Genetically Modified Mosquitoes for Malaria Control PDF Download
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Author: Christophe Boete
Publisher: CRC Press
ISBN:
Category : Medical
Languages : en
Pages : 198
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Book Description
This book describes the epidemiological and evolutionary consequences of the use of genetically modified (GM) mosquitoes as well as research orientations and ethical issues concerning the use of GM mosquitoes. It also includes discussion on transgenic mosquitoes for malaria control.
Author: Christophe Boete
Publisher: CRC Press
ISBN:
Category : Medical
Languages : en
Pages : 198
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Book Description
This book describes the epidemiological and evolutionary consequences of the use of genetically modified (GM) mosquitoes as well as research orientations and ethical issues concerning the use of GM mosquitoes. It also includes discussion on transgenic mosquitoes for malaria control.
Author:
Publisher: World Health Organization
ISBN: 9240013156
Category : Medical
Languages : en
Pages : 7
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Book Description
Author: Zach N. Adelman
Publisher: Academic Press
ISBN: 0128004053
Category : Medical
Languages : en
Pages : 487
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Book Description
Genetic Control of Malaria and Dengue focuses on the knowledge, technology, regulation and ethics of using genetically modified mosquitoes to interrupt the transmission of important vector-borne diseases including Malaria. It contains coverage of the current state of knowledge of vector-borne diseases and how they are currently controlled; vaccine, drug and insecticide development; various strategies for altering the genome of mosquitoes in beneficial ways; and the regulatory, ethical and social environment concerning these strategies. For more than five decades, the prospect of using genetically-modified mosquitoes to control vector-borne disease transmission has been a purely hypothetical scenario. We simply did not have the technology or basic knowledge to be able to do it. With the explosion of field trials and potential interventions in development, Genetic Control of Malaria and Dengue provides a comprehensive overview of research in genetics, microbiology, virology, and ecology involved in the development and implementation of genetic modification programs for virus and disease control. This book is meant to provide a practical guide to researchers, regulators and the general public about how this technology actually works, how it can be improved, and what is still unknown. - Includes coverage of vectorial capacity, critical to understanding vector-borne disease transmission - Provides a summary of the concepts of both population suppression and population replacement - Contains pivotal coverage of ethical and ecological ramifications of genetics-based control strategies
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309437873
Category : Science
Languages : en
Pages : 231
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Book Description
Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators.
Author: Melissa R. Marselle
Publisher: Springer
ISBN: 3030023184
Category : Medical
Languages : en
Pages : 494
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Book Description
This open access book identifies and discusses biodiversity’s contribution to physical, mental and spiritual health and wellbeing. Furthermore, the book identifies the implications of this relationship for nature conservation, public health, landscape architecture and urban planning – and considers the opportunities of nature-based solutions for climate change adaptation. This transdisciplinary book will attract a wide audience interested in biodiversity, ecology, resource management, public health, psychology, urban planning, and landscape architecture. The emphasis is on multiple human health benefits from biodiversity - in particular with respect to the increasing challenge of climate change. This makes the book unique to other books that focus either on biodiversity and physical health or natural environments and mental wellbeing. The book is written as a definitive ‘go-to’ book for those who are new to the field of biodiversity and health.
Author: W. Takken
Publisher: Springer Science & Business Media
ISBN: 9781402015854
Category : Science
Languages : en
Pages : 248
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Book Description
This book is the reflection of a workshop, held in June 2002. Experts on mosquito ecology met for the first time to discuss the current knowledge of mosquito ecology with respect to GM-insect technology. Emphasis of the workshop was on evaluating how human health and natural ecosystems, including target wild-mosquito populations, will respond to the invasion of GM vectors. This volume will stimulate discussion by clearly showing the importance of vector ecology for prevention of vector-borne diseases.
Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241547871
Category : Medical
Languages : en
Pages : 159
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Book Description
This publication is intended to contribute to prevention and control of the morbidity and mortality associated with dengue and to serve as an authoritative reference source for health workers and researchers. These guidelines are not intended to replace national guidelines but to assist in the development of national or regional guidelines. They are expected to remain valid for five years (until 2014), although developments in research could change their validity.--Publisher's description.
Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241549653
Category : Medical
Languages : en
Pages : 242
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Book Description
This toolkit for integrated vector management (IVM) is designed to help national and regional programme managers coordinate across sectors to design and run large IVM programmes. It is an extension of earlier guidance and teaching material published by the World Health Organization (WHO): Handbook for integrated vector management Monitoring and evaluation indicators for integrated vector management Guidance on policy-making for integrated vector management and Core structure for training curricula on integrated vector management. The toolkit provides the technical detail required to plan implement monitor and evaluate an IVM approach. IVM can be used when the aim is to control or eliminate vector-borne diseases and can also contribute to insecticide resistance management. This toolkit provides information on where vector-borne diseases are endemic and what interventions should be used presenting case studies on IVM as well as relevant guidance documents for reference. The diseases that are the focus of this toolkit are malaria lymphatic filariasis dengue leishmaniasis onchocerciasis human African trypanosomiasis and schistosomiasis. It also includes information on other viral diseases (Rift Valley fever West Nile fever Chikungunya yellow fever) and trachoma. If other vector-borne diseases appear in a country or area vector control with an IVM approach should be adopted as per national priorities. Malaria as one of the most important vector-borne diseases in sub-Saharan Africa is the main focus of this document. Programmes targeting other vector-borne diseases can learn from the experiences gained from malaria vector control and presented here.
Author: World Health Organization
Publisher:
ISBN:
Category : Technology & Engineering
Languages : en
Pages : 288
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Book Description
Author: Graham Matthews
Publisher: John Wiley & Sons
ISBN: 1119950333
Category : Science
Languages : en
Pages : 242
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Book Description
Diseases transmitted by insects continue to have a major impact on human populations. Malaria, dengue, onchocerciasis, sleeping sickness and leishmaniasis all adversely affect man. Malaria is one of the most important causes of child mortality and reduces economic development in many countries, with agricultural productivity often greatly reduced, as many vectors are active in the wet season favourable for crop production. Vector control is crucial to reduce the extent to which drugs are needed to treat the diseases, as the parasite can become resistant, or the drugs are often too expensive for those living in rural areas and urban slums most affected by these diseases. Chemical control of vectors is often the only method that can reduce vector populations in a disease epidemic, but with vectors developing resistance to insecticides, there is increasing awareness that a single control method is often insufficient and also that chemical control must be integrated where possible with other control measures. In Integrated Vector Management, Graham Matthews covers the main chemical methods of vector control, including the use of indoor residual spraying, space treatments, the use of treated bed nets and larviciding, but also stresses the importance of drainage schemes and improvement of houses to prevent access of indoor vectors, techniques that have largely been responsible for reducing the risk of vector borne diseases in Europe and the USA. This book combines practical information from successful vector control programmes, including early use of DDT, and recent research into a vital resource for all those now involved in combating insect vector borne diseases. Integrated Vector Management is an essential tool, not only for medical entomologists and those directly involved in government health departments, but also for all those who provide the skills and management needed to operate successful area-wide vector management programmes. Libraries in all universities and research establishments world-wide, where biological sciences, medicine and agriculture are studied and taught should have multiple copies of this important book.
