Author: Parisa Pourattar
Publisher:
ISBN: 9781369060201
Category : Chitosan
Languages : en
Pages : 37
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Book Description
Periodontitis is a major chronic inflammatory disorder that can lead to the destruction of the periodontal tissues and, ultimately, tooth loss. It is a major cause of tooth loss in adults and a substantial public-health burden worldwide. There is thus a significant need for periodontal ligament (PDL) regeneration to enable functional mechanical support of tooth prostheses and prevent occlusal overloading. The goal of stem cell-based dental tissue engineering, is to create tooth-like structures using scaffold materials to guide the dental stem cells. Current resorbable membranes act as an epithelial tissue down-growth into the defect, favoring the regeneration of periodontal tissues. In order to develop synthetic grafts for these applications, different biocompatible materials have been used to fabricate fibers with different structures and morphologies. This study demonstrated the feasibility of using a composite material that combines the advantage of multiple materials to synthesize polyvinyl alcohol/ chitosan blend fiber scaffolds to promote PDL regeneration and to achieve a synthetic composite that match the native PDL modulus. Morphology, dispersibility, and mechanical properties of blend nanofibrous mats were characterized by scanning electron microscopy (SEM), Fourier transform infrared (FT-IR) spectroscopy and tensile test.
Author: Gayathri.K ,Sunanda Rao.K, P.L.Ravishankar
Publisher: BFC Publications
ISBN: 9363706281
Category : Medical
Languages : en
Pages : 87
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Book Description
The concept of scaffolds in tissue engineering has revolutionized the approach to periodontal therapy. This book delves into the various types of scaffolds, their biological and mechanical properties, and the innovative materials being utilized to enhance their effectiveness. This book addresses the integration of scaffold technology with other regenerative modalities such as growth factors, stem cells, and gene therapy. The synergistic effects of these combined approaches hold immense promise for the future of periodontal regeneration. This book covers topics related to the biological and mechanical aspects of scaffold use in regeneration .
Author: Kendal I Creber
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Clinical therapies for the treatment of periodontitis are unable to reproducibly stimulate regeneration of the periodontium. We assessed the use of a novel electrospun type I collagen scaffold containing recombinant periostin to stimulate regeneration of the periodontal ligament (PDL) and bone. Human PDL cells demonstrated the ability to form a mineralized matrix in vitro and reduced osteogenic potential with increased donor age. In vitro analysis indicated scaffolds were biocompatible, however, periostin did not significantly influence adhesion or growth. In the healing of fenestration defects in rats, type I collagen scaffolds (with and without periostin) initially delayed cell infiltration and increased M2 macrophage recruitment, indicating either an elevated healing response or foreign body reaction. The incorporation of periostin into scaffolds had a limited effect on inflammation, collagen synthesis, and bone formation in vivo. Further optimization of periostin concentration and/or scaffold design is required to determine whether recombinant periostin influences periodontal healing.
Author: Anton Sculean
Publisher: Quintessence Publishing (IL)
ISBN: 9781850971580
Category : Periodontal Diseases
Languages : en
Pages : 0
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Book Description
This text provides the clinician with an overview on the use of regenerative techniques in periodontology. The chapters are designed to cover the most important aspects related to anatomy, wound healing, regenerative materials, surgical techniques, and clinical applications as related to regenerative procedures.
Author: Elashri Chatterjee
Publisher: GRIN Verlag
ISBN: 3668711380
Category : Science
Languages : en
Pages : 131
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Book Description
Literature Review from the year 2016 in the subject Biology - Miscellaneous, grade: 1, , course: MASTERS OF DENTAL SURGERY, language: English, abstract: Tissue engineering applies the principles of Biology, Chemistry, Physics, and Engineering for the development of substitutes that replace, repair or enhance the biological function of diseased and damaged human body parts, by manipulating cells via their extracellular microenvironment. This three dimensional extracellular architecture ("scaffold") can be fabricated in the shape of the tissue we want to restore, with the help of either polymer hydrogel, self-assembly, non- woven matrix, nano-fibrous electrospun matrices, 3D weaving, or any other textile technology-based techniques, depending upon their structural and functional requirements. This concept in periodontics began with guided tissue regeneration, a mechanical approach utilizing non-resorbable membranes to regenerate periodontal defects. In dental implantology, guided bone regeneration membranes, with or without mechanical support, are used for bone augmentation.
Author: Brent Vernon
Publisher: Elsevier
ISBN: 0857091379
Category : Medical
Languages : en
Pages : 425
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Book Description
Novel injectable materials for non-invasive surgical procedures are becoming increasingly popular. An advantage of these materials include easy deliverability into the body, however the suitability of their mechanical properties must also be carefully considered. Injectable biomaterials covers the materials, properties and biomedical applications of injectable materials, as well as novel developments in the technology.Part one focuses on materials and properties, with chapters covering the design of injectable biomaterials as well as their rheological properties and the mechanical properties of injectable polymers and composites. Part two covers the clinical applications of injectable biomaterials, including chapters on drug delivery, tissue engineering and orthopaedic applications as well as injectable materials for gene delivery systems. In part three, existing and developing technologies are discussed. Chapters in this part cover such topics as environmentally responsive biomaterials, injectable nanotechnology, injectable biodegradable materials and biocompatibility. There are also chapters focusing on troubleshooting and potential future applications of injectable biomaterials.With its distinguished editor and international team of contributors, Injectable biomaterials is a standard reference for materials scientists and researchers working in the biomaterials industry, as well as those with an academic interest in the subject. It will also be beneficial to clinicians. - Comprehensively examines the materials, properties and biomedical applications of injectable materials, as well as novel developments in the technology - Reviews the design of injectable biomaterials as well as their rheological properties and the mechanical properties of injectable polymers and composites - Explores clinical applications of injectable biomaterials, including drug delivery, tissue engineering, orthopaedic applications and injectable materials for gene delivery systems
Author: Michael Lysaght
Publisher: Elsevier
ISBN: 0857090844
Category : Technology & Engineering
Languages : en
Pages : 313
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Book Description
The worldwide demand for organ transplants far exceeds available donor organs. Consequently some patients die whilst waiting for a transplant. Synthetic alternatives are therefore imperative to improve the quality of, and in some cases, save people's lives. Advances in biomaterials have generated a range of materials and devices for use either outside the body or through implantation to replace or assist functions which may have been lost through disease or injury. Biomaterials for artificial organs reviews the latest developments in biomaterials and investigates how they can be used to improve the quality and efficiency of artificial organs.Part one discusses commodity biomaterials including membranes for oxygenators and plasmafilters, titanium and cobalt chromium alloys for hips and knees, polymeric joint-bearing surfaces for total joint replacements, biomaterials for pacemakers, defibrillators and neurostimulators and mechanical and bioprosthetic heart valves. Part two goes on to investigate advanced and next generation biomaterials including small intestinal submucosa and other decullarized matrix biomaterials for tissue repair, new ceramics and composites for joint replacement surgery, biomaterials for improving the blood and tissue compatibility of total artificial hearts (TAH) and ventricular assist devices (VAD), nanostructured biomaterials for artificial tissues and organs and matrices for tissue engineering and regenerative medicine.With its distinguished editors and international team of contributors Biomaterials for artificial organs is an invaluable resource to researchers, scientists and academics concerned with the advancement of artificial organs. - Reviews the latest developments in biomaterials and investigates how they can be used to improve the quality and efficiency of artificial organs - Discusses commodity biomaterials including membranes for oxygenators and cobalt chromium alloys for hips and knees and polymeric joint-bearing surfaces for total joint replacements - Further biomaterials utilised in pacemakers, defibrillators, neurostimulators and mechanical and bioprosthetic heart valve are also explored
Author: Rachel J. Waddington
Publisher: John Wiley & Sons
ISBN: 1118741072
Category : Medical
Languages : en
Pages : 418
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Book Description
Tissue Engineering and Regeneration in Dentistry: Current Strategies presents a thorough update on the current advances, methods and understanding in tissue engineering in dentistry. It offers invaluable tools, case studies, and methodologies for undertaking research, including important biological and practical considerations to facilitate successful migration of research from the bench to the clinic. Offers detailed coverage of the basic underlying principles and scientific evidence, and includes protocols to highlight practical applications Written by an internationally renowned team of expert contributors A must-have read for researchers and specialist clinicians in tissue engineering, oral biology, dental materials science, periodontology and oral surgery
Author: Inamuddin
Publisher: John Wiley & Sons
ISBN: 1119654866
Category : Technology & Engineering
Languages : en
Pages : 544
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Book Description
The aim of this book is to explore the history, fundamentals, manufacturing processes, optimization parameters, and applications of electrospun materials. The book includes various types of electrospun materials such as antimicrobial, smart, bioinspired systems. It focuses on the many application areas for electrospun materials such as energy storage and harvesting, catalysis, biomedical including gene delivery and tissue engineering, separation, adsorption and water treatment technologies, packaging. The book emphasizes the enhanced sustainable properties of electrospun materials, with the challenges and future developments being discussed in detail. The chapters are written by top-class researchers and experts from throughout the world.
Author: Paulo Jorge Bártolo
Publisher: Springer Science & Business Media
ISBN: 0387929045
Category : Technology & Engineering
Languages : en
Pages : 345
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Book Description
Stereolithography: Materials, Processes and Applications will focus on recent advances in stereolithography covering aspects related to the most recent advances in the field, in terms of fabrication processes (two-photon polymerization, micro-stereolithography, infrared stereolithography and stereo-thermal-lithography), materials (novel resins, hydrogels for medical applications and highly reinforced resins with ceramics and metals), computer simulation and applications.
