Integrative Approaches to the Molecular Physiology of Inflammation

Integrative Approaches to the Molecular Physiology of Inflammation PDF Author: Enrique Hernández-Lemus
Publisher: Frontiers Media SA
ISBN: 2889458008
Category :
Languages : en
Pages : 334

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Book Description
"Integrative Approaches to the Molecular Physiology of Inflammation" presents contributions from the many different fields and approaches to the physiology and the molecular origins of inflammation; particularly those that may be involved in the development and evolution of diseased phenotypes. We selected among the wide scope and multiple views used to probe into the molecular origins of complex inflammatory phenotypes. This book consists of an Introductory Editorial and 6 thematic chapters encompassing 24 articles: 17 original research contributions and 7 review articles (5 reviews, 1 systematic review, and 1 minireview). Both, the research papers and the reviews provide varied and insightful approaches to different facets of inflammation with approaches ranging from general inflammation and signaling depictions deeply rooted on functional biology and physiology, to computational systems biology analyses, translational medicine, and pharmacological explorations. Model systems are also quite diverse: human subjects, mice and other mammal models, cell cultures and in silico, complex networks and database studies.

Integrative Approaches to the Molecular Physiology of Inflammation

Integrative Approaches to the Molecular Physiology of Inflammation PDF Author: Enrique Hernández-Lemus
Publisher: Frontiers Media SA
ISBN: 2889458008
Category :
Languages : en
Pages : 334

Get Book Here

Book Description
"Integrative Approaches to the Molecular Physiology of Inflammation" presents contributions from the many different fields and approaches to the physiology and the molecular origins of inflammation; particularly those that may be involved in the development and evolution of diseased phenotypes. We selected among the wide scope and multiple views used to probe into the molecular origins of complex inflammatory phenotypes. This book consists of an Introductory Editorial and 6 thematic chapters encompassing 24 articles: 17 original research contributions and 7 review articles (5 reviews, 1 systematic review, and 1 minireview). Both, the research papers and the reviews provide varied and insightful approaches to different facets of inflammation with approaches ranging from general inflammation and signaling depictions deeply rooted on functional biology and physiology, to computational systems biology analyses, translational medicine, and pharmacological explorations. Model systems are also quite diverse: human subjects, mice and other mammal models, cell cultures and in silico, complex networks and database studies.

Fibrosis and Inflammation in Tissue Pathophysiology

Fibrosis and Inflammation in Tissue Pathophysiology PDF Author: Elvira Forte
Publisher: Frontiers Media SA
ISBN: 2889744973
Category : Science
Languages : en
Pages : 369

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Book Description


Respiratory Regulation - The Molecular Approach

Respiratory Regulation - The Molecular Approach PDF Author: Mieczyslaw Pokorski
Publisher: Springer Science & Business Media
ISBN: 9400745494
Category : Medical
Languages : en
Pages : 353

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Book Description
This book, an international collaborative effort in the area of molecular respiratory research, showcases a broad range of multidisciplinary approaches to unravel and analyze the underlying mechanisms of a spectrum of respiratory ailments. It discusses immunological and genetic respiratory disorders, cancer, respiratory allergies and cough, sleep disordered breathing and many others. Exciting new results and up-to-date critical overviews of widely debated topics pertaining to respiratory disorders are presented. The contributions provide evidence for the growing interest of the international community of researchers in the field of respiration. The book incorporates modern molecular approaches to diagnostic and treatment solutions, underscoring the need for rational, evidence-based treatment methods. Combining cutting edge basic and clinical research with expert knowledge and experience this book is essential reading for medical students, research scientists and practicing specialists in pulmonology, immunology and allergology.

Inflammation

Inflammation PDF Author: Björn E. Clausen
Publisher: Humana
ISBN: 9781493967841
Category : Medical
Languages : en
Pages : 0

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Book Description
This volume presents a broad selection of cutting-edge methods and tools that will enable the reader to investigate the multi-faceted manifestations of inflammation. Inflammation: Methods and Protocols is divided into four sections: the first three sections describe protocols investigating immune-mediated inflammatory disease models affecting barrier organs to the environment; the skin, the lung, and the intestinal and oral mucosa. The fourth section illustrates inflammatory disease models of the brain, joints, and vasculature. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and practical, Inflammation: Methods and Protocols aims to inspire the experienced investigator and the young experimenter alike to disentangle the fascinating process of inflammation.

Essential Concepts in Molecular Pathology

Essential Concepts in Molecular Pathology PDF Author: William B. Coleman
Publisher: Academic Press
ISBN: 0128132582
Category : Medical
Languages : en
Pages : 634

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Book Description
Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology

Comprehensive Treatment of Chronic Pain by Medical, Interventional, and Integrative Approaches

Comprehensive Treatment of Chronic Pain by Medical, Interventional, and Integrative Approaches PDF Author: Timothy R Deer
Publisher: Springer Science & Business Media
ISBN: 1461415608
Category : Medical
Languages : en
Pages : 1084

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Book Description
Edited by master clinician-experts appointed by the American Academy of Pain Medicine, this is a state-of-the-art multidisciplinary textbook covering medical, interventional, and integrative approaches to the treatment and management of pain. It is designed as a practical and comprehensive primary reference for busy physicians and is also an up-to-date resource for preparing for certification examinations in pain medicine. · Written and edited by world-class authorities · “Key Points” preview contents of each chapter · Leading edge medical topics, such as monitoring opioid use and abuse, and the emerging role of cannabinoids in pain treatment · Expert guidance on full range of interventional techniques · Clinical anatomy and physiology for the interventionist · Behavioral dimensions of the experience and management of pain · Integrative approaches for treating the “whole person” · Legal issues, such as failure to treat pain · First-hand patient accounts

Complex Systems and Computational Biology Approaches to Acute Inflammation

Complex Systems and Computational Biology Approaches to Acute Inflammation PDF Author: Yoram Vodovotz
Publisher: Springer Nature
ISBN: 3030565106
Category : Medical
Languages : en
Pages : 307

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Book Description
This second edition expands upon and updates the vital research covered in its predecessor, by presenting state-of-the-art multidisciplinary and systems-oriented approaches to complex diseases arising from and driven by the acute inflammatory response. The chapters in this volume provide an introduction to different types of computational modeling, and how these methods can be applied to specific inflammatory diseases, with a focus on providing readers a roadmap for integrating advanced mathematical and computational techniques with traditional experimental methods. In this second edition, we cover both well-established and emerging modeling methods, especially state-of-the-art machine learning approaches and the integration of data-driven and mechanistic modeling. This volume introduces the concept of Model-based Precision Medicine as an alternative approach to the current view of Precision Medicine, based on leveraging mechanistic computational modeling to decrease cost while increasing the information value of the data being obtained. By presenting the role of computational modeling as an integrated component of the research process, Complex Systems and Computational Biology Approaches to Acute Inflammation: A Framework for Model-based Precision Medicine offers a window into the recent past, the present, and the future of computationally-augmented biomedical research.

Muscle Regeneration

Muscle Regeneration PDF Author: Alexander Mauro
Publisher: Raven Press (ID)
ISBN:
Category : Medical
Languages : en
Pages : 582

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Book Description


Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injury

Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injury PDF Author: Rajkumar Rajendram
Publisher: Academic Press
ISBN: 0128224282
Category : Medical
Languages : en
Pages : 558

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Book Description
Spinal injury affects about 10 million people annually worldwide, impacting on the family unit and causing lifelong disabilities, with varied symptoms including paresthesia, spasticity, loss of motor control, and often severe pain. Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injury will enhance readers’ understanding of the biological and psychological effects of spinal cord injury. Featuring chapters on gene expression, metabolic effects, and behavior, this volume discusses in detail the impact of spinal cord injury to better understand the underlying pathways and processes. The book has applicability for neuroscientists, neurologists, clinicians, and anyone working to better understand these injuries. Summarizes the neuroscience of spinal cord injury, including cellular and molecular biology Contains chapter abstracts, key facts, dictionary, and summary points to aid in understanding Features chapters on signaling and hormonal events Includes plasticity and gene expression Examines health and stress behaviors after spinal cord injury

Exercise Physiology

Exercise Physiology PDF Author: Philippe Connes
Publisher: IOS Press
ISBN: 1607504960
Category : Medical
Languages : en
Pages : 692

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Book Description
There is no doubt that if the field of exercise physiology is to make further advancements, the various specialized areas must work together in solving the unique and difficult problems of understanding how exercise is initiated, maintained and regulated at many functional levels, and what causes us to quit. Exercise is perhaps the most complex of physiological functions, requiring the coordinated, integrated activation of essentially every cell, tissue and organ in the body. Such activation is known to take place at all levels - from molecular to systemic. Focusing on important issues addressed at cellular and systemic levels, this handbook presents state-of-the-art research in the field of exercise physiology. Each chapter serves as a comprehensive resource that will stimulate and challenge discussion in advanced students, researchers, physiologists, medical doctors and practitioners. Authored by respected exercise physiologists from nineteen countries, each chapter has been significantly updated to provide up-to-date coverage of the topics and to offer complete descriptions of the many facets of the most physiological responses from a cellular to an integrative approach within individual body systems in normal and disease states and includes some chapters that are rarely addressed in exercise physiology books, such as the influence of exercise on endothelium, vasomomotor control mechanisms, coagulation, immune function and rheological properties of blood, and their influence on hemodynamics. This book represents the first iteration to provide such a work. Normal exercise responses divided into muscle function, bioenergetics, and respiratory, cardiac and blood/vascular function; Fitness, training, exercise testing and limits to exercise; Exercise responses in different environments; Beneficial effects of exercise rehabilitation on ageing and in the prevention and treatment of disease states; Rarely addressed issues such as the influence of exercise on endothelium, vasomotor control mechanisms, coagulation, immune function and rheological properties of blood and their influence on hemodynamics. IOS Press is an international science, technical and medical publisher of high-quality books for academics, scientists, and professionals in all fields. Some of the areas we publish in: -Biomedicine -Oncology -Artificial intelligence -Databases and information systems -Maritime engineering -Nanotechnology -Geoengineering -All aspects of physics -E-governance -E-commerce -The knowledge economy -Urban studies -Arms control -Understanding and responding to terrorism -Medical informatics -Computer Sciences