Author: Masatake Ōnishi
Publisher: S. Karger AG (Switzerland)
ISBN:
Category : Medical
Languages : en
Pages : 282
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Book Description
In living organisms, glyco-materials (beta-glycans, their oligosaccharides, and glyco-chains) play a decisive role in such biological processes as signal transduction, cell adhesion, fertilization, transport, and immunity. For industrial production, glyco-materials are inexhaustible and renewable resources. beta-glycans, for instance, are essential for the commercial production of food stuffs and other industrial products. The present volume focuses on the glyco-enzymes, which catalyze the reactions (hydrolysis, transfer, and condensation) of glyco-materials and are thus critical for their industrial utilization.
Author: Masatake Ōnishi
Publisher:
ISBN:
Category : Amylases
Languages : en
Pages : 282
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Book Description
Author:
Publisher: Academic Press
ISBN: 0080562868
Category : Science
Languages : en
Pages : 417
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Book Description
Advances in Carbohydrate Chemistry and Biochemistry
Author: Martin Horowitz
Publisher: Elsevier
ISBN: 0323145396
Category : Science
Languages : en
Pages : 579
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Book Description
The Glycoconjugates: Mammalian Glycoproteins and Glycolipids, Volume I is a collaboration of different experts in the field of molecular biology on the subject of glycoconjugates. The text discusses the historical aspect, nomenclature, biosynthesis, and catabolism of glycoconjugates and their role in normal and pathological processes. Also covered are topics such as the purification of glycoproteins; the elucidation of the amino acid sequence of glycoproteins; the glycoproteins found in the different parts of the human body; glycoenzymes; and glycohormones. The book is recommended for molecular biologists, organic chemists, and biochemists who would like to know more about glycolipids and glycoproteins and their applications.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309260833
Category : Science
Languages : en
Pages : 171
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Book Description
A new focus on glycoscience, a field that explores the structures and functions of sugars, promises great advances in areas as diverse as medicine, energy generation, and materials science, this report finds. Glycans-also known as carbohydrates, saccharides, or simply as sugars-play central roles in many biological processes and have properties useful in an array of applications. However, glycans have received little attention from the research community due to a lack of tools to probe their often complex structures and properties. Transforming Glycoscience: A Roadmap for the Future presents a roadmap for transforming glycoscience from a field dominated by specialists to a widely studied and integrated discipline, which could lead to a more complete understanding of glycans and help solve key challenges in diverse fields.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309260868
Category : Science
Languages : en
Pages : 171
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Book Description
A new focus on glycoscience, a field that explores the structures and functions of sugars, promises great advances in areas as diverse as medicine, energy generation, and materials science, this report finds. Glycans-also known as carbohydrates, saccharides, or simply as sugars-play central roles in many biological processes and have properties useful in an array of applications. However, glycans have received little attention from the research community due to a lack of tools to probe their often complex structures and properties. Transforming Glycoscience: A Roadmap for the Future presents a roadmap for transforming glycoscience from a field dominated by specialists to a widely studied and integrated discipline, which could lead to a more complete understanding of glycans and help solve key challenges in diverse fields.
Author: Yanmei Li
Publisher: Frontiers Media SA
ISBN: 2889661202
Category : Science
Languages : en
Pages : 219
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Book Description
Glycans have long been known to be one of the most abundant biological molecules in living organisms. They can function as energy compounds, form structural cell wall/matrix polymers, or exist as oligomers that are attached on proteins, lipids and natural products to influence their properties and function. Because of their important biological roles, glycans have great potential for applications in the development of new drugs, materials, food additives and many other products. However, it is often difficult to directly obtain glycans from natural sources with ideal properties for these applications. Thus, modification of glycan structures for desired properties has emerged as an active area of research. This research area is generally called glycoengineering.
Author: Xiaohuan Xia
Publisher: Frontiers Media SA
ISBN: 2832542913
Category : Medical
Languages : en
Pages : 218
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Book Description
Despite great advances in diagnosis and treatment that we witnessed in the last decades, over a billion people suffer from both respiratory and neurological diseases each year, which poses great threats to the public health and economic burden worldwide. In many instances, the underlying pathogenic mechanisms are still poorly understood, which significantly limits the efficacy of therapeutic methods. In this regard, lines of evidence pinpoint the important role of immunity and inflammation in both respiratory disorders (e.g., pulmonary hypertension, chronic obstructive pulmonary disease, asthma, etc.) and neurological ones (e.g., neurodegenerative diseases, stroke, depression, etc.). The accumulation of inflammatory cells and an excess of cytokines and chemokines at the inflammatory site would result from the disturbance of the body's delicate balance between immunity and tolerance. Therefore, it gives rise to chronic inflammation and autoimmunity underlying the development of both lung and neurological diseases. Furthermore, the inflammation interaction between lung and brain has been identified, suggesting the existence and importance of the lung-brain axis in the regulation of immune responses in the lung and brain that contribute to the onset and progression of both respiratory and neurological diseases. Nevertheless, inflammatory or immunity related risk factors as well novel targets and therapies against inflammation or immunity help early diagnosis and treatment of respiratory and neurological diseases. At present, the full picture of the molecular mechanisms of how immuno-inflammatory activation and the immune cells orchestrate the tissue remodeling leading to respiratory and neurological diseases remains unclear. The identification of inflammatory molecules as therapeutic targets or biomarkers are worth further scrutiny to halt the disease progression and monitor the therapeutic interventions.
Author: C.H. Fuchsman
Publisher: Springer Science & Business Media
ISBN: 9781851660094
Category : Science
Languages : en
Pages : 402
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Book Description
This text is based on papers presented at a Peat Dewatering symposium at Rivere-du-Loup, Quebec, Canada, in June 1985.
Author: Thomas Scheper
Publisher: Springer
ISBN: 3540498117
Category : Science
Languages : en
Pages : 243
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Book Description
The immobilized biocatalyst (IMB) is a key component of biotransformation systems that are used to transform substrates to desired products. The impro- ment of biocatalyst properties has a direct influence on the overall effectiveness of the process based on the biotransformation. The basic catalytic characte- stics of biocatalyst that are followed include kinetic properties, pH optima, stability, and inhibition. The investigation of catalytic properties of immobilized enzymes is still a time consuming procedure and is not always simple. In the 1980s, a major effort was made to standardize the rules by which IMB is char- terized. The Working Party of EFB on immobilized biocatalysts has formul- ed principles of individual methods, among them the requirement of kinetic characterization [1]. It was recommended to use a packed-bed reactor, equipped with temperature control and with infinite flow circulation. The system should be equipped with a post-column unit to measure the time-dependence of the product or substrate concentration [2, 3], the most commonly used analytical methods being spectrophotometry, chemiluminiscence, automatic titration, bioluminiscence, chromatography, polarimetry, and biosensors based on the oxygen electrode. There are two main drawbacks to the application of these methods: 1. The need to vary the analytical principles, depending on the chemical and physical-chemical properties of analytes; 2. In some cases, mainly in the study of hydrolytic enzymes, the natural s- strate must be replaced by an artificial one, that is chromolytic, chromogenic, chemiluminiscent, bioluminiscent, or fluorescent.
