Inhibitory Synaptic Plasticity PDF Download
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Author: Melanie A. Woodin
Publisher: Springer Science & Business Media
ISBN: 1441969780
Category : Medical
Languages : en
Pages : 191
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Book Description
This volume will explore the most recent findings on cellular mechanisms of inhibitory plasticity and its functional role in shaping neuronal circuits, their rewiring in response to experience, drug addiction and in neuropathology. Inhibitory Synaptic Plasticity will be of particular interest to neuroscientists and neurophysiologists.
Author: Melanie A. Woodin
Publisher: Springer Science & Business Media
ISBN: 1441969780
Category : Medical
Languages : en
Pages : 191
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Book Description
This volume will explore the most recent findings on cellular mechanisms of inhibitory plasticity and its functional role in shaping neuronal circuits, their rewiring in response to experience, drug addiction and in neuropathology. Inhibitory Synaptic Plasticity will be of particular interest to neuroscientists and neurophysiologists.
Author: Takao K. Hensch
Publisher: Springer Science & Business Media
ISBN: 1461500397
Category : Medical
Languages : en
Pages : 286
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Book Description
A new perspective on brain function depends upon an understanding of the interaction and integration of excitation and inhibition. A recent surge in research activity focused on inhibitory interneurons now makes a more balanced view possible. Technological advances such as improved imaging methods, visualized patch-clamp recording, multiplex single-cell PCR, and gene-targeted deletion or knock-in mice are some of the novel tools featured in this book. This book will provide an integrated view of neuron function, operating in a balanced regime of excitation and inhibition. It is a timely contribution emphasizing how this balance is established, maintained, and modified from the molecular to system levels. The broad spectrum of topics from molecular to cellular and system/computational neuroscience will appeal to a wide audience of advanced graduate students, post-docs, and faculty. Moreover, this book this book features active young researchers from around the world, who are currently educating the brain scientists of tomorrow.
Author: Carson Chow
Publisher: Elsevier
ISBN: 9780444517920
Category : Language Arts & Disciplines
Languages : en
Pages : 876
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Book Description
1. E. Marder, Experimenting with theory -- 2. A. Borysuk and J. Rinzel, Understanding neuronal dynamics by geometrical dissection of minimal models -- 3. D. Terman, Geometry singular perturbation analysis of neuronal dynamics -- 4. G. Mato, Theory of neural synchrony -- 5. M. Shelley, Some useful numerical techniques for simulating integrate-and-fire networks -- 6. D. Golomb, Propagation of pulses in cortical networks: the single-spike approximation -- 7. M. Tsodyks, Activity-dependent transmission in neocortical synapses -- 8. H. Sompolinsky and J. White, Theory of large recurrent networks: from spikes to behavior -- 9. C. van Vreeswijk, Irregular activity in large networks of neurons -- 10. N. Brunel, Network models of memory -- 11. P. Bressloff, Pattern formation in visual cortex -- 12. F. Wolf, Symmetry breaking and pattern selection in visual cortical development -- 13. A. Treves and Y. Roudi, On the evolution of the brain -- 14. E. Brown, Theory of point processes for neural syst ...
Author: Albert Cheung-Hoi Yu
Publisher: Springer
ISBN: 3319945939
Category : Medical
Languages : en
Pages : 313
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Book Description
This edition of Advances in Neurobiology brings together experts in the emerging field of Systems Neuroscience to present an overview of this area of research. Topics covered include: how different neural circuits analyze sensory information, form perceptions of the external world, make decisions, and execute movements; how nerve cells behave when connected together to form neural networks; the relationship between molecular and cellular approaches to understanding brain structure and function; the study of high-level mental functions; and studying brain pathologies and diseases with Systems Neuroscience. A hierarchy of biological complexity arises from the genome, transcriptome, proteome, organelles, cells, synapses, circuits, brain regions, the whole brain, and behaviour. The best way to study the brain, the most complex organ in the body composed of 100 billion cells with trillions of interconnections, is with a Systems Biology approach. Systems biology is an inter-disciplinary field that focuses on complex interactions within biological systems to reveal 'emergent properties' - properties of cells and groups of cells functioning as a system whose actual and theoretical description is only possible using Systems Biology techniques.
Author: Nigel W. Daw
Publisher: Springer Science & Business Media
ISBN: 1475769407
Category : Medical
Languages : en
Pages : 362
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Book Description
As the first introductory-level text in its field, Visual Development offers a comprehensive understanding of the development of the visual system and the effects of visual deprivation. The material is treated from the behavioral, anatomical, and physiological points of view. Complete with ample illustrations and a helpful glossary, this text is invaluable for graduate students, optometry students, and ophthalmology residents as well as for experts in related fields.
Author: Jeffrey Noebels
Publisher: OUP USA
ISBN: 0199746540
Category : Medical
Languages : en
Pages : 1258
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Book Description
Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.
Author: Li Zhaoping
Publisher: Oxford University Press, USA
ISBN: 0199564663
Category : Medical
Languages : en
Pages : 397
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Book Description
Vision science has grown hugely in the past decades, but there have been few books showing readers how to adopt a computional approach to understanding visual perception, along with the underlying mechanisms in the brain. This book explains the computational principles and models of biological visual processing, and in particular, primate vision.
Author: Nicholas T. Carnevale
Publisher: Cambridge University Press
ISBN: 1139447831
Category : Medical
Languages : en
Pages : 399
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Book Description
The authoritative reference on NEURON, the simulation environment for modeling biological neurons and neural networks that enjoys wide use in the experimental and computational neuroscience communities. This book shows how to use NEURON to construct and apply empirically based models. Written primarily for neuroscience investigators, teachers, and students, it assumes no previous knowledge of computer programming or numerical methods. Readers with a background in the physical sciences or mathematics, who have some knowledge about brain cells and circuits and are interested in computational modeling, will also find it helpful. The NEURON Book covers material that ranges from the inner workings of this program, to practical considerations involved in specifying the anatomical and biophysical properties that are to be represented in models. It uses a problem-solving approach, with many working examples that readers can try for themselves.
Author: Janko Samardzic
Publisher: BoD – Books on Demand
ISBN: 9535138219
Category : Medical
Languages : en
Pages : 139
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Book Description
This book collates the contributions of a selected number of neuroscientists that are interested in the molecular, preclinical, and clinical aspects of neurotransmission research. The seven chapters in this book address the latest research/review data related to GABA/glutamate system's organization and function, the structure of receptors, subtypes and their ligands, as well as the translational approach and clinical implications. The book offers readers a rich collection of data regarding current and future applications of GABA and glutamate neurotransmission, including promising research strategies and potential clinical benefits.
Author: Adam C. Errington
Publisher: Springer
ISBN: 149391426X
Category : Medical
Languages : en
Pages : 301
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Book Description
GABA is the principal inhibitory neurotransmitter in the CNS and acts via GABAA and GABAB receptors. Recently, a novel form of GABAA receptor-mediated inhibition, termed “tonic” inhibition, has been described. Whereas synaptic GABAA receptors underlie classical “phasic” GABAA receptor-mediated inhibition (inhibitory postsynaptic currents), tonic GABAA receptor-mediated inhibition results from the activation of extrasynaptic receptors by low concentrations of ambient GABA. Extrasynaptic GABAA receptors are composed of receptor subunits that convey biophysical properties ideally suited to the generation of persistent inhibition and are pharmacologically and functionally distinct from their synaptic counterparts. This book highlights ongoing work examining the properties of recombinant and native extrasynaptic GABAA receptors and their preferential targeting by endogenous and clinically relevant agents. In addition, it emphasizes the important role of extrasynaptic GABAA receptors in GABAergic inhibition throughout the CNS and identifies them as a major player in both physiological and pathophysiological processes.
