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Author: Barbara Hansen
Publisher: CRC Press
ISBN: 0203217411
Category : Medical
Languages : en
Pages : 386
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Book Description
Type II diabetes has developed into a global epidemic, with nearly 20 type II patients for every type I individual. Preceding the onset of type II diabetes is a prolonged episode of insulin resistance featuring a host of detrimental symptoms. This period comprises a disease referred to as Insulin Resistance Syndrome or Metabolic Syndrome. In
Author: Barbara Hansen
Publisher: CRC Press
ISBN: 0203217411
Category : Medical
Languages : en
Pages : 386
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Book Description
Type II diabetes has developed into a global epidemic, with nearly 20 type II patients for every type I individual. Preceding the onset of type II diabetes is a prolonged episode of insulin resistance featuring a host of detrimental symptoms. This period comprises a disease referred to as Insulin Resistance Syndrome or Metabolic Syndrome. In
Author: Andrew Krentz
Publisher: John Wiley & Sons
ISBN: 0470698381
Category : Medical
Languages : en
Pages : 202
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Book Description
Insulin resistance, defined as a reduced biological action of insulin, has emerged as a major factor in the development and progression of a number of common non-communicable diseases in man. The role of insulin resistance in the aetiology of type 2 diabetes is particularly well-established. However, insulin resistance has also come to be regarded as a key component of a broader syndrome of common metabolic defects that conspire to increase the risk of atherosclerotic coronary heart disease. The ramifications of insulin resistance now embrace many different medical specialties. The objective of this book is to summarize the current state of knowledge about insulin resistance. Section 1 (Pathophysiology of Insulin Resistance) considers the development of current concepts of insulin resistance. This is followed by a critical review of techniques for the assessment of insulin action in humans. The section concludes with an outline of current hypotheses concerning the molecular defects responsible for insulin resistance. Section 2 (Insulin Resistance in Clinical Medicine) broadens the discussion to include physiological and pathological conditions with which insulin resistance is associated; the effects of drug treatment on insulin sensitivity are also considered. Section 3 (Management of Insulin Resistance and Associated Conditions) focuses on the avoidance and treatment of insulin resistance in its clinical manifestations. A discussion of the potential benefits of non-pharmacological measures prefaces a review of the range of drugs used in the treatment of type 2 diabetes and related disorders. References are confined to key articles at the end of each section. Improved nutrition allied to increased levels of physical exercise are of crucial importance in the battle to stem the increasing incidence and prevalence of insulin resistance; however, translation of such advice into action has proved difficult in practice. Thus, other approaches have been explored. Recent years have witnessed considerable progress in the pharmacological management of insulin resistance. In particular, the thiazolidinediones (and other insulin-sensitizing drugs) appear to provide a more specific assault on insulin-resistance. Clinical experience with these agents remains relatively limited and serious hepatotoxicity has clouded the first agent in this class - troglitazone. With its introduction into the USA in 1995 and driven by the publication of the United Kingdom Prospective Diabetes Study, metformin has enjoyed a renaissance. This well-established agent is finding application for new clinical indications. In parallel, the development of anti-obesity drugs continues apace. The molecular and genetic mechanisms underlying some forms of insulin resistance are being revealed. Original intellectual concepts such as the fetal origins hypothesis are challenging traditional views about the aetiology of insulin resistance and its clinical sequelae. These exciting scientific advances notwithstanding, the evolving global epidemic of obesity and type 2 diabetes represents an enormous public health challenge. Now more than ever, research must focus on identifying solutions that are applicable on the level of entire populations. By definition, these must also be practical and cost-effective.
Author: David Moller
Publisher: John Wiley & Sons
ISBN: 9780471939771
Category : Health & Fitness
Languages : en
Pages : 446
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Book Description
The past two decades have seen explosive gains in our understanding of the physiology and basic mechanisms of insulin action and the critical importance of insulin resistance in the pathogenesis of clinical disorders such as non-insulin dependent diabetes mellitus, essential hypertension and atherosclerotic cardiovascular disease. Insulin Resistance offers the first comprehensive review of the field, with integrated chapters providing up to date coverage of the essential components of basic and clinical research that have contributed to current understanding of the topic. There are chapters on basic mechanisms of insulin action, in depth discussions of insulin resistance syndromes from epidemiological, clinical and biochemical viewpoints and a discussion of therapeutic approaches to insulin resistance. Insulin Resistance will be an invaluable resource for clinicians and scientists with an interest in the mechanisms of insulin action, the clinical sequelae of hyperinsulinemia and future therapies of insulin resistance.
Author: Gita Ganguly Mukherjee
Publisher: Elsevier Health Sciences
ISBN: 8131232212
Category : Medical
Languages : en
Pages : 147
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Book Description
The insulin resistance syndrome can be defined as insulin resistance, compensatory hyperinsulinemia, and their associated co-morbidities. Clinically, the term insulin resistance syndrome describes a constellation of abnormalities such as obesity, hypertension, dyslipidemia, type 2 diabetes/hyperglycemia, and coronary artery disease. Insulin is responsible for glucose uptake into the body cells and tissues. The response of the cells to insulin varies from individual to individual. In some individuals, the tissue response to insulin may be diminished. This means that even with adequate levels of insulin, the glucose uptake into the cells and tissues is not optimal. This results in a compensatory over-secretion of insulin from the pancreas. The persistence of high levels of insulin in the blood or hyperinsulinemia is thought to be responsible for some of the abnormalities associated with this condition. However, the exact causal association of the condition with these disorders and the pathophysiology of their evolution are unclear. The most common underlying mechanism proposed is increased free fatty acids from abdominal fat in individuals with central obesity. This leads to deranged insulin signaling, reduced muscular glucose uptake, increased triglyceride synthesis, and hepatic gluconeogenesis. A genetic basis of the disease as well as several other factors such as tumor necrosis factor-α, adiponectin, leptin, Interleukin-6, and some adipokines have also been implicated. Insulin resistance syndrome is of clinical significance because of its association with potentially debilitating conditions that contribute to long-term morbidity and even mortality of the individual. People with insulin resistance syndrome are at an increased risk of developing type 2 diabetes, hypertension, dyslipidemia, myocardial infarction, polycystic ovarian disease, and fatty liver. In this book, we have tried to collate the experiences of the pioneers of this field on the subject and provide the reader a comprehensive view on the topic along with practical management points, which we are sure will benefit the physicians in their clinical practice. The contributors have focused on the condition as is prevalent in our subcontinent and have tried to give an insight on the issues pertaining to the same with a topical flavor.
Author: Anil Gupta
Publisher: Elsevier
ISBN: 012820379X
Category : Medical
Languages : en
Pages : 321
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Book Description
Understanding Insulin and Insulin Resistance is written in a simple and clear language illustrated with diagrams that show the complex interplay of various factors in the initiation of insulin resistance. The design is systematic and meticulous, portraying topics in a flow from simple to complex. This resource is intended for a broad audience spanning across biochemistry, medicine, dentistry, academia, physicians, and research scholars. It extends the approach to biochemistry, physiology, metabolism of insulin along with the coverage of pathophysiology of insulin resistance, its effects on the body tissues, and its analysis on insulin resistance syndrome.
Author:
Publisher:
ISBN:
Category : Diabetes
Languages : en
Pages : 8
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Book Description
Author: Antony J. Haynes
Publisher: Conari Press
ISBN: 1609256816
Category : Health & Fitness
Languages : en
Pages : 258
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Book Description
Insulin resistance, commonly known as Syndrome X, affects a staggering 1 in 5 people. It is characterized by the over-production of insulin and is the underlying cause of many serious health problems, including heart disease, type II diabetes, obesity, high blood pressure, and deep vein thrombosis. The Insulin Resistance Factor offers a unique nutritional plan to reverse the effects of insulin resistance through diet, exercise, and nutritional supplements. Experienced nutritionist Antony J. Haynes shows how to: Determine your level of insulin resistanceUnderstand the key nutrients, antioxidants, and foods that can reverse insulin resistancePrepare simple and delicious meals that won’t leave you hungryLower your risk of heart disease and cancerImprove your memory and concentrationLower your cholesterol and high blood pressureSlow the aging process For anyone who struggles with weight, lethargy, high blood pressure, or high cholesterol The Insulin Resistance Factor offers a solution.
Author: Bernt Lindahl
Publisher:
ISBN: 9789171914965
Category :
Languages : en
Pages : 73
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Book Description
Author: Ronald A. Codario
Publisher: Springer Science & Business Media
ISBN: 159259932X
Category : Medical
Languages : en
Pages : 257
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Book Description
Type 2 Diabetes, Pre-Diabetes, and the Metabolic Syndrome: The Primary Care Guide to Diagnosis and Management is an important addition to the literature for primary care phy- cians. It covers concisely and with attention to clinical relevance the full spectrum of insulin resistance and diabetes. This book gives a practical, no-nonsense approach to understanding the basic pathophysiology of diabetes and the metabolic syndrome, an approach to treatment with oral agents and insulin, and an approach to risk factor management. By putting all this information in one readable text, Dr. Codario provides a service to us all, facilitating the understanding of a body of knowledge that cannot be obtained through any attempt to read portions of much larger textbooks in the field. This textbook will serve as a resource for medical students, residents in family medicine and internal medicine, and attending physicians who wish to update and improve their kno- edge in the field of diabetes and the newly emerging science of the metabolic syndrome. In addition, it allows attending physicians the opportunity to obtain Continuing Medical E- cation credits while performing self-directed learning. At the end of reading Type 2 Dia- tes, Pre-Diabetes, and the Metabolic Syndrome: The Primary Care Guide to Diagnosis and Management, the physician should feel comfortable and confident that they have acquired a solid understanding of the latest information in the field, and by so doing, should be better able to take excellent care of patients with diabetes and the metabolic syndrome.
Author: Marie Feldman
Publisher: Simon and Schuster
ISBN: 1507214219
Category : Health & Fitness
Languages : en
Pages : 272
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Book Description
Lose weight while enjoying delicious meals with these 125 insulin resistant recipes and meal plans to improve your health and lower your risk for type 2 diabetes. Many people struggle with their weight, trying every new diet and health trend but still are unable to keep the weight off or lose unwanted belly fat. The problem may not be lack of willpower, but insulin resistance. When insulin can’t do its job of removing sugar from the blood, that sugar is turned to fat, causing weight gain and increasing the risk of type 2 diabetes. But this damage can be reversed simply by changing your diet and activity level. In The Everything Guide to the Insulin Resistance Diet, you will learn how to choose healthy foods like fruits, vegetables, whole grains, fish, and lean poultry, while limiting the amount of unhealthy fat, sugar, meats, and processed starches. Now you can make the lifestyle changes you need to lose weight and improve your health with this valuable resource that includes 125 recipes and a 10-week plan for healthy eating and increased activity. With this guidebook you can have the body—and health—of your dreams, all while eating the delicious food you love!
