Infectious Process and Sepsis

Infectious Process and Sepsis PDF Author: Vincenzo Neri
Publisher:
ISBN: 9781838803940
Category :
Languages : en
Pages : 102

Get Book Here

Book Description
Sepsis is a very complex clinical condition that can be considered the central point of the infectious process: the arrival point in the evolution of a localized septic outbreak that has caused a systemic inflammatory reaction. In the clinical setting two important questions regarding the transition from local inflammation, with beneficial effect, to systemic inflammatory disease, with deleterious results, remain unanswered. First, why does the transition from local to systemic disease only occur in some subjects? Second, how long does this transition take? This book attempts to answer these questions. Chapters cover such topics as surgical infections, microbiota therapy in sepsis, cytokines for host immune response, and the role of serum amyloid A in the acute phase of sepsis.

Infectious Process and Sepsis

Infectious Process and Sepsis PDF Author: Vincenzo Neri
Publisher:
ISBN: 9781838803940
Category :
Languages : en
Pages : 102

Get Book Here

Book Description
Sepsis is a very complex clinical condition that can be considered the central point of the infectious process: the arrival point in the evolution of a localized septic outbreak that has caused a systemic inflammatory reaction. In the clinical setting two important questions regarding the transition from local inflammation, with beneficial effect, to systemic inflammatory disease, with deleterious results, remain unanswered. First, why does the transition from local to systemic disease only occur in some subjects? Second, how long does this transition take? This book attempts to answer these questions. Chapters cover such topics as surgical infections, microbiota therapy in sepsis, cytokines for host immune response, and the role of serum amyloid A in the acute phase of sepsis.

Infections and Sepsis Development

Infections and Sepsis Development PDF Author: Vincenzo Neri
Publisher:
ISBN: 9781839694585
Category : Septicemia
Languages : en
Pages : 0

Get Book Here

Book Description
Infection is a common clinical condition that may cause local inflammation but, in some cases, can lead to systemic inflammation, with sepsis and organ dysfunction. Septic shock is a condition of inadequate tissue perfusion and cellular use of oxygen due to the cytotoxic action of bacterial toxins. There is no relationship between the pathological characteristics and the severity of the primary septic outbreak and the development of septic shock, and the time that elapses until the start of the shock is not predictable. Thus, knowledge of the pathophysiology of septic shock is fundamental for treatment. This book presents a comprehensive overview of infectious agents and their therapeutic control, pathological conditions with infective etiology such as diabetic foot osteomyelitis and infections in neurosurgery, and the pathophysiology, diagnosis, and management of sepsis.

Core Concepts in Clinical Infectious Diseases (CCCID)

Core Concepts in Clinical Infectious Diseases (CCCID) PDF Author: Carlos Franco-Paredes
Publisher: Academic Press
ISBN: 0128044802
Category : Medical
Languages : en
Pages : 246

Get Book Here

Book Description
Core Concepts in Clinical Infectious Diseases (CCCID) provides medical students and researchers, infectious disease fellows, and practicing clinicians with key clinical concepts in the differential diagnosis and workup of infectious diseases. With the use of tables, charts, and problem-oriented medical diagnosis, it will provide a way of organizing and thinking about commonly seen clinical presentations of infectious diseases. Instead of discussing each disease process or any particular infectious process, this book will assist clinicians in seeing the forest and not focusing on the leaf. Graphs and tables have been constructed over 14 years of taking notes, teaching clinical infectious diseases, and discussing real clinical cases. This book is not about acquiring the structure of infectious diseases that is presented in classic textbooks of infectious disease; instead, it is about refining the process of putting the pieces together in clinical thinking to achieve an accurate clinical diagnosis and thus improved patient care. - Assists the reader in connecting the dots (process of accumulating real-time knowledge) during the thinking process of clinical decision-making in the area of infectious diseases - Uses tables and charts for easy understanding and application - Contains a manual style that targets different audiences, such as medical students, hospital medicine specialists, outpatient internal medicine practitioners, infectious disease fellows in training, and practicing clinicians - Provides an up-to-date discussion of core concepts in clinical infectious diseases

Handbook of Sepsis

Handbook of Sepsis PDF Author: W. Joost Wiersinga
Publisher: Springer
ISBN: 3319735063
Category : Medical
Languages : en
Pages : 264

Get Book Here

Book Description
This practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as fluid resuscitation, vasopressor therapy, response to multiorgan failure, antimicrobial therapy, and adjunctive immunotherapy. The closing section looks forward to the coming decade, discussing novel trial designs, sepsis in low- and middle-income countries, and emerging management approaches. The book is internatio nal in scope, with contributions from leading experts worldwide. It will be of value to residents and professionals/practitioners in the fields of infectious diseases and internal medicine, as well as to GPs and medical students.

Clinical Management of Shock

Clinical Management of Shock PDF Author: Stanislaw P. Stawicki
Publisher: BoD – Books on Demand
ISBN: 1838811702
Category : Medical
Languages : en
Pages : 210

Get Book Here

Book Description
Shock is a physiological state of war! From a healthcare provider perspective, the word “shock” is associated with a mixed array of feelings, including dread, well-founded fear, and deep respect. The physiological state of shock is well recognized for the associated destructive consequences, and its successful management requires prompt identification, immediate action, and sustained effort by all members of the healthcare team. This mindset of advanced preparation and constant readiness constitutes the foundation of the modern approach toward shock – early detection and prompt treatment for optimal outcomes. Despite the heterogeneity of “shock” as a clinico-pathological entity, there are some common threads that permeate all forms and manifestations of shock, with apparent increase in observed commonalities in the more advanced (and often irreversible) stages of the systemic syndrome. When faced with shock, the body and its systems do their best to compensate for the maldistribution of oxygen and nutrients. This is known as the so-called compensated shock. Beyond that, the body loses its ability to adjust any further, thus descending into “uncompensated shock,” with a refractory state characterized by vasoplegia and irreversible cardiovascular failure. As the reader journeys through the chapters of the book, he or she will read about various biomarkers and endpoints of resuscitation, explore different types of shock (e.g., septic, hemorrhagic, anaphylactic) and learn about some of the less often discussed topics such as neurogenic and spinal shock, as well as the amniotic fluid embolism. Our goals were to keep things clinically relevant and practically oriented, thus enabling the reader to apply the newly acquired knowledge in their everyday clinical routines. As the reader progresses through the book, we hope to help stimulate further discourse and innovative thinking about the topic. In this context, it is critical that basic, translational, and clinical research on shock continues to advance. Only through ongoing scientific progress can we help improve outcomes for patients with both rare and common forms of shock.

Review of Medical Microbiology and Immunology 15E

Review of Medical Microbiology and Immunology 15E PDF Author: Warren E. Levinson
Publisher: McGraw-Hill Education / Medical
ISBN: 9781259644498
Category : Medical
Languages : en
Pages : 832

Get Book Here

Book Description
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The most concise, clinically relevant, and current review of medical microbiology and immunology Review of Medical Microbiology and Immunology is a succinct, high-yield review of the medically important aspects of microbiology and immunology. It covers both the basic and clinical aspects of bacteriology, virology, mycology, parasitology, and immunology and also discusses important infectious diseases using an organ system approach. The book emphasizes the real-world clinical application of microbiology and immunology to infectious diseases and offers a unique mix of narrative text, color images, tables and figures, Q&A, and clinical vignettes. • Content is valuable to any study objective or learning style • Essential for USMLE review and medical microbiology coursework • 650 USMLE-style practice questions test your knowledge and understanding • 50 clinical cases illustrate the importance of basic science information in clinical diagnosis • A complete USMLE-style practice exam consisting of 80 questions helps you prepare for the exam • Pearls impart important basic science information helpful in answering questions on the USMLE • Concise summaries of medically important organisms • Self-assessment questions with answers appear at the end of each chapter • Color images depict clinically important findings, such as infectious disease lesions • Gram stains of bacteria, electron micrographs of viruses, and microscopic images depict fungi, protozoa, and worms • Chapters on infectious diseases from an organ system perspective

Sepsis Management in Resource-limited Settings

Sepsis Management in Resource-limited Settings PDF Author: Arjen M. Dondorp
Publisher: Springer
ISBN: 3030031438
Category : Medical
Languages : en
Pages : 226

Get Book Here

Book Description
This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.

McGraw-Hill's NAPLEX Review Guide

McGraw-Hill's NAPLEX Review Guide PDF Author: S. Scott Sutton
Publisher: McGraw Hill Professional
ISBN: 0071811540
Category : Medical
Languages : en
Pages : 1025

Get Book Here

Book Description
Everything you need to pass the NAPLEX® – comprehensive study material and two practice exams – in one student-reviewed package Written by an instructor who has taught thousand of students, this all-in-one study guide was developed and reviewed by pharmacists, faculty, students, and recent graduates – so you know it contains only the most relevant, up-to-date conent. You’ll find valuable foundational material and chapter-ending case application questions that cover every key topic included on the NAPLEX. Two downloadable practice tests with a total of 370 questions allowing you to pinpoint your weaknesses. Includes: Coverage that is organized around the NABP competencies and designed to sharpen problem-solving skills, put must-know information at your fingertips, and improve exam-taking ability More than 1400 case application questions, each with a detailed explanation of both correct and incorrect answer choices Takeaway Points at the end of every chapter that summarize key concepts Two complete downloadable practice tests, each with 185 questions

Vaccinology

Vaccinology PDF Author: Gregg N. Milligan
Publisher: John Wiley & Sons
ISBN: 0470656166
Category : Medical
Languages : en
Pages : 404

Get Book Here

Book Description
Vaccinology: An Essential Guide outlines in a clear, practical format the entire vaccine development process, from conceptualization and basic immunological principles through to clinical testing and licensing of vaccines. With an outstanding introduction to the history and practice of vaccinology, it also guides the reader through the basic science relating to host immune responses to pathogens. Covering the safety, regulatory, ethical, and economic and geographical issues that drive vaccine development and trials, it also presents vaccine delivery strategies, novel vaccine platforms (including experimental vaccines and pathogens), antigen development and selection, vaccine modelling, and the development of vaccines against emerging pathogens and agents of bioterror. There are also sections devoted to veterinary vaccines and associated regulatory processes. Vaccinology: An Essential Guide is a perfect tool for designed for undergraduate and graduate microbiologists and immunologists, as well as residents, fellows and trainees of infectious disease and vaccinology. It is also suitable for all those involved in designing and conducting clinical vaccine trials, and is the ideal companion to the larger reference book Vaccinology: Principles and Practice.

Hemodynamic Monitoring

Hemodynamic Monitoring PDF Author: Michael R. Pinsky
Publisher: Springer
ISBN: 3319692690
Category : Medical
Languages : en
Pages : 476

Get Book Here

Book Description
This book, part of the European Society of Intensive Care Medicine textbook series, teaches readers how to use hemodynamic monitoring, an essential skill for today’s intensivists. It offers a valuable guide for beginners, as well as for experienced intensivists who want to hone their skills, helping both groups detect an inadequacy of perfusion and make the right choices to achieve the main goal of hemodynamic monitoring in the critically ill, i.e., to correctly assess the cardiovascular system and its response to tissue oxygen demands. The book is divided into distinguished sections: from physiology to pathophysiology; clinical assessment and measurements; and clinical practice achievements including techniques, the basic goals in clinical practice as well as the more appropriate hemodynamic therapy to be applied in different conditions. All chapters use a learning-oriented style, with practical examples, key points and take home messages, helping readers quickly absorb the content and, at the same time, apply what they have learned in the clinical setting. The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care.