Haemostatic Failure in Liver Disease

Haemostatic Failure in Liver Disease PDF Author: P. Fondu
Publisher: Springer Science & Business Media
ISBN: 9780898386400
Category : Medical
Languages : en
Pages : 206

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Book Description
J. DE GROOTE One of the most ominous and troublesome complications of the liver disease is the appearance of hemorrhagic phenomena. Many careful clini­ cal observations about the relationship of liver function and of bilia­ ry tree pathology have been published. A vast amount of research work has been devoted to the subject. The severity of the hemorrhagic disor­ der is usually in relation to the liver disease. In mild chronic hepa­ titis or short lasting obstruction slight subcutaneous or mucosal blee­ ding may (lraw the attention of the patient and the doctor, but they are as such far from dangerous. However in acute hepatic insufficiency, in biliary cirrhosis the bleeding tendency is to be considered as a life threatening complication in about half of the cases. Moreover coagulation disturbances aggravate bleeding not only from ruptured oesophageal or gastric varices but also from gastritis or peptic ulcer. 11enometrorrhagia, epistaxis and gingival bleeding may be very trouble­ some in these conditions. The use of diagnostic procedures sucl. as liver puncture biopsy and peritoneoscopy are often impossible when platelets and prothrombine time are too low. In order to overcome this difficul­ ty a procedure has been worked out taking a biopsy through a trans­ jugular catheter placed in the hepatic vein. If a bleeding from the liver occurs it will be in the circulatory system and not cause any trouble.

Haemostatic Failure in Liver Disease

Haemostatic Failure in Liver Disease PDF Author: P. Fondu
Publisher: Springer Science & Business Media
ISBN: 9780898386400
Category : Medical
Languages : en
Pages : 206

Get Book Here

Book Description
J. DE GROOTE One of the most ominous and troublesome complications of the liver disease is the appearance of hemorrhagic phenomena. Many careful clini­ cal observations about the relationship of liver function and of bilia­ ry tree pathology have been published. A vast amount of research work has been devoted to the subject. The severity of the hemorrhagic disor­ der is usually in relation to the liver disease. In mild chronic hepa­ titis or short lasting obstruction slight subcutaneous or mucosal blee­ ding may (lraw the attention of the patient and the doctor, but they are as such far from dangerous. However in acute hepatic insufficiency, in biliary cirrhosis the bleeding tendency is to be considered as a life threatening complication in about half of the cases. Moreover coagulation disturbances aggravate bleeding not only from ruptured oesophageal or gastric varices but also from gastritis or peptic ulcer. 11enometrorrhagia, epistaxis and gingival bleeding may be very trouble­ some in these conditions. The use of diagnostic procedures sucl. as liver puncture biopsy and peritoneoscopy are often impossible when platelets and prothrombine time are too low. In order to overcome this difficul­ ty a procedure has been worked out taking a biopsy through a trans­ jugular catheter placed in the hepatic vein. If a bleeding from the liver occurs it will be in the circulatory system and not cause any trouble.

Haemostatic Failure in Liver Disease

Haemostatic Failure in Liver Disease PDF Author: P. Fondu
Publisher: Springer Science & Business Media
ISBN: 9400960069
Category : Medical
Languages : en
Pages : 193

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Book Description
J. DE GROOTE One of the most ominous and troublesome complications of the liver disease is the appearance of hemorrhagic phenomena. Many careful clini cal observations about the relationship of liver function and of bilia ry tree pathology have been published. A vast amount of research work has been devoted to the subject. The severity of the hemorrhagic disor der is usually in relation to the liver disease. In mild chronic hepa titis or short lasting obstruction slight subcutaneous or mucosal blee ding may (lraw the attention of the patient and the doctor, but they are as such far from dangerous. However in acute hepatic insufficiency, in biliary cirrhosis the bleeding tendency is to be considered as a life threatening complication in about half of the cases. Moreover coagulation disturbances aggravate bleeding not only from ruptured oesophageal or gastric varices but also from gastritis or peptic ulcer. 11enometrorrhagia, epistaxis and gingival bleeding may be very trouble some in these conditions. The use of diagnostic procedures sucl. as liver puncture biopsy and peritoneoscopy are often impossible when platelets and prothrombine time are too low. In order to overcome this difficul ty a procedure has been worked out taking a biopsy through a trans jugular catheter placed in the hepatic vein. If a bleeding from the liver occurs it will be in the circulatory system and not cause any trouble.

Disorders of Hemostasis

Disorders of Hemostasis PDF Author: Charles Douglas Forbes
Publisher: Saunders
ISBN:
Category : Medical
Languages : en
Pages : 584

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Book Description
This clinical reference provides current and comprehensive material on hemostatic disorders. It covers normal mechanisms of hemostasis, primary disorders of hemostasis, and hemostatic disorders associated with other conditions. Specific chapters address such topics as circulating inhibitors, fibrinolytic bleeding disorders, genetic disorders of blood coagulation, drug-induced disorders of coagulation, psychogenic bleeding, and much more.

Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy PDF Author: John A. Kellum
Publisher: Oxford University Press
ISBN: 019022553X
Category : Medical
Languages : en
Pages : 329

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Book Description
Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance for the management of critically ill patients with acute renal failure, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice.

Vascular Disorders of the Liver

Vascular Disorders of the Liver PDF Author: Dominique Valla
Publisher: Springer Nature
ISBN: 303082988X
Category : Medical
Languages : en
Pages : 376

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Book Description
This book provides a comprehensive account on individually rare, but collectively frequent diseases of the liver. In the first part, conditions such as hepatic vascular malformations, ischemic cholangiopathy, hepatic artery occlusion, sinusoidal conditions and Budd-Chiari syndrome are discussed among others. The second part examines the causes of vascular liver disease namely, coagulation disorders, neoplasm disorders, non-malignant blood disorders, systemic diseases and toxins, among others. The unique expertise of the authors, who are all members of the Vascular Liver Disease Disorders Group, an independent network of researchers with a common interest in Vascular Liver Diseases, are merged for an optimal pragmatic and individualized approach. This book is of interest to a broad range of experts, such as hepatologists, internists, radiologists and angiologists.

Trauma Induced Coagulopathy

Trauma Induced Coagulopathy PDF Author: Hunter B. Moore
Publisher: Springer Nature
ISBN: 3030536068
Category : Medical
Languages : en
Pages : 802

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Book Description
The first edition of this publication was aimed at defining the current concepts of trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It served as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader is provided with a full understanding of the tests that are used to study trauma induced coagulopathy. With the growing interest in understanding and managing coagulation in trauma, this second edition has been expanded to 46 chapters from its original 35 to incorporate the massive global efforts in understanding, diagnosing, and treating trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications is reviewed in detail. The text provides therapeutic strategies to treat specific coagulation abnormalities following severe injury, which goes beyond the first edition that largely was based on describing the mechanisms causing coagulation abnormalities. Trauma Induced Coagulopathy 2nd Edition is a valuable reference to clinicians that are faced with specific clinical challenges when managing coagulopathy.

Hepatology

Hepatology PDF Author: David Zakim
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 862

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Book Description
The thoroughly revised New Edition presents definitive coverage of liver disease from over 100 expert contributors. Streamlined to cover the scientific aspects of liver disease only as they apply to immediate clinical implications, this 2-volume resource presents information on pathology, pathophysiology, and clinical diagnosis and management in a readable, engaging format. From normal liver function and the systemic effects of liver dysfunction, through etiology, clinical features, diagnosis, and treatment, you'll find accurate, up-to-date information page after page.

Perioperative Hemostasis

Perioperative Hemostasis PDF Author: Carlo Enrique Marcucci
Publisher: Springer
ISBN: 3642550045
Category : Medical
Languages : en
Pages : 456

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Book Description
All anesthesiologists are confronted with patients who show bleeding disorders, whether congenital, acquired, or pharmacologically induced. Although many studies, meta-analyses, guidelines, and textbooks have been published on the subject, they mostly cover specific aspects or require a thorough knowledge of hemostasis. The goal of this book is to provide the anesthesiologist with an overview of hemostasis and the mechanisms underlying bleeding and coagulation in general and to assist in the understanding of specific coagulation disorders as they may occur in the various anesthesia subspecialties. It is hoped that, through the provision of practical information and tools, the book will help residents and trained anesthesiologists to manage one of the most frustrating challenges that they face: the bleeding patient. A full understanding of coagulation requires a lifelong career, and this book is not intended to replace the consulting hematologist, whose expert opinion should always be sought. The available procoagulant blood products and drugs all have potentially dangerous side-effects; furthermore, in bleeding disorders pitfalls are frequent and a misdiagnosis can have potentially catastrophic consequences. The aim of the editors is thus instead to enhance the collaboration between the disciplines of Anesthesiology and Hematology.

Non-Vitamin K Antagonist Oral Anticoagulants

Non-Vitamin K Antagonist Oral Anticoagulants PDF Author: Eduard Shantsila
Publisher: Springer
ISBN: 331925460X
Category : Medical
Languages : en
Pages : 82

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Book Description
This book is an essential guide to the medical treatment of thrombosis and presents core principles of anticoagulant therapeutics as well as drug recommendations. Written by recognized experts in the field, this concise, accessible handbook provides a unique and valuable resource in the cardiovascular field, both for those currently in training, and for those already in clinical or research practice.

Oxford Desk Reference: Critical Care

Oxford Desk Reference: Critical Care PDF Author: Carl Waldmann
Publisher: Oxford University Press, USA
ISBN: 0199229589
Category : Medical
Languages : en
Pages : 629

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Book Description
The Oxford Desk Reference: Critical Care allows easy access to evidence-based materials on commonly encountered critical care problems for quick consultation to ensure the optimum management of a particular condition. A concise reference book, it collates key recommendations and presents them in an easily accessible and uniform way.