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Author: Jeanette M. van Emon
Publisher: CRC Press
ISBN: 1420020692
Category : Medical
Languages : en
Pages : 532
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Book Description
Taking an interdisciplinary approach that emphasizes the adaptability of immunochemical and related bioanalytical methods to a variety of matrices, Immunoassay and Other Bioanalytical Techniques describes the strength and the versatility of these methods in a wide range of environmental and biological measurement applications. With contribut
Author: Jeanette M. van Emon
Publisher: CRC Press
ISBN: 1420020692
Category : Medical
Languages : en
Pages : 532
Get Book Here
Book Description
Taking an interdisciplinary approach that emphasizes the adaptability of immunochemical and related bioanalytical methods to a variety of matrices, Immunoassay and Other Bioanalytical Techniques describes the strength and the versatility of these methods in a wide range of environmental and biological measurement applications. With contribut
Author: Sandeep K. Vashist
Publisher: Academic Press
ISBN: 012811794X
Category : Medical
Languages : en
Pages : 498
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Book Description
Handbook of Immunoassay Technologies: Approaches, Performances, and Applications unravels the role of immunoassays in the biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, ranging from the conventional enzyme-linked immunosorbent assays, to the smartphone-based point-of-care formats. The advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, device miniaturization and interfacing, and emerging smart system technologies equipped with personalized mobile healthcare tools are paving the way to next-generation immunoassays, and are all discussed in this comprehensive text. Immunoassays play a prominent role in clinical diagnostics as they are the eyes of healthcare professionals, helping them make informed clinical decisions via confirmed disease diagnosis, and thus enabling favorable health outcomes. The faster and reliable diagnosis of infections will further control their spread to uninfected persons. Similarly, immunoassays play a prominent role in veterinary diagnostics, food analysis, environmental monitoring, defense and security, and other bioanalytical settings. Therefore, they enable the detection of a plethora of analytes, which includes disease biomarkers, pathogens, drug impurities, environmental contaminants, allergens, food adulterants, drugs of abuse and various biomolecules. - Provides a valuable increase of understanding of cellular and biomedical functions - Gives the most updated resource in the field of immunoassays, providing the comprehensive details of various types of immunoassays that need to be performed in healthcare, and in industrial, environmental and other biochemical settings - Discusses all multifarious aspects of immunoassays - Describes the immunoassay formats, along with their principle of operation, characteristics, pros and cons, and potential biochemical and bioanalytical applications - Provides extensive knowledge and guided insights as detailed by experienced, renowned experts and key opinion makers in the field of immunoassays
Author: D. M. Kemeny
Publisher: John Wiley & Sons
ISBN: 9780471909828
Category : Science
Languages : en
Pages : 384
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Book Description
This is a quick-reference manual on practical aspects of immunoassay. Providing a theoretical and practical basis for modern applications of solid-phase immunoassays, this text brings together experts who have used ELISA and other assays in a variety of fields. Contributors offer step-by-step guidance on how to use the various techniques involved in immunoassay. These techniques are extemely useful to laboratory-based researchers and technicians working on the detection of allergy, the AIDS virus, autoimmunity, etc. Chapters analyze the solid-phase supports used, the amplification systems, and the quantitation and affinity of antibodies and discuss the applications of assays to biology, immunology, and microbiology.
Author: Richard F. Venn
Publisher: CRC Press
ISBN: 9780748408429
Category : Medical
Languages : en
Pages : 392
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Book Description
Principles and Practice of Bioanalysis provides a guide to the methods available and the techniques currently used in this field. It provides up to the minute information and guidance on the methods and strategy used in developing and running ultra-trace analyses for drugs, metabolites and other substances. The authors writes in an informal and didactic style, offering a logical path through the problems of small molecule (bio)analysis and enables readers to choose appropriate methods of analysis for their needs. Principles and Practice of Bioanalysis provides an overview of analytical methods for analytical scientists within the pharmaceutical industry, research and development, the agrochemical industry, and scientists in the health service, biology and biochemistry. It also gives postgraduate students a useful reference for their research methods.
Author: Abhilasha Shourie
Publisher: The Energy and Resources Institute (TERI)
ISBN: 8179935299
Category : Science
Languages : en
Pages : 424
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Book Description
Bioanalytical Techniques form an integral part of applied biology and biomedical sciences. The various principles of bioanalytical techniques used in biomedical sciences, environmental studies, life sciences, pharmaceutical analysis, molecular biology, and biotechnological research are comprehensively discussed in this book. Analytical instrumentation is also explained in as concise a manner as possible. Microscopy, centrifugation, chromatography, electrophoresis, spectroscopy, and radioisotope and immunodiagnostic techniques are the main topics focussed in this book. Techniques in molecular biology and recombinant DNA technology have also been described in detail.
Author: Susan R. Mikkelsen
Publisher: John Wiley & Sons
ISBN: 1118302540
Category : Science
Languages : en
Pages : 488
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Book Description
A timely, accessible survey of the multidisciplinary field of bioanalytical chemistry Provides an all in one approach for both beginners and experts, from a broad range of backgrounds, covering introductions, theory, advanced concepts and diverse applications for each method Each chapter progresses from basic concepts to applications involving real samples Includes three new chapters on Biomimetic Materials, Lab-on-Chip, and Analytical Methods Contains end-of-chapter problems and an appendix with selected answers
Author: Wenkui Li
Publisher: John Wiley & Sons
ISBN: 111927429X
Category : Science
Languages : en
Pages : 384
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Book Description
Revised and Expanded Handbook Provides Comprehensive Introduction and Complete Instruction for Sample Preparation in Vital Category of Bioanalysis Following in the footsteps of the previously published Handbook of LC-MS Bioanalysis, this book is a thorough and timely guide to all important sample preparation techniques used for quantitative Liquid Chromatography–Mass Spectrometry (LC-MS) bioanalysis of small and large molecules. LC-MS bioanalysis is a key element of pharmaceutical research and development, post-approval therapeutic drug monitoring, and many other studies used in human healthcare. While advances are continually being made in key aspects of LC-MS bioanalysis such as sensitivity and throughput, the value of research/study mentioned above is still heavily dependent on the availability of high-quality data, for which sample preparation plays the critical role. Thus, this text provides researchers in industry, academia, and regulatory agencies with detailed sample preparation techniques and step-by-step protocols on proper extraction of various analyte(s) of interest from biological samples for LC-MS quantification, in accordance with current health authority regulations and industry best practices. The three sections of the book with a total of 26 chapters cover topics that include: Current basic sample preparation techniques (e.g., protein precipitation, liquid-liquid extraction, solid-phase extraction, salting-out assisted liquid-liquid extraction, ultracentrifugation and ultrafiltration, microsampling, sample extraction via electromembranes) Sample preparation techniques for uncommon biological matrices (e.g., tissues, hair, skin, nails, bones, mononuclear cells, cerebrospinal fluid, aqueous humor) Crucial aspects of LC-MS bioanalytical method development (e.g., pre-analytical considerations, derivation strategies, stability, non-specific binding) in addition to sample preparation techniques for challenging molecules (e.g., lipids, peptides, proteins, oligonucleotides, antibody-drug conjugates) Sample Preparation in LC-MS Bioanalysis will prove a practical and highly valuable addition to the reference shelves of scientists and related professionals in a variety of fields, including pharmaceutical and biomedical research, mass spectrometry, and analytical chemistry, as well as practitioners in clinical pharmacology, toxicology, and therapeutic drug monitoring.
Author: Leo M. L. Nollet
Publisher: John Wiley & Sons
ISBN: 0470276525
Category : Technology & Engineering
Languages : en
Pages : 386
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Book Description
Food diagnostics is a relatively new and emerging area fuelled inlarge part by the ever-increasing demand for food safety.Advances in Food Diagnostics provides the most updated,comprehensive professional reference source available, coveringsophisticated diagnostic technology for the food industry. EditorsNollet, Toldrá, and Hui and their broad team of internationalcontributors address the most recent advances in food diagnosticsthrough multiple approaches: reviewing novel technologies toevaluate fresh products; describing and analyzing in depth severalspecific modern diagnostics; providing an analysis of dataprocessing; and discussing global marketing with an insight intofuture trends. While covering conventional (typically lab-based) methods ofanalysis, the book focuses on leading-edge technologies that arebeing or about to be introduced. The book looks at areas such asfood quality assurance, safety and traceability. Issues such asimproved quality control, monitoring pesticide and herbicideresidues in food, determining the nutritional content of food anddistinguishing between GM and "conventional" foodstuffs arecovered. Advances in Food Diagnostics offers the foodprofessional what its title promises – the latest advances infood diagnostics and analysis.
Author: Sekhar Talluri
Publisher: Techsar Pvt. Ltd
ISBN: 9381141703
Category : Medical
Languages : en
Pages : 269
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Book Description
This book describes the principles of the bioanalytical techniques that are used in clinical diagnosis, pharmaceutical analysis, bioprocess monitoring, environmental studies and life sciences research. The primary focus of this book is on instrumental methods which are evolving rapidly due to the availability of new technologies. The basic concepts of each technique are explained in as concise and simple a manner as possible, without sacrificing generality or rigour. Part-I and Part-II are primarily for undergraduate students. Part-I describes analytical methods that are based on the separation of particles (chromatography, electrophoresis, mass spectrometry, etc). Part-II describes methods based on spectroscopy, scattering and diffraction. Part-III introduces some basic biochemical and molecular biological methods such as binding assays, PCR, protein sequencing and nucleic acid sequencing and is intended as background material for students who are interested in the topics described in Part-IV. Part-IV describes the basic concepts of novel micro- and nano-bioanalytical techniques which are based on biosensors, microarrays, microfluidics, surface plasmon resonance and nanomaterials. Part-IV is primarily for postgraduate students. However, adequate basics are provided to ensure that advanced undergraduates can also benefit from this section.
Author: Lisa K. Minor
Publisher: CRC Press
ISBN: 1420015702
Category : Medical
Languages : en
Pages : 490
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Book Description
The Handbook of Assay Development in Drug Discovery describes all the tools currently available for performing various assay techniques. Featuring troubleshooting advice for common problems from experienced assay developers, the vendor community, and scientists in the pharmaceutical industry, the book presents descriptions of methods, laboratory guidelines and protocols used to perform such methods, specific examples of each assay system, and troubleshooting tools. Designed as a guide to running an assay from start to finish, this is an ideal bench top companion for scientists involved in drug discovery screening, lead profiling, therapeutic target evaluation, and assay development and implementation.
