Author: Fred E. Hahn
Publisher: Springer Science & Business Media
ISBN: 3642464076
Category : Medical
Languages : en
Pages : 484
Book Description
When Antibiotics I was published in 1967, the teleological view was held by some that" antibiotics" were substances elaborated by certain microorgan isms for the purpose of competing with other microorganisms for survival in mixed ecological environments. However, not only had J. EHRLICH and his associates shown 15 years earlier that chloramphenicol was produced by Strepto myces venezuelae in cultures of sterilized soils but not in parallel cultures of the same soils which were not sterilized, but operationally, the search for anti cancer antibiotics was actively under way (Antibiotics I reporting on numerous such substances), although the concept of antibiosis could not logically justify such undertakings. This editor hesitates to accept the use of the term "antibiotic" for anti microbial agents of non microbiological origins which is sometimes encountered, but neither does he subscribe to the view that antibiotics are in some fundamental manner different from chemotherapeutic substances of other origins. Modes and mechanisms of action of chemotherapeutic compounds are not systematic functions of their origins nor of the taxonomical position of the target organisms. Consequently, in the selection of topics for Antibiotics III (published in 1975), synthetic drugs and natural products of higher plants (alkaloids) were represented, along with antibiotics in the strict sense of the definition. We now present Antibiotics V, for whose assembly the same selection criteria were applied as for Antibiotics Ill. The aggregate length of the contributions rendered it impractical to place the entire text between the covers of one book.
Mechanism of Action of Antieukaryotic and Antiviral Compounds
Author: Fred E. Hahn
Publisher: Springer Science & Business Media
ISBN: 3642464076
Category : Medical
Languages : en
Pages : 484
Book Description
When Antibiotics I was published in 1967, the teleological view was held by some that" antibiotics" were substances elaborated by certain microorgan isms for the purpose of competing with other microorganisms for survival in mixed ecological environments. However, not only had J. EHRLICH and his associates shown 15 years earlier that chloramphenicol was produced by Strepto myces venezuelae in cultures of sterilized soils but not in parallel cultures of the same soils which were not sterilized, but operationally, the search for anti cancer antibiotics was actively under way (Antibiotics I reporting on numerous such substances), although the concept of antibiosis could not logically justify such undertakings. This editor hesitates to accept the use of the term "antibiotic" for anti microbial agents of non microbiological origins which is sometimes encountered, but neither does he subscribe to the view that antibiotics are in some fundamental manner different from chemotherapeutic substances of other origins. Modes and mechanisms of action of chemotherapeutic compounds are not systematic functions of their origins nor of the taxonomical position of the target organisms. Consequently, in the selection of topics for Antibiotics III (published in 1975), synthetic drugs and natural products of higher plants (alkaloids) were represented, along with antibiotics in the strict sense of the definition. We now present Antibiotics V, for whose assembly the same selection criteria were applied as for Antibiotics Ill. The aggregate length of the contributions rendered it impractical to place the entire text between the covers of one book.
Publisher: Springer Science & Business Media
ISBN: 3642464076
Category : Medical
Languages : en
Pages : 484
Book Description
When Antibiotics I was published in 1967, the teleological view was held by some that" antibiotics" were substances elaborated by certain microorgan isms for the purpose of competing with other microorganisms for survival in mixed ecological environments. However, not only had J. EHRLICH and his associates shown 15 years earlier that chloramphenicol was produced by Strepto myces venezuelae in cultures of sterilized soils but not in parallel cultures of the same soils which were not sterilized, but operationally, the search for anti cancer antibiotics was actively under way (Antibiotics I reporting on numerous such substances), although the concept of antibiosis could not logically justify such undertakings. This editor hesitates to accept the use of the term "antibiotic" for anti microbial agents of non microbiological origins which is sometimes encountered, but neither does he subscribe to the view that antibiotics are in some fundamental manner different from chemotherapeutic substances of other origins. Modes and mechanisms of action of chemotherapeutic compounds are not systematic functions of their origins nor of the taxonomical position of the target organisms. Consequently, in the selection of topics for Antibiotics III (published in 1975), synthetic drugs and natural products of higher plants (alkaloids) were represented, along with antibiotics in the strict sense of the definition. We now present Antibiotics V, for whose assembly the same selection criteria were applied as for Antibiotics Ill. The aggregate length of the contributions rendered it impractical to place the entire text between the covers of one book.
The Abel Prize 2013-2017
Author: Helge Holden
Publisher: Springer
ISBN: 3319990284
Category : Mathematics
Languages : en
Pages : 762
Book Description
The book presents the winners of the Abel Prize in mathematics for the period 2013–17: Pierre Deligne (2013); Yakov G. Sinai (2014); John Nash Jr. and Louis Nirenberg (2015); Sir Andrew Wiles (2016); and Yves Meyer (2017). The profiles feature autobiographical information as well as a scholarly description of each mathematician’s work. In addition, each profile contains a Curriculum Vitae, a complete bibliography, and the full citation from the prize committee. The book also includes photos for the period 2003–2017 showing many of the additional activities connected with the Abel Prize. As an added feature, video interviews with the Laureates as well as videos from the prize ceremony are provided at an accompanying website (http://extras.springer.com/). This book follows on The Abel Prize: 2003-2007. The First Five Years (Springer, 2010) and The Abel Prize 2008-2012 (Springer 2014), which profile the work of the previous Abel Prize winners.
Publisher: Springer
ISBN: 3319990284
Category : Mathematics
Languages : en
Pages : 762
Book Description
The book presents the winners of the Abel Prize in mathematics for the period 2013–17: Pierre Deligne (2013); Yakov G. Sinai (2014); John Nash Jr. and Louis Nirenberg (2015); Sir Andrew Wiles (2016); and Yves Meyer (2017). The profiles feature autobiographical information as well as a scholarly description of each mathematician’s work. In addition, each profile contains a Curriculum Vitae, a complete bibliography, and the full citation from the prize committee. The book also includes photos for the period 2003–2017 showing many of the additional activities connected with the Abel Prize. As an added feature, video interviews with the Laureates as well as videos from the prize ceremony are provided at an accompanying website (http://extras.springer.com/). This book follows on The Abel Prize: 2003-2007. The First Five Years (Springer, 2010) and The Abel Prize 2008-2012 (Springer 2014), which profile the work of the previous Abel Prize winners.
Reverse Engineering of Rubber Products
Author: Saikat Das Gupta
Publisher: CRC Press
ISBN: 0849373166
Category : Technology & Engineering
Languages : en
Pages : 360
Book Description
Reverse engineering is widely practiced in the rubber industry. Companies routinely analyze competitors’ products to gather information about specifications or compositions. In a competitive market, introducing new products with better features and at a faster pace is critical for any manufacturer. Reverse Engineering of Rubber Products: Concepts, Tools, and Techniques explains the principles and science behind rubber formulation development by reverse engineering methods. The book describes the tools and analytical techniques used to discover which materials and processes were used to produce a particular vulcanized rubber compound from a combination of raw rubber, chemicals, and pigments. A Compendium of Chemical, Analytical, and Physical Test Methods Organized into five chapters, the book first reviews the construction of compounding ingredients and formulations, from elastomers, fillers, and protective agents to vulcanizing chemicals and processing aids. It then discusses chemical and analytical methods, including infrared spectroscopy, thermal analysis, chromatography, and microscopy. It also examines physical test methods for visco-elastic behavior, heat aging, hardness, and other features. A chapter presents important reverse engineering concepts. In addition, the book includes a wide variety of case studies of formula reconstruction, covering large products such as tires and belts as well as smaller products like seals and hoses. Get Practical Insights on Reverse Engineering from the Book’s Case Studies Combining scientific principles and practical advice, this book brings together helpful insights on reverse engineering in the rubber industry. It is an invaluable reference for scientists, engineers, and researchers who want to produce comparative benchmark information, discover formulations used throughout the industry, improve product performance, and shorten the product development cycle.
Publisher: CRC Press
ISBN: 0849373166
Category : Technology & Engineering
Languages : en
Pages : 360
Book Description
Reverse engineering is widely practiced in the rubber industry. Companies routinely analyze competitors’ products to gather information about specifications or compositions. In a competitive market, introducing new products with better features and at a faster pace is critical for any manufacturer. Reverse Engineering of Rubber Products: Concepts, Tools, and Techniques explains the principles and science behind rubber formulation development by reverse engineering methods. The book describes the tools and analytical techniques used to discover which materials and processes were used to produce a particular vulcanized rubber compound from a combination of raw rubber, chemicals, and pigments. A Compendium of Chemical, Analytical, and Physical Test Methods Organized into five chapters, the book first reviews the construction of compounding ingredients and formulations, from elastomers, fillers, and protective agents to vulcanizing chemicals and processing aids. It then discusses chemical and analytical methods, including infrared spectroscopy, thermal analysis, chromatography, and microscopy. It also examines physical test methods for visco-elastic behavior, heat aging, hardness, and other features. A chapter presents important reverse engineering concepts. In addition, the book includes a wide variety of case studies of formula reconstruction, covering large products such as tires and belts as well as smaller products like seals and hoses. Get Practical Insights on Reverse Engineering from the Book’s Case Studies Combining scientific principles and practical advice, this book brings together helpful insights on reverse engineering in the rubber industry. It is an invaluable reference for scientists, engineers, and researchers who want to produce comparative benchmark information, discover formulations used throughout the industry, improve product performance, and shorten the product development cycle.
Carotenoids
Author: John T. Landrum
Publisher: CRC Press
ISBN: 1420052314
Category : Medical
Languages : en
Pages : 562
Book Description
Carotenoids are of great interest due to their essential biological functions in both plants and animals. However, the properties and functions of carotenoids in natural systems are surprisingly complex. With an emphasis on the chemical aspects of these compounds, Carotenoids: Physical, Chemical, and Biological Functions and Properties presents a b
Publisher: CRC Press
ISBN: 1420052314
Category : Medical
Languages : en
Pages : 562
Book Description
Carotenoids are of great interest due to their essential biological functions in both plants and animals. However, the properties and functions of carotenoids in natural systems are surprisingly complex. With an emphasis on the chemical aspects of these compounds, Carotenoids: Physical, Chemical, and Biological Functions and Properties presents a b
Inclusions in Prokaryotes
Author: Jessup M. Shively
Publisher: Springer Science & Business Media
ISBN: 3540337741
Category : Science
Languages : en
Pages : 353
Book Description
The new series "Microbiology Monographs" begins with two volumes on intracellular components in prokaryotes. In this first volume, "Inclusions in Prokaryotes", the components, labeled inclusions, are defined as discrete bodies resulting from synthesis of a metabolic product. Research on the biosynthesis and reutilization of the accumulated materials is still in progress, and interest in the inclusions is growing. This comprehensive volume provides historical background and comprehensive reviews of eight well-known prokaryotic inclusions.
Publisher: Springer Science & Business Media
ISBN: 3540337741
Category : Science
Languages : en
Pages : 353
Book Description
The new series "Microbiology Monographs" begins with two volumes on intracellular components in prokaryotes. In this first volume, "Inclusions in Prokaryotes", the components, labeled inclusions, are defined as discrete bodies resulting from synthesis of a metabolic product. Research on the biosynthesis and reutilization of the accumulated materials is still in progress, and interest in the inclusions is growing. This comprehensive volume provides historical background and comprehensive reviews of eight well-known prokaryotic inclusions.
Active Nitrogen
Author: A. Nelson Wright
Publisher: Academic Press
ISBN: 1483194868
Category : Science
Languages : en
Pages : 615
Book Description
Physical Chemistry, A Series of Monographs: Active Nitrogen presents the methods by which active nitrogen may be produced. This book is composed of five chapters that evaluate the energy content, molecular spectrum, and the emission of active nitrogen. Some of the topics covered in the book are the summary of light-emitting systems of active nitrogen; analysis of Long-Lived Lewis-Rayleigh Afterglow theory and Ionic theory of Mitra; reactions followed by induced light emission; and characteristics of homogeneous recombination. Other chapters deal with the analysis of metastable molecule theories and the mechanisms for reactions of active nitrogen involving direct N(4S) attack. The discussion then shifts to the rate constants for reactions induced by direct N(4S) attack. The evaluation of the Short-Lived Energetic Afterglow theory is presented. The final chapter is devoted to the examination of emission from molecular species with electronic energy levels below 9.76 eV. The book can provide useful information to physicists, students, and researchers.
Publisher: Academic Press
ISBN: 1483194868
Category : Science
Languages : en
Pages : 615
Book Description
Physical Chemistry, A Series of Monographs: Active Nitrogen presents the methods by which active nitrogen may be produced. This book is composed of five chapters that evaluate the energy content, molecular spectrum, and the emission of active nitrogen. Some of the topics covered in the book are the summary of light-emitting systems of active nitrogen; analysis of Long-Lived Lewis-Rayleigh Afterglow theory and Ionic theory of Mitra; reactions followed by induced light emission; and characteristics of homogeneous recombination. Other chapters deal with the analysis of metastable molecule theories and the mechanisms for reactions of active nitrogen involving direct N(4S) attack. The discussion then shifts to the rate constants for reactions induced by direct N(4S) attack. The evaluation of the Short-Lived Energetic Afterglow theory is presented. The final chapter is devoted to the examination of emission from molecular species with electronic energy levels below 9.76 eV. The book can provide useful information to physicists, students, and researchers.
Prokaryotic Cell Wall Compounds
Author: Helmut König
Publisher: Springer Science & Business Media
ISBN: 364205062X
Category : Science
Languages : en
Pages : 518
Book Description
Microbial cell wall structures play a significant role in maintaining cells’ shape, as protecting layers against harmful agents, in cell adhesion and in positive and negative biological activities with host cells. All prokaryotes, whether they are bacteria or archaea, rely on their surface polymers for these multiple functions. Their surfaces serve as the indispensable primary interfaces between the cell and its surroundings, often mediating or catalyzing important interactions. Prokaryotic Cell Wall Compounds summarizes the current state of knowledge on the prokaryotic cell wall. Topics concerning bacterial and archaeal polymeric cell wall structures, biological activities, growth and inhibition, cell wall interactions and the applications of cell wall components, especially in the field of nanobiotechnology, are presented.
Publisher: Springer Science & Business Media
ISBN: 364205062X
Category : Science
Languages : en
Pages : 518
Book Description
Microbial cell wall structures play a significant role in maintaining cells’ shape, as protecting layers against harmful agents, in cell adhesion and in positive and negative biological activities with host cells. All prokaryotes, whether they are bacteria or archaea, rely on their surface polymers for these multiple functions. Their surfaces serve as the indispensable primary interfaces between the cell and its surroundings, often mediating or catalyzing important interactions. Prokaryotic Cell Wall Compounds summarizes the current state of knowledge on the prokaryotic cell wall. Topics concerning bacterial and archaeal polymeric cell wall structures, biological activities, growth and inhibition, cell wall interactions and the applications of cell wall components, especially in the field of nanobiotechnology, are presented.
Phenolics in Food and Nutraceuticals
Author: Fereidoon Shahidi
Publisher: CRC Press
ISBN: 0203508734
Category : Science
Languages : en
Pages : 576
Book Description
Phenolics in Food and Nutraceuticals is the first single-source compendium of essential information concerning food phenolics. This unique book reports the classification and nomenclature of phenolics, their occurrence in food and nutraceuticals, chemistry and applications, and nutritional and health effects. In addition, it describes antioxidant a
Publisher: CRC Press
ISBN: 0203508734
Category : Science
Languages : en
Pages : 576
Book Description
Phenolics in Food and Nutraceuticals is the first single-source compendium of essential information concerning food phenolics. This unique book reports the classification and nomenclature of phenolics, their occurrence in food and nutraceuticals, chemistry and applications, and nutritional and health effects. In addition, it describes antioxidant a
Chemical Thermodynamics of Neptunium and Plutonium
Author: Robert J. Lemire
Publisher: Elsevier
ISBN: 9780444503794
Category : Medical
Languages : en
Pages : 876
Book Description
Unlike earlier books in this series, this review describes the selection of chemical thermodynamic data for species of two elements, neptunium and plutonium. Although this came about more by circumstance than design, it has allowed for a more consistent approach to chemical interpretation than might have occurred in two separate treatments. It has also drawn attention to cases where the available data do not show expected parallels, and where further work may be useful to confirm or refute apparent differences in the behaviour of neptunium and plutonium.
Publisher: Elsevier
ISBN: 9780444503794
Category : Medical
Languages : en
Pages : 876
Book Description
Unlike earlier books in this series, this review describes the selection of chemical thermodynamic data for species of two elements, neptunium and plutonium. Although this came about more by circumstance than design, it has allowed for a more consistent approach to chemical interpretation than might have occurred in two separate treatments. It has also drawn attention to cases where the available data do not show expected parallels, and where further work may be useful to confirm or refute apparent differences in the behaviour of neptunium and plutonium.
Erectile Dysfunction
Author: Udo Jonas
Publisher: Springer Science & Business Media
ISBN: 3662009862
Category : Medical
Languages : en
Pages : 341
Book Description
The basic principles of the phenomenon "erection" have been known since the pioneering work of Kolliker, Eckhard and Langley in the nineteenth century. Nonetheless, under the influence of Freud, erectile dysfunction was predominantly at tributed to psychogenic factors. A more liberal perception of sexuality since the 1960s, the development of new and refined diagnostic techniques, and the expansion of basic research activity resulted in a new concept of erectile dysfunction, identifying arteriogenic, venogenic, endocrinologic or myopathic (cavernous smooth muscle dysfunction) factors. From this research other considerations such as autonomic innervation, cavernous endo thelial intactness or impaired neurotransmitter pool are being introduced into routine clinical assessment. A reevaluation of psychogenic etiology with a consequential new concept of psy chogenic impotence is on the rise. In this book the new concepts of basic knowledge on cavernous smooth muscle function and its supraspinal, spinal, and local control; the new diagnostic approaches in psychogenic and autonomic factors; and the new developments of reconstructive therapeutic options for the patient have been tied together. Outstanding and internationally renowned experts in the field of erectile dysfunction have given detailed insight into the latest basic and clinical developments. Well-established diagnostic and thera peutic techniques are presented by experienced colleagues. We hope that this book will help the reader to get an overview of the current concepts of erection. Furthermore, we hope that international collaboration in basic and clinical research in the field of erectile dysfunction will render an update necessary in the near future.
Publisher: Springer Science & Business Media
ISBN: 3662009862
Category : Medical
Languages : en
Pages : 341
Book Description
The basic principles of the phenomenon "erection" have been known since the pioneering work of Kolliker, Eckhard and Langley in the nineteenth century. Nonetheless, under the influence of Freud, erectile dysfunction was predominantly at tributed to psychogenic factors. A more liberal perception of sexuality since the 1960s, the development of new and refined diagnostic techniques, and the expansion of basic research activity resulted in a new concept of erectile dysfunction, identifying arteriogenic, venogenic, endocrinologic or myopathic (cavernous smooth muscle dysfunction) factors. From this research other considerations such as autonomic innervation, cavernous endo thelial intactness or impaired neurotransmitter pool are being introduced into routine clinical assessment. A reevaluation of psychogenic etiology with a consequential new concept of psy chogenic impotence is on the rise. In this book the new concepts of basic knowledge on cavernous smooth muscle function and its supraspinal, spinal, and local control; the new diagnostic approaches in psychogenic and autonomic factors; and the new developments of reconstructive therapeutic options for the patient have been tied together. Outstanding and internationally renowned experts in the field of erectile dysfunction have given detailed insight into the latest basic and clinical developments. Well-established diagnostic and thera peutic techniques are presented by experienced colleagues. We hope that this book will help the reader to get an overview of the current concepts of erection. Furthermore, we hope that international collaboration in basic and clinical research in the field of erectile dysfunction will render an update necessary in the near future.