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Author: Ugo Ripamonti
Publisher: CRC Press
ISBN: 1040187978
Category : Medical
Languages : en
Pages : 152
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Book Description
The effects of the bone morphogenetic proteins (BMPs) family on bone formation are well documented, but the transforming growth factor (TGF)-beta ( isoforms are much less studied. The product of 20 years of study, Induction of Bone Formation in Primates: The Transforming Growth Factor- sums up editor Ugo Ripamonti's research into the osteogenic a
Author: Ugo Ripamonti
Publisher: CRC Press
ISBN: 1040187978
Category : Medical
Languages : en
Pages : 152
Get Book Here
Book Description
The effects of the bone morphogenetic proteins (BMPs) family on bone formation are well documented, but the transforming growth factor (TGF)-beta ( isoforms are much less studied. The product of 20 years of study, Induction of Bone Formation in Primates: The Transforming Growth Factor- sums up editor Ugo Ripamonti's research into the osteogenic a
Author: Ugo Ripamonti
Publisher: CRC Press
ISBN: 0429515308
Category : Medical
Languages : en
Pages : 218
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Book Description
The Geometric Induction of Bone Formation describes new biomimetic biomaterials that offer mechanistic osteogenic surfaces for the autonomous and spontaneous induction of bone formation without the addition of osteogenic soluble molecular signals of the transforming growth factor-β supergene family. The chapters frame our understanding of regenerative medicine in primate species, including humans. The goal is to unravel the fundamental biological mechanisms of bone formation unique to non-human and human primates. The broad target audience dovetails with several disciplines both in the academic and private biotech sectors primarily involved in molecular biology, tissue biology, tissue engineering, biomaterial science, and reconstructive, orthopedic, plastic, and dental surgery. Key Features Includes outstanding images of undecalcified whole mounted sections Summarizes non-human primate research – ideal for clinical translation Reviews methods for creating devices capable of making bone autonomously, i.e. an intrinsically osteo-inductive bioreactor and/or biomaterial Describes the spontaneous induction of bone formation including a whole spectrum of tissue biology, from basic molecular biology to clear-cut morphology and pre-clinical application in non-human primate species Intended for audiences in both academic research and the biotech industry
Author: Ugo Ripamonti
Publisher: CRC Press
ISBN: 1482216175
Category : Medical
Languages : en
Pages : 210
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Book Description
The effects of the bone morphogenetic proteins (BMPs) family on bone formation are well documented, but the transforming growth factor (TGF)-beta ( isoforms are much less studied. The product of 20 years of study, Induction of Bone Formation in Primates: The Transforming Growth Factor- sums up editor Ugo Ripamonti's research into the osteogenic a
Author: Christian R. Abee
Publisher: Academic Press
ISBN: 0123978386
Category : Medical
Languages : en
Pages : 867
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Book Description
The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The Diseases volume provides thorough reviews of naturally occurring diseases of nonhuman primates, with a section on biomedical models reviewing contemporary nonhuman primate models of human diseases. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. - Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in bioledical research - Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information - Includes four color images throughout
Author: T. Sam Lindholm
Publisher: World Scientific
ISBN: 9812706577
Category : Medical
Languages : en
Pages : 479
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Book Description
The bone morphogenetic protein (BMP) is a special growth factor for the induction of new bone formation. Today, the extract of the BMP originating from bone tissue as well as genetically modified BMPs, particularly BMP-2 and -7, can be used.Though the BMP as an implant is as yet an unregistered drug or medical tool in Europe and the US, specialists are confident that it will obtain final government approval based on the results of clinical tests conducted on more than 3000 patients.This important book focuses mainly on the clinical BMP treatment of patients OCo namely in orthopaedic cases (fractures, bone transplants, non-unions and pseudoarthroses), maxillofacial surgery (sinus lift before dental implantation), dental surgery (filling out of cavities) and spinal surgery (using a BMP implant instead of the patient's own bone)."
Author: Christian R. Abee
Publisher: Academic Press
ISBN: 0124159729
Category : Science
Languages : en
Pages : 3435
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Book Description
The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The publication emphasizes the biology and management, diseases, and biomedical models for nonhuman primate species most commonly used in research. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. The Biology and Management volume provides basic information on the natural biology of nonhuman primates and the current state of knowledge regarding captive management. The Diseases volume provides thorough reviews of naturally occurring diseases of nonhuman primates, with a section on biomedical models reviewing contemporary nonhuman primate models of human diseases. - Now in four color throughout, making the book more visually stimulating to enhance learning and ease of use - Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in biomedical research - Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information
Author:
Publisher: ScholarlyEditions
ISBN: 1464935211
Category : Science
Languages : en
Pages : 69
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Book Description
Advances in Transforming Growth Factor beta Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Transforming Growth Factor beta in a concise format. The editors have built Advances in Transforming Growth Factor beta Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Transforming Growth Factor beta in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Transforming Growth Factor beta Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author: Oliver Kayser
Publisher: John Wiley & Sons
ISBN: 3527605525
Category : Science
Languages : en
Pages : 336
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Book Description
With its focus on industrial pharmaceutical research, written by international experts from the industry, this book fills in a gap in the existing literature. It reflects the combination of such pharmaceutical interests as drug delivery, drug targeting, quality and safety management, drug approval and regulation, patenting issues and biotechnology fundamentals. Thus it provides practitioners in pharmaceutical biotechnology with all the relevant information from the shelf. The first part offers a comprehensive survey and review of the rapidly increasing array of biopharmaceuticals derived from the molecular biological approaches now widely available. This is followed by an extra section devoted to the very critical patenting and drug regulation issues. The whole is rounded off by detailed monographs of biotechnologically developed drugs that are already on the market. With a foreword of by Robert Langer, Kenneth J Germeshausen Professor of Chemical and Biomedical Engineering at the Massachusetts Institute of Technology. In 2002, he received the Charles Stark Draper Prize, the highest recognition for an engineer. Professor Langer is member of all three national academies - the Institute of Medicine, the National Academy of Engineering, and the National Academy of Sciences: "The book attempts to provide a balanced view of the biotechnological industry and the number of experts from industry sharing their knowledge and experience with the audience gives the book an outstanding value. All contributors provide with each chapter an up-to-date review on key topics in pharmaceutical biotechnology. This work is not only a valuable tool for the industrial expert but also for all pharmacists and scientists from related areas who wish to work with biotech drugs."
Author: Brian K. Hall
Publisher: Academic Press
ISBN: 0124166857
Category : Science
Languages : en
Pages : 911
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Book Description
Bones and Cartilage provides the most in-depth review and synthesis assembled on the topic, across all vertebrates. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage develop in embryos and are maintained in adults, how bone is repaired when we break a leg, or regenerates when a newt grows a new limb, or a lizard a new tail. The second edition of Bones and Cartilage includes the most recent knowledge of molecular, cellular, developmental and evolutionary processes, which are integrated to outline a unified discipline of developmental and evolutionary skeletal biology. Additionally, coverage includes how the molecular and cellular aspects of bones and cartilage differ in different skeletal systems and across species, along with the latest studies and hypotheses of relationships between skeletal cells and the most recent information on coupling between osteocytes and osteoclasts All chapters have been revised and updated to include the latest research. - Offers complete coverage of every aspect of bone and cartilage, with updated references and extensive illustrations - Integrates development and evolution of the skeleton, as well a synthesis of differentiation, growth and patterning - Treats all levels from molecular to clinical, embryos to evolution, and covers all vertebrates as well as invertebrate cartilages - Includes new chapters on evolutionary skeletal biology that highlight normal variation and variability, and variation outside the norm (neomorphs, atavisms) - Updates hypotheses on the origination of cartilage using new phylogenetic, cellular and genetic data - Covers stem cells in embryos and adults, including mesenchymal stem cells and their use in genetic engineering of cartilage, and the concept of the stem cell niche
Author: Edward J. Massaro
Publisher: Springer Science & Business Media
ISBN: 159259736X
Category : Medical
Languages : en
Pages : 812
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Book Description
A cutting-edge review of the biochemical, physiological, pharmacological, genetic, and molecular interactions involved in the development and homeostasis of the skeleton. Topics range from chondrogenesis, chondrocytes, and cartilage to skeletal dysmorphology, and include the control of skeletal development, osteoblastic cell differentiation, and bone induction, growth, remodeling, and mineralization. The authors' understanding of bone physiology-and how it is modified throughout all the stages of life-offers novel approaches for improving the endurance of load-bearing implants, achieving life-long optimal bone strength, overcoming microgravity situations (space flight), and hastening the healing of fractures, osteotomies, and antrodeses.
