Handbook of Hemorheology and Hemodynamics PDF Download
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Author: O.K. Baskurt
Publisher: IOS Press
ISBN: 1607502631
Category : Medical
Languages : en
Pages : 468
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Book Description
This publication primarily focuses on the macro- and micro-rheological behavior of blood and its formed elements, on interactions between the formed elements and blood vessel walls, and on the microvascular aspects of hemodynamics. Since many aspects of hemorheology and hemodynamics are affected by disease or clinical states, these effects are discussed as are hyperviscosity syndromes, therapy for disturbed blood rheology, and methods in hemorheology and hemodynamics. Sections of the Handbook include History of Hemorheology; Hemorheology, covering basic aspects, blood composition, blood rheology, cell mechanics, pathophysiology, methods and comparative studies; Hemodynamics, covering basic principles, microcirculation, in vivo effects, endothelium and methods; and Clinical Aspects of Hemorheology, covering hyperviscosity, clinical significance and treatment. The goal is to foster greater interchange between workers in the fields so as to promote collaborative efforts and, hopefully, improved health. In selecting topics for this handbook the editors have attempted to provide a general overview of both basic science and clinical hemorheology and hemodynamics. Hemorheology and hemodynamics are closely related, the former dealing with all aspects of the flow and interactions of the individual blood cells mostly studied in vitro, the latter with the in vivo relationships among vessel architecture, driving pressure, flow rate and shear stress. The linkage between the in vitro and in vivo research described in the book will be of interest to both basic science and clinical investigators. The editors of the handbook have each been active in the fields of bio- and hemorheology for many years, and have published extensively. They have successfully achieved their objective to publish a well-written and well-edited handbook that will be valuable for researchers and students in the field.
Author: O.K. Baskurt
Publisher: IOS Press
ISBN: 1607502631
Category : Medical
Languages : en
Pages : 468
Get Book Here
Book Description
This publication primarily focuses on the macro- and micro-rheological behavior of blood and its formed elements, on interactions between the formed elements and blood vessel walls, and on the microvascular aspects of hemodynamics. Since many aspects of hemorheology and hemodynamics are affected by disease or clinical states, these effects are discussed as are hyperviscosity syndromes, therapy for disturbed blood rheology, and methods in hemorheology and hemodynamics. Sections of the Handbook include History of Hemorheology; Hemorheology, covering basic aspects, blood composition, blood rheology, cell mechanics, pathophysiology, methods and comparative studies; Hemodynamics, covering basic principles, microcirculation, in vivo effects, endothelium and methods; and Clinical Aspects of Hemorheology, covering hyperviscosity, clinical significance and treatment. The goal is to foster greater interchange between workers in the fields so as to promote collaborative efforts and, hopefully, improved health. In selecting topics for this handbook the editors have attempted to provide a general overview of both basic science and clinical hemorheology and hemodynamics. Hemorheology and hemodynamics are closely related, the former dealing with all aspects of the flow and interactions of the individual blood cells mostly studied in vitro, the latter with the in vivo relationships among vessel architecture, driving pressure, flow rate and shear stress. The linkage between the in vitro and in vivo research described in the book will be of interest to both basic science and clinical investigators. The editors of the handbook have each been active in the fields of bio- and hemorheology for many years, and have published extensively. They have successfully achieved their objective to publish a well-written and well-edited handbook that will be valuable for researchers and students in the field.
Author: Antonio Fasano
Publisher: Springer
ISBN: 3319605135
Category : Mathematics
Languages : en
Pages : 352
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Book Description
This book illustrates applications of mathematics to various processes (physiological or artificial) involving flowing blood, including hemorheology, microcirculation, coagulation, kidney filtration and dialysis, offering a historical overview of each topic. Mathematical models are used to simulate processes normally occurring in flowing blood and to predict the effects of dysfunctions (e.g. bleeding disorders, renal failure), as well as the effects of therapies with an eye to improving treatments. Most of the models have a completely new approach that makes patient-specific simulations possible. The book is mainly intended for mathematicians interested in medical applications, but it is also useful for clinicians such as hematologists, nephrologists, cardio-surgeons, and bioengineers. Some parts require no specific knowledge of mathematics. The book is a valuable addition to mathematics, medical, biology, and bioengineering libraries.
Author: Giles R. Cokelet
Publisher: Morgan & Claypool Publishers
ISBN: 1615041621
Category : Medical
Languages : en
Pages : 143
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Book Description
From the perspective of blood flow, blood has some unusual properties: it is a suspension of blood cells of which the red blood cells are most numerous and are both deformable (at moderate and high flow rates) and will aggregate under conditions of slow flow. Also, the cellular volume concentration is high (about 40-45%). These features cause blood to have variable viscosity, dependent on flow conditions, and cause both red blood cell sedimentation and syneresis effects under slow flow conditions (which can lead to rheological artifacts). These effects also cause unusual flow phenomena when blood flows in systems of small diameter vessels (especially for diameters of about 500 μm or less). These phenomena are seen in non-uniform cell distributions in vessel cross sections, a cell-poor layer of mostly blood plasma at vessels walls, non-proportionate cellular distribution during blood flow through vascular bifurcations, which leads to a very wide distribution of vessel cellular concentrations (from zero to systemic values) in the smaller vessels of the microcirculation, etc. All these phenomena are discussed in this book, as well as the difficulties presented by in vivo microvessels having non-ideal geometries. Table of Contents: Introduction / The Composition of Blood / Viscometers / Constitutive Equations / At Last, Experimental Data! / Some In Vitro Blood Flows / The Fahraeus Effect / The Fahreus-Lindqvist Effect / In Vitro Arterial-Type Bifurcation Experimental Data / In Vivo Experimental Bifurcation Data / Flow in Microvascular Networks / Optimization / Concluding Statement / References
Author: Oguz Baskurt
Publisher: CRC Press
ISBN: 1439841802
Category : Medical
Languages : en
Pages : 326
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Book Description
Red blood cells in humans—and most other mammals—have a tendency to form aggregates with a characteristic face-to-face morphology, similar to a stack of coins. Known as rouleaux, these aggregates are a normally occurring phenomenon and have a major impact on blood rheology. What is the underlying mechanism that produces this pattern? Does this really happen in blood circulation? And do these rouleaux formations have a useful function? The first book to offer a comprehensive review of the subject, Red Blood Cell Aggregation tackles these and other questions related to red blood cell (RBC) aggregates. The book covers basic, clinical, and physiological aspects of this important biophysical phenomenon and integrates these areas with concepts in bioengineering. It brings together state-of-the-art research on the determinants, mechanisms, and measurement and effects of RBC aggregation as well as on variations and comparative aspects. After an introductory overview, the book outlines factors and conditions that affect RBC aggregation. It presents the two hypotheses—the bridging model and the depletion model—that provide potential mechanisms for the adhesive forces that lead to the regular packing of the cells in rouleaux formations. The book also reviews the methods used to quantify RBC aggregation in vitro, focusing on their importance in clinical practice. Chapters discuss the effect of RBC aggregation on the in vitro rheology of blood as well as on tube flow. The book also looks at what happens in the circulation when red blood cells aggregate and examines variations due to physiological and pathophysiological challenges. The concluding chapter explores the formation of red blood cell aggregates in other mammals. Written by leading researchers in the field, this is an invaluable resource for basic science, medical, and clinical researchers; graduate students; and clinicians interested in mammalian red blood cells.
Author: T.V. How
Publisher: Elsevier
ISBN: 0080551564
Category : Science
Languages : en
Pages : 449
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Book Description
This series presents reviews covering all aspects of haemodynamics and haemorheology. Topics covered include the complexities of microcirculation, the rheology of blood and blood vessels, and the mechanics of blood flow in arteries and veins. The contributions aim to reflect the advances being made in experimental techniques and instrumentation for laboratory and clinical measurements and in numerical and mathematical modelling. Emphasis is placed on the scientific and engineering principles involved, but particular attention is also given to the clinical significance of this area of research. Topics covered by this volume include viscoelastic properties of blood and blood analogues; blood flow through narrow tubes; and numerical modelling of blood flow.
Author: Oguz K. Baskurt
Publisher: IOS Press
ISBN: 1586037714
Category : Medical
Languages : en
Pages : 468
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Book Description
This publication primarily focuses on the macro- and micro- rheological behavior of blood and its formed elements, on interactions between the formed elements and blood vessel walls, and on the microvascular aspects of hemodynamics. Since many aspects of hemorheology and hemodynamics are affected by disease or clinical states, these effects are discussed as are hyperviscosity syndromes, therapy for disturbed blood rheology, and methods in hemorheology and hemodynamics. Sections of the Handbook include History of Hemorheology; Hemorheology, covering basic aspects, blood composition, blood rheology, cell mechanics, pathophysiology, methods and comparative studies; Hemodynamics, covering basic principles, microcirculation, in vivo effects, endothelium and methods; and Clinical Aspects of Hemorheology, covering hyperviscosity, clinical significance and treatment. The goal is to foster greater interchange between workers in the fields so as to promote collaborative efforts and, hopefully, improved health. In selecting topics for this handbook the editors have attempted to provide a general overview of both basic science and clinical hemorheology and hemodynamics. Hemorheology and hemodynamics are closely related, the former dealing with all aspects of the flow and interactions of the individual blood cells mostly studied in vitro, the latter with the in vivo relationships among vessel architecture, driving pressure, flow rate and shear stress. The linkage between the in vitro and in vivo research described in the book will be of interest to both basic science and clinical investigators. The editors of the handbook have each been active in the fields of bio- and hemorheology for many years, and have published extensively. They have successfully achieved their objective to publish a well-written and well-edited handbook that will be valuable for researchers and students in the field.
Author: Gregory D. Sloop
Publisher:
ISBN: 9781536109634
Category : Blood
Languages : en
Pages : 0
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Book Description
The impact of blood viscosity on health and disease has been neglected, even though viscosity is a fundamental property of any fluid. It is inversely proportional to flow, so increased blood viscosity predisposes to thrombosis. Blood viscosity is directly related to systemic vascular resistance, and so blood viscosity affects blood pressure. Blood viscosity is inversely proportional to perfusion, and increased viscosity adversely affects the performance of all organs. By viewing them through the perspective of viscosity, this book provides fresh insight into atherosclerotic cardiovascular disease, hypertension, metabolic syndrome, sepsis, hemolytic anemias, anemia of chronic disease, and aging.
Author: Giovanni P. Galdi
Publisher: Springer Science & Business Media
ISBN: 3764378050
Category : Medical
Languages : en
Pages : 512
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Book Description
This book surveys research results on the physical and mathematical modeling, as well as the numerical simulation of complex fluid and structural mechanical processes occurring in the human blood circulation system. Topics treated include continuum mechanical description; choice of suitable liquid and wall models; mathematical analysis of coupled models; numerical methods for flow simulation; parameter identification and model calibration; fluid-solid interaction; mathematical analysis of piping systems; particle transport in channels and pipes; artificial boundary conditions, and many more. The book was developed from lectures presented by the authors at the Oberwolfach Research Institute (MFO), in Oberwolfach-Walke, Germany, November, 2005.
Author: Constantine Pozrikidis
Publisher: CRC Press
ISBN: 1439820066
Category : Mathematics
Languages : en
Pages : 328
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Book Description
Spanning biological, mathematical, computational, and engineering sciences, computational biofluiddynamics addresses a diverse family of problems involving fluid flow inside and around living organisms, organs, tissue, biological cells, and other biological materials. Computational Hydrodynamics of Capsules and Biological Cells provides a comprehen
Author: Markus Hecker
Publisher: Springer Nature
ISBN: 3030631648
Category : Medical
Languages : en
Pages : 362
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Book Description
This volume of the series Cardiac and Vascular Biology presents the most relevant aspects of vascular mechanobiology along with many more facets of this fascinating, timely and clinically highly relevant field. Mechanotransduction, mechanosensing, fluid shear stress, hameodynamics and cell fate, are just a few topics to name. All important aspects of vascular mechanobiology in health and disease are reviewed by some of the top experts in the field. This volume, together with a second title on cardiac mechanobiology featured in this series, will be of high relevance to scientists and clinical researchers in the area of vascular biology, cardiology and biomedical engineering.
