Functional Genomics of Intramolluscan Stages of the Human Blood Fluke Schistosoma Mansoni PDF Download
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Author: Jon J. Vermeire
Publisher:
ISBN:
Category :
Languages : en
Pages : 154
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Book Description
Author: Jon J. Vermeire
Publisher:
ISBN:
Category :
Languages : en
Pages : 154
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Book Description
Author: Arnon Dias Jurberg
Publisher: Frontiers Media SA
ISBN: 2889195562
Category : Ecology
Languages : en
Pages : 156
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Book Description
Schistosomes are human parasites distributed worldwide in tropical and sub-tropical latitudes, especially in developing countries and impoverished regions. These neglected tropical disease (NTD) pathogens causes debilitating illnesses, which include hepatosplenomegaly, hepatic fibrosis, haemorrhagic necrotic ulcerations in the intestinal mucosa, urogenital tract diseases, in addition to cardiopulmonary, renal and neurologic lesions due to egg accumulation in the liver, intestines, uro-genital tissues and other sites. Urogenital schistosomiasis is a risk factor for bladder cancer and increases the risk of transmission of HIV infection. Despite extensive effort to control this NTD over the years, deployment on a considerable scale of commercially available drugs in endemic populations has induced the emergence of resistant isolates and raised the need to identify new targets for alternative therapies. Because of the availability of genomes of the three major species of human schistosomiasis, and through advances in functional genomics and live imaging, studies on schistosomes have now come into focus as models to investigate adaptations to parasitism and developmental biology of trematodes and cestodes, and indeed flatworms and Lophotrochozoans, at large. This Research Topic aims at gathering state-of-art essays on schistosome genetics, genetics, pathobiology and immunobiology. It also aims to highlight advances in understanding of the host-parasite relationship, in paradigms that address this NTD, and to discuss new perspectives and advances in chemotherapy and immunoprophylaxis.
Author: K. V. Galaktionov
Publisher: Springer Science & Business Media
ISBN: 9401732477
Category : Science
Languages : en
Pages : 605
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Book Description
The book by K. V. Galaktionov and A. A. Dobrovolskij maintains the tra- tion of monographs devoted to detailed coverage of digenetic tr matodes in the tradition of B. Dawes (1946) and T. A. Ginetsinskaya (1968). In this - spect, the book is traditional in both its form and content. In the beginning (Chapter 1), the authors provide a consistent analysis of the morphological features of all life cycle stages. Importantly, they present a detailed char- terization of sporocysts and rediae whose morphological-functional orga- zation has never been comprehensively described in modern literature. The authors not only list morphological characteristics, but also analyze the functional significance of different morphological structures and hypothesize about their evolution. Special attention is given to specific features of m- phogenesis in all stages of the trematode life cycle. On this basis, the authors provide several original suggestions about the possible origins of morp- logical evolution of the parthenogenetic (asexual) and the hermaphroditic generations. This is followed by a detailed consideration of the various m- phological-biological adaptations that ensure the successful completion of the complex life cycles of these parasites (Chapter 2). Life cycles inherent in different trematodes are subject to a special analysis (Chapter 3). The authors distinguish several basic types of life cycles and suggest an original interpretation of their evolutionary origin. Chapter 4 features the analysis of structure and the dynamics of trematode populations and is unusual for a monograph of this type.
Author: Barrie G. M. Jamieson
Publisher: CRC Press
ISBN: 1315351900
Category : Medical
Languages : en
Pages : 550
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Book Description
Apart from malaria, schistosomiasis is the most prevalent parasitic infection in the world. It affects more than 200 million people in 76 tropical and subtropical countries, causing great suffering and resulting in thousands of deaths. Written by world authorities, this book examines many aspects of the biology, pathology, and control of the schistosoma parasite. Ranging in topic from infection in Pharaonic Egypt, through DNA relationships and biological systems, to advances in development of vaccines against the parasite, this book is a comprehensive text written for researchers and medical professionals alike.
Author: Jon Patrick Boyle
Publisher:
ISBN:
Category :
Languages : en
Pages : 242
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Book Description
Author: John H. Byrne
Publisher: Oxford University Press
ISBN: 0190456787
Category : Science
Languages : en
Pages : 608
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Book Description
Invertebrates have proven to be extremely useful model systems for gaining insights into the neural and molecular mechanisms of sensory processing, motor control and higher functions such as feeding behavior, learning and memory, navigation, and social behavior. A major factor in their enormous contributions to neuroscience is the relative simplicity of invertebrate nervous systems. In addition, some invertebrates, primarily the molluscs, have large cells, which allow analyses to take place at the level of individually identified neurons. Individual neurons can be surgically removed and assayed for expression of membrane channels, levels of second messengers, protein phosphorylation, and RNA and protein synthesis. Moreover, peptides and nucleotides can be injected into individual neurons. Other invertebrate model systems such as Drosophila and Caenorhabditis elegans offer tremendous advantages for obtaining insights into the neuronal bases of behavior through the application of genetic approaches. The Oxford Handbook of Invertebrate Neurobiology reviews the many neurobiological principles that have emerged from invertebrate analyses, such as motor pattern generation, mechanisms of synaptic transmission, and learning and memory. It also covers general features of the neurobiology of invertebrate circadian rhythms, development, and regeneration and reproduction. Some neurobiological phenomena are species-specific and diverse, especially in the domain of the neuronal control of locomotion and camouflage. Thus, separate chapters are provided on the control of swimming in annelids, crustaea and molluscs, locomotion in hexapods, and camouflage in cephalopods. Unique features of the handbook include chapters that review social behavior and intentionality in invertebrates. A chapter is devoted to summarizing past contributions of invertebrates to the understanding of nervous systems and identifying areas for future studies that will continue to advance that understanding.
Author: Burton J. Bogitsh
Publisher: Elsevier
ISBN: 0080547257
Category : Science
Languages : en
Pages : 481
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Book Description
Human Parasitology emphasizes the medical aspects of the topic, while incorporating functional morphology, physiology, biochemistry, and immunology to enhance appreciation of the diverse implications of parasitism. Bridging the gap between classical clinical parasitology texts and traditional encyclopaedic treatises, Human Parasitology appeals to students interested not only in the medical aspects of Parasitology but also to those who require a solid foundation in the biology of parasites. Updated and expanded reference section New chapter on Immunology Additional SEM and TEM micrographs Professionally drawn life cycle illustrations Addition of “Host Immune Response section for each organism
Author: G.W. Esch
Publisher: Springer Science & Business Media
ISBN: 9401123527
Category : Science
Languages : en
Pages : 349
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Book Description
Series Editor: Peter Calow, Department of Zoology, University of Sheffield, England The main aim of this series will be to illustrate and to explain the way organisms 'make a living' in nature. At the heart of this - their functional biology - is the way organisms acquire and then make use of resources in metabolism, movement, growth, reproduction, and so on. These processes will form the fundamental framework of all the books in the series. Each book will concentrate on a particular taxon (species, family, class or even phylum) and will bring together information on the form, physiology, ecology and evolutionary biology of the group. The aim will be not only to describe how organisms work, but also to consider why they have come to work in that way. By concentration on taxa which are well known, it is hoped that the series will not only illustrate the success of selection, but also show the constraints imposed upon it by the physiological, morphological and developmental limitations of the groups. Another important feature of the series will be its organismic orientation. Each book will emphasize the importance of functional integration in the day to-day lives and the evolution of organisms. This is crucial since, though it may be true that organisms can be considered as collections of gene determined traits, they nevertheless interact with their environment as integrated wholes and it is in this context that individual traits have been subjected to natural selection and have evolved.
Author: Robert T. Dillon
Publisher: Cambridge University Press
ISBN: 1139426990
Category : Science
Languages : en
Pages : 523
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Book Description
All aspects of the ecology of freshwater molluscs are discussed in this unique volume. Extensively referenced and providing a synthesis of work from the nineteenth century onwards, this book will appeal to professional ecologists, evolutionary biologists and parasitologists interested in these diverse invertebrates.
Author: Leslie H. Chappell
Publisher: Springer Science & Business Media
ISBN: 1468478087
Category : Science
Languages : en
Pages : 237
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Book Description
THIS BOOK HAS BEEN DEVELOPED FROM A SHORT LECTURE COURSE GIVEN to advanced undergraduate students as part of a general introduction to the subject of parasitology for zoologists. The book is written for the undergraduate who has no previous experience of parasitology and little background in either biochemistry or physiology. It is not a long book, and students will have to consult some of the more detailed textbooks in parasitology and physiology to gain a full understanding of the topics considered here. My objective in writing this book is to introduce the breadth of parasite physiology, leaving the reader to obtain a depth of knowledge by his own library research. Each chapter covers a single topic or related topics in physiological parasitology, and the variable length of the chapters reflects the amount of research interest that has been generated over the last few decades. It is to be hoped that by use of this book students will develop an interest in some of the more neglected areas and be stimulated to make good some of the more glaring deficiencies in our current knowledge. I should like to acknowledge with gratitude the assistance of my colleagues Dr 1. Barrett, Dr R. A. Klein, Dr A. W. Pike and Dr R. A.
