Innovative theranostic approaches towards neuro-immunology in gliomas

Innovative theranostic approaches towards neuro-immunology in gliomas PDF Author: Lijie Zhai
Publisher: Frontiers Media SA
ISBN: 2832518354
Category : Medical
Languages : en
Pages : 225

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Innovative theranostic approaches towards neuro-immunology in gliomas

Innovative theranostic approaches towards neuro-immunology in gliomas PDF Author: Lijie Zhai
Publisher: Frontiers Media SA
ISBN: 2832518354
Category : Medical
Languages : en
Pages : 225

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Book Description


Central Nervous System Tumours

Central Nervous System Tumours PDF Author: Thomas James Deeley
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 346

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Inflammation in the CNS: Advancing the Field Using Intravital Imaging

Inflammation in the CNS: Advancing the Field Using Intravital Imaging PDF Author: Saparna Pai
Publisher: Frontiers Media SA
ISBN: 2889453642
Category :
Languages : en
Pages : 110

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Book Description
Inflammation of the CNS can have devastating, long-lived, and in some cases fatal consequences for patients. The stimuli that can induce CNS inflammation are diverse, and include infectious agents, autoimmune responses against CNS-expressed antigens, and sterile inflammation following ischemia or traumatic injury. In these conditions, cells of the immune system play central roles in promulgation and resolution of the inflammatory response. However, the immunological mechanisms at work in these diverse responses differ according to the nature of the response. Our understanding of the actions of immune cells in the CNS has been restricted by the difficulty in visualising leukocytes as they undergo recruitment from the cerebral microvasculature and following their entry into the CNS parenchyma. However, advances in in vivo microscopy over the last 10-15 years have overcome many of these difficulties, and studies using these forms of microscopy have revealed a wealth of new information regarding the cellular and molecular mechanisms of CNS inflammation. This Research Topic brings together state of the art reviews examining the use of in vivo imaging in investigating inflammation and leukocyte behaviour in the CNS. Papers in this Research Topic describe how in vivo microscopy has increased our understanding of the actions of immune cells in the inflamed CNS, following various stimuli including autoimmunity, infection and sterile inflammation.

Cancer Therapeutics And Imaging: Molecular And Cellular Engineering And Nanobiomedicine

Cancer Therapeutics And Imaging: Molecular And Cellular Engineering And Nanobiomedicine PDF Author: Kaushal Rege
Publisher: World Scientific
ISBN: 9813222565
Category : Science
Languages : en
Pages : 358

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Book Description
This book describes the latest advancements in molecular and cellular engineering approaches in addition to nanotechnology for cancer therapeutics and imaging. It also provides an excellent background and state-of-the-art developments in the fields of drug and gene delivery, engineering nanoparticles for therapy and diagnostics, and cancer imaging techniques.The contents of this book include chapters on cutting-edge science in molecular and cellular engineering and nanotechnology as applied to therapeutics and imaging in cancer diseases. The chapters also provide a comprehensive overview on gene therapy and delivery methods for cancer treatment, oral drug delivery and barriers, cancer imaging for diagnostics and therapy, and the latest developments in these fields.

Translational Nanomedicine

Translational Nanomedicine PDF Author: Robert A. Meyers
Publisher: Wiley-Blackwell
ISBN: 9783527337897
Category : Science
Languages : de
Pages : 0

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Book Description
The largest high-level encyclopedia on molecular medicine is now publishing a topical volume on Nanomedicine. The long awaited volume gives a comprehensive overview on nanomaterials in drug delivery, imaging and as therapeutics.

Cell Surface Proteases

Cell Surface Proteases PDF Author:
Publisher: Elsevier
ISBN: 0080490883
Category : Science
Languages : en
Pages : 475

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Book Description
Cell Surface Proteases provides a comprehensive overview of these important enzymes that catalyze the hydrolysis of a protein as it degrades to a simpler substance. In the 1990s, an explosion of new discoveries shed light on the role of cell surface proteases and extended it beyond degradation of extracellular matrix components to include its influence on growth factors, cell signaling, and other cellular events. This volume unites the scientific literature from across disciplines and teases out unified themes of interactions between cell surface proteases and interconnecting cell surface-related systems -- including integrins and other adhesion molecules. Scientists and students involved in developmental biology, cell biology and disease processes will find this an indispensable resource. * Provides an overview of the entire field of cell surface proteases in a single volume* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine * A thematic volume in the longest-running forum for contemporary issues in developmental biology with over 30 years of coverage

Translocator Protein (TSPO)

Translocator Protein (TSPO) PDF Author: Giovanni Natile
Publisher: MDPI
ISBN: 3038427578
Category : Science
Languages : en
Pages : 177

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Book Description
This book is a printed edition of the Special Issue "Translocator Protein (TSPO)" that was published in IJMS

Polymeric Biomaterials: Structure and function

Polymeric Biomaterials: Structure and function PDF Author: Severian Dumitriu
Publisher: CRC Press
ISBN: 142009470X
Category : Medical
Languages : en
Pages : 922

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Book Description
The third edition of a bestseller, this comprehensive reference presents the latest polymer developments and most up-to-date applications of polymeric biomaterials in medicine. Expanded into two volumes, the first volume covers the structure and properties of synthetic and natural polymers as well as bioresorbable hybrid membranes, drug delivery systems, cell bioassay systems, and electrospinning for regenerative medicine. This substantially larger resource includes state-of-the-art research and successful breakthroughs in applications that have occurred in the last ten years.

Targeted Drug Delivery : Concepts and Design

Targeted Drug Delivery : Concepts and Design PDF Author: Padma V. Devarajan
Publisher: Springer
ISBN: 3319113550
Category : Medical
Languages : en
Pages : 788

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Book Description
This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active targeting strategies, and various advanced drug delivery tools such as functionalized lipidic, polymeric and inorganic nanocarriers. Together, the twenty-three chapters cover a wide range of topics in the field, including tumor and hepatic targeting, polymer-drug conjugates, nanoemulsion, physical and biophysical characteristics of nanoparticles, and in vivo imaging techniques, among others. The book also examines advanced characterization techniques, regulatory hurdles and toxicity-related issues that are key features for successful commercialization of targeted drug delivery system products. Targeted Drug Delivery is a comprehensive reference guide for drug delivery researchers, both beginners and those already working in the field.

Drug Transport Across the Blood-brain Barrier

Drug Transport Across the Blood-brain Barrier PDF Author: A.G. de Boer
Publisher: CRC Press
ISBN: 9789057020322
Category : Medical
Languages : en
Pages : 240

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Book Description
The availability of various in vitro and in vivo techniques has considerably advanced the research on drug transport and metabolism across the blood-brain barrier (BBB). These specialized and sophisticated experimental strategies are of fundamental importance if one is to gain a greater understanding of enhanced and selective drug delivery to the brain. The reader will find in this book methods for in vitro endothelial/astrocyte cell culture models, and for in vivo intracerebral microdialysis to study drug tranport across the BBB. This book, however, is not merely a laboratory manual consisting of recipes for BBB research; it permits the presentation of the different methods in fine detail, revealing tricks and short cuts that frequently do not appear in the literature. The researcher is well aware that differences (subtle or otherwise) in experimental steps used in different laboratories may influence the outcome of any particular procedure. The book also illustrates the accessibility and the application of the different methods in different species. Background information of the protocol is given in every chapter, which also contains a literature list that the reader may wish to refer to for further information. This volume will be invaluable to basic researchers as well as to those involved in the search for agents suitable for pharmaceutic intervention in the central nervous system.