Development of Novel Vaccines

Development of Novel Vaccines PDF Author: Alexander von Gabain
Publisher: Springer Science & Business Media
ISBN: 3709107091
Category : Medical
Languages : en
Pages : 318

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Book Description
“Development of novel vaccines” gives an overview of the tasks in basic research leading to the final product – the vaccine and its applications, belonging to the most complex biologics in the pharmaceutical field. Distinct from most textbooks in the vaccine arena, the current issue focuses on the translational aspect, namely, how research results can be transformed into life-saving medical interventions. Each chapter of the book deals with one important paradigm for the development of novel vaccines, along the value chain towards the final vaccine, and furthermore, with the inevitable tools required for this process. Contributions are prepared by teams of scientists, all of whom are experts in the field, most of them anchored in biomedical organizations devoted to translational culture, thereby lighting the certain topics from different views. This volume is a must read for researchers engaged in vaccine development and who really want to see their research results to become a product.

Development of Novel Vaccines

Development of Novel Vaccines PDF Author: Alexander von Gabain
Publisher: Springer Science & Business Media
ISBN: 3709107091
Category : Medical
Languages : en
Pages : 318

Get Book Here

Book Description
“Development of novel vaccines” gives an overview of the tasks in basic research leading to the final product – the vaccine and its applications, belonging to the most complex biologics in the pharmaceutical field. Distinct from most textbooks in the vaccine arena, the current issue focuses on the translational aspect, namely, how research results can be transformed into life-saving medical interventions. Each chapter of the book deals with one important paradigm for the development of novel vaccines, along the value chain towards the final vaccine, and furthermore, with the inevitable tools required for this process. Contributions are prepared by teams of scientists, all of whom are experts in the field, most of them anchored in biomedical organizations devoted to translational culture, thereby lighting the certain topics from different views. This volume is a must read for researchers engaged in vaccine development and who really want to see their research results to become a product.

Nanocosmetics

Nanocosmetics PDF Author: Jean Cornier
Publisher: Springer
ISBN: 3030165736
Category : Science
Languages : en
Pages : 363

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Book Description
This book addresses the application of nanotechnology to cosmetics. Edited by three respected experts in the field, the book begins with a general overview of the science behind cosmetics and skin care today, and of the status quo of nanotechnology in cosmetics. Subsequent chapters provide detailed information on the different nanoparticles currently used in cosmetics; the production and characterization of nanoparticles and nanocosmetics; and regulatory, safety and commercialization aspects. Given its scope, the book offers an indispensable guide for scientists in academia and industry, technicians and students, as well as a useful resource for decision-makers in the field and consumer organizations. Chapter 6 of this book is available open access under a CC BY 4.0 licence at link.springer.com.

Nanocosmetics

Nanocosmetics PDF Author: Arun Nanda
Publisher: Elsevier
ISBN: 0128222859
Category : Technology & Engineering
Languages : en
Pages : 521

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Book Description
Nanotechnology is key to the design and manufacture of the new generation of cosmetics. Nanotechnology can enhance the performance and properties of cosmetics, including colour, transparency, solubility, texture, and durability. Sunscreen products, such as UV nano-filters, nano-TiO2 and nano-ZnO particles, can offer an advantage over their traditional counterparts due to their broad UV-protection and non-cutaneous side effects. For perfumes, nano-droplets can be found in cosmetic products including Eau de Toilette and Eau de Parfum. Nanomaterials can also be used in cosmetics as transdermal drug delivery systems. By using smart nanocontainers, active compounds such as vitamins, antioxidants, nutrients, and anti-inflammatory, anti-infective agents, can be delivered effectively. These smart nanocontainers are typically related with the smart releasing property for their embedded active substances. These smart releases could be obtained by using the smart coatings as their outer nano-shells. These nano-shells could prevent the direct contact between these active agents and the adjacent local environments. Nanocosmetics: Fundamentals, Applications and Toxicity explores the formulation design concepts and emerging applications of nanocosmetics. The book also focuses on the mitigation or prevention of their potential nanotoxicity, potential global regulatory challenges, and the technical challenges of mass implementation. It is an important reference source for materials scientists and pharmaceutical scientists looking to further their understanding of how nanotechnology is being used for the new generation of cosmetics. Outlines the major fabrication and formulation design concepts of nanoscale products for cosmetic applications Explores how nanomaterials can safely be used for various applications in cosmetic products Assesses the major challenges of using nanomaterials for cosmetic applications on a large scale

Practical Cardiovascular Hemodynamics

Practical Cardiovascular Hemodynamics PDF Author: Elias B. Hanna
Publisher: Demos Medical Publishing
ISBN: 1936287846
Category : Cardiovascular system
Languages : en
Pages : 415

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Book Description
Elias Hanna and D. Luke Glancy provide an in-depth understanding of waveforms and tracings seen in varous disease states as well as pathophysiology behind those findings. Practical issues that are rarely discussed or focused upon in textbooks are highlighted in this book with detailed waveform analysis. Caveats in the hemodynamic assessment of valvular diseases, constriciion, tamponade, pulmonary hypertension, shunt pathology, and right and left ventricular failure are provided. This book also provides case-based and tracing-based quizzes. The reader wil learn to identify disease states and waveform subtleties from single tracings or from case studies. The reader will take the initiative to interpret tracings, understand notches, artifacts, and formulate a diagnosis. This book will feature: Complete presentation of basic and advanced hemodynamics. Numerous case studies allow the reader to learn real-life application of hemodynamic data in clinical decision-making. Quizzes and explanations provides the reader with self-assessment and problem solving skills Over 300 illustrations with detailed discussion.

Nanotoxicity

Nanotoxicity PDF Author: Susai Rajendran
Publisher: Elsevier
ISBN: 012819944X
Category : Science
Languages : en
Pages : 487

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Book Description
Nanotoxicity: Prevention, and Antibacterial Applications of Nanomaterials focuses on the fundamental concepts for cytotoxicity and genotoxicity of nanomaterials. It sheds more light on the underlying phenomena and fundamental mechanisms through which nanomaterials interact with organisms and physiological media. The book provides good guidance for toxic prevention methods and management in the manufacture/application/disposal. The book also discusses the potential applications of nanomaterials-based antibiotics. The potential toxic effects of nanomaterials result not only from the type of base materials, but also from their size/ ligands/surface chemical modifications. This book discusses why different classes of nanomaterials display toxic properties, and what can be done to mitigate this toxicity. It also explores how nanomaterials are being used as antimicrobial agents, being used to purify air and water, and counteract a range of infectious diseases. This is an important reference for materials scientists, environmental scientists and biomedical scientists, who are seeking to gain a greater understanding of how nanomaterials can be used to combat toxic agents, and how the toxicity of nanomaterials themselves can best be mitigated. Explains the underlying phenomena and fundamental mechanisms through which nanomaterials interact with organisms and physiological media Outlines major methods for mitigating and prevention of nanotoxicity Discusses the applications of nanomaterials-based antibiotics

Neurobiology of the Immune System

Neurobiology of the Immune System PDF Author: Angela Clow
Publisher: Elsevier
ISBN: 008049160X
Category : Science
Languages : en
Pages : 457

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Book Description
Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. Provides solid scientific basis to our understanding of the associations between the brain and the immune system the importance of these connections Presents coherent development from cellular and molecular neuroimmune communication to social and health considerations, including psychological intervention Addresses the theory that there is a neurobiology of the immune system

Structural Biology in Immunology

Structural Biology in Immunology PDF Author: Chaim Putterman
Publisher: Academic Press
ISBN: 0128033703
Category : Medical
Languages : en
Pages : 192

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Book Description
Structural Biology in Immunology, Structure/Function of Novel Molecules of Immunologic Importance delivers important information on the structure and functional relationships in novel molecules of immunologic interest. Due to an increasingly sophisticated understanding of the immune system, the approach to the treatment of many immune-mediated diseases, including multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, and inflammatory bowel disease has been dramatically altered. Furthermore, there is an increasing awareness of the critical role of the immune system in cancer biology. The improved central structure function relationships presented in this book will further enhance our ability to understand what defects in normal individuals can lead to disease. Describes novel/recently discovered immunomodulatory proteins, including antibodies and co-stimulatory or co-inhibitory molecules Emphasizes new biologic and small molecule drug design through the exploration of structure-function relationship Features a collaborative editorial effort, involving clinical immunologists and structural biologists Provides useful and practical insights on developing the necessary links between basic science and clinical therapy in immunology Gives interested parties a bridge to learn about computer modeling and structure based design principles

Nanofabrication for Smart Nanosensor Applications

Nanofabrication for Smart Nanosensor Applications PDF Author: Fernando Gomes
Publisher: Elsevier
ISBN: 0128235551
Category : Technology & Engineering
Languages : en
Pages : 474

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Book Description
Nanofabrication for Smart Nanosensor Applications addresses the design, manufacture and applications of a variety of nanomaterials for sensing applications. In particular, the book explores how nanofabrication techniques are used to create more efficient nanosensors, examines their major applications in biomedicine and environmental science, discusses the fundamentals of how nanosensors work, explores different nanofabrication techniques, and comments on toxicity and safety issues relating to the creation of nanosensors using certain nanomaterial classes. This book is an important resource for materials scientists and engineers who want to make materials selection decisions for the creation of new nansensor devices. Summarizes current research and applications of a variety of nanofabrication techniques for the creation of efficient sensing devices Provides readers with an understanding of surfaces and interfaces, a key challenge for those working on hybrid nanomaterials, carbon nanotubes, graphene, polymers and liquid crystal electro-optical imaging Discusses the variability and sight recognition of biopolymers, such as DNA molecules, which offer a wide range of opportunities for the self-organization of nanostructures into much more complex patterns

Nano-Optics

Nano-Optics PDF Author: Sabu Thomas
Publisher: Elsevier
ISBN: 0128183934
Category : Technology & Engineering
Languages : en
Pages : 376

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Book Description
Nano-Optics: Fundamentals, Experimental Methods, and Applications offers insights into the fundamentals and industrial applications of nanoscale light-emitting materials and their composites. This book serves as a reference, offering an overview of existing research, with a particular focus on industrial applications. Nano-optics is the branch of nanoscience and nanotechnology that deals with interaction of light with nanoscale objects. This book explores the materials, structure, manufacturing techniques, and industrial applications of nano-optics. The applications discussed include healthcare, communication, astronomy, and satellites. Explains the major manufacturing techniques for light-emitting nanoscale materials Discusses how nanoscale optical materials are being used in a range of industrial applications Assesses the challenges of using nano-optics in a mass-production context

Nanomaterials for Clinical Applications

Nanomaterials for Clinical Applications PDF Author: Costas Demetzos
Publisher: Elsevier
ISBN: 0128168765
Category : Technology & Engineering
Languages : en
Pages : 322

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Book Description
Nanomaterials in Clinical Medicine: Case Studies in Nanomedicines focuses on the nanomaterials that can be formulated as drug delivery vehicles, such as liposomes, micelles, nanoemulsions and nanogels. Their physicochemical, morphological, thermo-dynamical and nanotoxicological properties are analyzed with respect to the design and development of drug delivery nanosystems for the encapsulation of an active pharmaceutical ingredient and its controlled release. Each chapter covers basic properties, the nanosystem (e.g., liposomes), the added value in drug delivery and targeting, and future perspectives. Case studies and examples of how nanomaterials are being used in clinical medicine, including marketed liposomal medicines and medical utility and regimens are also included. Particular attention is given to new nanocarriers, such as elastic liposomes, lipid polymeric hybrid nanoparticles, organogel, nanofibers carbon nanomaterials, quantum dots and inorganic nanoparticles. This book is an important information source for those wanting to increase their understanding of what major nanomaterials are being used to create more effective drug delivery systems. Summarizes the major nanomaterials used in clinical medicine, explaining how their properties make them suitable for this purpose Explains how nanomaterials are used to create increasingly efficient drug delivery vehicles Includes real-life examples, demonstrating how nanomaterials are being used in medical practice