Health Risk Assessment Dermal and Inhalation Exposure and Absorption of Toxicants PDF Download
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Author: Rhoda G.M. Wang
Publisher: CRC Press
ISBN: 1351361740
Category : Medical
Languages : en
Pages : 544
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Book Description
Health Risk Assessment is a comprehensive reference focusing on dermal absorption, cholinesterase inhibition, adverse reproductive effects, and carcinogenicity. The book features contributions from over 40 top scientists and covers topics such as PBPK modeling, cytochrome P-450 metabolism in skin, percutaneous absorption, adverse effects, new skin models, and the role of epidemiology in assessing the hazards of toxicants. Health Risk Assessment is essential for toxicologists, environmental chemists, pharmacologists, risk assessors, and managers working in industrial, pesticide, and pharmaceutical development. The book will also benefit individuals in environmental, regulatory, and registration affairs, as well as academicians and students.
Author: Rhoda G.M. Wang
Publisher: CRC Press
ISBN: 1351361740
Category : Medical
Languages : en
Pages : 544
Get Book Here
Book Description
Health Risk Assessment is a comprehensive reference focusing on dermal absorption, cholinesterase inhibition, adverse reproductive effects, and carcinogenicity. The book features contributions from over 40 top scientists and covers topics such as PBPK modeling, cytochrome P-450 metabolism in skin, percutaneous absorption, adverse effects, new skin models, and the role of epidemiology in assessing the hazards of toxicants. Health Risk Assessment is essential for toxicologists, environmental chemists, pharmacologists, risk assessors, and managers working in industrial, pesticide, and pharmaceutical development. The book will also benefit individuals in environmental, regulatory, and registration affairs, as well as academicians and students.
Author: Rhoda G. M. Wang
Publisher: CRC PressI Llc
ISBN: 9780849373572
Category : Health & Fitness
Languages : en
Pages : 527
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Book Description
1. Pharmacokinetcs, metabolism, and percutaneous penetration of the skin; 2. Route of exposure and toxicological response; 3. Dose, toxicity, and risk assessment; 4. New models in skin research.
Author: Rhoda G.M. Wang
Publisher:
ISBN: 9781138560185
Category :
Languages : en
Pages : 544
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Book Description
SECTION 3: DOSE, TOXICITY, AND RISK ASSESSMENT -- Chapter 21 Incorporating Biological Information into the Assessment of Cancer Risk to Humans Under Various Exposure Conditions and Issues Related to High Background Tumor Incidence Rates -- Chapter 22 Phototoxicity of Topical and Systemic Agents -- Chapter 23 Techniques for Assessing the Health Risks of Dermal Contact with Chemicals in the Environment -- Chapter 24 Interspecies Extrapolation of Toxicological Data -- SECTION 4: NEW MODELS IN SKIN RESEARCH -- Chapter 25 Human Skin Xenografts to Athymic Rodents as a System to Study Toxins Delivered to or Through the Skin -- Chapter 26 The Isolated Perfused Porcine Skin Flap -- SECTION 5: EPIDEMIOLOGIC STUDIES OF ROUTE OF EXPOSURE AND HEALTH EFFECTS -- Chapter 27 Perspectives on Assessment of Risk From Dermal Exposure to Polycyclic Aromatic Hydrocarbons -- Chapter 28 The Paradox of Herbicide 2,4-D Epidemiology -- Chapter 29 A Review of Epidemiologic Studies with Regard to Routes of Exposure to Toxicants -- Index
Author: International Program on Chemical Safety
Publisher: World Health Organization
ISBN: 9241563117
Category : Medical
Languages : en
Pages : 77
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Book Description
The objective of this manual is to provide guidance to risk assessors on the use of quantitative toxicokinetic and toxicodynamic data to address interspecies and interindividual differences in dose and concentration-response assessment. Section 1 focuses on the relevance of this guidance in the context of the broader risk assessment paradigm and other initiatives of the International Program on Chemical Safety (IPCS) project on the Harmonization of Approaches to the Assessment of Risk from Exposure to Chemicals. Technical background material is presented in section 2, followed by generic guidance for the development of chemical-specific adjustment factors in section 3 and accompanying summary figures. Illustrative case-studies are included in an Appendix, and a glossary of terms is also provided.--Publisher's description.
Author: Wayne R. Ott
Publisher: CRC Press
ISBN: 1420012630
Category : Medical
Languages : en
Pages : 554
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Book Description
Written by experts, Exposure Analysis is the first complete resource in the emerging scientific discipline of exposure analysis. A comprehensive source on the environmental pollutants that affect human health, the book discusses human exposure through pathways including air, food, water, dermal absorption, and, for children, non-food ingesti
Author:
Publisher:
ISBN:
Category : Skin absorption
Languages : en
Pages : 188
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Book Description
Author: K. Asante-Duah
Publisher: Springer Science & Business Media
ISBN: 9781402009204
Category : Medical
Languages : en
Pages : 372
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Book Description
In fact, with the control and containment of most infectious conditions and diseases of the past millennium having been achieved in most developed countries, and with the resultant increase in life expectancies, much more attention seems to have shifted to degenerative health problems. Many of the degenerative health conditions have been linked to thousands of chemicals regularly encountered in human living and occupational/work environments. It is important, therefore, that human health risk assessments are undertaken on a consistent basis - in order to determine the potential impacts of the target chemicals on public health.
Author: Rhoda G.M. Wang
Publisher: CRC Press
ISBN: 1351361732
Category : Medical
Languages : en
Pages : 804
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Book Description
Health Risk Assessment is a comprehensive reference focusing on dermal absorption, cholinesterase inhibition, adverse reproductive effects, and carcinogenicity. The book features contributions from over 40 top scientists and covers topics such as PBPK modeling, cytochrome P-450 metabolism in skin, percutaneous absorption, adverse effects, new skin models, and the role of epidemiology in assessing the hazards of toxicants. Health Risk Assessment is essential for toxicologists, environmental chemists, pharmacologists, risk assessors, and managers working in industrial, pesticide, and pharmaceutical development. The book will also benefit individuals in environmental, regulatory, and registration affairs, as well as academicians and students.
Author: Michael S. Roberts
Publisher: CRC Press
ISBN:
Category : Health & Fitness
Languages : en
Pages : 714
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Book Description
The source Dermal Absorption and Toxicity Assessment supplies a state-of-the-art overview of the dermal absorption process, and is divided into six well organized sections. Written by internationally recognized experts in the field, this Second Edition is a complete revised and updated text, covering the wide range of methods used to assess skin absorption and the various governmental and industrial programs concerned with skin permeation and toxicity. These include alternative in silico, in vitro, and in vivo strategies to conduct studies for regulatory requirements. To make room for this new expanded content, the editors are publishing a concurrent text entitled: Dermatological and Cosmetic Development with a concentration on subjects concerned with dermatological and cosmetic therapies
Author: Kofi Asante-Duah
Publisher: Springer
ISBN: 9402410392
Category : Medical
Languages : en
Pages : 603
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Book Description
This book provides a concise, yet comprehensive overview of the many facets relating to human health risk assessments in relation to chemical exposure problems. It presents some very important tools and methodologies that can be used to address chemical exposure and public health risk management problems in a consistent, efficient, and cost-effective manner. On the whole, the book represents a collection and synthesis of the principal elements of the risk assessment process that may be used to more effectively address issues pertaining to human exposures to chemicals found in modern societies. This also includes an elaboration of pertinent risk assessment concepts and techniques/methodologies for performing human health risk assessments. Written for both the novice and the experienced, the subject matter of this book is an attempt at offering a simplified and systematic presentation of public health risk assessment methods and application tools – all these facilitated by a layout that will carefully navigate the user through the major processes involved. A number of illustrative example problems are interspersed throughout the book, in order to help present the book in an easy-to-follow, pragmatic manner.
