Hereditary Effects of Radiation

Hereditary Effects of Radiation PDF Author: United Nations. Scientific Committee on the Effects of Atomic Radiation
Publisher: The Committee
ISBN:
Category : Medical
Languages : en
Pages : 166

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Book Description
The 2001 report completed a comprehensive review of the risks to offspring following parental exposure to radiation. The review included an evaluation of those diseases which have both hereditary and environmental components. The major finding is that the total hereditary risk to the first generation following radiation is less than one tenth of the risk of fatal carcinogenesis following irrradiation. The Committee concluded that a sounder basis now exists for estimating the hereditary risks of radiation exposure. This is due to advances in molecular genetics, and in the evaluation of multifactorial diseases, such as coronary heart disease.

Health Risks from Exposure to Low Levels of Ionizing Radiation

Health Risks from Exposure to Low Levels of Ionizing Radiation PDF Author: Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation
Publisher: National Academies Press
ISBN: 0309133343
Category : Science
Languages : en
Pages : 422

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Book Description
This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.

Health Effects of Exposure to Low Levels of Ionizing Radiation

Health Effects of Exposure to Low Levels of Ionizing Radiation PDF Author: National Research Council
Publisher: National Academies
ISBN: 0309039959
Category : Science
Languages : en
Pages : 436

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Book Description
This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.

The Children of Atomic Bomb Survivors

The Children of Atomic Bomb Survivors PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309045371
Category : Science
Languages : en
Pages : 524

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Book Description
Do persons exposed to radiation suffer genetic effects that threaten their yet-to-be-born children? Researchers are concluding that the genetic risks of radiation are less than previously thought. This finding is explored in this volume about the children of atomic bomb survivors in Hiroshima and Nagasakiâ€"the population that can provide the greatest insight into this critical issue. Assembled here for the first time are papers representing more than 40 years of research. These documents reveal key results related to radiation's effects on pregnancy termination, sex ratio, congenital defects, and early mortality of children. Edited by two of the principal architects of the studies, J. V. Neel and W. J. Schull, the volume also offers an important comparison with studies of the genetic effects of radiation on mice. The wealth of technical details will be immediately useful to geneticists and other specialists. Policymakers will be interested in the overall conclusions and discussion of future studies.

Practical Radiation Protection in Healthcare

Practical Radiation Protection in Healthcare PDF Author: Colin J. Martin
Publisher: Oxford University Press, USA
ISBN: 0199655219
Category : Medical
Languages : en
Pages : 551

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Book Description
Written by practitioners experienced in the field, 'Practical Radiation Protection in Healthcare' provides a practical guide for medical physicists and others involved with radiation protection in the healthcare environment.

Effects of Atomic Radiation

Effects of Atomic Radiation PDF Author: William J. Schull
Publisher: Wiley-Liss
ISBN: 9780471125242
Category : Medical
Languages : en
Pages : 430

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Book Description
Presenting a monumental achievement: 50 years of data cataloging the immediate, long-term, and hereditary effects of atomic radiation on the survivors of the Hiroshima and Nagasaki bombs. Authored by one of the key members of the Atomic Bomb Casualty Commission founded in 1947, this unique work documents the critical findings and conclusions of the longest ongoing medical study in history; it will surely become the foundation for all future investigations and standards regarding the bioeffects of ionizing radiation. "In my opinion, Dr. Schull has written a very interesting and accurate account of the atomic bomb follow-up program in Japan. He writes extremely well, with areas of his particular scientific interest described in great detail. He also describes events and the social implications in a manner that has broad, general appeal." —Stuart C. Finch, MD University of Medicine and Dentistry of New Jersey "A history of the Hiroshima/Nagasaki study is badly needed. I was very happy to hear that Jack Schull was working on such a project, and it is an understatement to say that I am anxious to see it published." —Seymour Jablon, PhD Bethesda, Maryland "Rarely in the history of a program will one have a nearly 50-year account from an eyewitness and major participant, beginning with the program's onset to the present. Jack's book offers the reader this extraordinary insight into the birth and development of the study of the A-bomb survivors. Moreover, he has served on all major national and international commissions dealing with radiation protection and risk assessment and he interweaves the Japanese studies into the radiation risk issues in a way that few, if any, other contemporary scientists can." —Seymour Abrahamson, PhD Radiation Effects Research Foundation On August 6 and 9, 1945, the only atomic bombs ever used in warfare were dropped on the Japanese cities of Hiroshima and Nagasaki. The destruction and death caused by those bombings presented the world with a vivid portrait of the dangers of the atomic age. However, the thousands of bomb survivors have given scientists a massive, firsthand perspective on the bioeffects of radioactivity. It is the study of these survivors that forms the foundation of the modern understanding of the immediate, long-term, and hereditary consequences of exposure to ionizing radiation. Effects of Atomic Radiation: A Half-Century of Studies from Hiroshima and Nagasaki is the definitive account of the methods, findings, and conclusions of the 50-year study on the survivors of the atomic bomb blasts. It is a truly monumental work, surveying a colossal body of data to offer a comprehensive, unified, and authoritative summary of not only the scientific study itself, but the personal, social, and political factors that have shaped the investigation from its inception. The book goes beyond the simple compilation of facts, giving the reader unique insight into this unprecedented research project and exploring the complex web of subjective perceptions and fears that color popular, national, and even scientific views of radiation exposure in moderate and extreme cases. Authored by Dr. William J. Schull, perhaps the single most influential scientist involved in the studies, this book conveys both his authority and sensitivity. Dr. Schull arrived in Japan in 1949 and was instrumental in the development of the Atomic Bomb Casualty Commission. Since then, he has been one of the driving forces behind the largest medical follow-up study ever undertaken. His years spent working directly with bomb survivors imbue his narrative with a compelling personal history, and his service on numerous national and international committees studying ionizing radiation give him a broad, authoritative perspective on the implications of the ABCC's work. Effects of Atomic Radiation: A Half-Century of Studies from Hiroshima and Nagasaki is first and foremost a scientific work, summarizing the core findings of the definitive study on radiation exposure; while throughout the book, the author provides personal accounts that illustrate the human dimensions of the bombings. In a world where nuclear power is increasing and exposure to radiation is a daily occurrence, this book is essential reading for all scientists associated with public, private, or governmental institutions that set standards of acceptability for exposure.

Health Risks of Radon and Other Internally Deposited Alpha-Emitters

Health Risks of Radon and Other Internally Deposited Alpha-Emitters PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309037891
Category : Science
Languages : en
Pages : 623

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Book Description
This book describes hazards from radon progeny and other alpha-emitters that humans may inhale or ingest from their environment. In their analysis, the authors summarize in one document clinical and epidemiological evidence, the results of animal studies, research on alpha-particle damage at the cellular level, metabolic pathways for internal alpha-emitters, dosimetry and microdosimetry of radionuclides deposited in specific tissues, and the chemical toxicity of some low-specific-activity alpha-emitters. Techniques for estimating the risks to humans posed by radon and other internally deposited alpha-emitters are offered, along with a discussion of formulas, models, methods, and the level of uncertainty inherent in the risk estimates.

Radiobiology for the Radiologist

Radiobiology for the Radiologist PDF Author: Eric J. Hall
Publisher: Lippincott Williams & Wilkins
ISBN: 1451154186
Category : Medical
Languages : en
Pages : 908

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Book Description
In print since 1972, this seventh edition of Radiobiology for the Radiologist is the most extensively revised to date. It consists of two sections, one for those studying or practicing diagnostic radiolo, nuclear medicine and radiation oncology; the other for those engaged in the study or clinical practice of radiation oncology--a new chapter, on radiologic terrorism, is specifically for those in the radiation sciences who would manage exposed individuals in the event of a terrorist event. The 17 chapters in Section I represent a general introduction to radiation biology and a complete, self-contained course especially for residents in diagnostic radiology and nuclear medicine that follows the Syllabus in Radiation Biology of the RSNA. The 11 chapters in Section II address more in-depth topics in radiation oncology, such as cancer biology, retreatment after radiotherapy, chemotherapeutic agents and hyperthermia. Now in full color, this lavishly illustrated new edition is replete with tables and figures that underscore essential concepts. Each chapter concludes with a "summary of pertinent conclusions" to facilitate quick review and help readers retain important information.

The Genetics of Cancer

The Genetics of Cancer PDF Author: B.A. Ponder
Publisher: Springer Science & Business Media
ISBN: 9401106770
Category : Medical
Languages : en
Pages : 222

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Book Description
It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.

Low-Dose Radiation Effects on Animals and Ecosystems

Low-Dose Radiation Effects on Animals and Ecosystems PDF Author: Manabu Fukumoto
Publisher: Springer Nature
ISBN: 9811382182
Category : Science
Languages : en
Pages : 259

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Book Description
This open access book summarizes the latest scientific findings regarding the biological effects of the Fukushima Daiichi Nuclear Power Plant (FNPP) accident in 2011. Various cases of changes in animals and organisms have been reported since the FNPP accident. However, it is often unknown whether they are actually due to radiation, since the dose or dose-rate are not necessarily associated with the changes observed. This book brings together the works of radiation biologists and ecologists to provide reliable radioecology data and gives insight into future radioprotection. The book examines the environmental pollution and radiation exposure, and contains valuable data from abandoned livestock in the ex-evacuation zone and from wild animals including invertebrates and vertebrates, aqueous and terrestrial animals, and plants that are subjected to long-term exposure in the area still affected by radiation. It also analyzes dose evaluation, and offers new perspectives gained from the accident, as well as an overview for future studies to promote radioprotection of humans and the ecosystem. Since the biological impact of radiation is influenced by various factors, it is difficult to scientifically define the effects of low-dose/low-dose-rate radiation. However, the detailed research data presented can be combined with the latest scientific and technological advances, such as artificial intelligence, to provide new insights in the future. This book is a unique and valuable resource for researchers, professionals and anyone interested in the impact of exposure to radiation or contamination with radioactive materials.