High-energy Collision-induced Dissociation of Macromolecules Using Tandem Double-focusing/time-of-flight Mass Spectrometry PDF Download
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Author: Andrew R. Bottrill
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Author: Andrew R. Bottrill
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Author: Andrew R. Bottrill
Publisher:
ISBN:
Category : Atoms
Languages : en
Pages :
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Author: Douglas John Beussman
Publisher:
ISBN:
Category : Chromatographic analysis
Languages : en
Pages : 554
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Author:
Publisher:
ISBN:
Category : Biomedical engineering
Languages : en
Pages : 130
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Book Description
Author: Barry Leonard
Publisher: DIANE Publishing
ISBN: 0788141872
Category : Biomedical engineering
Languages : en
Pages : 93
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Book Description
Promotes access to a network of biomedical technology resource centers throughout the nation. These centers make state-of-the-art technologies & methods available to thousands of biomedical investigators each year. The directory is organized into scientific areas: biomedical computing, biochemical materials, biomedical engineering, non-invasive imaging & spectroscopy, & cellular & molecular structure & function. Each entry includes the principal investigator & control person, the research being conducted, & capabilities of the resource that are available to outside investigators.
Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 312
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Book Description
Theses on any subject submitted by the academic libraries in the UK and Ireland.
Author: Carissa Ann Stark
Publisher:
ISBN:
Category : Chemistry, Forensic
Languages : en
Pages : 342
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Book Description
Author: Emmanuel N. Raptakis
Publisher:
ISBN:
Category : Biomolecules
Languages : en
Pages : 532
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Book Description
Author: Stavros Kromidas
Publisher: John Wiley & Sons
ISBN: 3527809171
Category : Science
Languages : en
Pages : 255
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Book Description
Dieses prägnante, kompakte und übersichtliche Fachbuch befasst sich ausschließlich mit den praktischen Aspekten der HPLC-MS-Kopplung und vermittelt detailliert die Kenntnisse, um diese Methode effizient einsetzen zu können. Nach einem Überblick über den aktuellen Wissensstand rund um HPLC-MS und die eingesetzten Instrumente werden alle relevanten Aspekte der Methodenentwicklung erläutert. Ein Kapitel zeigt Tipps und Tricks und enthält Anwenderberichte zu den Vorteilen und Tücken bei der Anwendung der Methode in der Praxis. Abgerundet werden die Darstellungen durch einen Ausblick auf zukünftige Entwicklungen renommierter Hersteller.
Author: Jonathan Robert Beck
Publisher:
ISBN:
Category : Chemical kinetics
Languages : en
Pages : 218
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Book Description
Analysis of large molecules from proteins to peptides and even higher mass species such as DNA is an important task, and in recent years, has been a specialty of mass spectrometry. Gaining structural information is possible using multi stage mass spectrometric techniques (MS) n . The technique of surface induced dissociation (SID) of singly protonated peptides ionized by matrix assisted laser desorption/ionization and analyzed by a tandem time-of-flight mass spectrometer with a collision surface located between the two time-of-flight mass spectrometers is described here. The identity of positively charged product ions from SID is dependent on the velocity of the parent ions colliding at near normal angles to the SID surface. This dependence on collision velocity is evident for the entire mass range of peptides studied (280-12,384 amu). The observed trend suggests that SID has the potential to fragment very large ions, yielding product ions of certain identities, as long as, the necessary collision energy/velocity can be achieved. SID of the protonated peptides produces product ions that fall into categories of the following types of product ions: intact molecular ions, backbone fragments, single amino acid immonium ions (H 2 N = CH-R) +, immonium ion fragments, and finally, sputtered surface material. The range of collision energies over which these products occurs changes based upon the mass of the ion, but is constant for collision velocity. The ranges of collision velocities for the different types of product ions are as follows: intact molecular ions and backbone fragments (3500 m/s), single amino acid immonium ions (2600-5000 m/s), fragments of immonium ions (5000-13,000 m/s), and sputtered ions from the surface (13,200 m/s).
