Epistasis and the Evolutionary Process PDF Download
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Author: Jason B. Wolf
Publisher: Oxford University Press, USA
ISBN: 9780195128062
Category : Science
Languages : en
Pages : 348
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Book Description
Over the last two decades, research into epistasis has seen explosive growth and has moved the focus of research in evolutionary genetics from a traditional additive approach. We now know the effects of genes are rarely independent, and to reach a fuller understanding of the process of evolution we need to look at gene interactions as well as gene-environment interactions. This book is an overview of non-additive evolutionary genetics, integrating all work to date on all levels of evolutionary investigation of the importance of epistasis in the evolutionary process in general. It includes a historical perspective on this emerging field, in-depth discussion of terminology, discussions of the effects of epistasis at several different levels of biological organization and combinations of theoretical and experimental approaches to analysis.
Author: Jason B. Wolf
Publisher: Oxford University Press, USA
ISBN: 9780195128062
Category : Science
Languages : en
Pages : 348
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Book Description
Over the last two decades, research into epistasis has seen explosive growth and has moved the focus of research in evolutionary genetics from a traditional additive approach. We now know the effects of genes are rarely independent, and to reach a fuller understanding of the process of evolution we need to look at gene interactions as well as gene-environment interactions. This book is an overview of non-additive evolutionary genetics, integrating all work to date on all levels of evolutionary investigation of the importance of epistasis in the evolutionary process in general. It includes a historical perspective on this emerging field, in-depth discussion of terminology, discussions of the effects of epistasis at several different levels of biological organization and combinations of theoretical and experimental approaches to analysis.
Author: Alex Thomas Kalinka
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Author: Alex Thomas Kalinka
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Douglas W. Morris
Publisher: Oxford University Press (UK)
ISBN: 0198568800
Category : Nature
Languages : en
Pages : 282
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Book Description
This book provides a perspective on adaptive evolution.
Author: Graham Bell
Publisher: Springer Science & Business Media
ISBN: 146155991X
Category : Science
Languages : en
Pages : 397
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Book Description
This new textbook for students taking courses in evolution is addressed to one of the most difficult questions evolutionary biology, that of selection. Covering both artificial and natural selection, the author has written a short, readable text that will appeal to students and professionals alike. how the nature of the process determines the nature of evolutionary change.
Author: Onuralp Söylemez
Publisher:
ISBN:
Category :
Languages : en
Pages : 144
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Book Description
The role of epistasis – inter-dependent contributions of alleles to fitness – in shaping genetic variation within and between populations is an important question in evolutionary biology with significant implications for our understanding of the factors contributing to phenotypic variation. While epistasis has been shown to play an important role in evolutionary processes such as speciation and adaptive evolution, many aspects of this role remains poorly understood. In particular, there is much debate on whether observing prevalent epistasis in evolution can be taken as evidence for functional epistasis that is relevant to selectable variation. Here, we studied the nature of epistasis in protein evolution, and found a high prevalence of epistatic interactions between amino acid sites in the human genome. We showed that these interactions can help improve accuracy of predicting the impact of genetic variation on the protein structure and function. We also showed that hypothesis-driven search for epistasis in natural populations can detect genomic signatures of epistasis in humans.
Author: William F. Harms
Publisher: Cambridge University Press
ISBN: 1139451626
Category : Science
Languages : en
Pages : 282
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Book Description
This book is intended to help transform epistemology - the traditional study of knowledge - into a rigorous discipline by removing conceptual roadblocks and developing formal tools required for a fully naturalized epistemology. The evolutionary approach which Harms favours begins with the common observation that if our senses and reasoning were not reliable, then natural selection would have eliminated them long ago. The challenge for some time has been how to transform these informal musings about evolutionary epistemology into a rigorous theoretical discipline capable of complementing current scientific studies of the evolution of cognition with a philosophically defensible account of meaning and justification.
Author: Charles W. Fox
Publisher: Oxford University Press
ISBN: 9780199775040
Category : Science
Languages : en
Pages : 618
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Book Description
Charles Fox and Jason Wolf have brought together leading researchers to produce a cutting-edge primer introducing readers to the major concepts in modern evolutionary genetics. This book spans the continuum of scale, from studies of DNA sequence evolution through proteins and development to multivariate phenotypic evolution, and the continuum of time, from ancient events that lead to current species diversity to the rapid evolution seen over relatively short time scales in experimental evolution studies. Chapters are accessible to an audience lacking extensive background in evolutionaryy genetics but also current and in-depth enough to be of value to established researchers in evolution biology.
Author: Theodore Garland
Publisher: Univ of California Press
ISBN: 052094447X
Category : Science
Languages : en
Pages : 750
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Book Description
Experimental approaches to evolution provide indisputable evidence of evolution by directly observing the process at work. Experimental evolution deliberately duplicates evolutionary processes—forcing life histories to evolve, producing adaptations to stressful environmental conditions, and generating lineage splitting to create incipient species. This unique volume summarizes studies in experimental evolution, outlining current techniques and applications, and presenting the field’s full range of research—from selection in the laboratory to the manipulation of populations in the wild. It provides work on such key biological problems as the evolution of Darwinian fitness, sexual reproduction, life history, athletic performance, and learning.
Author: Kai Hahlweg
Publisher: State University of New York Press
ISBN: 1438405391
Category : Philosophy
Languages : en
Pages : 624
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Book Description
This book provides the fullest philosophical examination of theories of evolutionary epistemology now available. Here for the first time are found major statements of new theories, new applications, and many new critical explorations. The book is divided into four parts: Part I introduces several new approaches to evolutionary epistemology; Part II attempts to widen the scope of evolutionary epistemology, either by tackling more traditional epistemological issues, or by applying evolutionary models to new areas of inquiry such as the evolution of culture or of intentionality; Part III critically discusses specific problems in evolutionary epistemology; and Part IV deals with the relationship of evolutionary epistemology to the philosophy of mind. Because of its intellectual depth and its breadth of coverage, Issues in Evolutionary Epistemology will be an important text in the field for many years to come.
