Janeway's Immunobiology

Janeway's Immunobiology PDF Author: Kenneth Murphy
Publisher: Garland Science
ISBN: 9780815344575
Category : Medical
Languages : en
Pages :

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Book Description
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Janeway's Immunobiology

Janeway's Immunobiology PDF Author: Kenneth Murphy
Publisher: Garland Science
ISBN: 9780815344575
Category : Medical
Languages : en
Pages :

Get Book Here

Book Description
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Dendritic Cells in Fundamental and Clinical Immunology

Dendritic Cells in Fundamental and Clinical Immunology PDF Author: Paola Ricciardi-Castagnoli
Publisher: Springer Science & Business Media
ISBN: 9780306455926
Category : Medical
Languages : en
Pages : 630

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Book Description
These proceedings contain selected contributions from the participants to the Fourth International Symposium on Dendritic cells that was held in Venice (Lido) Italy, from Oc tober 5 to 10, 1996. The symposium was attended by more than 500 scientists coming from 24 different countries. Studies on dendritic cells (DC) have been greatly hampered by the difficulties in preparing sufficient cell numbers and in a reasonable pure form. At this meeting it has been shown that large quantities of DC can be generated from precursors in both mice and humans, and this possibility has enormously encouraged studies aimed to characterize DC physiology and DC-specific genes, and to employ DC therapeutically as adjuvants for im munization. The possibility of generating large numbers of autologous DC that can be used in the manipulation of the immune response against cancer and infectious diseases has tremendously boosted dendritic cell research and the role of DC in a number of medi cal areas has been heatedly discussed.

Dendritic Cells

Dendritic Cells PDF Author: Michael T. Lotze
Publisher: Elsevier
ISBN: 0080491073
Category : Science
Languages : en
Pages : 851

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Book Description
Dendritic Cells, Second Edition is the new edition of the extremely successful book published in 1998. With the volume of literature on dendritic cells doubling every year, it is almost impossible to keep up. This book provides the most up-to-date synthesis of the literature, written by the very best authors. It is essential reading for any scientist working in immunology, cell biology, infectious diseases, cancer, transplantation, genetic engineering, or the pharmaceutical/biotechnology industry. An entirely new section on DC biology is included in this edition. Also new to this edition are chapters on: Imaging Interaction of dendritic cells with viruses Dendritic cells and dendrikines, chemokines and the endothelium Molecules expressed in dendritic cells Role of dendritic cells in wound healing and atherosclerosis Delivery of apoptotic bodies Genetic engineering of dendritic cells Imaging Practical aspects of clinical protocol development

Dendritic Cell Control of Immune Responses

Dendritic Cell Control of Immune Responses PDF Author: Penelope Anne Morel
Publisher: Frontiers Media SA
ISBN: 2889198685
Category : Dendritic cells
Languages : en
Pages : 123

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Book Description
Dendritic cells (DC) are among the first cells to encounter pathogens and damage in peripheral tissues and, upon activation, DC migrate to lymph nodes where they activate and educate T cells to initiate and shape the immune response. DC present pathogen-derived antigen to T cells and drive T cell differentiation into particular effector cells through the expression and secretion of co-stimulatory molecules and cytokines respectively. The study of DC biology has included the identification of multiple DC subsets in tissues and lymphoid organs, the differentiation and plasticity of DC subsets, the functional consequences of DC interaction with pathogen, control of DC migratory properties and the impact of DC on T cell activation and differentiation. In recent years sophisticated systems biology approaches have been developed to deepen our understanding of DC function. These studies have identified differences between DC subsets located in various tissues and critical factors that drive the outcome of the interaction between DC and T cells. DC are currently being used in in various clinical therapeutic settings, including as vaccines for cancer and autoimmune disease. A clear understanding of DC factors that contribute to specific immune responses is vital to the success of DC based therapies. This research topic will give a comprehensive overview of current issues in DC biology and provides an update on the clinical uses of DC in the therapy of autoimmunity and cancer.

Immunobiology of Dendritic Cells

Immunobiology of Dendritic Cells PDF Author: Jeremy Collins
Publisher: American Medical Publishers
ISBN:
Category : Medical
Languages : en
Pages : 0

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Book Description
Dendritic cells (DCs) refer to antigen-presenting cells of the mammalian immune system. The major job of the dendritic cells is to process antigen material and present it on the cell surface to the T cells of the immune system. They serve as messengers among the adaptive and innate immune systems. Dendritic cells are found in those tissues that come contact with the external environment, such as the skin and the inner lining of the stomach, nose, intestines and lungs. They can also be detected in the blood in an immature form. Dendritic cells are obtained from hematopoietic bone marrow progenitor cells, which first develop into immature dendritic cells and communicate continuously with other cells in the body. The communication can occur in the form of direct cell-cell contact on the basis of interaction between cell-surface proteins. This book aims to understand the immunobiology of dendritic cells. The topics included herein are of utmost significance and bound to provide incredible insights to the readers. Researchers and students engaged in the study of dendritic cells will be assisted by this book.

Harnessing the Participation of Dendritic Cells in Immunity and Tolerance

Harnessing the Participation of Dendritic Cells in Immunity and Tolerance PDF Author: Silvia Beatriz Boscardin
Publisher: Frontiers Media SA
ISBN: 2889662012
Category : Medical
Languages : en
Pages : 511

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Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Immunobiology of Dendritic Cells Part B

Immunobiology of Dendritic Cells Part B PDF Author:
Publisher: Academic Press
ISBN: 9780128183571
Category : Science
Languages : en
Pages : 0

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Book Description
Immunobiology of Dendritic Cells Part B, Volume 349 in the International Review of Cell and Molecular Biology series highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

Dendritic Cells in Fundamental and Clinical Immunology

Dendritic Cells in Fundamental and Clinical Immunology PDF Author: Jacques Banchereau
Publisher: Springer Science & Business Media
ISBN: 1461519713
Category : Medical
Languages : en
Pages : 493

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Book Description
These Proceedings contain the contributions of the partIcIpants of the Third International Symposium on Dendritic Cells that was held in Annecy, France, from June 19 to June 24, 1994. This symposium represented a follow-up of the first and second international symposia that were held in Japan in 1990 and in the Netherlands in 1992. Dendritic cells are antigen-presenting cells, and are found in all tissues and organs of the body. They can be classified into: (1) interstitial dendritic cells of the heart, kidney, gut, and lung;(2) Langerhans cells in the skin and mucous membranes; (3) interdigitating dendritic cells in the thymic medulla and secondary lymphoid tissue; and (4) blood dendritic cells and lymph dendritic cells (veiled cells). Although dendritic cells in each of these compartments are all CD45+ leukocytes that arise from the bone marrow, they may exhibit differences that relate to maturation state and microenvironment. Dendritic cells are specialized antigen-presenting cells for T lymphocytes: they process and present antigens efficiently in situ, and stimulate responses from naive and memory T cells in the paracortical area of secondary lymphoid organs. Recent evidence also demonstrates their role in induction of tolerance. By contrast, the primary and secondary B-cell follicles contain follicular dendritic cells that trap and retain intact antigen as immune complexes for long periods of time. The origin of follicular dendritic cells is not clear, but most investigators believe that these cells are not leukocytes.

Molecular Mechanisms of Dendritic Cell-Mediated Immune Tolerance and Autoimmunity

Molecular Mechanisms of Dendritic Cell-Mediated Immune Tolerance and Autoimmunity PDF Author: Fang Zhou
Publisher: Frontiers Media SA
ISBN: 2832547702
Category : Medical
Languages : en
Pages : 213

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Book Description
Dendritic cells (DCs) play a critical role in immune system, as they are necessary both for innate and adaptive immunity. According to their function, dendritic cells can be classified in immune tolerogenic or inflammatory DCs. DCs have been shown to regulate T cell-mediated immune responses and lead to immune tolerance and autoimmunity. For example, immune-tolerogenic DCs facilitate the development of regulatory T cells and inhibit T helper 17-mediated autoimmunity in mice with experimental autoimmune encephalomyelitis. Moreover, inflammatory DCs activate CD8+ and CD4+ T cells and elicit T cell-mediated inflammatory immune responses in vivo. However, the molecular and cellular mechanisms underlying DC-mediated immune tolerance and autoimmunity are still obscure.

Dendritic Cells in Clinics

Dendritic Cells in Clinics PDF Author: Morikazu Onji
Publisher: Springer Science & Business Media
ISBN: 4431670114
Category : Medical
Languages : en
Pages : 196

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Book Description
Great advances have taken place in basic research and the clinical usefulness of dendritic cells (DCs). It has now been clearly established, for instance, that these cells play a crucial role in immune responses against infectious diseases and cancers. Antigen-presenting DCs are widely distributed in the body and regulate both immunity and immune tolerance. Experimental studies have provided important insights into DCs and how they can be used for treating animal models of various diseases that occur in humans. The role of these cells in pathogenesis and the treatment of human diseases is elaborately set forth in this valuable book. Researchers in the field are optimistic that DCs, already in use for treating patients with cancers, soon can be used therapeutically for patients with chronic infections, autoimmune diseases, and allergic manifestations. This volume provides a working definition of DCs and also explains the phenotypes and functions of DCs so that these can be readily understood not only by clinicians but by immunologists, researchers, and students as well.