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Author: Christopher J. Barker
Publisher: Humana
ISBN:
Category : Science
Languages : en
Pages : 260
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Book Description
This text introduces the basic methodological tools to measure inositol lipids and phosphates and also describes new approaches that have become available in the last ten years, including g RNA-silencing and the protocols involving inositol pyrophosphates.
Author: Christopher J. Barker
Publisher: Humana
ISBN:
Category : Science
Languages : en
Pages : 260
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Book Description
This text introduces the basic methodological tools to measure inositol lipids and phosphates and also describes new approaches that have become available in the last ten years, including g RNA-silencing and the protocols involving inositol pyrophosphates.
Author: A. Kuksis
Publisher: Elsevier
ISBN: 0080930301
Category : Science
Languages : en
Pages : 1001
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Book Description
This book offers a wide ranging and review of cutting edge developments along with tried and tested methods for isolation, resolution and quantification of inositol phospholipids and inositol polyphosphates in both cells and tissues. It includes detailed and rigorous methodology for identification of molecular species of inositol phospholipids, including their phosphates and glycans, with numerous examples of specific applications. Wherever available, both chromatographic and mass spectrometric evidence is presented for specific phospholipid involvement in the biochemical transformations accompanying metabolic signalling events and, where possible, controversies have been resolved on basis of analytical ambiguity. The review of the lipid analyses extends to products of phosphatidylinositol kinases, phosphatases and lipases. A general review chapter is included on metabolic signalling with special emphasis on the lipid products of 3-kinases. In view of the general lack of commercially available standards for inositol phospholipids and inositol phosphates, the book concludes with a chapter on the preparation and collection of chromatographic and mass spectrometric proof of their purity and identity. This book complements recent books and reviews on the mechanisms metabolic signalling, receptor binding and the polypeptide structure of the proteins involved in the various signalling pathways. It also complements those texts that deal exclusively with the chemical synthesis of the phosphatidylinositols and their polyphosphates and glycans.
Author: R. H. Michell
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 568
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Book Description
The discovery that inositol lipids are integral in cellular signaling mechanisms has been one of the most exciting breakthroughs in recent years. As secondary messengers in a wide variety of tissues and involved processes as diverse as rapid contraction of skeletal muscle, insulin secretion, and the slow activation of cell proliferation in cancer cells, their impact on biochemistry is akin to that of cyclic AMP two decades ago. Drawing together the many strands of research on inositol lipid-mediated signalling and containing contributions by leading authorities in their fields, Inositol Lipids in Cell Signalling is essential for any involved biochemist, cell biologist, or pharmacologist.
Author: John N. Fain
Publisher: Academic Press
ISBN: 1483288323
Category : Science
Languages : en
Pages : 376
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Book Description
Many of the phospholipases and even the receptor for inositol 1,4,5-trisphosphate have recently been cloned and sequenced and play an important role in neurotransmission. Methods developed in recent years for the study of the enzymes and intermediates involved in the regulation of neuronal signal transduction involving phospholipid turnover are presented in this volume. - Techniques for examining the role of phosphoinositides in signal transduction - Techniques related to protein kinase C - Analysis of inositol phosphates - Techniques to analyze phospholipid turnover in the brain
Author: R. H. Michell
Publisher: Cold Spring Harbor Laboratory Press
ISBN:
Category : Nature
Languages : en
Pages : 184
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Book Description
Author: Michael J. O. Wakelam
Publisher: Portland Press
ISBN: 9781855781665
Category : Medical
Languages : en
Pages : 277
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Book Description
The Cell Biology of Inositol Lipids and Phosphates is the published proceedings of the Biochemical Society's Annual Symposium held at the University of Birmingham on 29-31 March 2006, which featured presentations from international experts from across the field of cell signalling who have contributed to this volume. contribution to the field.
Author: Jamie Alistair Stuart
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: B.B. Biswas
Publisher: Springer Science & Business Media
ISBN: 1461303435
Category : Science
Languages : en
Pages : 433
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Book Description
`The heterogeneity of topics ... is very ambitious, and the result is, overall, successful because of the high quality of the individual contributions ... highly recommended.' -American Scientist, from a review of a previous volume Volume 26 examines the emerging areas of signal transduction based on myoinositol phosphates and Ca2+ while focusing on plant and animal responses. Chapters explore synthesis, separation, and identification of different inositol phosphates.
Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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Book Description
Author: P. Michael Conn
Publisher:
ISBN:
Category : Calcium
Languages : en
Pages : 552
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Book Description
The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.
