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Author: Nicholas Mrosovsky
Publisher: Springer Science & Business Media
ISBN: 1468471767
Category : Science
Languages : en
Pages : 296
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Book Description
Mammalian hibernation is commonly thought of as something completely out of the ordinary, a "unique and unorthodox state." The present book takes the opposite view. It argues that the physiological achievements of hibernators do not deEend on special mechanisms but on special use of ordinary mechanisms. It is precisely this that makes the hibernators important. If the hibernators de pend on some unique physiological principle their study is that of a biological curio. But if they are using basic mammalian systems in a quantitatively extreme way, then they are a naturally occurring preparation of enormous potential. Hibernation involves every aspect of the animal's biology from fat metabo lism to behavior, from thermoregulation to dental caries; every system in the body is affected in some way or other by hibernation. A comprehensive account of hibernation would be almost coextensive with an account of the whole of mammalian biology. The present book does not attempt to describe everything that has been discovered about hibernation. Excellent coverage for that already exists in the proceedings of three recent symposia and in the other major source materials listed on page 233. There is in fact an enormous amount of information already available. But there is a difference between information and understanding. Despite the increasing volume of research and growing interest in mammalian hibernation, there is little appreciation of the essential characteristics of the phenomena. The pieces of the puzzle lie scattered.
Author: Nicholas Mrosovsky
Publisher: Springer Science & Business Media
ISBN: 1468471767
Category : Science
Languages : en
Pages : 296
Get Book Here
Book Description
Mammalian hibernation is commonly thought of as something completely out of the ordinary, a "unique and unorthodox state." The present book takes the opposite view. It argues that the physiological achievements of hibernators do not deEend on special mechanisms but on special use of ordinary mechanisms. It is precisely this that makes the hibernators important. If the hibernators de pend on some unique physiological principle their study is that of a biological curio. But if they are using basic mammalian systems in a quantitatively extreme way, then they are a naturally occurring preparation of enormous potential. Hibernation involves every aspect of the animal's biology from fat metabo lism to behavior, from thermoregulation to dental caries; every system in the body is affected in some way or other by hibernation. A comprehensive account of hibernation would be almost coextensive with an account of the whole of mammalian biology. The present book does not attempt to describe everything that has been discovered about hibernation. Excellent coverage for that already exists in the proceedings of three recent symposia and in the other major source materials listed on page 233. There is in fact an enormous amount of information already available. But there is a difference between information and understanding. Despite the increasing volume of research and growing interest in mammalian hibernation, there is little appreciation of the essential characteristics of the phenomena. The pieces of the puzzle lie scattered.
Author: Mike Ludwig
Publisher: John Wiley & Sons
ISBN: 1119390885
Category : Medical
Languages : en
Pages : 462
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Book Description
Model Animals in Neuroendocrinology: From Worm to Mouse to Man offers a masterclass on the opportunities that different model animals offer to the basic understanding of neuroendocrine functions and mechanisms of action and the implications of this understanding. The authors review recent advances in the field emanating from studies involving a variety of animal models, molecular genetics, imaging technologies, and behavior assays. These studies helped unravel mechanisms underlying the development and function of neuroendocrine systems. The book highlights how studies in a variety of model animals, including, invertebrates, fish, birds, rodents and mammals has contributed to our understanding of neuroendocrinology. Model Animals in Neuroendocrinology provides students, scientists and practitioners with a contemporary account of what can be learnt about the functions of neuroendocrine systems from studies across animal taxonomy. This is the seventh volume in the Masterclass in Neuroendocrinology Series, a co-publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.
Author: N. Hayashi
Publisher: Springer Science & Business Media
ISBN: 4431668829
Category : Medical
Languages : en
Pages : 253
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Book Description
Rapid progress in technology and its application to diagnosis and monitoring of brain tissue temperature and metabolism have resulted in advances in the therapy for critically brain-injured patients and breakthroughs in understanding the pathophysiology of brain damage. The latest concept of brain hypothermia therapy clarifies targets such as brain thermal pooling, masking brain hypoxia associated with catecholamine surge, the metabolic shift from glucose to lipids, and selective radical damage of dopamine in the central nervous system. This volume explains the mechanism of brain injury and how brain hypothermia treatment differs from other hypothermia therapy in four major sections: Brain Injury Mechanism, Pathophysiology of Hypothermia, Basic Research of Hypothermia Treatment, and Clinical Studies of Brain Hypothermia. The book is a valuable source for practitioners and researchers in neurosurgery and neurology and in critical care and emergency medicine.
Author: Charles P Lyman
Publisher: Elsevier
ISBN: 0323138241
Category : Nature
Languages : en
Pages : 332
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Book Description
Hibernation and Torpor in Mammals and Birds explores the physiological factors that control hibernation and torpor in birds and mammals. This text covers topics ranging from metabolism in hibernation to the role of endocrines, respiration and acid-base state in hibernation, and theories of hibernation. This book is comprised of 14 chapters and begins with an overview of some clear-cut definitions and why mammals and birds hibernate. The reader is then introduced to the variations from euthermia that have been observed among birds and mammals. To give some structure to this listing, the approach is phylogenetic, starting with the birds and proceeding through the primitive to the more advanced mammals. Subsequent chapters explains the process of entering hibernation and the hibernating state, itself; capability of a species in natural hibernation to arouse from that state using self-generated heat; physiological changes at the start of a spontaneous arousal; and physiological mechanisms underlying the ability of hibernators to rewarm. Consideration is also given to intermediary metabolism in hibernation, cold adaptation of metabolism in hibernators, and the response of hibernators to various extrinsic influences such as neoplastic growth, radiation injury, and parasitism and symbionts. This book will be of interest to students and researchers in fields ranging from zoology to physiology and biophysics.
Author: Gerhard Heldmaier
Publisher: Springer Science & Business Media
ISBN: 9783540674108
Category : Medical
Languages : en
Pages : 568
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Book Description
This book gives an up-to-date account of the current knowledge of cold adaptation in animals, including phenomena like hibernation, daily torpor, thermoregulation and thermogenesis, metabolic regulation, freeze tolerance, anaerobiosis, metabolic depression and related processes. For the next four years - until the 12th International Hibernation Symposium - it will serve as a state-of-the-art reference source for every scientist and graduate student working in these areas of physiology and zoology.
Author: John W. Winkelman
Publisher: Cambridge University Press
ISBN: 1139494341
Category : Medical
Languages : en
Pages : 435
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Book Description
Sleep-related complaints are extremely common across the spectrum of psychiatric illness. Accurate diagnosis and management of sleep disturbances requires an understanding of the neurobiological mechanisms underlying sleep and wakefulness, the characteristics of sleep disturbance inherent to psychiatric illness and primary sleep disorders, as well as the psychopharmacologic and behavioral treatments available. Foundations of Psychiatric Sleep Medicine provides a uniquely accessible, practical, and expert summary of current clinical concepts at the sleep-psychiatry interface. Topics covered include: basic principles in sleep science, clinical sleep history taking, primary sleep disorders in psychiatric contexts, and sleep disturbance across a range of mood, anxiety, psychotic, substance use, cognitive and developmental disorders. Written by outstanding experts in the field of sleep medicine and psychiatry, this academically rigorous and clinically useful text is an essential resource for psychiatrists, psychologists and other health professionals interested in the relationship between sleep and mental illness.
Author: John K. Young
Publisher:
ISBN: 9786613836458
Category : Brain
Languages : en
Pages : 161
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Book Description
In this fascinating tour of the way our brains control our most basic drives, John Young takes a small part of the human anatomy and explains its role in the regulation of our basic needs and desires, including sex, sleep, thirst, hunger and more. Drawing on the latest research, he conveys even complex ideas in accessible and enjoyable fashion.
Author: M.A. Steiner
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318068446
Category : Health & Fitness
Languages : en
Pages : 165
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Book Description
The orexin system, discovered in 1998, has emerged as a crucial player in regulating the sleep and wake balance inside our brain. This discovery has sparked a burst of novel and dynamic research on the physiology and pathology of sleep. The Orexin System: Basic Science and Role in Sleep Pathology honors this research and the authors share their ideas and perspectives on the novel developments within the field. The book examines the intricate role of the orexin system in regulating sleep and wake, and its interaction with other wake-regulating systems. The orexin system is dissected at the cellular and molecular level to explore the diversity of the orexin-producing neurons, their projections, and their signaling pathways. Additionally, the book discusses the diseases which are associated with a dysfunctional orexin system, such as narcolepsy, insomnia, substance abuse, and Alzheimer’s disease, and explores the new potential therapeutic applications derived from the burst of research around this fascinating system. This publication is essential reading for neurobiologists, neurologists, psychopharmacologists, sleep researchers, and other researchers and clinical scientists interested in sleep, sleep research, insomnia, and medicine in general.
Author: György Buzsáki
Publisher: Springer
ISBN: 3319288024
Category : Medical
Languages : en
Pages : 181
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Book Description
This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments. The individual chapters cover several fascinating facets of contemporary neuroscience from elementary computation of neurons, mesoscopic network oscillations, internally generated assembly sequences in the service of cognition, large-scale neuronal interactions within and across systems, the impact of sleep on cognition, memory, motor-sensory integration, spatial navigation, large-scale computation and consciousness. Each of these topics require appropriate levels of analyses with sufficiently high temporal and spatial resolution of neuronal activity in both local and global networks, supplemented by models and theories to explain how different levels of brain dynamics interact with each other and how the failure of such interactions results in neurologic and mental disease. While such complex questions cannot be answered exhaustively by a dozen or so chapters, this volume offers a nice synthesis of current thinking and work-in-progress on micro-, meso- and macro- dynamics of the brain.
Author: G. Buzsáki
Publisher: Oxford University Press
ISBN: 0199828237
Category : Medical
Languages : en
Pages : 465
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Book Description
Studies of mechanisms in the brain that allow complicated things to happen in a coordinated fashion have produced some of the most spectacular discoveries in neuroscience. This book provides eloquent support for the idea that spontaneous neuron activity, far from being mere noise, is actually the source of our cognitive abilities. It takes a fresh look at the coevolution of structure and function in the mammalian brain, illustrating how self-emerged oscillatory timing is the brain's fundamental organizer of neuronal information. The small-world-like connectivity of the cerebral cortex allows for global computation on multiple spatial and temporal scales. The perpetual interactions among the multiple network oscillators keep cortical systems in a highly sensitive "metastable" state and provide energy-efficient synchronizing mechanisms via weak links. In a sequence of "cycles," György Buzsáki guides the reader from the physics of oscillations through neuronal assembly organization to complex cognitive processing and memory storage. His clear, fluid writing-accessible to any reader with some scientific knowledge-is supplemented by extensive footnotes and references that make it just as gratifying and instructive a read for the specialist. The coherent view of a single author who has been at the forefront of research in this exciting field, this volume is essential reading for anyone interested in our rapidly evolving understanding of the brain.
