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Author: Richard A. Rettig
Publisher: Oxford University Press
ISBN: 9780199748242
Category : Medical
Languages : en
Pages : 368
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Book Description
In the late 1980s, a promising new treatment for breast cancer emerged: high-dose chemotherapy with autologous bone marrow transplantation or HDC/ABMT. By the 1990s, it had burst upon the oncology scene and disseminated rapidly before having been carefully evaluated. By the time published studies showed that the procedure was ineffective, more than 30,000 women had received the treatment, shortening their lives and adding to their suffering. This book tells of the rise and demise of HDC/ABMT for metastatic and early stage breast cancer, and fully explores the story's implications, which go well beyond the immediate procedure, and beyond breast cancer, to how we in the United States evaluate other medical procedures, especially life-saving ones. It details how the factors that drove clinical use--patient demand, physician enthusiasm, media reporting, litigation, economic exploitation, and legislative and administrative mandates--converged to propel the procedure forward despite a lack of proven clinical effectiveness. It also analyzes the limited effect of technology assessments before randomized clinical trials evaluated decisively the procedure and the ramifications of this system on healthcare today. Sections of the book consider the initial conditions surrounding the emergence of the new breast cancer treatment, the drivers of clinical use, and the struggle for evidence-based medicine. A concluding section considers the significance of the story for our healthcare system.
Author: Richard A. Rettig
Publisher: Oxford University Press
ISBN: 9780199748242
Category : Medical
Languages : en
Pages : 368
Get Book
Book Description
In the late 1980s, a promising new treatment for breast cancer emerged: high-dose chemotherapy with autologous bone marrow transplantation or HDC/ABMT. By the 1990s, it had burst upon the oncology scene and disseminated rapidly before having been carefully evaluated. By the time published studies showed that the procedure was ineffective, more than 30,000 women had received the treatment, shortening their lives and adding to their suffering. This book tells of the rise and demise of HDC/ABMT for metastatic and early stage breast cancer, and fully explores the story's implications, which go well beyond the immediate procedure, and beyond breast cancer, to how we in the United States evaluate other medical procedures, especially life-saving ones. It details how the factors that drove clinical use--patient demand, physician enthusiasm, media reporting, litigation, economic exploitation, and legislative and administrative mandates--converged to propel the procedure forward despite a lack of proven clinical effectiveness. It also analyzes the limited effect of technology assessments before randomized clinical trials evaluated decisively the procedure and the ramifications of this system on healthcare today. Sections of the book consider the initial conditions surrounding the emergence of the new breast cancer treatment, the drivers of clinical use, and the struggle for evidence-based medicine. A concluding section considers the significance of the story for our healthcare system.
Author: Dane Calloway
Publisher:
ISBN: 9781737655817
Category :
Languages : en
Pages :
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Book Description
Author: Daniel Callahan
Publisher: Rutgers University Press
ISBN: 9780813526744
Category : Health care reform
Languages : en
Pages : 340
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Book Description
This text exposes the cause of the health care crisis and proposes an alternative to make care affordable and available to all. It shows how the quest for perfection is the core of the crisis, and suggests a medicine that bows to the limits of human nature and gives priority to meeting basic needs.
Author: Tim Bouverie
Publisher:
ISBN: 0451499840
Category : Biography & Autobiography
Languages : en
Pages : 530
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Book Description
"A new history of the British appeasement of the Third Reich on the eve of World War II"--
Author: Goldwin Smith
Publisher: New York : J.W. Lovell Company ; Toronto : Willing & Williamson
ISBN:
Category : Government ownership
Languages : en
Pages : 76
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Book Description
Author: Gerald N. Rosenberg
Publisher: University of Chicago Press
ISBN: 0226726681
Category : Political Science
Languages : en
Pages : 541
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Book Description
In follow-up studies, dozens of reviews, and even a book of essays evaluating his conclusions, Gerald Rosenberg’s critics—not to mention his supporters—have spent nearly two decades debating the arguments he first put forward in The Hollow Hope. With this substantially expanded second edition of his landmark work, Rosenberg himself steps back into the fray, responding to criticism and adding chapters on the same-sex marriage battle that ask anew whether courts can spur political and social reform. Finding that the answer is still a resounding no, Rosenberg reaffirms his powerful contention that it’s nearly impossible to generate significant reforms through litigation. The reason? American courts are ineffective and relatively weak—far from the uniquely powerful sources for change they’re often portrayed as. Rosenberg supports this claim by documenting the direct and secondary effects of key court decisions—particularly Brown v. Board of Education and Roe v. Wade. He reveals, for example, that Congress, the White House, and a determined civil rights movement did far more than Brown to advance desegregation, while pro-choice activists invested too much in Roe at the expense of political mobilization. Further illuminating these cases, as well as the ongoing fight for same-sex marriage rights, Rosenberg also marshals impressive evidence to overturn the common assumption that even unsuccessful litigation can advance a cause by raising its profile. Directly addressing its critics in a new conclusion, The Hollow Hope, Second Edition promises to reignite for a new generation the national debate it sparked seventeen years ago.
Author: Jason Sautel
Publisher: Thomas Nelson
ISBN: 1400216486
Category : Biography & Autobiography
Languages : en
Pages : 206
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Book Description
He helped save people every day—but he had no idea how to save himself. Jason Sautel had it all. Confident in his abilities and trusted by his fellow firefighters, he was making a name for himself on the streets of Oakland, California. His adrenaline-fueled job even helped him forget the pain of his childhood—until the day he looked into the eyes of a jumper on the Bay Bridge and came face to face with a darkness he knew would take him down as well. In the following months, a series of traumatic emergency calls—some successful, others impossible-to-forget failures—drove Jason deeper into depression. Even as he continued his lifesaving work, he realized he could never rescue everyone, and he had no idea how to save himself. In the end, Jason was forced to confront the truth: only the relentless power of love could pull him back from his own deadly fall. Action-packed, spiritually honest, and surprisingly romantic, The Rescuer transports readers inside the pulse-pounding world of firefighting and into the heart of a man who needed to be broken before he could finally be made whole.
Author: Curtis Hutson
Publisher: Sword of the Lord Publishers
ISBN: 9780873982795
Category : Belief and doubt
Languages : en
Pages : 24
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Book Description
Author: Peter Greer
Publisher: Baker Books
ISBN: 1493435930
Category : Religion
Languages : en
Pages : 256
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Book Description
Hope for Leaders Facing Burnout and Discouragement Around the world, discouragement erodes the vitality of organizations. Visionaries often succumb to cynicism. Zealous advocates give up. Leaders coast as their passion for the cause grows cold. Grounded in research, this book is an invitation for followers of Jesus to sustain hope in long-term service. It's about moving past the false hope of idealism and the faint hope of disillusionment to discover true Christian hope. You will gain encouragement through the study of the book of Jeremiah woven throughout as the authors explore how the Lord prophetically met and sustained Jeremiah during his lifetime of faithfulness despite literally nothing going as he'd hoped. Glean further inspiration by reading the stories of Christian leaders from around the globe: Zimbabwe, Haiti, Guatemala, Poland, Palestine, the Philippines, India, Zambia, and Lebanon. For this is a moment when we need the global Church's perspective and influence. Don't give up and don't check out. These are confounding and perilous days, yet God's sustaining presence can bring joy, hope, and encouragement even amid heartache and disappointment.
Author: Roger Scruton
Publisher: Oxford University Press
ISBN: 9780199798995
Category : Philosophy
Languages : en
Pages : 240
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Book Description
Ranging widely over human history and culture, from ancient Greece to the current global economic downturn, Scruton makes a counterintuitive yet persuasive case that optimists and idealists -- with their ignorance about the truths of human nature and human society, and their naive hopes about what can be changed -- have wrought havoc for centuries. Scruton's argument is nuanced, however, and his preference for pessimism is not a dark view of human nature; rather his is a 'hopeful pessimism' which urges that instead of utopian efforts to reform human society or human nature, we focus on the only reform that we can truly master -- the improvement of ourselves through the cultivation of our better instincts. Written in Scruton's trademark style-- erudite, sweeping in scope across centuries and cultures, and unafraid to offend-- this book is sure to intrigue and provoke readers concerned with the state of Western culture, the nature of human beings, and the question of whether social progress is truly possible.
