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Author: Md Saquib Hasnain
Publisher: Academic Press
ISBN: 0323885780
Category : Science
Languages : en
Pages : 661
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Book Description
Inorganic Nanosystems: Theranostic Nanosystems, Volume Two examines the applications of nanotherapeutic systems and nanodiagnostics in relation to polymeric nanosystems. In the last decade, numerous biopolymers have been utilized to prepare polymeric nanosystems for therapeutic applications. These biopolymers include polylactic acid, polylactide-co-glycolide, polycaprolactone, acrylic polymers, cellulose and cellulose derivatives, alginates, chitosan, gellan gum, gelatin, albumin, chontroitin sulfate, hyaluronic acid, guar gum, gum Arabic, gum tragacanth, xanthan gum, and starches. Besides these biopolymers, grafted polymers are also being used as advanced polymeric materials to prepare many theranostic nanocarriers and nanoformulations. This book explores the array of polymeric nanosystems to understand therapeutic potentials. It will be useful to pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals, and regulatory scientists actively involved in the pharmaceutical product and process development of tailor-made polysaccharides in drug delivery applications. - Contains in-depth discussions of the inorganic nanosystems including high-quality graphics, flowcharts, and graphs for enhanced understanding - Reviews the literature on inorganic nanosystems while also suggesting new avenues - Includes contributions in all areas of inorganic nanosystems, providing a thorough and interdisciplinary work
Author: Md Saquib Hasnain
Publisher: Academic Press
ISBN: 0323885780
Category : Science
Languages : en
Pages : 661
Get Book Here
Book Description
Inorganic Nanosystems: Theranostic Nanosystems, Volume Two examines the applications of nanotherapeutic systems and nanodiagnostics in relation to polymeric nanosystems. In the last decade, numerous biopolymers have been utilized to prepare polymeric nanosystems for therapeutic applications. These biopolymers include polylactic acid, polylactide-co-glycolide, polycaprolactone, acrylic polymers, cellulose and cellulose derivatives, alginates, chitosan, gellan gum, gelatin, albumin, chontroitin sulfate, hyaluronic acid, guar gum, gum Arabic, gum tragacanth, xanthan gum, and starches. Besides these biopolymers, grafted polymers are also being used as advanced polymeric materials to prepare many theranostic nanocarriers and nanoformulations. This book explores the array of polymeric nanosystems to understand therapeutic potentials. It will be useful to pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals, and regulatory scientists actively involved in the pharmaceutical product and process development of tailor-made polysaccharides in drug delivery applications. - Contains in-depth discussions of the inorganic nanosystems including high-quality graphics, flowcharts, and graphs for enhanced understanding - Reviews the literature on inorganic nanosystems while also suggesting new avenues - Includes contributions in all areas of inorganic nanosystems, providing a thorough and interdisciplinary work
Author: Julia Pérez Prieto
Publisher: Elsevier
ISBN: 9780128145319
Category : Technology & Engineering
Languages : en
Pages : 0
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Book Description
Nanoparticles are usually designed for specific applications and selection of the most convenient capping can be a complex task, but is crucial for successful design. In this volume, the authors discuss the selection of functional cappings to coat nanoparticles in a range of different applications. The opening chapter provides an understanding of basic aspects of surface chemistry at the nanoscale. Each following chapter covers a particular kind of capping, beginning with a basic introduction and describing characteristics such as structure, functionality, solubility, (photo)physics, and toxicity. Special emphasis is placed on how important these specific features are in the preparation of smart nanomaterials. In-depth explanations and examples are then presented, highlighting the latest results and cutting-edge research carried out with the selected capping according to the kind of nanoparticle employed (such as rare-earth doped, semiconducting, and metallic). An additional chapter focusses on computational techniques for modelling nanosurfaces. Photoactive Inorganic Nanoparticles: Surface Composition and its Role in Nanosystem Functionality will be a valuable working resource for graduate students, researchers, and industry R&D professionals working in the field of applied nanomaterials.
Author: Alexandru Mihai Grumezescu
Publisher: William Andrew
ISBN: 0128136626
Category : Science
Languages : en
Pages : 727
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Book Description
Inorganic Frameworks as Smart Nanocarriers for Drug Delivery brings together recent research in the area of inorganic frameworks for drug delivery. Different types of nanocarriers are presented and discussed in detail, providing an up-to-date overview on inorganic nanoparticles with pharmaceutical applications. Written by a diverse range of international academics, this book is a valuable reference resource for researchers in biomaterials, the pharmaceutical industry, and those who want to learn more about the current applications of inorganic smart nanocarriers. - Includes assembly methods for a variety of smart nanocarrier systems, also showing how they are applied - Highlights how metal-oxide nanoparticles are effectively used in drug delivery - Assesses the pros and cons of different metallic nanomaterials as drug carriers
Author: Stefan T. Bromley
Publisher: CRC Press
ISBN: 9781466576414
Category : Science
Languages : en
Pages : 0
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Book Description
Offering a detailed summary of available modeling methods, both “top-down” and “bottom-up”, this book offers systematic coverage of the use of modeling in the development and application of inorganic nano-materials in industry including sensors, optics, biotechnology, and solar cells. It provides readers with the necessary information to choose the right models and methods for describing particular physical and chemical properties of inorganic materials at varying length scales. Sections include Structure and Dimensionality; Thermodynamics and Nucleation; Magnetic, Optical, and Electronic and Transport Properties; and Case Studies.
Author: Prashant Kesharwani
Publisher: Elsevier
ISBN: 044322045X
Category : Science
Languages : en
Pages : 896
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Book Description
Theranostics Nanomaterials in Drug Delivery presents the most recent advances in the development of theranostic nanomaterials for drug delivery. This book compiles reports and studies on the latest changes and improvements of theranostic nanocarriers such as nanoemulsions, liposomes, exosomes, polymeric micelles, PLGA nanoparticles, chitosan nanoparticles, dendrimer, quantum dots, silica nanoparticles, gold nanoparticles, silver nanoparticles, magnetic nanoparticles, and many more, all of which can help in the sensitive diagnosis, precise targeting, and efficient and controlled delivery of nanomaterials to control various diseases at different clinical stages. Theranostics nanomaterials in drug delivery will serve as a solid foundation and reference for pharmaceutical scientists, undergraduate and postgraduate students, researchers, and experts in the medical field involved in the development of advanced drug delivery systems. - Presents a compilation of thoroughly analyzed data and results regarding the usage of theranostics nanocarriers as a platform for diagnosis and treatment of various diseases - Gathers novel drug delivery applications of theranostics nanocarriers in biological milieu and discusses the principles behind the formation, characterization, applications, and future perspectives of theranostics for targeted therapy development - Discusses the most recent technologies in theranostics nanometrials to help readers define major gaps in knowledge that can lead new scientific breakthroughs and discoveries
Author: Ashutosh Kumar Shukla
Publisher: Elsevier
ISBN: 0081025807
Category : Technology & Engineering
Languages : en
Pages : 552
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Book Description
Green Synthesis, Characterization and Applications of Nanoparticles shows how eco-friendly nanoparticles are engineered and used. In particular, metal nanoparticles, metal oxide nanoparticles and other categories of nanoparticles are discussed. The book outlines a range of methodologies and explores the appropriate use of each. Characterization methods include spectroscopic, microscopic and diffraction methods, but magnetic resonance methods are also included as they can be used to understand the mechanism of nanoparticle synthesis using organisms. Applications covered include targeted drug delivery, water purification and hydrogen generation. This is an important research resource for those wishing to learn more about how eco-efficient nanoparticles can best be used. Theoretical details and mathematical derivations are kept to a necessary minimum to suit the need of interdisciplinary audiences and those who may be relatively new to the field. - Explores recent trends in growth, characterization, properties and applications of nanoparticles - Gives readers an understanding on how they are applied through the use of case studies and examples - Assesses the advantages and disadvantages of a variety of synthesis and characterization techniques for green nanoparticles in different situations
Author: Lara Scheherazade Milane
Publisher: CRC Press
ISBN: 1000505936
Category : Science
Languages : en
Pages : 511
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Book Description
We have surpassed the omics era and are truly in the Age of Molecular Therapeutics. The fast-paced development of SARS-CoV-2 vaccines, such as the mRNA vaccines encoding the viral spike protein, demonstrated the need for and capability of molecular therapy and nanotechnology-based solutions for drug delivery. In record speed, the SARS-CoV-2 viral RNA genome was sequenced and shared with the scientific community, allowing the rapid design of molecular therapeutics. The mRNA vaccines exploit the host cell endoplasmic reticulum to produce viral spike proteins for antigen presentation and recognition by the innate and adaptive immune system. Lipid nanoparticles enable the delivery of the fragile, degradation-sensitive nucleic acid payloads. Molecular-based therapeutics and nanotechnology solutions continue to drive the scientific and medical response to the COVID-19 pandemic as new mRNA, DNA, and protein-based vaccines are developed and approved and the emergency use approved vaccines are rapidly manufactured and distributed throughout the globe. The need for molecular therapies and drug delivery solutions is clear, and as these therapies progress and become more specialized there will be important advancements in organelle targeting. For example, using organelle targeting to direct lipid nanoparticles with mRNA payloads to the endoplasmic reticulum would increase the efficacy of mRNA vaccines, reducing the required dose and therefore the biomanufacturing demand. Likewise, improving the delivery of DNA therapeutics to the nucleus would improve efficacy. Organelles and molecules have always been drug targets, but until recently we have not had the tools or capability to design and develop such highly specific therapeutics. Organelle targeting has far-reaching implications. For example, mitochondria are central to both energy production and intrinsic apoptosis. Effectively targeting and manipulating mitochondria has therapeutic applications for diseases such as myopathies, cancer, neurodegeneration, progerias, diabetes, and the natural aging process. The SARS-CoV-2 vaccines that exploit the endoplasmic reticulum (for mRNA vaccines) and the nucleic translational process (DNA vaccines) attest to the need for organelle and molecular therapeutics. This book covers the status, demand, and future of organelle- and molecularly targeted therapeutics that are critical to the advancement of modern medicine. Organelle and molecular targeting is the drug design and drug delivery approach of today and the future; understanding this approach is essential for students, scientists, and clinicians contributing to modern medicine.
Author: Chandra P. Sharma
Publisher: Elsevier
ISBN: 0323509231
Category : Technology & Engineering
Languages : en
Pages : 454
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Book Description
Drug Delivery Nanosystems for Biomedical Application reviews some of the most challenging nanosystems with different routes of delivery that are useful for specific drugs, from both efficacy and bioavailability points-of-view. The chapters explore how this area is developing, the present state of the field, and future developments, in particular, inorganic, metallic, polymeric, composite and lipid nanosystems and their possible evolution to clinical applications. The book is a valuable research reference for both researchers and industrial partners who are not only interested in learning about this area, but also want to gain insights on how to move towards translational research. - Focuses on applications, including tissue engineering and regenerative technologies, showing how nanosystems are used in practice - Explores how nanosystems are used to deliver a variety of drugs, including peptides, hormone growth factors and genes - Assesses the safety and nanotoxicity aspects of drug delivery nanosystems
Author: Kabali Vijai Anand
Publisher: Elsevier
ISBN: 0323914004
Category : Technology & Engineering
Languages : en
Pages : 480
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Book Description
Antimicrobial Nanosystems: Fabrication and Development provides an in-depth review of nanotechnological advancements in the fields of biotechnology and pharmaceutical industries to counteract bacterial infections and related health issues. Functionalized nanomaterials and their processes are covered, along with the theory and fabrication of antimicrobial nanosystems. The potential applications of antimicrobial nanosystems are also discussed along with their challenges and commercialization. This book discusses the most frequent problems caused by resistant microorganisms and difficult-to-treat bacteria and highlights the impact of recently developed antimicrobial nanosystems. Various methodsto obtain efficient nanomaterials with antimicrobial properties are described, along with their advantages, challenges, and main applications. The design of targeting antimicrobial therapeutics, able to specifically detect pathogenic microorganisms and to act in a very specific manner, is thoroughly investigated. - Discusses the most frequent problems caused by resistant microorganisms and difficult-to-treat bacteria - Includes various methods to obtain efficient nanomaterials with antimicrobial properties that are described along with their advantages, challenges and main applications - Covers the ability of microbes to adapt and select resistance, a major challenge in the design of alternative antimicrobial agents - Provides various sections that illustrate the fabrication and development of antimicrobial nanosystems
Author: Jean Cornier
Publisher: John Wiley & Sons
ISBN: 3527340548
Category : Technology & Engineering
Languages : en
Pages : 804
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Book Description
Dieses Fachbuch legt den Schwerpunkt auf konkrete Methoden und die jüngsten Fortschritte bei der Anwendung von Nanotechnologie für die Entwicklung neuer medikamentöser Therapieansätze und die medizinische Diagnostik. Von den Grundlagen der Nanopharmazie, einschließlich Charakterisierung und Herstellungsverfahren, bis hin zur Rolle von Nanopartikeln und Wirkstoffen wird das Fachgebiet umfassend dargestellt. Anwendungsbeispiele beziehen sich auf Fragestellungen bei der Medikamentenentwicklung und die Übertragung auf die klinische Praxis, Marktchancen und Aspekte der industriellen Vermarktung. Die beschriebenen Anwendungen stammen aus der Behandlung von Krebserkrankungen und weiteren wichtigen Therapiebereichen wie Infektionskrankheiten und Dermatologie. Abgerundet wird das Fachbuch durch eine ausführliche Erörterung sicherheitsrelevanter, rechtlicher und gesellschaftlicher Fragen. Geschrieben von einem erstklassigen Team von Herausgebern und Autoren, die zu den führenden Experten in Europa und den USA sowie zu den Pionieren der Nanopharmazie gehören.
