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Author: M. Z. Atassi
Publisher: Springer Science & Business Media
ISBN: 1468479741
Category : Medical
Languages : en
Pages : 278
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Book Description
This symposia series, founded in 1976, is devoted to the advancement and dissemination of knowledge in the field in immunology, particularly as it relates to the immune recognition and responses to protein and peptide antigens. Leading investigators are convened every 2 or 3 years for the purpose of consolidating the research on protein and peptide antigens of defined structure and to focus on these findings in the context of contemporary immunology. Each symposium has focussed on a particular aspect of molecular and cellular immunology of proteins and peptides. It is extremely gratifying that, in the last 2-3 years, the scientific community has shown a heightened interest in the study and understanding of protein and peptide antigens. The third symposium was devoted to viral and bacterial antigens. Great advances have been made in recent years in the elucidation and synthesis of protein antigenic sites. These, together with advances in cloning, expression and sequencing of protein genes, have offered new avenues for the preparation of synthetic vaccines for viral, bacterial and other antigens. Such vaccines have been the aspiration of immunologists for over 20 years. The meeting has served to integrate and correlate the current knowledge of these systems with developing trends in immunology and to identify the most promising new directions for future investigations.
Author: M. Z. Atassi
Publisher: Springer Science & Business Media
ISBN: 1468479741
Category : Medical
Languages : en
Pages : 278
Get Book Here
Book Description
This symposia series, founded in 1976, is devoted to the advancement and dissemination of knowledge in the field in immunology, particularly as it relates to the immune recognition and responses to protein and peptide antigens. Leading investigators are convened every 2 or 3 years for the purpose of consolidating the research on protein and peptide antigens of defined structure and to focus on these findings in the context of contemporary immunology. Each symposium has focussed on a particular aspect of molecular and cellular immunology of proteins and peptides. It is extremely gratifying that, in the last 2-3 years, the scientific community has shown a heightened interest in the study and understanding of protein and peptide antigens. The third symposium was devoted to viral and bacterial antigens. Great advances have been made in recent years in the elucidation and synthesis of protein antigenic sites. These, together with advances in cloning, expression and sequencing of protein genes, have offered new avenues for the preparation of synthetic vaccines for viral, bacterial and other antigens. Such vaccines have been the aspiration of immunologists for over 20 years. The meeting has served to integrate and correlate the current knowledge of these systems with developing trends in immunology and to identify the most promising new directions for future investigations.
Author: Kenneth Murphy
Publisher: Garland Science
ISBN: 9780815344575
Category : Medical
Languages : en
Pages :
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Book Description
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author: M. Zouhair Atassi
Publisher: Springer Science & Business Media
ISBN: 1468443313
Category : Medical
Languages : en
Pages : 227
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Book Description
The immune response is largely dependent on molecular inter actions involving proteins. The recognition of antigen molecules, whether they are proteins or non-proteins, whether they are self or non-self, takes place at the molecular-cellular interface through membrane receptor molecules that are proteins. The initial step of recognition activates a complex series of cellular events requiring some mechanism of cell-cell interactions and communi cations, eventually leading to antibody production. This biolo gical cascade is controlled at several positions along its con secutive pathways by protein molecules, either in the free form or as receptors on membranes of cells committed to this activity. Clearly, then, the proper understanding of the response by cells of the immune system will depend, to a great measure, on the definition of the molecular events involving protein interactions. Obviously, cells work via molecules and molecules work via cells and, at this level of functional resolution, molecular immunology and cellular immunology will merge and will depend heavily on protein chemistry.
Author: M. Atassi
Publisher: Springer Science & Business Media
ISBN: 1475720467
Category : Medical
Languages : en
Pages : 353
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Book Description
Proceedings of the Fifth International Symposium held in Alberta, Canada, Oct. 1988. Articles are focused on the field of vaccines against viral, bacterial, and parasitic agents. Topics include: cytotoxic and helper T-lymphocyte responses to antibody, the application of molecular biology to the deve
Author: Chaim Putterman
Publisher: Academic Press
ISBN: 0128033703
Category : Medical
Languages : en
Pages : 192
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Book Description
Structural Biology in Immunology, Structure/Function of Novel Molecules of Immunologic Importance delivers important information on the structure and functional relationships in novel molecules of immunologic interest. Due to an increasingly sophisticated understanding of the immune system, the approach to the treatment of many immune-mediated diseases, including multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, and inflammatory bowel disease has been dramatically altered. Furthermore, there is an increasing awareness of the critical role of the immune system in cancer biology. The improved central structure function relationships presented in this book will further enhance our ability to understand what defects in normal individuals can lead to disease. - Describes novel/recently discovered immunomodulatory proteins, including antibodies and co-stimulatory or co-inhibitory molecules - Emphasizes new biologic and small molecule drug design through the exploration of structure-function relationship - Features a collaborative editorial effort, involving clinical immunologists and structural biologists - Provides useful and practical insights on developing the necessary links between basic science and clinical therapy in immunology - Gives interested parties a bridge to learn about computer modeling and structure based design principles
Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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Book Description
Author: M. Zouhair Atassi
Publisher: Springer Science & Business Media
ISBN: 1461518911
Category : Medical
Languages : en
Pages : 281
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Book Description
This volume summarizes the proceedings of the Eighth International Symposium on the Immunobiology of Proteins and Peptides which was held on November 16-20 in Rio Rico, Arizona. The articles represent papers by invited speakers as well as papers selected by the Scientific Council, from among those submitted by the participants, on the basis of quality and timeliness. This symposium series was established in 1976 for the purpose of bringing together, once every two or three years, active investigators in the forefront of contemporary immunology, to present their findings, discuss their significance in the light of current concepts and identify important new directions of investigation. The founding of the symposium was stimulated by the achievement of major breakthroughs in the understanding of the immune recognition of proteins and peptides. We believed that these breakthroughs would lead to the creation of a new generation of peptide reagents, which could have enormous potential in biological, therapeutic, and basic applications. This anticipated explosion has since occurred and many applications ofthese peptides are now being realized. The eighth symposium focused on the manipulation or modulation of the immune response. This volume broadly covers the areas of adjuvants, cytokines, vaccines, and the use of intravenous immunoglobulins for disease management. There is a clear need to identify methods for improving vaccine efficacy and guiding the host to respond with a particular type of immune response.
Author: Muhammad Tufail
Publisher: Bentham Science Publishers
ISBN: 1608054012
Category : Nature
Languages : en
Pages : 191
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Book Description
Recent molecular studies have revealed an overwhelming role of hemolymph proteins and functional peptides in invertebrate physiology. This is mainly due to the large assortment of biomolecular factors each with a different structure and function. In addit
Author: M. Zouhair Atassi
Publisher: Springer Science & Business Media
ISBN: 1461588588
Category : Medical
Languages : en
Pages : 501
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Book Description
One of the central questions in immunology is the understanding in molecular terms of antigen-antibody interactions and of the cellu lar recognition of antigens. It is hoped that this understanding will extend eventually to the immunobiological basis of host defense to infectious agents and of tissue damage or deranged cell functions which stem from these reactions. A variety of natural and artificial substances have been used as models for these studies. Emphasis was placed upon substances of known and relatively uncomplicated chemical structures. These included polysaccharides, amino acid polymers, nu cleic acids and haptens. On the other hand. until recently there has been very little information on protein antigens. The complexity of these molecules posed an immense chemical obstacle to precise immuno chemical analysis. Indeed, it is this difficulty with proteins that spurred the synthesis and immunological studies of amino acid poly mers. The control and normal regulation of the immune system at the cellular-molecular interface and the great majority of antigens asso ciated with immune disorders are attributed to protein molecules. In the last few years great advances have been made in the analysis and synthesis of the antigenic sites of some proteins. The entire antigenic structures of myoglobin and lysozyme and the partial anti genic structures of several other proteins have been determined. Moreover, in the past seven years several biological responses resulting from the reactions of proteins and their peptides with cells of the immune system were described.
Author: Bernd Kaspers
Publisher: Academic Press
ISBN: 0123972728
Category : Medical
Languages : en
Pages : 456
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Book Description
The second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success. The book contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. The world-wide importance of poultry protein for the human diet, as well as the threat of avian influenza pandemics like H5N1 and heavy reliance on vaccination to protect commercial flocks makes this book a vital resource. This book provides crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. - With contributions from 33 of the foremost international experts in the field, this book provides the most up-to-date review of avian immunology so far - Contains a detailed description of the avian innate immune system reviewing constitutive barriers, chemical and cellular responses; it includes a comprehensive review of avian Toll-like receptors - Contains a wide-ranging review of the "ecoimmunology" of free-living avian species, as applied to studies of population dynamics, and reviews methods and resources available for carrying out such research
