967
Category : Medical
Languages : en
Pages : 218

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Book Description
1. 1 Background neoplastic diseases which are currently refractory to conventional therapy. All aspects of both preclinical Anticancer effects of elevated (noncauterizing) tem and clinical WBH, ranging from molecular biology perature were first observed in ancient Egyptian times and physiology to WBH methodologies and clinical (Oleson and Dewhirst 1983). Hippocrates trials, will be comprehensively reviewed. It is our in (460-377 B. C. ) later incorporated fever therapy into a tention to provide the reader with a definitive resource homeopathic approach to disease (Le. , treating a dis of to evaluate the current status and future potential ease with a symptom of that disease). In the fourth WBH. In so doing, we will attempt to present the vari century, Refus of Ephesus advocated the use of fever ous perspectives and insights derived from the efforts induction to treat malignant diseases (Kluger 1980). of investigators throughout the world. We hope this In the nineteenth century tumor regressions accompa will encourage an expanded investigative commitment nying high fevers were reported both by Busch and to this exciting and innovative approach to cancer Bruns (Busch 1866; Bruns 1888). At the end of the therapy.

Clinical Aspects of Hyperthermia, Including Physics, Radiobiology and Radiotherapy

Clinical Aspects of Hyperthermia, Including Physics, Radiobiology and Radiotherapy PDF Author: British Institute of Radiology
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description


Physical Aspects of Hyperthermia

Physical Aspects of Hyperthermia PDF Author: Gilbert H. Nussbaum
Publisher: American Institute of Physics
ISBN: 9780883184141
Category : Science
Languages : en
Pages : 0

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Book Description
Over the past several years, interest and activity regarding the use of heat to treat human malignancies has grown very rapidly. Laboratory studies with cells and animals have established the potential of hyperthermia, used alone, or in combination with radiation or drugs, for improvement of the therapeutic ratio in cancer therapy. A growing body of clinical data suggests that hyperthermia, employed as an adjuvant and perhaps, as a primary therapeutic modality, can often effect rapid and substantial tumor regression while causing only relatively modest changes in adjacent normal tissues. Given the clinical observations to date and the rationale provided by biological and physiological laboratory investigations, the current, prodigious growth of clinical utilization of hyperthermia in surgical, medical and especially radiation oncology is not difficult to comprehend. However, the development of clinical hyperthermia as a safe, effective and quantitative cancer modality will depend critically on the extent to which the physics and physiology of local, regional and whole body heating of human tissue are understood and properly incorporated into the planning and administration of thermotherapy. Whatever its promise, ultimately, the value of hyperthermia as a clinical tool will be governed, and perhaps limited by the physical aspects of power deposition, heat transfer and thermometry in vivo. This book discusses this important topic in depth.

Consensus on Hyperthermia for the 1990s

Consensus on Hyperthermia for the 1990s PDF Author: Haim I. Bicher
Publisher: Springer Science & Business Media
ISBN: 1468457667
Category : Medical
Languages : en
Pages : 545

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Book Description
Hyperthermia as a safe and effective cancer treatment modality is rapidly evolving propelled by widespread research and clinical efforts worldwide. Presentations on Hyperthermia experience are now commonplace at Oncology meetings, as are congresses dedicated entirely to the intertwined interactions between basic sciences and patient treatment that together are forming the structure of a new medical specialty. Such was the XII International Symposium on Clinical Hyperthermia held in Rome, Italy, April 27 - 29, 1989. Papers presented therein constitute the backbone of this book. Biology research has provided data describing mechanisms of action for the cancer cell killing and physiological effects of Hyperthermia. Physics research has led to the development of equipment enabling treatment of many areas of the human body, as well as explained the limitations that still constrain our ability to treat, especially in the areas of deep seated tumor heating and non-invasive thermometry. The main question that will decide the future of this modality is that of its clinical use. To put it succinctly, what do we do with this potentially useful tool in an everyday clinical oncological practice . •• ? This is the main question addressed in this book as "Consensus on Hyperthermia for the 1990s. " The book in cludes 28 presented papers and 25 invited chapters from some of the leading experts in the field. Their basic mechanisms of action were physics principles, treatment quality assurance and especially, clinical indications.

Physics of Thermal Therapy

Physics of Thermal Therapy PDF Author: Eduardo Moros
Publisher: CRC Press
ISBN: 1439848904
Category : Medical
Languages : en
Pages : 383

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Book Description
The field of thermal therapy has been growing tenaciously in the last few decades. The application of heat to living tissues, from mild hyperthermia to high-temperature thermal ablation, has produced a host of well-documented genetic, cellular, and physiological responses that are being researched intensely for medical applications, particularly for treatment of solid cancerous tumors using image guidance. The controlled application of thermal energy to living tissues has proven a great challenge, requiring expertise from multiple disciplines, thereby leading to the development of many sophisticated pre-clinical and clinical devices and treatment techniques. Physics of Thermal Therapy: Fundamentals and Clinical Applications captures the breadth and depth of this highly multidisciplinary field. Focusing on applications in cancer treatment, this book covers basic principles, practical aspects, and clinical applications of thermal therapy. An overview of the fundamentals shows how use of controlled heat in medicine and biology involves electromagnetics, acoustics, thermodynamics, heat transfer, and imaging sciences. The book discusses challenges in the use of thermal energy on living tissues and explores the genetic, cellular, and physiological responses that can be employed in the fight against cancer from the physics and engineering perspectives. It also highlights recent advances, including the treatment of solid tumors using image-guided thermal therapy, microbubbles, nanoparticles, and other cutting-edge techniques.

Whole Body Hyperthermia

Whole Body Hyperthermia PDF Author: H I Robins
Publisher:
ISBN: 9783642845970
Category :
Languages : en
Pages : 96

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Book Description


Hyperthermia

Hyperthermia PDF Author: North American Hyperthermia Group. Meeting
Publisher: Springer
ISBN:
Category : Medical
Languages : en
Pages : 216

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Book Description
Hyperthermia is rapidly becoming the fourth modality of cancer treatment, at least a useful adjuvant to radiation therapy, chemotherapy or surgery; at best, a new therapeutic form that, properly used, may open new horizons in the fight against this dreadful disease. The staging is still primitive. The devices used are after laboratory improvisations, and lack the precision and definition of treatment fields that will allow mass use of the modality. Clinical practices are limited to the procedural evaluations of a few pioneer groups, and basic understanding of its mechanism of action, although progressing by leaps and bounds is still short of perfection. The challenge and the promise are there, and because of this, engineers, physicists, biologists, physiologists and clinicians from different specialties have a basic need for interaction, both in terms of exchange of scientific information and peer review of results and clinical trials. To satisfy this need, to act as a clearinghouse of knowledge and a forum for discussion, the North American Hyperthermia Group (NAHG) has been formed. The meeting in Detroit in August 1981 represents the first gathering of the group, to be followed by a second in Salt Lake City in April 1982. The Detroit meeting was mostly devoted to the physiology and clinical problems associated with Hyperthermia, although physics and basic thermobiology were also discussed. 75 scientists attended the meeting and 30 papers were presented. A selection of these papers represents this volume, offered more as a statement of problems than a final solution to them.