Immune Modulation in Tumor Microenvironment: New Perspectives for Cancer Immunotherapy

Immune Modulation in Tumor Microenvironment: New Perspectives for Cancer Immunotherapy PDF Author: Qian Xiao
Publisher: Frontiers Media SA
ISBN: 2832513344
Category : Science
Languages : en
Pages : 303

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Book Description

Immune Modulation in Tumor Microenvironment: New Perspectives for Cancer Immunotherapy

Immune Modulation in Tumor Microenvironment: New Perspectives for Cancer Immunotherapy PDF Author: Qian Xiao
Publisher: Frontiers Media SA
ISBN: 2832513344
Category : Science
Languages : en
Pages : 303

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Book Description


Tertiary Lymphoid Structures

Tertiary Lymphoid Structures PDF Author: Marie-Caroline Dieu-Nosjean
Publisher: Humana Press
ISBN: 9781493987085
Category : Medical
Languages : en
Pages : 289

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Book Description
This volume explores the various methods used to study tertiary lymphoid structures (TLS) in pathological situations. Pre-clinical models are also discussed in detail to show how TLS structure, development, and maintenance can be targeted and studied in vivo. The chapters in this book cover topics such as humans and mice; strategies to quantify TLS in order to use it in stained tissue sections; classifying a gene signature form fixed and paraffin-embedded tissues; and development of murine inflammatory models to help look at TLS in the context of infection or malignancy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Tertiary Lymphoid Structures: Methods and Protocols is a valuable resource that increases the reader’s knowledge on immune functions and how they will pave the way to future therapeutic applications.

Immunotherapy in Resistant Cancer: From the Lab Bench Work to Its Clinical Perspectives

Immunotherapy in Resistant Cancer: From the Lab Bench Work to Its Clinical Perspectives PDF Author: Jorge Morales-Montor
Publisher: Academic Press
ISBN: 0128220287
Category : Science
Languages : en
Pages : 286

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Book Description
Immunotherapy in Resistant Cancer: From the Lab Bench Work to Its Clinical Perspectives provides high level knowledge on detailed mechanisms of actions and biological interactions of different immune drugs, with an aim of offering researchers and clinicians cutting-edge therapies to overcome drug resistance. The book explains the latest immunotherapies for different types of cancer, helping users carry out research projects or create alternatives for drug development in the pharmaceutical industry. Topics discussed include the relationship between immunotherapy and macrophages, immune checkpoints in different types of cancer, immune cocktails in solid tumors, and immune-phenotyping. Additionally, the book presents basic and clinical data on immunoresistance and glycosylation. This book is a valuable source for cancer researchers, medical doctors, clinicians and members of the biomedical field who must understand certain mechanisms to fight cancer that is resistant to immunotherapy.

General Principles of Tumor Immunotherapy

General Principles of Tumor Immunotherapy PDF Author: Howard L. Kaufman
Publisher: Springer Science & Business Media
ISBN: 1402060874
Category : Medical
Languages : en
Pages : 502

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Book Description
This book brings together the world’s leading authorities on tumor immunology. This book describes the basic immunology principles that form the foundation of understanding how the immune system recognizes and rejects tumor cells. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated.

Progress in Cancer Immunotherapy

Progress in Cancer Immunotherapy PDF Author: Shuren Zhang
Publisher: Springer
ISBN: 9401775559
Category : Medical
Languages : en
Pages : 293

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Book Description
This book provides readers an extensive overview of recent progress in basic and clinical research on cancer immunotherapy. Thanks to rapid advances in molecular biology and immunology, it has become increasingly evident that cancer growth is influenced by host immune responses. With the success of a number of clinical trials, immunotherapy has become a promising treatment modality of cancer. This book covers five major topics, including monoclonal antibodies, biological response modifiers, cancer vaccines, adoptive cellular therapy and oncolytic viruses. It also examines the combination of different immune strategies as well as the combination of immunotherapy with other treatments to increase anti-tumor effects. Through the comprehensive discussion of the topic, the book sheds valuable new light on the treatment of tumors.

Immune Checkpoint Inhibitors in Cancer

Immune Checkpoint Inhibitors in Cancer PDF Author: Fumito Ito
Publisher: Elsevier Health Sciences
ISBN: 0323549500
Category : Medical
Languages : en
Pages : 271

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Book Description
Get a quick, expert overview of the latest clinical information and guidelines for cancer checkpoint inhibitors and their implications for specific types of cancers. This practical title by Drs. Fumito Ito and Marc Ernstoff synthesizes the most up-to-date research and clinical guidance available on immune checkpoint inhibitors and presents this information in a compact, easy-to-digest resource. It's an ideal concise reference for trainee and practicing medical oncologists, as well as those in research. - Discusses the current understanding of how to best harness the immune system against different types of cancer at various stages. - Helps you translate current research and literature into practical information for daily practice. - Presents information logically organized by disease site. - Covers tumor immunology and biology; toxicities associated with immune checkpoint inhibitors; and future outlooks. - Consolidates today's available information on this timely topic into one convenient resource.

Tumor Immunology and Immunotherapy

Tumor Immunology and Immunotherapy PDF Author: Robert C. Rees
Publisher: Oxford University Press, USA
ISBN: 0199676860
Category : Medical
Languages : en
Pages : 469

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Book Description
Tumor immunology and immunotherapy provides a comprehensive account of cancer immunity and immunotherapy. Examining recent results, current areas of interest and the specific issues that are affecting the research and development of vaccines, this book provides insight into how these problems may be overcome as viewed by leaders in the field.

Immunotherapy in Translational Cancer Research

Immunotherapy in Translational Cancer Research PDF Author: Laurence J. N. Cooper
Publisher: John Wiley & Sons
ISBN: 1118123220
Category : Medical
Languages : en
Pages : 306

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Book Description
A guide to state-of-the-art cancer immunotherapy in translational cancer research A volume in the Translational Oncology series, Immunotherapy in Translational Cancer Research explores the recent developments in the role that immunotherapy plays in the treatment of a wide range of cancers. The editors present key concepts, illustrative examples, and suggest alternative strategies in order to achieve individualized targeted therapy. Comprehensive in scope, Immunotherapy in Translational Cancer Research reviews the relevant history, current state, and the future of burgeoning cancer-fighting therapies. The book also includes critical information on drug development, clinical trials, and governmental resources and regulatory issues. Each chapter is created to feature: development of the immunotherapy; challenges that have been overcome in order to scale up and undertake clinical trials; and clinical experience and application of research. This authoritative volume is edited by a team of noted experts from MD Anderson Cancer Center, the world’s foremost cancer research and care center and: Offers a comprehensive presentation of state-of-the-art cancer immunotherapy research that accelerates the pace of clinical cancer care Filled with the concepts, examples, and approaches for developing individualized therapy Explores the breath of treatments that reflect the complexity of the immune system itself Includes contributions from a panel international experts in the field of immunotherapy Designed for physicians, medical students, scientists, pharmaceutical executives, public health and public policy government leaders and community oncologists, this essential resource offers a guide to the bidirectional interaction between laboratory and clinic immunotherapy cancer research.

Polysaccharide Carriers for Drug Delivery

Polysaccharide Carriers for Drug Delivery PDF Author: Sabyasachi Maiti
Publisher: Woodhead Publishing
ISBN: 0081025548
Category : Technology & Engineering
Languages : en
Pages : 804

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Book Description
Polysaccharide Carriers for Drug Delivery presents the latest information on the selection of safe materials. Due to reported safety profiles on polysaccharides; they have been the natural choice for investigation. A wide variety of drug delivery and biomedical systems have been studied, however, the related information either concept-wise or application-oriented is scattered, therefore becoming difficult for readers and researchers to digest in a concise manner. This gathering of information will help readers easily comprehend the subject matter. - Focuses on biopolysaccharide-based, distinct approaches for drug delivery applications - Illustrates new concepts and highlights future scope for clinical development - Provides comprehensive, up-to-date information on different aspects of drug delivery technology

Cell Press Reviews: Cancer Therapeutics

Cell Press Reviews: Cancer Therapeutics PDF Author: Cell Press
Publisher: Elsevier
ISBN: 0127999175
Category : Medical
Languages : en
Pages : 323

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Book Description
Cell Press Reviews: Cancer Therapeutics informs, inspires, and connects cancer researchers at all stages in their careers with timely, comprehensive reviews written by leaders in the field and curated by Cell Press editors. The publicatio offers a broad view of some of the most compelling topics in cancer therapeutics including: - Genetic approaches for personal oncology - Targeting epigenetic dysregulation and protein interaction networks - Vaccines and antibodies in cancer immunotherapy - Tumor heterogeneity and chemotherapy resistance - Tumor associated macrophages in anticancer treatment Contributions come from leading voices in the field, including: - Daniel A. Haber, Director of Massachusetts General Hospital Cancer Center and Professor at Harvard Medical School - Tony Kouzarides, Professor at the University of Cambridge, Deputy Director of the Wellcome Trust/Cancer Research UK Gurdon Institute, and a founder of the cancer drug discovery company Chroma Therapeutics - Charles L. Sawyers, Chair of the Human Oncology and Pathogenesis Program at Memorial Sloan Kettering Cancer Center, President of the American Association for Cancer Research, member of the presidentially appointed National Cancer Advisory Board, and recipient of the 2013 Breakthrough Prize in Life Sciences Cell Press Reviews: Cancer Therapeutics is part of the Cell Press Reviews series, which features reviews published in Cell Press primary research and Trends reviews journals. - Provides timely, comprehensive articles on a wide range of topics in cancer therapeutics - Offers insight from experts on genetic, molecular, and cellular aspects of cancer therapy - Features reviews on basic science advances translated into drug discovery and therapeutic approaches - Includes articles originally published in Cell, Cancer Cell, Trends in Genetics, Trends in Molecular Medicine, and Trends in Pharmacological Sciences