Author: Charles Richard Marshall
Publisher: Jones & Bartlett Publishers
ISBN:
Category : Medical
Languages : en
Pages : 180

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Book Description
This book is especially designed for first- or second-year college courses on evolution.

Author: Michel Morange
Publisher: Harvard University Press
ISBN: 0674245253
Category : Science
Languages : en
Pages : 529

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Book Description
In this masterful account, a historian of science surveys the molecular biology revolution, its origin and continuing impact. Since the 1930s, a molecular vision has been transforming biology. Michel Morange provides an incisive and overarching history of this transformation, from the early attempts to explain organisms by the structure of their chemical components, to the birth and consolidation of genetics, to the latest technologies and discoveries enabled by the new science of life. Morange revisits A History of Molecular Biology and offers new insights from the past twenty years into his analysis. The Black Box of Biology shows that what led to the incredible transformation of biology was not a simple accumulation of new results, but the molecularization of a large part of biology. In fact, Morange argues, the greatest biological achievements of the past few decades should still be understood within the molecular paradigm. What has happened is not the displacement of molecular biology by other techniques and avenues of research, but rather the fusion of molecular principles and concepts with those of other disciplines, including genetics, physics, structural chemistry, and computational biology. This has produced decisive changes, including the discoveries of regulatory RNAs, the development of massive scientific programs such as human genome sequencing, and the emergence of synthetic biology, systems biology, and epigenetics. Original, persuasive, and breathtaking in its scope, The Black Box of Biology sets a new standard for the history of the ongoing molecular revolution.

Author: Masatoshi Nei
Publisher: Oxford University Press
ISBN: 0199881227
Category : Science
Languages : en
Pages : 444

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Book Description
During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth. Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees, statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical examples using the computer program MEGA2 that is provided.

Author: Motoo Kimura
Publisher: Cambridge University Press
ISBN: 1139935674
Category : Science
Languages : en
Pages : 388

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Book Description
Motoo Kimura, as founder of the neutral theory, is uniquely placed to write this book. He first proposed the theory in 1968 to explain the unexpectedly high rate of evolutionary change and very large amount of intraspecific variability at the molecular level that had been uncovered by new techniques in molecular biology. The theory - which asserts that the great majority of evolutionary changes at the molecular level are caused not by Darwinian selection but by random drift of selectively neutral mutants - has caused controversy ever since. This book is the first comprehensive treatment of this subject and the author synthesises a wealth of material - ranging from a historical perspective, through recent molecular discoveries, to sophisticated mathematical arguments - all presented in a most lucid manner.

Author: Lindell Bromham
Publisher: Oxford University Press, USA
ISBN:
Category : Science
Languages : en
Pages : 394

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Book Description
The story in DNA, or, What kind of information can I get from DNA? -- The immortal germline, or, How do I get DNA samples? -- We are all mutants, or, How do I identify individuals? -- Endless copies, or, How do I amplify DNA? -- Descent with modification, or, How do I detect natural selection? -- Origin of species, or, How do I align DNA sequences? -- Tree of life, or, How do I construct a phylogeny? -- Tempo and mode, or, How do I estimate molecular dates? -- You are a scientist, or, What do I do now?

Author: Felix Guattari
Publisher: Semiotext(e)
ISBN:
Category : History
Languages : en
Pages : 500

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Book Description
The post-'68 psychoanalyst and philosopher visits a newly democratic Brazil in 1982 and meets future President Luis Ignacia Lula da Silva: a guide to the radical thought and optimism at the root of today's Brazil. Yes, I believe that there is a multiple people, a people of mutants, a people of potentialities that appears and disappears, that is embodied in social, literary, and musical events.... I think that we're in a period of productivity, proliferation, creation, utterly fabulous revolutions from the viewpoint of this emergence of a people. That's molecular revolution: it isn't a slogan or a program, it's something that I feel, that I live....—from Molecular Revolution in Brazil Following Brazil's first democratic election after two decades of military dictatorship, French philosopher Félix Guattari traveled through Brazil in 1982 with Brazilian psychoanalyst Suely Rolnik and discovered an exciting, new political vitality. In the infancy of its new republic, Brazil was moving against traditional hierarchies of control and totalitarian regimes and founding a revolution of ideas and politics. Molecular Revolution in Brazil documents the conversations, discussions, and debates that arose during the trip, including a dialogue between Guattari and Brazil's future President Luis Ignacia Lula da Silva, then a young gubernatorial candidate. Through these exchanges, Guattari cuts through to the shadowy practices of globalization gone awry and boldly charts a revolution in practice. Assembled and edited by Rolnik, Molecular Revolution in Brazil is organized thematically; aphoristic at times, it presents a lesser-known, more overtly political aspect of Guattari's work. Originally published in Brazil in 1986 as Micropolitica: Cartografias do desejo, the book became a crucial reference for political movements in Brazil in the 1980s and 1990s. It now provides English-speaking readers with an invaluable picture of the radical thought and optimism that lies at the root of Lula's Brazil.

Author: Gene Levinson
Publisher: World Scientific
ISBN: 1786347288
Category : Science
Languages : en
Pages : 498

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Book Description
Rethinking Evolution links Darwin's early insights to the molecular realm inside living cells. This updated evolutionary synthesis provides an accessible explanation for biological complexity that cuts through the confusion surrounding evolutionary theory in a practical way.In addition to a wide-ranging survey of proposed updates to the modern synthesis, this title provides extraordinary new insights including emergent evolutionary potential and the generative phenotype. Drawing on well-characterized empirical facts, Rethinking Evolution transcends classical Darwinian natural selection while retaining those core principles that have stood the test of time.The updated synthesis brings a broad spectrum of specialized research together to provide a more plausible naturalistic explanation for biological evolution than ever before. Perspectives ranging from the role of energy in the origin of life to the networks of protein-DNA interactions that govern multicellular development are woven together in a robust conceptual fabric consistent with 21st century cutting-edge research.Inspired in part by the surprising ways that DNA sequences change — such as his early discovery of a fundamental mispairing mechanism by which DNA sequences expand — and drawing on a career's worth of experience both as a research scientist as well as a biology and chemistry tutor — the author provides an engaging account that is essential reading — both for the public awareness and understanding of the science of evolution and for students and professionals in the biomedical sciences.Related Link(s)

Author: G. Ledyard Stebbins
Publisher: UNC Press Books
ISBN: 1469622858
Category : Science
Languages : en
Pages : 165

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Book Description
In this incisive book, a distinguished geneticist has succeeded in relating the extraordinary biological discoveries of the last two decades to the basic questions about the origin and evolution of life on earth. The "molecular revolution" in biology--culminating in the discovery of the relations of the giant molecules of living matter--the operation of the genetic code, and the relational order in the biological world are all considered. Originally published in 1969. A UNC Press Enduring Edition -- UNC Press Enduring Editions use the latest in digital technology to make available again books from our distinguished backlist that were previously out of print. These editions are published unaltered from the original, and are presented in affordable paperback formats, bringing readers both historical and cultural value.

Author: Roderick D.M. Page
Publisher: John Wiley & Sons
ISBN: 1444313363
Category : Science
Languages : en
Pages : 352

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Book Description
The study of evolution at the molecular level has given the subject of evolutionary biology a new significance. Phylogenetic 'trees' of gene sequences are a powerful tool for recovering evolutionary relationships among species, and can be used to answer a broad range of evolutionary and ecological questions. They are also beginning to permeate the medical sciences. In this book, the authors approach the study of molecular evolution with the phylogenetic tree as a central metaphor. This will equip students and professionals with the ability to see both the evolutionary relevance of molecular data, and the significance evolutionary theory has for molecular studies. The book is accessible yet sufficiently detailed and explicit so that the student can learn the mechanics of the procedures discussed. The book is intended for senior undergraduate and graduate students taking courses in molecular evolution/phylogenetic reconstruction. It will also be a useful supplement for students taking wider courses in evolution, as well as a valuable resource for professionals. First student textbook of phylogenetic reconstruction which uses the tree as a central metaphor of evolution. Chapter summaries and annotated suggestions for further reading. Worked examples facilitate understanding of some of the more complex issues. Emphasis on clarity and accessibility.

Author: B. Schierwater
Publisher: Birkhäuser
ISBN: 3034875274
Category : Science
Languages : en
Pages : 615

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Book Description
The past 25 years have witnessed a revolution in the way ecologists and evolutionary biologists approach their disciplines. Modern molecular techniques are now reshaping the spectrum of questions that can be addressed while studying the mechanisms and consequences of the ecology and evolution of living organisms. "Molecular Ecology and Evolution: Approaches and Applications" describes, from a molecular perspective, several methodological and technical approaches used in the fields of ecology, evolution, population biology, molecular systematics, conservation genetics, and development. Modern techniques are introduced, and older, more classic ones refined. The advantages, limitations, and potentials of each are discussed in detail, and thereby illustrate the widening range of cross-field research and applications which this modern technology is stimulating. This book will serve as an important textbook for graduate and advanced undergraduate students, and as a key reference work for researchers