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Author: Om V. Singh
Publisher: John Wiley & Sons
ISBN: 1118394119
Category : Science
Languages : en
Pages : 696
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Book Description
Explores the utility and potential of extremophiles in sustainability and biotechnology Many extremophilic bio-products are already used as life-saving drugs. Until recently, however, the difficulty of working with these microbes has discouraged efforts to develop extremophilic microbes as potential drug reservoirs of the future. Recent technological advances have opened the door to exploring these organisms anew as sources of products that might prove useful in clinical and environmental biotechnology and drug development. Extremophiles features outstanding articles by expert scientists who shed light on broad-ranging areas of progress in the development of smart therapeutics for multiple disease types and products for industrial use. It bridges technological gaps, focusing on critical aspects of extremolytes and the mechanisms regulating their biosynthesis that are relevant to human health and bioenergy, including value-added products of commercial significance as well as other potentially viable products. This groundbreaking guide: Introduces the variety of extremophiles and their extremolytes including extremozymes Provides an overview of the methodologies used to acquire extremophiles Reviews the literature on the diversity of extremophiles Offers tools and criteria for data interpretation of various extremolytes/extremozymes Discusses experimental design problems associated with extremophiles and their therapeutic implications Explores the challenges and possibilities of developing extremolytes for commercial purposes Explains the FDA's regulations on certain microbial bio-products that will be of interest to potential industrialists Extremophiles is an immensely useful resource for graduate students and researchers in biotechnology, clinical biotechnology, microbiology, and applied microbiology.
Author: Om V. Singh
Publisher: John Wiley & Sons
ISBN: 1118394119
Category : Science
Languages : en
Pages : 696
Get Book Here
Book Description
Explores the utility and potential of extremophiles in sustainability and biotechnology Many extremophilic bio-products are already used as life-saving drugs. Until recently, however, the difficulty of working with these microbes has discouraged efforts to develop extremophilic microbes as potential drug reservoirs of the future. Recent technological advances have opened the door to exploring these organisms anew as sources of products that might prove useful in clinical and environmental biotechnology and drug development. Extremophiles features outstanding articles by expert scientists who shed light on broad-ranging areas of progress in the development of smart therapeutics for multiple disease types and products for industrial use. It bridges technological gaps, focusing on critical aspects of extremolytes and the mechanisms regulating their biosynthesis that are relevant to human health and bioenergy, including value-added products of commercial significance as well as other potentially viable products. This groundbreaking guide: Introduces the variety of extremophiles and their extremolytes including extremozymes Provides an overview of the methodologies used to acquire extremophiles Reviews the literature on the diversity of extremophiles Offers tools and criteria for data interpretation of various extremolytes/extremozymes Discusses experimental design problems associated with extremophiles and their therapeutic implications Explores the challenges and possibilities of developing extremolytes for commercial purposes Explains the FDA's regulations on certain microbial bio-products that will be of interest to potential industrialists Extremophiles is an immensely useful resource for graduate students and researchers in biotechnology, clinical biotechnology, microbiology, and applied microbiology.
Author: Joseph Seckbach
Publisher: John Wiley & Sons
ISBN: 1119591686
Category : Science
Languages : en
Pages : 416
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Book Description
The data in this book are new or updated, and will serve also as Origin of Life and evolutionary studies. Endospores of bacteria have a long history of use as model organisms in astrobiology, including survival in extreme environments and interplanetary transfer of life. Numerous other bacteria as well as archaea, lichens, fungi, algae and tiny animals (tardigrades, or water bears) are now being investigated for their tolerance to extreme conditions in simulated or real space environments. Experimental results from exposure studies on the International Space Station and space probes for up to 1.5 years are presented and discussed. Suggestions for extaterrestrial energy sources are also indicated. Audience Researchers and graduate students in microbiology, biochemistry, molecular biology and astrobiology, as well as anyone interested in the search for extraterrestrial life and its technical preparations.
Author: Pabulo H Rampelotto
Publisher: Springer
ISBN: 331913521X
Category : Science
Languages : en
Pages : 726
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Book Description
Aimed at research scientists and biotechnologists, this book is an essential reading for those working with extremophiles and their potential biotechnological application. Here, we provide a comprehensive and reliable source of information on the recent advances and challenges in different aspects of the theme. Written in an accessible language, the book is also a recommended as reference text for anyone interested in this thriving field of research. Over the last decades, the study of extremophiles has provided ground breaking discoveries that challenge our understanding of biochemistry and molecular biology. In the applied side, extremophiles and their enzymes have spawned a multibillion dollar biotechnology industry, with applications spanning biomedical, pharmaceutical, industrial, environmental, and agricultural sectors. Taq DNA polymerase (which was isolated from Thermus aquaticus from a geothermal spring in Yellowstone National Park) is the most well-known example of the potential biotechnological application of extremophiles and their biomolecules. Indeed, the application of extremophiles and their biologically active compounds has opened a new era in biotechnology. However, despite the latest advances, we are just in the beginning of exploring the biotechnological potentials of extremophiles.
Author: Charles Gerday
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 458
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Book Description
A detailed overview of the current state of knowledge about this special group of organisms. - Serves as an essential volume for a variety of scientists, including microbiologists, biochemists, physiologists, biotechnology specialists, ecologists, and physical scientists such as chemists and astronomers.
Author: Richa Salwan
Publisher: Academic Press
ISBN: 0128183233
Category : Science
Languages : en
Pages : 388
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Book Description
Physiological and Biotechnological Aspects of Extremophiles highlights the current and topical areas of research in this rapidly growing field. Expert authors from around the world provide the latest insights into the mechanisms of these fascinating organisms use to survive.The vast majority of extremophiles are microbes which include archaea, bacteria and some eukaryotes. These microbes live under chemical and physical extremes that are usually lethal to cellular molecules, yet they manage to survive and even thrive. Extremophiles have important practical uses. They are a valuable source of industrially important enzymes and recent research has revealed novel mechanisms and biomolecular structures with a broad range of potential applications in biotechnology, biomining, and bioremediation.Aimed at research scientists, students, microbiologists, and biotechnologists, this book is an essential reading for scientists working with extremophiles and a recommended reference text for anyone interested in the microbiology, bioprospecting, biomining, biofuels, and extremozymes of these organisms. - Shows the implications of the physiological adaptations of microbes from extreme habitats that are largely contributed by their biomolecules from basic to applied research - Provides in-depth knowledge of genomic plasticity and proteome of different extremophiles - Gives detailed and comprehensive insight about use of genetic engineering as well as genome editing for industrial applications
Author: Joseph Seckbach
Publisher: Springer Science & Business Media
ISBN: 940076488X
Category : Science
Languages : en
Pages : 626
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Book Description
Many Microorganisms and some macro-organisms can live under extreme conditions. For example, high and low temperature, acidic and alkaline conditions, high salt areas, high pressure, toxic compounds, high level of ionizing radiation, anoxia and absence of light, etc. Many organisms inhabit environments characterized by more than one form of stress (Polyextremophiles). Among them are those who live in hypersaline and alkaline, hot and acidic, cold/hot and high hydrostatic pressure, etc. Polyextremophiles found in desert regions have to copy with intense UV irradiation and desiccation, high as well as low temperatures, and low availability of water and nutrients. This book provides novel results of application to polyextremophiles research ranging from nanotechnology to synthetic biology to the origin of life and beyond.
Author: Gunjal, Aparna B.
Publisher: IGI Global
ISBN: 1799891461
Category : Science
Languages : en
Pages : 473
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Book Description
Extremophiles are organisms that are able to live in extreme conditions due to their unique physiological and genetic adaptations. Extremophiles are harnessed for their extremozymes that have wide applications in biotechnology, pharmaceutics, and industry. Recent developments in genomics and proteomics have helped unravel the mechanism of survival, physiological adaptation, and genomics structure of extremophiles. Physiology, Genomics, and Biotechnological Applications of Extremophiles covers innovative developments in understanding the physiology and biochemistry of extremophiles using the -omics perspective, focuses on the advancement in mechanisms of the extremophiles that makes them able to survive under extreme conditions, and discusses the applications of extremophiles in astrobiology. Covering topics such as genomics and the history and identification of extremophiles, it is ideal for students, professors, researchers, academicians, microbiologists, agricultural scientists, and biotechnologists.
Author: Charles Gerday
Publisher: EOLSS Publications
ISBN: 1905839944
Category : Science
Languages : en
Pages : 382
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Book Description
Extremophiles is a component of Encyclopedia of Biological, Physiological and Health Sciences in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. The extremophiles represent some of the most fascinating organisms on Earth for the simple reason that they inhabit extreme environments characterized by physical and (or) chemical properties which render them totally inhospitable for most of the other organisms. The work has been sub-divided into 6 main topics related to the above mentioned environmental conditions. These topics consist of a general introduction and of several more specialized chapters that have been written by scientists prominent in the field. The chapters cover the description of the biotopes and inhabiting species, their specific characteristics as well as what we know about the molecular mechanisms which constitute the fundamentals of the resistance and adaptation of extremophiles to extreme conditions. The theme “Extremophiles” is headed by two chapters introducing the subject for non-specialists in the field, one covering the basic concepts and the other one giving an overview of the biotopes. These three volumes are aimed at the following five major target audiences: University and College students Educators, Professional practitioners, Research personnel and Policy analysts, managers, and decision makers and NGOs.
Author: Ravi V. Durvasula
Publisher: CRC Press
ISBN: 1351650734
Category : Medical
Languages : en
Pages : 584
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Book Description
Highly recommended by CHOICE, Oct 2018 Extremophiles are nature’s ultimate survivors, thriving in environments ranging from the frozen Antarctic to abyssal hot hydrothermal vents. Their lifeforms span bacteria to fishes, and are categorized as halophiles from hypersaline environments, acidophiles from acidic waters, psychrophiles from cold habitats, and thermophiles from warm waters. Extremophiles: From Biology to Biotechnology comprehensively covers the basic biology, physiology, habitats, secondary metabolites for bioprospecting, and biotechnology of these extreme survivors. The chapters focus on the novel genetic and biochemical traits that lend these organisms to biotechnological applications. Couples studies of marine extremophile biology/genomics and extremophile culture for biotechnological applications with the latest advances in bio-prospecting and bio-product development Includes practical experiments that a laboratory can use to replicate extreme habitats for research purposes Presents latest advances in extremophile genomics to give the reader a better understanding of the regulatory mechanisms of extremophiles Offers insights into the production of commercially important extremozymes, carotenoids, bioactive compounds and secondary metabolites of medicinal value. This unique guide serves as a resource for biotechnologists who wish to explore extremophiles for their commercial potential, as well as a valuable reference for teaching undergraduate, graduate and postgraduate students.
Author: Prasanti Babu
Publisher: Springer
ISBN: 3319128086
Category : Medical
Languages : en
Pages : 58
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Book Description
Extremophiles are known to thrive under harsh environmental conditions. Many extremophilic bio-products are already used as life-saving drugs. Recent technological advancements of systems biology have opened the door to explore these organisms anew as sources of products that might prove useful in clinical, environmental and drug development.
