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Author: David Shugar
Publisher:
ISBN:
Category : Nature
Languages : en
Pages : 378
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Author: David Shugar
Publisher:
ISBN:
Category : Nature
Languages : en
Pages : 378
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Book Description
Author: C. C. Rider
Publisher: Springer Science & Business Media
ISBN: 9401094470
Category : Science
Languages : en
Pages : 81
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Book Description
Isoenzymes were 'discovered' 20 years ago and were at first regarded as interesting but rare occurrences. Since then a wealth of information on enzyme heterogeneity has accrued and it now seems likely that at least half of all enzymes exist as isoenzymes. This is important in many areas of biological and medical science. Thus isoenzyme studies have provided the main experimental substance for the neutral drift controversy in genetics and evolution; they have greatly extended our understanding of metabolic regulation not only in animals but also in bacteria and plants; their existence has made available a multitude of highly sensitive markers for the study of differentiation and development, as well as providing indices of aberrant gene expression in carcinogenesis and other pathological processes. Iso enzymes are also being used increasingly in diagnostic clinical bio chemistry. It is surprising that this phenomenon which affects such a high pro portion of enzymes and is clearly important in biochemistry should receive such scant attention in the standard textbooks of that subject, the formal treatment of isoenzymology in these rarely exceeding one or two pages. This may be because the 'pure biochemist' has tended to regard variation in enzyme properties between tissues more as an unwanted complication than as a potential source of insight into diversity of biological function.
Author: D. W. Moss
Publisher: Springer Science & Business Media
ISBN: 9400958862
Category : Science
Languages : en
Pages : 266
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Book Description
The increased interest in multiple forms of enzymes that began with the application of new methods of fractionation to preparations of enzymes and other proteins some 25 years ago led quickly to an appreciation that the existence of enzymes in multiple forms, or isoenzymes, is a general phenomenon. The results of pioneering studies and those which followed in the early years of isoenzyme research consisted, not surprisingly, mainly of descriptions of the existence and characteristics of hetero geneity in various enzyme systems. Summaries of these results were provided in books such as J . H. Wilkinson's I soenzymes, the first edition of which appeared in 1965. Some clearer ideas of the nature of the phenomena had become apparent by the time that the second edition of Isoenzymes was called for in 1970, and a limited use of the word isoenzymes itself, to describe only certain of the various categories of enzyme multiplicity then recognized, was already being proposed. Nevertheless, a largely enzyme-by-enzyme oTganization of the contents of the book was still appropriate. Considerable advances, both experimental and conceptual, were made in isoenzyme research in the 1970s, and in 1977 Professor Wilkinson suggested to the present author that these should be taken into account in a joint revision of Isoenzymes. Professor Wilkinson's untimely death put. an end to this project and the present book is therefore the work of a single author.
Author: Albert Latner
Publisher: Elsevier
ISBN: 0323156940
Category : Science
Languages : en
Pages : 301
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Book Description
Isoenzymes in Biology and Medicine attempts to give an account of the study of isoenzymes in relation to humans, animals, insects, higher plants, fungi, protozoa, algae, and bacteria. This book discusses the chemical structure, physiological aspects, metabolic role, and function of isoenzyme observations in genetic, ontogenic, and phylogenic studies. A detailed account of the use of isoenzyme in the diagnosis and pathogenesis of disease and control of therapy is also provided. This text likewise considers the isoenzymes of the oxidoreductases, transferases, and hydrolases, including its relation to clinical medicine. This publication is intended for biochemists, biologists, clinical biochemists and physicians.
Author: John HENRY WILKINSON
Publisher: Springer
ISBN: 1489968342
Category : Science
Languages : en
Pages : 380
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Author: Clement Markert
Publisher: Elsevier
ISBN: 0323141781
Category : Science
Languages : en
Pages : 1057
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Book Description
Isozymes, III: Developmental Biology contains manuscripts presented at the Third International Conference on isozymes convened in April 1974 at Yale University. Separating 61 manuscripts into chapters, this book begins by discussing the areas of ""isozymology"" that appear particularly promising for further developmental analysis. This text also looks into the role of isozymes as genetic markers in early mammalian development, as well as the mechanisms of intracellular enzyme localization. Significant topics on specific isozymes are given separately in other chapters.
Author: Boyer, Abb
Publisher: Academic Press
ISBN: 0080865801
Category : Science
Languages : en
Pages : 909
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Book Description
The Enzymes
Author: Clement Lawrence Markert
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 920
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Vol. 2.
Author:
Publisher: Academic Press
ISBN: 0080865895
Category : Science
Languages : en
Pages : 675
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The Enzymes
Author: Douglas E. Soltis
Publisher: Springer Science & Business Media
ISBN: 9400918402
Category : Science
Languages : en
Pages : 273
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Book Description
