Author:
Publisher:
ISBN:
Category : Australia
Languages : en
Pages : 1180
Book Description
Australian National Bibliography
Author:
Publisher:
ISBN:
Category : Australia
Languages : en
Pages : 1180
Book Description
Publisher:
ISBN:
Category : Australia
Languages : en
Pages : 1180
Book Description
Proteases: Structure and Function
Author: Klaudia Brix
Publisher: Springer Science & Business Media
ISBN: 3709108853
Category : Science
Languages : en
Pages : 568
Book Description
Proteolysis is an irreversible posttranslational modification affecting each and every protein from its biosynthesis to its degradation. Limited proteolysis regulates targeting and activity throughout the lifetime of proteins. Balancing proteolysis is therefore crucial for physiological homeostasis. Control mechanisms include proteolytic maturation of zymogens resulting in active proteases and the shut down of proteolysis by counteracting endogenous protease inhibitors. Beyond the protein level, proteolytic enzymes are involved in key decisions during development that determine life and death – from single cells to adult individuals. In particular, we are becoming aware of the subtle role that proteases play in signaling events within proteolysis networks, in which the enzymes act synergistically and form alliances in a web-like fashion. Proteases come in different flavors. At least five families of mechanistically distinct enzymes and even more inhibitor families are known to date, many family members are still to be studied in detail. We have learned a lot about the diversity of the about 600 proteases in the human genome and begin to understand their physiological roles in the degradome. However, there are still many open questions regarding their actions in pathophysiology. It is in this area where the development of small molecule inhibitors as therapeutic agents is extremely promising. Approaching proteolysis as the most important, irreversible post-translational protein modification essentially requires an integrated effort of complementary research disciplines. In fact, proteolytic enzymes seem as diverse as the scientists working with these intriguing proteins. This book reflects the efforts of many in this exciting field of research where team and network formations are essential to move ahead.
Publisher: Springer Science & Business Media
ISBN: 3709108853
Category : Science
Languages : en
Pages : 568
Book Description
Proteolysis is an irreversible posttranslational modification affecting each and every protein from its biosynthesis to its degradation. Limited proteolysis regulates targeting and activity throughout the lifetime of proteins. Balancing proteolysis is therefore crucial for physiological homeostasis. Control mechanisms include proteolytic maturation of zymogens resulting in active proteases and the shut down of proteolysis by counteracting endogenous protease inhibitors. Beyond the protein level, proteolytic enzymes are involved in key decisions during development that determine life and death – from single cells to adult individuals. In particular, we are becoming aware of the subtle role that proteases play in signaling events within proteolysis networks, in which the enzymes act synergistically and form alliances in a web-like fashion. Proteases come in different flavors. At least five families of mechanistically distinct enzymes and even more inhibitor families are known to date, many family members are still to be studied in detail. We have learned a lot about the diversity of the about 600 proteases in the human genome and begin to understand their physiological roles in the degradome. However, there are still many open questions regarding their actions in pathophysiology. It is in this area where the development of small molecule inhibitors as therapeutic agents is extremely promising. Approaching proteolysis as the most important, irreversible post-translational protein modification essentially requires an integrated effort of complementary research disciplines. In fact, proteolytic enzymes seem as diverse as the scientists working with these intriguing proteins. This book reflects the efforts of many in this exciting field of research where team and network formations are essential to move ahead.
Geological Survey Water-supply Paper
Author: Geological Survey (U.S.)
Publisher:
ISBN:
Category : Irrigation
Languages : en
Pages : 798
Book Description
Publisher:
ISBN:
Category : Irrigation
Languages : en
Pages : 798
Book Description
Isotopes and Radiation Technology
Author:
Publisher:
ISBN:
Category : Isotopes
Languages : en
Pages : 792
Book Description
Publisher:
ISBN:
Category : Isotopes
Languages : en
Pages : 792
Book Description
Nuclear Science Abstracts
Author:
Publisher:
ISBN:
Category : Nuclear energy
Languages : en
Pages : 1590
Book Description
Publisher:
ISBN:
Category : Nuclear energy
Languages : en
Pages : 1590
Book Description
Journal of the Institute of Petroleum
Author: Institute of Petroleum (Great Britain)
Publisher:
ISBN:
Category : Petroleum
Languages : en
Pages : 342
Book Description
Publisher:
ISBN:
Category : Petroleum
Languages : en
Pages : 342
Book Description
The Electronics of Radio
Author: David Rutledge
Publisher: Cambridge University Press
ISBN: 9780521646451
Category : Technology & Engineering
Languages : en
Pages : 460
Book Description
This fascinating book provides a stimulating introduction to analog electronics by analysing the design and construction of a radio transceiver. Essential theoretical background is given along with carefully designed laboratory and homework exercises. The author begins with a thorough description of basic electronic components and simple circuits and goes on to describe the key elements of radio electronics, including filters, amplifiers, oscillators, mixers, and antennas. Laboratory exercises lead the reader through the design, construction, and testing of a popular radio transceiver (the NorCal 40A). A diskette containing the widely known circuit simulation software, Puff, is included in the book. This was the first book to deal with elementary electronics in the context of radio. It can be used as a textbook for introductory analog electronics courses, for more advanced undergraduate classes on radio-frequency electronics, and will also be of great interest to electronics hobbyists and radio enthusiasts.
Publisher: Cambridge University Press
ISBN: 9780521646451
Category : Technology & Engineering
Languages : en
Pages : 460
Book Description
This fascinating book provides a stimulating introduction to analog electronics by analysing the design and construction of a radio transceiver. Essential theoretical background is given along with carefully designed laboratory and homework exercises. The author begins with a thorough description of basic electronic components and simple circuits and goes on to describe the key elements of radio electronics, including filters, amplifiers, oscillators, mixers, and antennas. Laboratory exercises lead the reader through the design, construction, and testing of a popular radio transceiver (the NorCal 40A). A diskette containing the widely known circuit simulation software, Puff, is included in the book. This was the first book to deal with elementary electronics in the context of radio. It can be used as a textbook for introductory analog electronics courses, for more advanced undergraduate classes on radio-frequency electronics, and will also be of great interest to electronics hobbyists and radio enthusiasts.
Nuclear Science Abstracts
Author:
Publisher:
ISBN:
Category : Nuclear energy
Languages : en
Pages : 872
Book Description
Publisher:
ISBN:
Category : Nuclear energy
Languages : en
Pages : 872
Book Description
The Packet Radio Handbook
Author: Jonathan L. Mayo
Publisher: Tab Books
ISBN: 9780830632220
Category : Crafts & Hobbies
Languages : en
Pages : 228
Book Description
A manual for amateur radio enthusiasts discusses the history of packet radio, hardware systems, networking, setting up an amateur packet radio station, and equipment and accessories
Publisher: Tab Books
ISBN: 9780830632220
Category : Crafts & Hobbies
Languages : en
Pages : 228
Book Description
A manual for amateur radio enthusiasts discusses the history of packet radio, hardware systems, networking, setting up an amateur packet radio station, and equipment and accessories
Amateur Radio Techniques
Author: John Patrick Hawker
Publisher:
ISBN:
Category : Radio
Languages : en
Pages : 160
Book Description
Publisher:
ISBN:
Category : Radio
Languages : en
Pages : 160
Book Description