Great Discoveries in Psychiatry

Great Discoveries in Psychiatry PDF Author: Ronald Chase
Publisher: Logos Verlag Berlin GmbH
ISBN: 3832553479
Category : Medical
Languages : en
Pages : 228

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Book Description
Everyone knows about the celebrated discoveries in physical medicine, yet few people can name a single discovery in psychiatry. This book fills the gap by recounting the paths taken to fifteen breakthroughs in psychiatry. Told here are stories of how an Australian psychiatrist single-handedly discovered an effective medication for mania and why it was never patented; what an eighteenth century physician found beneath the skull of patients residing at a hospital where the infamous Marquis de Sade staged plays; the eery X-rays that revealed the first biomarker for schizophrenia; how magnetic resonance imaging detects damaged nerve bundles by tracking water molecules in the brain; what a pig slaughterhouse contributed to the treatment of depression. And much more. Taken in their entirety, the chapters cover all or most of the major topics in psychiatry, namely care and treatment, diagnostics, biomarkers, and neuroscience. They follow a rough chronological order beginning around the year 1800 and continuing right through to the present. Deeply researched and fully referenced, the language is non-technical. Sixty-six illustrations accompany the text. This book will help people understand where psychiatry has come from and where it is likely headed.

Great Discoveries in Psychiatry

Great Discoveries in Psychiatry PDF Author: Ronald Chase
Publisher: Logos Verlag Berlin GmbH
ISBN: 3832553479
Category : Medical
Languages : en
Pages : 228

Get Book Here

Book Description
Everyone knows about the celebrated discoveries in physical medicine, yet few people can name a single discovery in psychiatry. This book fills the gap by recounting the paths taken to fifteen breakthroughs in psychiatry. Told here are stories of how an Australian psychiatrist single-handedly discovered an effective medication for mania and why it was never patented; what an eighteenth century physician found beneath the skull of patients residing at a hospital where the infamous Marquis de Sade staged plays; the eery X-rays that revealed the first biomarker for schizophrenia; how magnetic resonance imaging detects damaged nerve bundles by tracking water molecules in the brain; what a pig slaughterhouse contributed to the treatment of depression. And much more. Taken in their entirety, the chapters cover all or most of the major topics in psychiatry, namely care and treatment, diagnostics, biomarkers, and neuroscience. They follow a rough chronological order beginning around the year 1800 and continuing right through to the present. Deeply researched and fully referenced, the language is non-technical. Sixty-six illustrations accompany the text. This book will help people understand where psychiatry has come from and where it is likely headed.

Science and Psychiatry

Science and Psychiatry PDF Author: Solomon H. Snyder
Publisher: American Psychiatric Pub
ISBN: 1585628824
Category : Medical
Languages : en
Pages : 494

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Book Description
Solomon Snyder has been instrumental in the establishment of modern psychopharmacology -- as a pioneer in the identification of receptors for neurotransmitters and drugs and in the explanation of the actions of psychotropic agents. Science and Psychiatry is a collection of some of his best scientific papers, publications ranging over forty years that represent important advances in psychopharmacology and molecular biology. Audacious and unanticipated when they first appeared, these papers opened up new areas of understanding and revolutionized the modern study of the brain. Republished here, they show why fundamental research into the "messengers of the mind" is as essential for clinicians as for researchers. Many of these papers have clear clinical relevance, offering insight into modern neuroscience to help make sense of the bewildering array of available psychotropic medications and point the way toward more effective and safer agents. Others describe the underpinnings of psychopharmacology that practitioners need to know, especially regarding the role of receptors in drug action. Each of the nine groups of research articles is accompanied by a commentary by a well-known authority, putting the discoveries in perspective and providing a broad overview of subjects ranging from characterization of the enkephalins to serotonin receptor subtypes. The final set of papers focuses on apoptosis, the general process of cell suicide, where Snyder's work with bilirubin holds promise for treating neurodegenerative disorders. And in a closing piece, "The Audacity Principle in Science," Snyder speculates about factors conducive to creativity and efficacy in scientific discovery. The articles particularly describe four groups of extraordinary discoveries for which Snyder is widely recognized: Identification of opiate receptors, providing keys to understanding pain perception Characterization of the IP3 receptor, exploring its role as a target for lithium treatment in manic-depressive disorders Establishment of nitric oxide as a transmitter in the brain, radically transforming conceptualizations of neurotransmission Discovery that D-serine is the normal stimulus for the glycine site of the NMDA receptor, providing new insight into the regulation of the receptor important for learning and memory Hailed as one of the preeminent scientists of the past twenty years, Snyder is a consummate researcher who confesses to remaining obsessed with the need to "think thoughts no one else has thought before." Science and Psychiatry clearly shows how that urge accounts for the diversity of challenges he has taken on as it conveys the origins of modern psychopharmacologic practice.

Personalized Psychiatry

Personalized Psychiatry PDF Author: Bernhard Baune
Publisher: Academic Press
ISBN: 0128131772
Category : Medical
Languages : en
Pages : 594

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Book Description
Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. - Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics - Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry - Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective

Frontiers in Psychiatry

Frontiers in Psychiatry PDF Author: Yong-Ku Kim
Publisher: Springer Nature
ISBN: 9813297212
Category : Science
Languages : en
Pages : 628

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Book Description
This book reviews key recent advances and new frontiers within psychiatric research and clinical practice. These advances either represent or are enabling paradigm shifts in the discipline and are influencing how we observe, derive and test hypotheses, and intervene. Progress in information technology is allowing the collection of scattered, fragmented data and the discovery of hidden meanings from stored data, and the impacts on psychiatry are fully explored. Detailed attention is also paid to the applications of artificial intelligence, machine learning, and data science technology in psychiatry and to their role in the development of new hypotheses, which in turn promise to lead to new discoveries and treatments. Emerging research methods for precision medicine are discussed, as are a variety of novel theoretical frameworks for research, such as theoretical psychiatry, the developmental approach to the definition of psychopathology, and the theory of constructed emotion. The concluding section considers novel interventions and treatment avenues, including psychobiotics, the use of neuromodulation to augment cognitive control of emotion, and the role of the telomere-telomerase system in psychopharmacological interventions.

Mind Fixers: Psychiatry's Troubled Search for the Biology of Mental Illness

Mind Fixers: Psychiatry's Troubled Search for the Biology of Mental Illness PDF Author: Anne Harrington
Publisher: W. W. Norton & Company
ISBN: 1324001976
Category : Psychology
Languages : en
Pages : 477

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Book Description
“Superb… a nuanced account of biological psychiatry.” —Richard J. McNally In Mind Fixers, “the preeminent historian of neuroscience” (Science magazine) Anne Harrington explores psychiatry’s repeatedly frustrated efforts to understand mental disorder. She shows that psychiatry’s waxing and waning theories have been shaped not just by developments in the clinic and lab, but also by a surprising range of social factors. Mind Fixers recounts the past and present struggle to make mental illness a biological problem in order to lay the groundwork for creating a better future.

The Mental Hygiene Movement

The Mental Hygiene Movement PDF Author: Clifford Whittingham Beers
Publisher:
ISBN:
Category : Mental illness
Languages : en
Pages : 104

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Book Description


The Discovery Of The Unconscious

The Discovery Of The Unconscious PDF Author: Henri F. Ellenberger
Publisher: Basic Books
ISBN: 9780465016730
Category : Psychology
Languages : en
Pages : 0

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Book Description
This classic work is a monumental, integrated view of man's search for an understanding of the inner reaches of the mind. In an account that is both exhaustive and exciting, the distinguished psychiatrist and author demonstrates the long chain of development—through the exorcists, magnetists, and hypnotists—that led to the fruition of dynamic psychiatry in the psychological systems of Janet, Freud, Adler, and Jung.

The Curious History of Medicines in Psychiatry

The Curious History of Medicines in Psychiatry PDF Author: Wallace B. Mendelson
Publisher:
ISBN: 9780578637877
Category :
Languages : en
Pages :

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Book Description
In the years following World War II, there were no effective medicines for schizophrenia, bipolar disorder or major depression. There were not even names for such things- words like 'antipsychotic', 'mood stabilizer','antidepressant' or 'tranquilizer' had not even come into being. Within the next two decades all these types of medicines were developed.Most of these discoveries occurred inadvertently, often with a chance observation by a physician or scientist who was looking for something else. Who would have predicted that war surplus fuel from German V2 rockets would be used to develop a new tuberculosis drug, and that a doctor prescribing it noticed that patients felt more hopeful, and thought this might be useful for depression? Or that a scientist testing a preservative for penicillin noticed that animals became quieter, and wondered if it might be a helpful treatment for human anxiety?In this book Dr. Mendelson, a Distinguished Fellow of the American Psychiatric Association, draws upon forty years of experience studying medicines to describe how they were found, as well as the context of world events and the lives of the discoverers.

The Book of Woe

The Book of Woe PDF Author: Gary Greenberg
Publisher: Penguin
ISBN: 1101621109
Category : Psychology
Languages : en
Pages : 359

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Book Description
“Gary Greenberg has become the Dante of our psychiatric age, and the DSM-5 is his Inferno.” —Errol Morris Since its debut in 1952, the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders has set down the “official” view on what constitutes mental illness. Homosexuality, for instance, was a mental illness until 1973. Each revision has created controversy, but the DSM-5 has taken fire for encouraging doctors to diagnose more illnesses—and to prescribe sometimes unnecessary or harmful medications. Respected author and practicing psychotherapist Gary Greenberg embedded himself in the war that broke out over the fifth edition, and returned with an unsettling tale. Exposing the deeply flawed process behind the DSM-5’s compilation, The Book of Woe reveals how the manual turns suffering into a commodity—and made the APA its own biggest beneficiary.

Anatomy of an Epidemic

Anatomy of an Epidemic PDF Author: Robert Whitaker
Publisher: Crown
ISBN: 0307452433
Category : Psychology
Languages : en
Pages : 418

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Book Description
Updated with bonus material, including a new foreword and afterword with new research, this New York Times bestseller is essential reading for a time when mental health is constantly in the news. In this astonishing and startling book, award-winning science and history writer Robert Whitaker investigates a medical mystery: Why has the number of disabled mentally ill in the United States tripled over the past two decades? Interwoven with Whitaker’s groundbreaking analysis of the merits of psychiatric medications are the personal stories of children and adults swept up in this epidemic. As Anatomy of an Epidemic reveals, other societies have begun to alter their use of psychiatric medications and are now reporting much improved outcomes . . . so why can’t such change happen here in the United States? Why have the results from these long-term studies—all of which point to the same startling conclusion—been kept from the public? Our nation has been hit by an epidemic of disabling mental illness, and yet, as Anatomy of an Epidemic reveals, the medical blueprints for curbing that epidemic have already been drawn up. Praise for Anatomy of an Epidemic “The timing of Robert Whitaker’s Anatomy of an Epidemic, a comprehensive and highly readable history of psychiatry in the United States, couldn’t be better.”—Salon “Anatomy of an Epidemic offers some answers, charting controversial ground with mystery-novel pacing.”—TIME “Lucid, pointed and important, Anatomy of an Epidemic should be required reading for anyone considering extended use of psychiatric medicine. Whitaker is at the height of his powers.” —Greg Critser, author of Generation Rx