Gene-Based Therapies for Pediatric Blood Diseases, An Issue of Hematology/Oncology Clinics of North America, E-Book PDF Download
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Author: Nirali N. Shah
Publisher: Elsevier Health Sciences
ISBN: 0323987761
Category : Medical
Languages : en
Pages : 273
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Book Description
In this issue of Hematology/Oncology Clinics, guest editors Drs. Sung-Yun Pai and Nirali N. Shah bring their considerable expertise to the topic of Gene-Based Therapies for Pediatric Blood Diseases. Top experts in the field cover key topics such as CAR T-cell therapy: current status; engineered T cells; NK-cell therapy; hemoglobinopathies: beta-thalassemia, sickle cell disease; hemophilia A/B; primary immunodeficiencies; and more. Contains 14 relevant, practice-oriented topics including the evolution of gene therapy; viral vectors in hematopoietic stem cell gene therapy; gene editing in hematopoietic stem cells; nonintegrating vectors and engineered capsids; regulatory aspects of gene therapy; and more. Provides in-depth clinical reviews on gene-based therapies for pediatric blood diseases, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Author: Nirali N. Shah
Publisher: Elsevier Health Sciences
ISBN: 0323987761
Category : Medical
Languages : en
Pages : 273
Get Book Here
Book Description
In this issue of Hematology/Oncology Clinics, guest editors Drs. Sung-Yun Pai and Nirali N. Shah bring their considerable expertise to the topic of Gene-Based Therapies for Pediatric Blood Diseases. Top experts in the field cover key topics such as CAR T-cell therapy: current status; engineered T cells; NK-cell therapy; hemoglobinopathies: beta-thalassemia, sickle cell disease; hemophilia A/B; primary immunodeficiencies; and more. Contains 14 relevant, practice-oriented topics including the evolution of gene therapy; viral vectors in hematopoietic stem cell gene therapy; gene editing in hematopoietic stem cells; nonintegrating vectors and engineered capsids; regulatory aspects of gene therapy; and more. Provides in-depth clinical reviews on gene-based therapies for pediatric blood diseases, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Author: Sung-Yun Pai, MD
Publisher: Elsevier
ISBN: 9780323987752
Category : Medical
Languages : en
Pages : 240
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Book Description
In this issue of Hematology/Oncology Clinics, guest editors Drs. Sung-Yun Pai and Nirali N. Shah bring their considerable expertise to the topic of Gene-Based Therapies for Pediatric Blood Diseases. Top experts in the field cover key topics such as CAR T-cell therapy: current status; engineered T cells; NK-cell therapy; hemoglobinopathies: beta-thalassemia, sickle cell disease; hemophilia A/B; primary immunodeficiencies; and more. Contains 14 relevant, practice-oriented topics including the evolution of gene therapy; viral vectors in hematopoietic stem cell gene therapy; gene editing in hematopoietic stem cells; nonintegrating vectors and engineered capsids; regulatory aspects of gene therapy; and more. Provides in-depth clinical reviews on gene-based therapies for pediatric blood diseases, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Author: Daniel E. Bauer
Publisher: Elsevier Health Sciences
ISBN: 0323546692
Category : Medical
Languages : en
Pages :
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Book Description
This issue of Hematology/Oncology Clinics will focus on Gene Therapy. Topics include, but are not limited to Historical Perspective and Current Renaissance, Integrating Vectors, Nonintegrating Vectors, Gene Editing, Conditioning Therapies for Autologous HSCT, Approaches to Immunodeficiency, Approaches to Hemoglobinopathy, Approaches to Hemophilia, Hematopoietic Gene Therapies for Neurologic and Metabolic Disease, Gene Therapy Approaches to HIV and other Infectious Diseases, HSC Approaches to Cancer, and Gene Modified T Cell Therapies for Cancer.
Author: Rachael Grace
Publisher: Elsevier Health Sciences
ISBN: 0323673341
Category : Medical
Languages : en
Pages :
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Book Description
This issue of Hematology/Oncology Clinics, Guest Edited by Drs. Rachael Grace and Russell E. Ware, will focus on Pediatric Hematology. This issue is one of six selected for the year by the series Consulting Editors, George P. Canellos and H. Franklin Bunn. Topics include, but are not limited to, Rare Congenital Hemolytic Anemias, Sickle Cell, Thalassemia, Neutropenia and rare leukocyte disorders in children, Primary and Secondary Immune cytopenias, Disorders of Iron overload, Disorders of Iron metabolism, Approach to Hemophilia in a Changing Treatment Landscape, Von Willebrand disease, Inherited platelet disorders, Thrombosis, Diagnostic evaluation and medical approach to complications and treatment of vascular anomalies, New approaches and trials in Transfusion Medicine, and Updates in Neonatal Hematology.
Author: Max J. Coppes
Publisher: Clinics: Internal Medicine
ISBN: 9781437722024
Category : Medical
Languages : en
Pages : 0
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Book Description
This issue highlights some of the exciting new developments in pediatric oncology and hematology. Three articles are devoted to pediatric leukemia, which remains the most common form of pediatric cancer. Specifically, articles address ALL, AML, and leukemia in patients with Down syndrome. Other articles that address pediatric oncology include CNS tumors and neuroblastoma as well as advances in cancer immunotherapy. A very interesting article addresses the challenges experienced by adults who survived a childhood cancer. The hematology articles in this issue cover aspects that most clinicians see on a regular basis-sickle cell disease, thalassemia, and hemophilia, and ITP.
Author: Rachael Grace
Publisher: Elsevier
ISBN: 9780323673334
Category :
Languages : en
Pages :
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Book Description
This issue of Hematology/Oncology Clinics, Guest Edited by Drs. Rachael Grace and Russell E. Ware, will focus on Pediatric Hematology. This issue is one of six selected for the year by the series Consulting Editors, George P. Canellos and H. Franklin Bunn. Topics include, but are not limited to, Rare Congenital Hemolytic Anemias, Sickle Cell, Thalassemia, Neutropenia and rare leukocyte disorders in children, Primary and Secondary Immune cytopenias, Disorders of Iron overload, Disorders of Iron metabolism, Approach to Hemophilia in a Changing Treatment Landscape, Von Willebrand disease, Inherited platelet disorders, Thrombosis, Diagnostic evaluation and medical approach to complications and treatment of vascular anomalies, New approaches and trials in Transfusion Medicine, and Updates in Neonatal Hematology.
Author: Catherine S. Manno
Publisher: Elsevier Health Sciences
ISBN: 0323261191
Category : Medical
Languages : en
Pages : 345
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Book Description
This issue will assist the practicing pediatrician with providing evidence-based care to children with common, rare, inherited and acquired hematological disorders whom they regularly see in general pediatric practice. The information in this edition will support a general pediatrician’s understanding of recently developed diagnostic and therapeutic tools--for instance, techniques for the assessment of transfusional iron overload in chronically transfused patients – resulting in better surveillance of medication side effects and improved support for patients who are prescribed with complex chelation regimens. New, improved therapeutic approaches to treatment of children with venous thromboembolic disease have recently been introduced; affected patients often require close monitoring in their communities through the general pediatrician whose practice will be enhanced by information that has been prepared by pediatric specialists with pediatric patients in mind.
Author: Michael A. Weiner
Publisher: Elsevier Health Sciences
ISBN: 9781560534440
Category : Medical
Languages : en
Pages : 260
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Book Description
Utilizes the proven Secrets Series format to present questions and answers in a convenient, readable, concise manner The text is intended to introduce the reader to the field of pediatric hematology/oncology.Each chapter will emphasize diagnosis, clinical management, therapeutics, and innovative concepts for the future. Highlights of the text include the following chapters: experimental therapeutics, the application of bone marrow and stem cell transplants for pediatric patients, and genetic and molecular diagnostics. There is a section dealing with quality of life and death issues such as supportive care, psychosocial aspects of care of the child with cancer, palliative care, and management of the dying child. Other chapters relate and differentiate disease entities based upon the age of the patient, newborn through adolescent. Each topic covered will discuss diagnosis, clinical management, therapeutics, and innovative concepts for the future. Concise answers that also feature the authors' pearls, tips, memory aids, and "secrets" Bulleted lists and pertinent tables for quick review and reference Succinct chapters written by experts in pediatric hematology and oncology All the most important "need-to-know" questions and answers in the proven format of the highly acclaimed Secrets Series Thorough, highly detailed index
Author: Sophie Lanzkron
Publisher: Elsevier Health Sciences
ISBN: 0323986641
Category : Medical
Languages : en
Pages : 289
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Book Description
In this issue of Hematology/Oncology Clinics, guest editors Drs. Sophie Lanzkron and Jane Little bring their considerable expertise to the topic of Sickle Cell Syndromes. Top experts in the field cover key topics such as structural racism and impact on sickle cell disease (SCD); pathophysiology and biomarkers of SCD; genetic modifiers of SCD; allogeneic transplant and gene therapy: reproductive health; chronic pain; and more. Contains 16 relevant, practice-oriented topics including innovative therapies, addressing challenging complications, novel science on mechanisms of disease; preventing cognitive decline in people with SCD; quality of life in SCD; and more. Provides in-depth clinical reviews on sickle cell syndromes, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Author: Caron A Jacobson
Publisher: Elsevier Health Sciences
ISBN: 0443183015
Category : Medical
Languages : en
Pages : 193
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Book Description
In this issue of Hematology/Oncology Clinics, guest editors Drs. Caron A. Jacobson and Parth S. Shah bring their considerable expertise to the topic of CAR T-Cell Therapy. Top experts in the field discuss the multiple ways CAR T-cell therapy can be used to help fight a variety of cancers, such as diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, mantle cell lymphoma, multiple myeloma, and B-cell acute lymphoblastic leukemia (ALL). Contains 12 practice-oriented topics including CAR T-cells in aggressive B-cell lymphomas; CAR T-cells in multiple myeloma; CAR T-cells in AML; mechanisms of resistance of CAR T-cell therapy; the role of CAR T-cell therapy in the era of bispecific antibodies; and more. Provides in-depth clinical reviews on CAR T-cell therapy, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
