Experimental Design for Biologists

Experimental Design for Biologists PDF Author: David J. Glass
Publisher: CSHL Press
ISBN: 0879697350
Category : Biology
Languages : en
Pages : 211

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Book Description
The effective design of scientific experiments is critical to success, yet graduate students receive very little formal training in how to do it. Based on a well-received course taught by the author, Experimental Design for Biologistsfills this gap. Experimental Design for Biologistsexplains how to establish the framework for an experimental project, how to set up a system, design experiments within that system, and how to determine and use the correct set of controls. Separate chapters are devoted to negative controls, positive controls, and other categories of controls that are perhaps less recognized, such as “assumption controls†and “experimentalist controls†. Furthermore, there are sections on establishing the experimental system, which include performing critical “system controls†. Should all experimental plans be hypothesis-driven? Is a question/answer approach more appropriate? What was the hypothesis behind the Human Genome Project? What color is the sky? How does one get to Carnegie Hall? The answers to these kinds of questions can be found in Experimental Design for Biologists. Written in an engaging manner, the book provides compelling lessons in framing an experimental question, establishing a validated system to answer the question, and deriving verifiable models from experimental data. Experimental Design for Biologistsis an essential source of theory and practical guidance in designing a research plan.

Experimental Design for Biologists

Experimental Design for Biologists PDF Author: David J. Glass
Publisher: CSHL Press
ISBN: 0879697350
Category : Biology
Languages : en
Pages : 211

Get Book Here

Book Description
The effective design of scientific experiments is critical to success, yet graduate students receive very little formal training in how to do it. Based on a well-received course taught by the author, Experimental Design for Biologistsfills this gap. Experimental Design for Biologistsexplains how to establish the framework for an experimental project, how to set up a system, design experiments within that system, and how to determine and use the correct set of controls. Separate chapters are devoted to negative controls, positive controls, and other categories of controls that are perhaps less recognized, such as “assumption controls†and “experimentalist controls†. Furthermore, there are sections on establishing the experimental system, which include performing critical “system controls†. Should all experimental plans be hypothesis-driven? Is a question/answer approach more appropriate? What was the hypothesis behind the Human Genome Project? What color is the sky? How does one get to Carnegie Hall? The answers to these kinds of questions can be found in Experimental Design for Biologists. Written in an engaging manner, the book provides compelling lessons in framing an experimental question, establishing a validated system to answer the question, and deriving verifiable models from experimental data. Experimental Design for Biologistsis an essential source of theory and practical guidance in designing a research plan.

Cell and Molecular Biology

Cell and Molecular Biology PDF Author: Gerald Karp
Publisher: Wiley
ISBN: 9780471389132
Category : Science
Languages : en
Pages : 856

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Book Description
Balances coverage of the concepts of cell and molecular biology, using examples of experimentation to support those concepts. As experimental techniques become more diverse and complex, it is increasingly necessary to identify individual studies that have a broad impact on our understanding of cell biology. This text describes in detail some of the key experimental findings, along with the original data and figures.

Biological & Agricultural Index

Biological & Agricultural Index PDF Author:
Publisher:
ISBN:
Category : Agriculture
Languages : en
Pages : 1064

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Book Description


Development of Sea Urchins, Ascidians, and Other Invertebrate Deuterostomes: Experimental Approaches

Development of Sea Urchins, Ascidians, and Other Invertebrate Deuterostomes: Experimental Approaches PDF Author: Charles A. Ettensohn
Publisher: Gulf Professional Publishing
ISBN: 9780124802797
Category : Science
Languages : en
Pages : 948

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Book Description
This book provides a practical guide to experimental methods for studying the development of invertebrate deuterostomes, such as sea urchins, ascidians, hemichordates, and amphioxus. These model organisms are of contemporary and historical importance to the study of developmental biology, particularly genomic research. The chapters provide detailed experimental protocols that cover a broad range of topics in modern experimental methods. Topics covered range from rearing embryos to the care of adult animals, while also presenting the basic experimental methods including light and electron microscopy, used to study gene expression, transgenics, reverse genetics, and genomic approaches. * Covers a wide range of methods, from classical embryology through modern genomics * Discusses animals related to vertebrates, providing a valuable evolutionary perspective * Includes a practical guide to the use of sea urchins in the teaching laboratory

Experimental Cell and Molecular Biology

Experimental Cell and Molecular Biology PDF Author: John S. Choinski
Publisher: McGraw-Hill Science, Engineering & Mathematics
ISBN:
Category : Medical
Languages : en
Pages : 246

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Book Description
Combining classical cell biology experiments with modern molecular experiments, "Experimental Cell and Molecular Biology has been developed for your upper-level, cellular and molecular biology laboratory.

Molecular Biology of the Cell 6E - The Problems Book

Molecular Biology of the Cell 6E - The Problems Book PDF Author: John Wilson
Publisher: Garland Science
ISBN: 1317497279
Category : Science
Languages : en
Pages : 985

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Book Description
The Problems Book helps students appreciate the ways in which experiments and simple calculations can lead to an understanding of how cells work by introducing the experimental foundation of cell and molecular biology. Each chapter reviews key terms, tests for understanding basic concepts, and poses research-based problems. The Problems Book has be

Molecular Biology of the Cell

Molecular Biology of the Cell PDF Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0

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Book Description


Karp's Cell Biology

Karp's Cell Biology PDF Author: Gerald Karp
Publisher: John Wiley & Sons
ISBN: 1119454174
Category : Science
Languages : en
Pages : 885

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Book Description
Karp's Cell Biology, Global Edition continues to build on its strength at connecting key concepts to the experiments that reveal how we know what we know in the world of Cell Biology. This classic text explores core concepts in considerable depth, often adding experimental detail. It is written in an inviting style to assist students in handling the plethora of details encountered in the Cell Biology course. In this edition, two new co-authors take the helm and help to expand upon the hallmark strengths of the book, improving the student learning experience.

The Cell Biology of Stem Cells

The Cell Biology of Stem Cells PDF Author: Eran Meshorer
Publisher: Springer Science & Business Media
ISBN: 1441970371
Category : Science
Languages : en
Pages : 246

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Book Description
Stem cells have been gaining a lot of attention in recent years. Their unique potential to self-renew and differentiate has turned them into an attractive model for the study of basic biological questions such as cell division, replication, transcription, cell fate decisions, and more. With embryonic stem (ES) cells that can generate each cell type in the mammalian body and adult stem cells that are able to give rise to the cells within a given lineage, basic questions at different developmental stages can be addressed. Importantly, both adult and embryonic stem cells provide an excellent tool for cell therapy, making stem cell research ever more pertinent to regenerative medicine. As the title The Cell Biology of Stem Cells suggests, our book deals with multiple aspects of stem cell biology, ranging from their basic molecular characteristics to the in vivo stem cell trafficking of adult stem cells and the adult stem-cell niche, and ends with a visit to regeneration and cell fate reprogramming. In the first chapter, “Early embryonic cell fate decisions in the mouse”, Amy Ralson and Yojiro Yamanaka describe the mechanisms that support early developmental decisions in the mouse pre-implantation embryo and the current understanding of the source of the most immature stem cell types, which includes ES cells, trophoblast stem (TS) cells and extraembryonic endoderm stem (XEN) cells.

Key Experiments in Practical Developmental Biology

Key Experiments in Practical Developmental Biology PDF Author: Manuel Marí-Beffa
Publisher: Cambridge University Press
ISBN: 9780521833158
Category : Science
Languages : en
Pages : 412

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Book Description
Originally published in 2005, this unique resource presents 27 easy-to-follow laboratory exercises for use in student practical classes in developmental biology. These experiments provide key insights into developmental questions, and many of them are described by the leaders in the field who carried out the original research. This book intends to bridge the gap between experimental work and the laboratory classes taken at the undergraduate and post-graduate levels. All chapters follow the same format, taking the students from materials and methods, through results and discussion, so that they learn the underlying rationale and analysis employed in the research. The book will be an invaluable resource for graduate students and instructors teaching practical developmental biology courses. Chapters include teaching concepts, discussion of the degree of difficulty of each experiment, potential sources of failure, as well as the time required for each experiment to be carried out in a class with students.