Handbook for Chemical Process Research and Development

Handbook for Chemical Process Research and Development PDF Author: Wenyi Zhao
Publisher: CRC Press
ISBN: 1315350203
Category : Medical
Languages : en
Pages : 1170

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Book Description
The Handbook for Chemical Process Research and Development focuses on developing processes for chemical and pharmaceutical industries. Forty years ago there were few process research and development activities in the pharmaceutical industry, partially due to the simplicity of the drug molecules. However, with the increasing structural complexity, especially the introduction of chiral centers into the drug molecules and strict regulations set by the EMA and FDA, process R&D has become one of the critical departments for pharmaceutical companies. This book assists with the key responsibility of process chemists to develop chemical processes for manufacturing pharmaceutical intermediates and final drug substances for clinical studies and commercial production.

Handbook for Chemical Process Research and Development

Handbook for Chemical Process Research and Development PDF Author: Wenyi Zhao
Publisher: CRC Press
ISBN: 1315350203
Category : Medical
Languages : en
Pages : 1170

Get Book

Book Description
The Handbook for Chemical Process Research and Development focuses on developing processes for chemical and pharmaceutical industries. Forty years ago there were few process research and development activities in the pharmaceutical industry, partially due to the simplicity of the drug molecules. However, with the increasing structural complexity, especially the introduction of chiral centers into the drug molecules and strict regulations set by the EMA and FDA, process R&D has become one of the critical departments for pharmaceutical companies. This book assists with the key responsibility of process chemists to develop chemical processes for manufacturing pharmaceutical intermediates and final drug substances for clinical studies and commercial production.

Handbook for Chemical Process Research and Development, Second Edition

Handbook for Chemical Process Research and Development, Second Edition PDF Author: Wenyi Zhao
Publisher: CRC Press
ISBN: 1000859053
Category : Science
Languages : en
Pages : 938

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Book Description
This fully updated second edition reflects the significant changes in process chemistry since the first edition and includes more common process issues such as safety, cost, robustness, and environmental impact. Some areas have made notable progress such as process safety, stereochemistry, new reagents and reagent surrogates. Forty years ago there were few process research and development activities in the pharmaceutical industry, partly due to the simplicity of drug molecules. With increasing structural complexity especially the introduction of chiral centers into drug molecules and stricter regulations, process R&D has become one of the critical departments for pharmaceutical companies. Features: This unique volume now in its second edition is designed to provide readers with an unprecedented strategy and approach which will help chemists and graduate students develop chemical processes in an efficient manner. Promotes an industrial mindset concerning safety and commercial viability when developing methods. The author discusses development strategies with case studies and experimental procedures. Focuses on mechanism-guided process development which provides readers with practical strategies and approaches. Addresses more common process issues such as safety, cost, robustness, and environmental impact. This book provides a new direction for scientists, researchers, and students in materials science and polymer chemistry who seek to better understand the chemistry behind conducting polymers and improve their performance for use in advanced energy applications.

Handbook for Chemical Process Research and Development

Handbook for Chemical Process Research and Development PDF Author: Wenyi Zhao (Chemist)
Publisher:
ISBN: 9781032264615
Category : Drugs
Languages : en
Pages : 0

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Book Description
"This fully updated second edition reflects the significant changes in process chemistry since the first edition and includes more common process issues such as safety, cost, robustness, and environmental impact. Some areas have made notable progress such as process safety, stereochemistry, new reagents and reagent surrogates. Forty years ago there were few process research and development activities in the pharmaceutical industry, partly due to the simplicity of drug molecules. With increasing structural complexity especially the introduction of chiral centers into drug molecules and stricter regulations, process R&D has become one of the critical departments for pharmaceutical companies"--

Handbook of Chemical Process Development

Handbook of Chemical Process Development PDF Author: S. B. Chandalia
Publisher:
ISBN: 9788187070146
Category : Chemical processes
Languages : en
Pages : 310

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Book Description


Practical Process Research & Development

Practical Process Research & Development PDF Author: Neal G. Anderson
Publisher: Academic Press
ISBN: 9781483299778
Category : Science
Languages : en
Pages : 354

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Book Description
This book provides a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries. Process R&D describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. More people are being hired for work in this area as increasing numbers of drug candidates are identified through combinatorial chemistry and high-throughput screening. The book is directed to industrial (primarily organic) chemists, and academicians (particularly those involved in a growing number of start-up companies) and students who need insight into industrial process R&D. Current books do not describe hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." "Practical Process Research and Development" will be a valuable resource for researchers, managers, and graduate students. * Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules" * Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more * Includes over 100 tips for rapid process development * Presents guidelines for implementing and troubleshooting processes

The Chemistry of Process Development in Fine Chemical and Pharmaceutical Industry

The Chemistry of Process Development in Fine Chemical and Pharmaceutical Industry PDF Author: Someswara Rao
Publisher: John Wiley & Sons
ISBN: 047031995X
Category : Technology & Engineering
Languages : en
Pages : 1

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Book Description
This book brings together the chemical strategies used in the optimisation of organic reactions and processes, and highlights the practical and technological options available. This book offers: an encyclopedic treatment of organic chemistry from an industrial, process research and development, and manufacturing point of view plenty of examples to illustrate the scope and limitation of the strategies a comprehensive index organised by topic, reaction type, and reagent an extensive literature survey. This is an essential and comprehensive guide for experienced practitioners of chemical process research and development, fresh recruits to chemical industry R&D divisions, and academics who are interested in interacting with the chemical industry, optimising their synthetic strategies, and enriching the field of atom economy.

Albright's Chemical Engineering Handbook

Albright's Chemical Engineering Handbook PDF Author: Lyle Albright
Publisher: CRC Press
ISBN: 0824753623
Category : Science
Languages : en
Pages : 1930

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Book Description
Taking greater advantage of powerful computing capabilities over the last several years, the development of fundamental information and new models has led to major advances in nearly every aspect of chemical engineering. Albright’s Chemical Engineering Handbook represents a reliable source of updated methods, applications, and fundamental concepts that will continue to play a significant role in driving new research and improving plant design and operations. Well-rounded, concise, and practical by design, this handbook collects valuable insight from an exceptional diversity of leaders in their respective specialties. Each chapter provides a clear review of basic information, case examples, and references to additional, more in-depth information. They explain essential principles, calculations, and issues relating to topics including reaction engineering, process control and design, waste disposal, and electrochemical and biochemical engineering. The final chapters cover aspects of patents and intellectual property, practical communication, and ethical considerations that are most relevant to engineers. From fundamentals to plant operations, Albright’s Chemical Engineering Handbook offers a thorough, yet succinct guide to day-to-day methods and calculations used in chemical engineering applications. This handbook will serve the needs of practicing professionals as well as students preparing to enter the field.

Chemical Process Equipment - Selection and Design (Revised 2nd Edition)

Chemical Process Equipment - Selection and Design (Revised 2nd Edition) PDF Author: James R. Couper
Publisher: Gulf Professional Publishing
ISBN: 0080919723
Category : Technology & Engineering
Languages : en
Pages : 831

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Book Description
A facility is only as efficient and profitable as the equipment that is in it: this highly influential book is a powerful resource for chemical, process, or plant engineers who need to select, design or configures plant sucessfully and profitably. It includes updated information on design methods for all standard equipment, with an emphasis on real-world process design and performance. The comprehensive and influential guide to the selection and design of a wide range of chemical process equipment, used by engineers globally; Copious examples of successful applications, with supporting schematics and data to illustrate the functioning and performance of equipment Revised edition, new material includes updated equipment cost data, liquid-solid and solid systems, and the latest information on membrane separation technology Provides equipment rating forms and manufacturers’ data, worked examples, valuable shortcut methods, rules of thumb, and equipment rating forms to demonstrate and support the design process Heavily illustrated with many line drawings and schematics to aid understanding, graphs and tables to illustrate performance data

Chemical Engineering Design

Chemical Engineering Design PDF Author: Gavin Towler
Publisher: Elsevier
ISBN: 0080966608
Category : Technology & Engineering
Languages : en
Pages : 1320

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Book Description
Chemical Engineering Design, Second Edition, deals with the application of chemical engineering principles to the design of chemical processes and equipment. Revised throughout, this edition has been specifically developed for the U.S. market. It provides the latest US codes and standards, including API, ASME and ISA design codes and ANSI standards. It contains new discussions of conceptual plant design, flowsheet development, and revamp design; extended coverage of capital cost estimation, process costing, and economics; and new chapters on equipment selection, reactor design, and solids handling processes. A rigorous pedagogy assists learning, with detailed worked examples, end of chapter exercises, plus supporting data, and Excel spreadsheet calculations, plus over 150 Patent References for downloading from the companion website. Extensive instructor resources, including 1170 lecture slides and a fully worked solutions manual are available to adopting instructors. This text is designed for chemical and biochemical engineering students (senior undergraduate year, plus appropriate for capstone design courses where taken, plus graduates) and lecturers/tutors, and professionals in industry (chemical process, biochemical, pharmaceutical, petrochemical sectors). New to this edition: Revised organization into Part I: Process Design, and Part II: Plant Design. The broad themes of Part I are flowsheet development, economic analysis, safety and environmental impact and optimization. Part II contains chapters on equipment design and selection that can be used as supplements to a lecture course or as essential references for students or practicing engineers working on design projects. New discussion of conceptual plant design, flowsheet development and revamp design Significantly increased coverage of capital cost estimation, process costing and economics New chapters on equipment selection, reactor design and solids handling processes New sections on fermentation, adsorption, membrane separations, ion exchange and chromatography Increased coverage of batch processing, food, pharmaceutical and biological processes All equipment chapters in Part II revised and updated with current information Updated throughout for latest US codes and standards, including API, ASME and ISA design codes and ANSI standards Additional worked examples and homework problems The most complete and up to date coverage of equipment selection 108 realistic commercial design projects from diverse industries A rigorous pedagogy assists learning, with detailed worked examples, end of chapter exercises, plus supporting data and Excel spreadsheet calculations plus over 150 Patent References, for downloading from the companion website Extensive instructor resources: 1170 lecture slides plus fully worked solutions manual available to adopting instructors

Handbook for Chemical Process Industries

Handbook for Chemical Process Industries PDF Author: Himanshu J Patel
Publisher: CRC Press
ISBN: 1000969673
Category : Science
Languages : en
Pages : 572

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Book Description
Chemical processing industry plays a pivotal role in the economy of a country, as chemicals are required in every sphere of our lives. This book covers chemical processing of dyes, pigments, drugs and pharmaceutical products, fermented products, agrochemicals, explosives, polymers, Period II and III chemicals, chemicals, sugar, coatings, starches, soaps and detergents, paper, pulp, glass, and cement. It includes sources of natural materials, collection process, purification, and extraction of different chemicals from natural materials like petroleum, coal and ores from the Earth. It includes manufacturing details of C1 to C4 and aromatic compounds obtained from natural materials. The book covers both traditional and modern sectors of the chemical processing industry. It provides knowledge on the properties of the chemical and manufacturing process (such as raw materials, chemical reactions, quantitative requirement, flow sheet diagram, procedure) and its uses. The book is based on the author's expertise and has been developed with an awareness of the quantitative requirement for manufacturing chemicals. Data has been collected from industry, thus it will be useful to industry personnel, research groups, academicians and institutional organizations.