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Author: Wolfgang Walz
Publisher: Springer Science & Business Media
ISBN: 1592599257
Category : Medical
Languages : en
Pages : 271
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Book Description
There is a perception in the scientific community that the discipline of Physiology is in crisis, or at least, in a phase of profound transition and change. At the root of the problem is confusion between objectives (the biological questions to be solved) and the methods and technologies to be applied. Traditionally, ever since Claude Bernard’s concept of the “milieu interieur,” Physiology was an integrative science with the prime concern of studying regulatory mechanisms leading to adaptation and homeostasis in the presence of challenges from a dynamic internal and external environment. This study of control mechanisms can be applied on any level of fu- tion whether subcellular, cellular, and organ, but reaches its highest level of complexity with the functioning of the body as a whole and its interaction with the external environment. This involves the determination of the interaction of genetic with environmental factors and the resulting integrated body adaptation. It might seem obvious that in the pursuit of these questions any appropriate combination of techniques on any organizational level could be used. Yet the advent of molecular techniques has resulted in a preoccupation with the problems and challenges inherent in these techniques, sometimes at the expense of the original perspectives and concepts. The many new mechanisms that have been discovered at the molecular level, as well as their economical exploitation, have contributed to a climate of reductionism.
Author: Wolfgang Walz
Publisher: Springer Science & Business Media
ISBN: 1592599257
Category : Medical
Languages : en
Pages : 271
Get Book Here
Book Description
There is a perception in the scientific community that the discipline of Physiology is in crisis, or at least, in a phase of profound transition and change. At the root of the problem is confusion between objectives (the biological questions to be solved) and the methods and technologies to be applied. Traditionally, ever since Claude Bernard’s concept of the “milieu interieur,” Physiology was an integrative science with the prime concern of studying regulatory mechanisms leading to adaptation and homeostasis in the presence of challenges from a dynamic internal and external environment. This study of control mechanisms can be applied on any level of fu- tion whether subcellular, cellular, and organ, but reaches its highest level of complexity with the functioning of the body as a whole and its interaction with the external environment. This involves the determination of the interaction of genetic with environmental factors and the resulting integrated body adaptation. It might seem obvious that in the pursuit of these questions any appropriate combination of techniques on any organizational level could be used. Yet the advent of molecular techniques has resulted in a preoccupation with the problems and challenges inherent in these techniques, sometimes at the expense of the original perspectives and concepts. The many new mechanisms that have been discovered at the molecular level, as well as their economical exploitation, have contributed to a climate of reductionism.
Author: Wolfgang Walz
Publisher: Springer Science & Business Media
ISBN: 1588293157
Category : Medical
Languages : en
Pages : 271
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Book Description
The advent of molecular techniques has shifted the focus of physiology from its traditional role as an integrative science concerned with the study of regulatory mechanisms leading to adaptation and homeostasis, to a field preoccupied with the problems and challenges inherent in those techniques. In Integrative Physiology in the Proteomics and Post-Genomics Age, internationally recognized researchers highlight the major questions and accomplishments of modern physiological research and demonstrate that modern molecular methods can well be incorporated and strengthen the original integrative perspectives of physiology set out by Claude Bernard's concept of the "milieu interieur." Among the critical issues discussed are the place of functional genomics in regulatory physiology, the role of model systems in integrative physiology, the function of neural circuits in behavior and consciousness, and the influence of external challenges to the whole body and the environment on genes. The question of integrative physiology in curriculum design for the health sciences is also discussed. Perceptive and timely, Integrative Physiology in the Proteomics and Post-Genomics Age bridges the gap between molecular biology and whole body function, establishing the future of physiology as an integrative science based on new molecular insights.
Author: Michael Hehenberger
Publisher: CRC Press
ISBN: 1000292142
Category : Medical
Languages : en
Pages : 413
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Book Description
This book covers the many ways humans benefit from interactions with other living species. By studying animals of all kinds and sizes, from microbial organisms to elephants and whales, we can learn about their adaptations to extreme conditions on the planet Earth, about the evolutionary development of specialized capabilities, and about their ways to defend themselves against predators and diseases. The authors discuss the strengths and weaknesses of Homo sapiens, and how the study of animals can make us stronger and healthier. To deepen our knowledge of genetics, molecular and cell biology, physiology and medicine, we need to study model organisms. To cure human disease, we can learn from animals how they have evolved ways to protect themselves. To improve human performance, we can study the animal kingdom’s top performers and learn from their successes. Considering these important pointers, the authors review genetic engineering techniques that can translate our existing and future animal connections into benefits for human health and performance. Finally, they discuss the challenges associated with our animal connection: the history of pandemics caused by bacterial and viral pathogens demonstrates that there is a risk for transmission of diseases that can disrupt human societies. The recent COVID-19 outbreak is covered in detail as an example.
Author: Amit Agrawal
Publisher: BoD – Books on Demand
ISBN: 9535102656
Category : Medical
Languages : en
Pages : 538
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Book Description
The present two volume book "Brain Injury" is distinctive in its presentation and includes a wealth of updated information on many aspects in the field of brain injury. The Book is devoted to the pathogenesis of brain injury, concepts in cerebral blood flow and metabolism, investigative approaches and monitoring of brain injured, different protective mechanisms and recovery and management approach to these individuals, functional and endocrine aspects of brain injuries, approaches to rehabilitation of brain injured and preventive aspects of traumatic brain injuries. The collective contribution from experts in brain injury research area would be successfully conveyed to the readers and readers will find this book to be a valuable guide to further develop their understanding about brain injury.
Author: Franco Simini
Publisher: Springer
ISBN: 9812879285
Category : Technology & Engineering
Languages : en
Pages : 98
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Book Description
This volume presents the proceedings of CLABIO 2015 - II Latin American Conference on Bioimpedance, held in Montevideo, Uruguay - September 30 - October 02, 2015. The works cover a broad range in Biomedical Engineering and Computing, Medical Physics and Medical Sciences, Environment, Biology and Chemistry. The topics are: ·Bioimpedance Applications ·Bioimpedance Instrumentation ·Body and Tissue Composition ·Cell Culture and Cell Suspension ·Electrical Impedance Tomography ·Electrode Modelling ·Magnetic Induction - Electrical Impedance Tomography ·Magnetic Resonance - Electrical Impedance Tomography ·Nonlinear Phenomena ·Organ and Tissue Impedance ·Plant Tissue Impedance ·Skin Impedance Modelling ·Technological Advances in Bioimpedance ·Theory and Modelling
Author:
Publisher:
ISBN:
Category : American literature
Languages : en
Pages : 760
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Book Description
Author: Linda S. Costanzo
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781788717
Category : Medical
Languages : en
Pages : 364
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Book Description
This collection of 60 cases covers the clinically relevant physiology topics that first- and second-year medical students need to know for a first-year physiology course and for USMLE Step 1. Organized by body system, the book presents case studies with questions and problems, followed by complete explanations and solutions including diagrams, graphs, and charts. This edition includes four new cases and more illustrations and flowcharts. A companion Website will offer the fully searchable online text.
Author: Alessandro Silvani
Publisher: Frontiers Media SA
ISBN: 2889715809
Category : Science
Languages : en
Pages : 165
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Book Description
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309100674
Category : Science
Languages : en
Pages : 189
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Book Description
The patenting and licensing of human genetic material and proteins represents an extension of intellectual property (IP) rights to naturally occurring biological material and scientific information, much of it well upstream of drugs and other disease therapies. This report concludes that IP restrictions rarely impose significant burdens on biomedical research, but there are reasons to be apprehensive about their future impact on scientific advances in this area. The report recommends 13 actions that policy-makers, courts, universities, and health and patent officials should take to prevent the increasingly complex web of IP protections from getting in the way of potential breakthroughs in genomic and proteomic research. It endorses the National Institutes of Health guidelines for technology licensing, data sharing, and research material exchanges and says that oversight of compliance should be strengthened. It recommends enactment of a statutory exception from infringement liability for research on a patented invention and raising the bar somewhat to qualify for a patent on upstream research discoveries in biotechnology. With respect to genetic diagnostic tests to detect patient mutations associated with certain diseases, the report urges patent holders to allow others to perform the tests for purposes of verifying the results.
Author:
Publisher: Elsevier
ISBN: 0443193495
Category : Science
Languages : en
Pages : 522
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Book Description
Translational Bioinformatics is an emerging field in the direction of biomedical research. High throughput technologies can be applied to the generated biological data to develop the vaccine and personalized medicine. This volume consists of the chapters from different stalwart of the field covering the topics such as drug development, vector engineering, vaccine development and translational genomics. Chapters covered in this volume discuss the translational research related with cancer, Alzheimer disease and cardiovascular diseases. This volume includes the chapter describing the importance of computational resources and chemoinformatics for the translational health research. How Omics studies are helping to translate the laboratory data into the development of tools which are beneficial in the clinics have been described. How translational bioinformatics helpful in plant genomics to improve the crops have also been included in this volume. This volume has a chapter which describes the secrets of resistance development and further how these resistance are associated with human infectious diseases. This volume will be useful to the early career researcher in the development of research idea and develop their methodologies in the direction of bioinformatics and it will also give the insight to translate their findings. - Translational Bioinformatics - Health Informatics - Multi-omics
